Gene Environment interactions in Mental health trajectories of Youth

Informacje na temat projektu

Youth-GEMs

Identyfikator umowy o grant: 101057182

DOI

10.3030/101057182

Data podpisania przez KE 24 Maja 2022

Data rozpoczęcia 1 Czerwca 2022

Data zakończenia 31 Maja 2027

Finansowanie w ramach

• Health

Koszt całkowity

€ 8 121 855,00

Wkład UE

€ 8 107 980,00

Koordynowany przez

UNIVERSITEIT MAASTRICHT
Netherlands

CORDIS oferuje możliwość skorzystania z odnośników do publicznie dostępnych publikacji i rezultatów projektów realizowanych w ramach programów ramowych HORYZONT.

Odnośniki do rezultatów i publikacji związanych z poszczególnymi projektami 7PR, a także odnośniki do niektórych konkretnych kategorii wyników, takich jak zbiory danych i oprogramowanie, są dynamicznie pobierane z systemu OpenAIRE .

Rezultaty

Documents, reports (6)

Dissemination and Communication Strategy
Exploitation, Publication and IP Management Plan

Exploitation, Publication and IP Management Plan and guidelines

AI-informed set of predictive markers

AI-informed set of predictive markers for mental health trajectories in young people

Gene-environment interactions

Identification of gene-environment interactions driving mental health trajectories of young people

Dissemination and Communication Strategy – update
Mental health trajectories

Identification and characterisation of mental health trajectories in young people

Other (2)

Genetic scores– update

Genetic scores and components of trans-syndromal phenotypes of mental illness with developmental, cell-type and functional specificity – update

Genetic scores

Genetic scores and components of trans-syndromal phenotypes of mental illness with developmental, cell-type and functional specificity

Websites, patent fillings, videos etc. (1)

Project Website

Publication of the project website

Demonstrators, pilots, prototypes (1)

Prediction instrument for young people

AI-powered proof-of-concept prediction instrument for young people

Publikacje

Peer reviewed articles (13)

Bridging gaps in youth mental health care: YOUTHreach—a comprehensive European strategy

Autorzy: Thérèse van Amelsvoort, Anouk Boonstra, Karim Lekadir, Esmeralda Ruiz Pujadas, Matthew R. Broome, Sian Lowri Griffiths, Gary Donohoe, Arne Popma, Giovanni de Girolamo, Covadonga M. Díaz-Caneja, Anna-Kaisa Oidermaa, Andreas Bechdolf, Silvia Evers, Ghislaine van Mastrigt, Dorothee Horstkötter, Ricky Janssen, Maria Bulgheroni, David McDaid, Jan R. Boehnke, Patrick McGorry, Mario Alvarez Jimenez, null AEGEE, Anita Schick, Ulrich Reininghaus, Sophie Leijdesdorff, null null, Casper Crombach, Rianne Pellemans-van Rooijen, Flore Joskin, Lieke Maas, Ayshe Yaylali, Zjulie Rutten, Miriam D’Addazio, Federick Trisolini, Laura Lozzino, Mauro Percudani, Simona Barbera, Mariann Märtsin, Kristel Habicht-Spriit, Mari-Liis Kaldoja, Rebekah Amos, Camilla Carr, Carla Searle, Balachandran Kumarendran, Carlos Martin Isla, Cristian Izquierdo, Carla Searle, Balachandran Kumarendran, Carlos Martin Isla, Cristian Izquierdo, Elena Novelli, Maeve Dwan-O’Reilly, Tom Freeney, Jeff Moore, Jim Lyng, Anna Kessler, Leonie Burghoff, Frederike Schirmbeck, Shaminka Mangelsdorfo, Shane Cross, Fenna Hellegers, Marilon van Doorn, Sascha Struijs, Esmee Otten, Claudi Bockting, Celso Arango, Raquel Rodríguez, Laura Roldán, Jule Leickert, Petra Gommaar, A-La Park
Opublikowane w: European Child & Adolescent Psychiatry, 2026, ISSN 1018-8827
Wydawca: Springer Science and Business Media LLC
DOI: 10.1007/S00787-026-03033-3

Gender differences in the associations between childhood adversity and psychopathology in the general population

Autorzy: Thanavadee Prachason; Irem Mutlu; Laura Fusar-Poli; Claudia Menne-Lothmann; Jeroen Decoster; Ruud van Winkel; Dina Collip; Philippe Delespaul; Marc De Hert; Catherine Derom; Evert Thiery; Nele Jacobs; Marieke Wichers; Jim van Os; Bart P. F. Rutten; Lotta-Katrin Pries; Sinan Guloksuz
Opublikowane w: Soc Psychiatry Psychiatr Epidemiol, 2023, ISSN 1433-9285
Wydawca: Elsevier
DOI: 10.1007/s00127-023-02546-5

Exposome and Trans-syndromal Developmental Trajectories Toward Psychosis

Autorzy: Ran Barzilay, Lotta-Katrin Pries, Tyler M Moore, Raquel E Gur, Jim van Os, Bart P F Rutten, Sinan Guloksuz
Opublikowane w: Biol Psychiatry Glob Open Sci, 2022, ISSN 2667-1743
Wydawca: Elsevier
DOI: 10.1016/j.bpsgos.2022.05.001

American Journal of Psychiatry

Autorzy: Bart P.F. Rutten; Suzanne C. van Bronswijk
Opublikowane w: Am J Psychiatry, 2022, ISSN 0002-953X
Wydawca: American Psychiatric Publishing, Inc.
DOI: 10.1176/APPI.AJP.20220783

Longitudinal Prediction of Mental Health Outcomes in Vulnerable Youth using Machine Learning

Autorzy: Esmeralda Ruiz Pujadas, Covadonga M. Díaz-Caneja, Dejan Stevanovic, Marta Ferrer Quintero, Carlos Martín-Isla, Jerónimo Hernández-González, Angelica Atehortúa, Noussair Lazrak, Lotta Pries, Philippe Delespaul, Marina Camacho, Sinan Gülöksüz, Bart P. F. Rutten, Karim Lekadir
Opublikowane w: Cognitive Computation, Numer 17, 2025, ISSN 1866-9956
Wydawca: Springer Science and Business Media LLC
DOI: 10.1007/S12559-025-10509-Y

Clinical predictors of readmission to psychiatric inpatient care: A 20-year follow up study of former adolescent inpatients

Autorzy: Jenni Leppanen, Valentina Kieseppä, Siiri Eskelinen, Veera Säynäjäkangas, Bart Rutten, Sinan Gülöksüz, Anu-Helmi Halt, Pirkko Riipinen, Covadonga M. Díaz-Caneja, Ian Kelleher
Opublikowane w: Psychiatry Research, Numer 351, 2026, ISSN 0165-1781
Wydawca: Elsevier BV
DOI: 10.1016/J.PSYCHRES.2025.116606

The why and the how of transdiagnostic clinical research in youth psychiatry

Autorzy: Covadonga M. Díaz-Caneja, Sinan Guloksuz
Opublikowane w: European Neuropsychopharmacology, Numer 82, 2024, ISSN 0924-977X
Wydawca: Elsevier BV
DOI: 10.1016/J.EURONEURO.2024.02.012

Epigenetic biomarkers of inflammation in studies on mental health: Current applications, limitations, and future directions

Autorzy: Winni Schalkwijk, Lot D. de Witte, Frederieke A.J. Gigase, Charlotte A.M. Cecil, Matthew Suderman, Sinan Gülöksüz, Bart P.F. Rutten, Marco P. Boks
Opublikowane w: Brain, Behavior, and Immunity, Numer 133, 2026, ISSN 0889-1591
Wydawca: Elsevier BV
DOI: 10.1016/J.BBI.2025.106245

Decision-making on an AI-supported youth mental health app: A multilogue among ethicists, social scientists, AI-researchers, biomedical engineers, young experiential experts, and psychiatrists

Autorzy: Dorothee Horstkötter; Mariël Kanne; Simona Karbouniaris; Noussair Lazrak; Maria Bulgheroni; Ella Sheltawy; Laura Giani; Margherita La Gamba; Esmeralda Ruiz Pujadas; Marina Camacho; Finty Royle; Irene Baggetto; Sinan Gülöksüz; Bart Rutten; Jim van Os
Opublikowane w: Journal of Responsible Technology, 2025, ISSN 2666-6596
Wydawca: Elsevier Ltd
DOI: 10.1016/J.JRT.2025.100119

Situating problematic gaming and psychotic-like experiences in the adolescent landscape of affordances: A cohort study

Autorzy: Vincent Paquin, Zoey Lavallee, Maxime Huot-Lavoie, Benson S. Ku, Covadonga M. Díaz-Caneja, Sinan Gülöksüz
Opublikowane w: Journal of Behavioral Addictions, Numer 15, 2026, ISSN 2062-5871
Wydawca: Akademiai Kiado Zrt.
DOI: 10.1556/2006.2025.00094

Do psychotic symptoms predict future psychotic disorders in adolescent psychiatry inpatients? A 17-year cohort study

Autorzy: Valentina Kieseppä, Ulla Lång, Colm Healy, Kirstie O’Hare, Covadonga M. Díaz-Caneja, Sinan Gülöksüz, Bart P. F. Rutten, Mary Cannon, Anu-Helmi Halt, Pirkko Riipinen, Ian Kelleher
Opublikowane w: Psychological Medicine, Numer 55, 2025, ISSN 0033-2917
Wydawca: Cambridge University Press (CUP)
DOI: 10.1017/S003329172500073X

Cell-type-specific DNA methylation dynamics in the prenatal and postnatal human cortex

Autorzy: Alice Franklin; Jonathan P. Davies1 ∙ Nicholas E. Clifton1 ∙ Emma Dempster1 ∙ Eilis Hannon1 ∙ Jonathan Mill
Opublikowane w: Cell genomics, ISSN 2666-979X
Wydawca: Elsevier Inc.
DOI: 10.1016/J.XGEN.2025.101010

GxE in psychiatry — challenges and opportunities

Autorzy: Sanne Berkers, Elisabeth Binder
Opublikowane w: Current Opinion in Genetics & Development, Numer 98, 2026, ISSN 0959-437X
Wydawca: Elsevier BV
DOI: 10.1016/J.GDE.2026.102452