Obiettivo Organ transplantation is often the only life saving medical approach for several diseases, in spite of many associated problems (lack of organ donors, rejection, life-long heavy medication). The innovative therapeutic approach of the 21th century is focusing on bioartificial organs as an alternative solution.Tissue engineering and stem cell biology have uncovered groundbreaking opportunities for cellular re-programming, i.e. some cell types can be changed into a pluripotent stem cell (PSC) by over-expressing key transcription factors. These induced pluripotent stem cells (iPSC) share two key characteristics with embryonic stem cells (eSC): self-renewal and pluripotency (ability to differentiate to form any cell type in the human body). Crucially, they are generated from adult cells circumventing many ethical concerns associated with using human eSC. The discovery of human iPSC (hiPSC) enables the growth of an almost unlimited supply of a patient´s own cells, potentially conferring the ability to grow and regenerate tissues and organs from ‘self’, which is expected to resolve organ rejection-related issues. Similarly, recent developments in material science and nanobiotechnology resulted in engineered materials and devices (manipulated and controlled by physical and chemical means), with unique functional or analytical properties. NanoBio4Trans will merge hiPSC-, polymer hybrid scaffolds and biosensor technologies to develop new tools (beyond state-of-the-art) for use in transplantation and biomedical research. The international, trans-sectoral, and multidisciplinary consortium with complementary and leading expertise in material sciences, cell- and molecular biology, sensor technologies, and bioanalytics, aims at developing, optimising and validating a highly vascularised in vivo-like BAL as an extracorporeal bioartificial liver (EBAL), ready to be perfused with human blood plasma, and to be exploited in modern medical technology. Campo scientifico medical and health sciencesbasic medicinepharmacology and pharmacypharmaceutical drugsnatural sciencesbiological sciencescell biologymedical and health sciencesmedical biotechnologycells technologiesstem cellsmedical and health sciencesclinical medicinetransplantationmedical and health sciencesmedical biotechnologytissue engineeringbioartificial liver Programma(i) FP7-HEALTH - Specific Programme "Cooperation": Health Argomento(i) HEALTH.2012.1.4-2 - Medical technology for transplantation and bioartificial organs Invito a presentare proposte FP7-HEALTH-2012-INNOVATION-2 Vedi altri progetti per questo bando Meccanismo di finanziamento CP-FP - Small or medium-scale focused research project Coordinatore DANMARKS TEKNISKE UNIVERSITET Contributo UE € 1 716 653,00 Indirizzo ANKER ENGELUNDS VEJ 101 2800 Kongens Lyngby Danimarca Mostra sulla mappa Regione Danmark Hovedstaden Københavns omegn Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Jenny Emneus (Prof.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato Partecipanti (4) Classifica in ordine alfabetico Classifica per Contributo UE Espandi tutto Riduci tutto Takara Bio Europe AB Svezia Contributo UE € 1 315 690,00 Indirizzo Arvid Wallgrens backe 413 46 Göteborg Mostra sulla mappa Tipo di attività Private for-profit entities (excluding Higher or Secondary Education Establishments) Contatto amministrativo Karina Lövstedt (Ms.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato BIOMODICS APS Danimarca Contributo UE € 578 250,00 Indirizzo STENGARDS ALLE 31 A 2800 Kgs Lyngby Mostra sulla mappa Regione Danmark Hovedstaden Københavns omegn Tipo di attività Private for-profit entities (excluding Higher or Secondary Education Establishments) Contatto amministrativo Peter Thomsen (Dr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato LUXCEL BIOSCIENCES LTD Irlanda Contributo UE € 1 166 500,00 Indirizzo BIOTRANSFER UNIT SUITE 3-32 BIOL T12 Cork Mostra sulla mappa Regione Ireland Eastern and Midland Dublin Tipo di attività Private for-profit entities (excluding Higher or Secondary Education Establishments) Contatto amministrativo Dmitri Papkovsky (Prof.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato RIJKSUNIVERSITEIT GRONINGEN Paesi Bassi Contributo UE € 1 191 000,00 Indirizzo Broerstraat 5 9712CP Groningen Mostra sulla mappa Regione Noord-Nederland Groningen Overig Groningen Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Dick Veldhuis (Dr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato
