iRISE has provided conceptual and methodological tools, including the iRISE glossary, which clarifies terms like "reproducibility", "replicability", and related key EDI concepts. Through comprehensive evaluation of the literature, we have identified 49 (potential) causes of irreproducibility and reviewed 50 measures of reproducibility, some of which are now being tested in real-world settings and linked to economic models. We also developed iRISE-SOLES (Systematic Online Living Evidence Summary), a systematically curated living summary of existing evidence on reproducibility interventions. iRISE-SOLES combines expert input and AI to summarise interventions. Users can identify evidence gaps through an online dashboard to support evidence-based decision-making across a broad range of stakeholders including researchers and policymakers.
To strengthen research culture, iRISE is embedding EDI principles into research practices by developing an assessment framework and examining how diversity in research teams impacts scientific integrity. This work lays the foundation for more inclusive and high-quality research across disciplines.
Engaging closely with stakeholders, iRISE is using Delphi processes and focus groups to prioritise practical tools such as methodological training and data management improvements, aiming to build a sustainable, stakeholder-driven model for enhancing research practices.
Furthermore, iRISE is running several intervention studies to test strategies for boosting reproducibility, including the use of automated screening tools, computational reproducibility checks, the EQIPD quality system, and statistical interventions. These studies will inform future approaches to improving research quality.
Finally, iRISE performs data management, communication, and knowledge sharing through an Open Knowledge Base, an active social media presence, and the coordination of a Stakeholder Forum to ensure continuous community engagement.
