European Commission logo
español español
CORDIS - Resultados de investigaciones de la UE
CORDIS

Training AlliancE for Novel Microbiome-Modulating TherapieS

Descripción del proyecto

Una plataforma de formación para el descubrimiento de fármacos centrada en modificaciones terapéuticas de la microbiota

El objetivo del proyecto TALENTS, financiado por las Acciones Marie Skłodowska-Curie, es establecer una alianza internacional para la formación interdisciplinaria de quince doctorandos como investigadores sobre fármacos de nueva generación. Los proyectos individuales están estructurados de tal forma que se centran en la investigación del microbioma y las modificaciones terapéuticas de la microbiota, alternativas a los antibióticos tradicionales para reducir el riesgo de desarrollar resistencia y para administrar nuevos agentes terapéuticos. El objetivo global es desarrollar nuevos modelos de enfermedades y métodos analíticos. Al desvelar las correlaciones y vínculos entre la microbiota y el origen de la enfermedad, TALENTS avanzará hacia el descubrimiento de innovadores tratamientos moduladores del microbioma.

Objetivo

TALENTS aims to build up an international programme for interdisciplinary and transsectorial training of 15 doctoral candidates (DCs) as needed for the next generation of drug researchers. Research projects are structured in 3 clusters (PCs): PC1 will investigate the microbiome by transcriptomic and metagenomic analysis of diseases to identify and isolate microorganisms/metabolites for therapeutically modifying the microbiota. PC2 will focus on pathoblockers targeting virulence factors as alternative to traditional antibiotics with lower risk of resistance development. PC3 will address the delivery needs across biological barriers, to achieve efficient and targeted transport to the site of action. Throughout the PC structure of 15 individual, but interconnected research projects, we aim to develop and exchange disease models, analytical methods and microbiome-related results. By generating knowledge on correlations and causalities between microbiota and disease TALENTS will advance the development of novel microbiome-modulating therapies
TALENTS is builds on an earlier joint venture of Saarland University, University Clinics Saarland and Helmholtz Institute for Pharmaceutical Research Saarland to foster transdisciplinary doctoral training between different faculties and institutions. In addition, TALENTS is intersectorial by implementing a unique supervision structure for each DC with an external expert advisor and translation-oriented training for individual career development, also including secondments in a complementary industrial or clinical sector. Working on challenging research projects, the candidates will acquire specific knowledge and skills at the interface of clinical medicine, microbiology and pharmaceutical science, pivotal for state-of-the-art infection research and microbiome interventions.
By collaborations of experts from natural sciences, medicine, and bioinformatics, TALENTS provides high-level multidisciplinary and intersectorial training.

Coordinador

UNIVERSITAT DES SAARLANDES
Aportación neta de la UEn
€ 1 512 000,00
Dirección
CAMPUS
66123 Saarbrucken
Alemania

Ver en el mapa

Región
Saarland Saarland Regionalverband Saarbrücken
Tipo de actividad
Higher or Secondary Education Establishments
Enlaces
Coste total
Sin datos

Socios (16)