MACRAMÉ’s Central Objective is to:
• detect, characterise and quantify AdMas during handling and processing along the product life-cycle,
• assess potential impacts on (human) health and the environment in intended or unintended exposure situations (i.e. ‘Exposure Points’) in the product value-chain,
• advance the wide-spread applicability of the developed test and characterisation methods, by demonstrating their effectiveness and efficiency in the context of existing, market-relevant industrial AdMas containing products, and
• prepare and initiate standardisation, harmonisation and technological & regulatory validation of test- and characterisation-methods.
Specific Objectives & R&I targets:
Specific Objective 1: Interfacing Communities and Streamlining Methodological Approaches to assess the Risk of AdMa@CMs
Specific Objective 2: Assessment of market-relevant Exposure Points and representative Sampling along the Life-Cycle of five MACRAMÉ Use-Cases
Specific Objective 3: Characterisation - Development & Harmonisation of Methodological Approaches for the Identification, Physical-Chemical Characterisation and Quantification of inhalable AdMa@CMs
Specific Objective 4: Toxicity Tests - Development of new Advanced Methodologies & Harmonisation of existing Methodological Approaches for human and environmental Hazard Characterisation of inhalable AdMa@CMs
Specific Objective 5: Hazard Assessment - Development of the scientific Background to foster regulatory Acceptability of Methods and Methodologies for the Physical-Chemical and Hazard Characterisation of AdMa@CMs
Specific Objective 6: Establish improved Data-Reporting Guidelines and deliver harmonised, FAIR Data for the Characterisation of AdMas at different Life-Cycle Stages
Specific Objective 7: Translation of Detection, Characterisation and Test Methods and combined novel Methodological Approaches into Standards and OECD Test Guidelines & Guidance Documents
