DuraStore transitions DNA-based storage from a static medium to a dynamic, sustainable "molecular drive." While current technologies rely on destructive sampling and energy-intensive thermocycling, DuraStore moves the field closer to the performance of conventional data storage technologies through several key innovations.
Existing DNA storage suffers from material depletion during the "read" process. DuraStore is the only system promising entirely lossless, non-destructive access. Our regeneratable molecular drive enables random access and repetitive operations without the material loss typical of PCR-based retrieval. We have validated this by successfully demonstrating dataset loading and targeted access, confirming the system's ability to handle complex data structures.
We demonstrated that write, read, and delete operations can be performed chemically at ambient temperatures (≤37°C). This eliminates high-temperature steps, offering a strategy with two orders of magnitude less energy consumption than state-of-the-art approaches.
Furthermore, DuraStore is the only DNA-based architecture implementing a scalable targeted delete operation, critical for GDPR compliance. This allows selective removal of data blocks without compromising library integrity, addressing a major barrier to the commercial adoption of biological storage.
Beyond storage, we are developing reversible DNA stabilizing agents providing high-performance protection against heat, radiation, and enzymatic degradation. Unlike silica-encapsulation, our approach ensures a seamless transition to downstream processes, making it ideal for medical or environmental samples. We have validated its enzymatic protection and are currently characterizing its our technologies shielding effects against other factors.
