Final Report Summary - TB-EURO-GEN (Genetic analysis of the host-pathogen interaction in tuberculosis)
This approach will lead to the discovery of genes involved in susceptibility / resistance to TB in humans. Deciphering effects of the natural variation between M. tuberculosis strains will help to identify virulence factors, and influence prognosis for TB patients. These results will improve our understanding of TB pathogenesis and may have impact on TB vaccine research, opening new targets for TB prevention.