Obiettivo "Oncologists still rely heavily on biological characterisation of tumours and a limited number of biomarkers which have demonstrated clinical utility. Routine cancer diagnostic tools may not be always sensitive enough and may only detect proteins at levels corresponding to an advanced stage of the disease. Recently, new genomic and proteomic molecular tools (molecular signatures) are being employed which include genetic and epigenetic signatures, changes in gene expression, protein profiles and post-translational modification of proteins. Such advanced diagnostic tools are not always readily adapted to clinical cancer screening due to their complexity, costs and the requirement for highly-qualified operators. Novel bioanalytical methodologies for detection of specific biomarkers/ biomolecules, based on nanostructured electronic sensors (rapid, sensitive devices capable of miniaturisation and deployment on site or in small clinics), fulfill the necessary requirements and have the potential to compliment time- and labour consuming clinical analysers used in medical laboratories currently. The primary objective of this proposal, therefore, is to gather together an international and interdisciplinary consortium of ten research teams from EU Member States, Third (including ENP) countries with EU agreements on S&T, in order to share and jointly exploit knowledge and expertise in the development of micro/nanosensors as tools in early cancer diagnosis. A key scientific target is the realisation of intelligent electronic devices which respond to biomolecules such as formaldehyde, amines, metal ions, saccharides, activities of amine oxidases, arginase and glutathione-S-transferase. This will entail design, development and characterisation of nano-scale transducers suitable for testing in clinical samples." Campo scientifico scienze naturaliscienze chimichechimica organicaaldeidiscienze naturaliscienze biologichebiochimicabiomolecoleproteineingegneria e tecnologiaingegneria elettrica, ingegneria elettronica, ingegneria informaticaingegneria elettronicasensoriscienze mediche e della salutemedicina clinicaoncologiascienze naturaliscienze chimichechimica organicaammine Programma(i) FP7-PEOPLE - Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Argomento(i) FP7-PEOPLE-2012-IRSES - Marie Curie Action "International Research Staff Exchange Scheme" Invito a presentare proposte FP7-PEOPLE-2012-IRSES Vedi altri progetti per questo bando Meccanismo di finanziamento MC-IRSES - International research staff exchange scheme (IRSES) Coordinatore INSTITUTE OF TECHNOLOGY TALLAGHT Indirizzo Old blessington road 24 Tallaght dublin 24 Irlanda Mostra sulla mappa Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Eithne Dempsey (Prof.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Contributo UE Nessun dato Partecipanti (5) Classifica in ordine alfabetico Classifica per Contributo UE Espandi tutto Riduci tutto UNIVERSITATEA DIN BUCURESTI Romania Contributo UE € 117 000,00 Indirizzo Soseaua panduri 90 050663 Bucuresti Mostra sulla mappa Regione Macroregiunea Trei Bucureşti-Ilfov Bucureşti Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Camelia Bala (Prof.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Altri finanziamenti Nessun dato UNIVERSITAT ROVIRA I VIRGILI Spagna Contributo UE € 87 000,00 Indirizzo Carrer de escorxador 43003 Tarragona Mostra sulla mappa Regione Este Cataluña Tarragona Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Rosa Solà I Alberich (Dr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Altri finanziamenti Nessun dato UNIVERSIDADE DE COIMBRA Portogallo Contributo UE € 87 700,00 Indirizzo Paco das escolas 3004-531 Coimbra Mostra sulla mappa Regione Continente Centro (PT) Região de Coimbra Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Sergio Vicente (Mr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Altri finanziamenti Nessun dato Linköping University Svezia Contributo UE € 108 400,00 Indirizzo Campus valla 581 83 Linköping Mostra sulla mappa Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Anthony P.F. Turner (Prof.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Altri finanziamenti Nessun dato UNIVERSITE LYON 1 CLAUDE BERNARD Francia Contributo UE € 98 900,00 Indirizzo Boulevard du 11 novembre 1918 num43 69622 Villeurbanne cedex Mostra sulla mappa Regione Auvergne-Rhône-Alpes Rhône-Alpes Rhône Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Javier Olaiz (Dr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Altri finanziamenti Nessun dato
