Skip to main content
Przejdź do strony domowej Komisji Europejskiej (odnośnik otworzy się w nowym oknie)
polski pl
CORDIS - Wyniki badań wspieranych przez UE
CORDIS
Zawartość zarchiwizowana w dniu 2024-06-18

Confocal impedance microscopy of cell interactions with surfaces

Cel

A confocal impedance microscope capable of producing two-dimensional electrical images and three-dimensional optical images of materials and cells simultaneously will be developed. The electrical images are produced using two closely related techniques. In formation about the local electrical impedance will be obtained using Scanning Photo-induce Impedance Microscopy; information about local electrical potentials and pH will be obtained from so-called Light-Addressable Potentiometric Sensors. Both techniques are based on photocurrent measurements at electrolyte-insulator semiconductor structures. Optical images will be measured by confocal microscopy.

Electrical and optical images will be used to monitor physiological processes such as signal transmission in neurons or metabolic processes. Using the new instrument, ion channel activity will be monitored in different parts of the cell at the interface between cell and surface, an area that is not accessible by traditional patch clamp techniques. For the design of new materials that promote tissue growth, the interaction between cells and surface is of great importance. The confocal impedance microscope will provide information about cell morphological and cytoskeletal changes and also changes in the impedance, i.e. transport properties of the cell membrane in the cell attachment area.

Dziedzina nauki (EuroSciVoc)

Słowa kluczowe

Temat(-y)

Zaproszenie do składania wniosków

FP6-2004-MOBILITY-7
Zobacz inne projekty w ramach tego zaproszenia

System finansowania

IIF - Marie Curie actions-Incoming International Fellowships

Koordynator

QUEEN MARY AND WESTFIELD COLLEGE
Wkład UE
Brak danych
Adres


Zjednoczone Królestwo
Koszt całkowity
Brak danych