Cel Influenza is an extremely contagious infection that is caused by distinct virus types and subtypes. Early diagnosis is crucial for disease treatment and control as it reduces the inappropriate use of antibiotics and provides the indication for antiviral therapy. Rapid diagnosis is also a key component of surveillance activity. This requires the ability to detect and accurately diagnose infection at or close to the source/outbreak with minimum delay, a tactic consistent with the global experience during the SARS epidemic in 2003. This experience underlines the need for specific, sensitive point-of-care testing capable of discriminating between influenza subtypes. None of the available influenza diagnostic assays combines a point-of-care format with the multiplex capability to identify a large repertoire of human and animal viruses. This project exploits the knowledge and the expertise of the partners to convert microarray assays, that have a powerful multiplex capability but are laborious, complex and expensive to perform, into a simple, robust and affordable automated point-of-care system for the diagnosis of influenza. The system will utilize three components: 1) a microarray immunoassay that distinguishes influenza A and B virus as well as A subtypes; 2) an innovative self-contained disposable lateral-flow device that allows the addition of specimens and reagents in a temporally-controlled manner; 3) a robust automated processing reading instrument of novel conception that employs a low cost, high performance optical module. This project will provide small laboratories, health offices, veterinary clinics and outposts (airports) with the diagnostic capability of major research institutions and reference centres, thus providing better care for patients and most importantly, facilitating the implementation of surveillance activities and guiding response measures that are being built to face a possible influenza pandemic caused by a highly virulent virus. Dziedzina nauki medical and health scienceshealth sciencesinfectious diseasesRNA virusesinfluenzamedical and health scienceshealth sciencesinfectious diseasesRNA virusescoronaviruses Słowa kluczowe Bioinformatics Genomics Influenza Micro-array Point-of-care Proteomics Serodiagnosis Program(-y) FP7-HEALTH - Specific Programme "Cooperation": Health Temat(-y) HEALTH-2007-2.3.3-4 - Innovative point-of-care diagnostic tests for influenza Zaproszenie do składania wniosków FP7-HEALTH-2007-A Zobacz inne projekty w ramach tego zaproszenia System finansowania CP-TP - Collaborative Project targeted to a special group (such as SMEs) Koordynator UNIVERSITA DEGLI STUDI DI PERUGIA Wkład UE € 946 798,30 Adres PIAZZA DELL UNIVERSITA 1 06123 Perugia Włochy Zobacz na mapie Region Centro (IT) Umbria Perugia Rodzaj działalności Higher or Secondary Education Establishments Kontakt administracyjny Ennio Becchetti (Prof.) Linki Kontakt z organizacją Opens in new window Strona internetowa Opens in new window Koszt całkowity Brak danych Uczestnicy (5) Sortuj alfabetycznie Sortuj według wkładu UE Rozwiń wszystko Zwiń wszystko HEALTH PROTECTION AGENCY HPA Zakończenie uczestnictwa Zjednoczone Królestwo Wkład UE € 215 993,17 Adres BUCKINGHAM PALACE ROAD 151 SW1W 9SZ London Zobacz na mapie Rodzaj działalności Research Organisations Kontakt administracyjny David Conway (Mr.) Linki Kontakt z organizacją Opens in new window Strona internetowa Opens in new window Koszt całkowity Brak danych ISTITUTO SUPERIORE DI SANITA Włochy Wkład UE € 308 200,00 Adres Viale Regina Elena 299 00161 Roma Zobacz na mapie Region Centro (IT) Lazio Roma Rodzaj działalności Research Organisations Kontakt administracyjny Rosa Maria Martoccia (Dr.) Linki Kontakt z organizacją Opens in new window Strona internetowa Opens in new window Koszt całkowity Brak danych PX'Therapeutics Francja Wkład UE € 193 125,00 Adres 15, rue des Martyrs 38027 GRENOBLE Zobacz na mapie Rodzaj działalności Private for-profit entities (excluding Higher or Secondary Education Establishments) Kontakt administracyjny Tristan Rousselle (Dr.) Linki Kontakt z organizacją Opens in new window Strona internetowa Opens in new window Koszt całkowity Brak danych MICROTEST MATRICES LTD Zjednoczone Królestwo Wkład UE € 822 676,53 Adres EXHIBITION ROAD, BESSEMER BUILDING SW7 2AZ LONDON Zobacz na mapie Region London Inner London — West Westminster Rodzaj działalności Private for-profit entities (excluding Higher or Secondary Education Establishments) Kontakt administracyjny Clelia Supparo (Ms.) Linki Kontakt z organizacją Opens in new window Strona internetowa Opens in new window Koszt całkowity Brak danych SEAC Włochy Wkład UE € 289 200,00 Adres Via de Prato 74 50041 CALENZANO- FIRENZE Zobacz na mapie Rodzaj działalności Private for-profit entities (excluding Higher or Secondary Education Establishments) Kontakt administracyjny Angelo Manzoni (Dr.) Linki Kontakt z organizacją Opens in new window Strona internetowa Opens in new window Koszt całkowity Brak danych