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BiO-dOSimetric Tools for triagE to Responders

Obiettivo

The effective management of an incident involving exposure of large numbers of people to radioactive material, whether accidental or following malevolent use of radioactivity, requires a mechanism for rapid triage of exposed persons. The BOOSTER project addresses this requirement under Security Topic SEC-2009-4.3.2 – Bio-dosimetric tools to manage radiological casualties. Current biodosimetric approaches frequently involve cytogenetics. The analysis of dicentric/ ring chromosomes is the mechanism of choice for precise estimation of an individual’s exposure. Current optimisation of such analyses involves the automation of various steps in the process. However, chromosome analyses are performed on the first mitosis post-exposure and thus a significant limiting factor remains a cell culture step (2 days) that is impossible to reduce. New biodosimeters are required that may not bring the same precision as cytogenetic analysis but will permit triage in the first hours post-accident into three populations (i.e. to identify individuals that require no further intervention, those who require close follow-up and those who require hospitalisation). BOOSTER is a capability project designed to research and develop new bio-dosimetric tools in order to quickly evaluate the level of potential casualties, determine by appropriate sensors their consequences, allow an efficient triage of exposed people, integrate a useful and usable toolbox, train civil protection operators and define commercial exploitation potentialities. The BOOSTER project will use an integrated approach to deliver new bio-dosimetric tools. We propose to optimise existing tools for assessment of a radiological situation and to develop novel biodosimetric procedures for estimation of radiation exposure in cells from patients. These approaches will be combined in a prognostic toolkit that will allow effective management of exposed persons presenting at triage.

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FP7-SEC-2009-1
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Meccanismo di finanziamento

CP - Collaborative project (generic)

Coordinatore

COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES
Indirizzo
Rue Leblanc 25
75015 Paris 15
Francia

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Tipo di attività
Research Organisations
Contatto amministrativo
Brigitte Nicolas (Ms.)
Contributo UE
€ 973 137

Partecipanti (6)

NATIONAL UNIVERSITY OF IRELAND GALWAY
Irlanda
Contributo UE
€ 699 876
Indirizzo
University Road
H91 Galway

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Tipo di attività
Higher or Secondary Education Establishments
Contatto amministrativo
Roger Sweetman (Mr.)
KARLSRUHER INSTITUT FUER TECHNOLOGIE
Germania
Contributo UE
€ 501 750
Indirizzo
Kaiserstrasse 12
76131 Karlsruhe

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Tipo di attività
Higher or Secondary Education Establishments
Contatto amministrativo
Natascha Wallburg (Ms.)
IZOTOPKUTATO INTEZET - MAGYAR TUDOMANYOS AKADEMIA
Ungheria
Contributo UE
€ 281 500
Indirizzo
Konkoly Thege M. 29-33
1121 Budapest

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Tipo di attività
Research Organisations
Contatto amministrativo
Ildikó Grób
CANBERRA FRANCE
Francia
Contributo UE
€ 334 637
Indirizzo
Rue Des Hérons 1
78180 Montigny Les Bretonneux

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Tipo di attività
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Contatto amministrativo
Hervé Toubon (Mr.)
UNIVERSITAT POLITECNICA DE VALENCIA
Spagna
Contributo UE
€ 384 191
Indirizzo
Camino De Vera Sn Edificio 3a
46022 Valencia

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Tipo di attività
Higher or Secondary Education Establishments
Contatto amministrativo
José Antonio Pérez Garcia (Mr.)
ORSZAGOS ATOMENERGIA HIVATAL
Ungheria
Contributo UE
€ 109 200
Indirizzo
Fenyes Adolf 4
1036 Budapest

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Tipo di attività
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Contatto amministrativo
Kristof Horvath (Dr.)