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Establishing the Hungarian Center of Excellence for Molecular Medicine in partnership with EMBL

Publikacje

Detection and Functional Evaluation of the P2X7 Receptor in hiPSC Derived Neurons and Microglia-Like Cells. Front Mol Neurosci

Autorzy: Francistiová L, Vörös K, Lovász Z, Dinnyés A, Kobolák J.
Opublikowane w: Frontiers in molecular neuroscience, 2022, ISSN 1662-5099
Wydawca: Frontiers Research Foundation
DOI: 10.3389/fnmol.2021.793769

Regulation of Orai channels by intracellular pH: one step closer to understand CRAC channel biology? J Physiol.

Autorzy: Maléth J.
Opublikowane w: Journal of Physiology, 2022, ISSN 1469-7793
Wydawca: Wiley-Blackwell Publishing Ltd
DOI: 10.1113/jp282680

Sierra RO, Pedraza LK, Barcsai L, Pejin A, Li Q, Kozák G, Takeuchi Y, Nagy AJ, Lőrincz ML, Devinsky O, Buzsáki G, Berényi A.

Autorzy: Closed-loop brain stimulation augments fear extinction in male rats. Nat Commun.
Opublikowane w: Nature Communications, 2023, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-023-39546-7

Phenotypic plasticity of melanocytes derived from human adult skin

Autorzy: Dániel László Vidács, Zoltán Veréb, Renáta Bozó, Lili Borbála Flink, Hilda Polyánka, István Balázs Németh, Szilárd Póliska, Benjamin Tamás Papp, Máté Manczinger, Róbert Gáspár, Seyedmohsen Mirdamadi, Lajos Kemény, Zsuzsanna Bata‐Csörgő
Opublikowane w: Pigment Cell & Melanoma Research, 2021, ISSN 1755-1471
Wydawca: Basil Blackwell
DOI: 10.1111/pcmr.13012

Next-Generation Sequencing-Based Genomic Profiling of Children with Acute Myeloid Leukemia.

Autorzy: Krizsán S, Péterffy B, Egyed B, Nagy T, Sebestyén E, Hegyi LL, Jakab Z, Erdélyi DJ, Müller J, Péter G, Csanádi K, Kállay K, Kriván G, Barna G, Bedics G, Haltrich I, Ottóffy G, Csernus K, Vojcek Á, Tiszlavicz LG, Gábor KM, Kelemen Á, Hauser P, Gaál Z, Szegedi I, Ujfalusi A, Kajtár B, Kiss C, Matolcsy A, Tímár B, Kovács G, Alpár D, Bödör C.
Opublikowane w: Journal of Molecular Diagnostics, 2023, ISSN 1525-1578
Wydawca: American Society for Investigative Pathology
DOI: 10.1016/j.jmoldx.2023.04.004

Herpes Simplex Virus Infection Alters the Immunological Properties of Adipose-Tissue-Derived Mesenchymal-Stem Cells.

Autorzy: Kun-Varga A, Gubán B, Miklós V, Parvaneh S, Guba M, Szűcs D, Monostori T, Varga J, Varga Á, Rázga Z, Bata-Csörgő Z, Kemény L, Megyeri K, Veréb Z.
Opublikowane w: International Journal of Molecular Sciences, 2023, ISSN 1422-0067
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms241511989

Candida albicans Enhances the Progression of Oral Squamous Cell Carcinoma In Vitro and In Vivo.

Autorzy: Vadovics M, Ho J, Igaz N, Alföldi R, Rakk D, Veres É, Szücs B, Horváth M, Tóth R, Szücs A, Csibi A, Horváth P, Tiszlavicz L, Vágvölgyi C, Nosanchuk JD, Szekeres A, Kiricsi M, Henley-Smith R, Moyes DL, Thavaraj S, Brown R, Puskás LG, Naglik JR, Gácser A.
Opublikowane w: mBio, 2022, ISSN 2150-7511
Wydawca: American Society for Microbiology
DOI: 10.1128/mbio.03144-21

Different prognostic impact of recurrent gene mutations in chronic lymphocytic leukemia depending on IGHV gene somatic hypermutation status: a study by ERIC in HARMONY.

Autorzy: Mansouri L, Thorvaldsdottir B, Sutton LA, Karakatsoulis G, Meggendorfer M, Parker H, Nadeu F, Brieghel C, Laidou S, Moia R, Rossi D, Catherwood M, Kotaskova J, Delgado J, Rodríguez-Vicente AE, Benito R, Rigolin GM, Bonfiglio S, Scarfo L, Mattsson M, Davis Z, Gogia A, Rani L, Baliakas P, Foroughi-Asl H, Jylhä C, Skaftason A, Rapado I, Miras F, Martinez-Lopez J, de la Serna J, Rivas JMH, Thornton
Opublikowane w: Leukemia, 2022, ISSN 0887-6924
Wydawca: Nature Publishing Group
DOI: 10.1038/s41375-022-01802-y

Characterization and functional analysis of zinc trafficking in the human fungal pathogen Candida parapsilosis.

Autorzy: Takács T, Németh MT, Bohner F, Vágvölgyi C, Jankovics F, Wilson D, Gácser A.
Opublikowane w: Open biology, 2022, ISSN 2046-2441
Wydawca: Royal Society Publishing
DOI: 10.1098/rsob.220077

Molecular pathology of the R117H cystic fibrosis mutation is explained by loss of a hydrogen bond.

Autorzy: Simon MA, Csanády L.
Opublikowane w: eLife Sciences Publications, 2019, ISSN 2050-084X
Wydawca: eLife Sciences Publications
DOI: 10.7554/elife.74693

Influence of cardiometabolic comorbidities on myocardial function, infarction, and CARDIOPROTECTION: Role of cardiac redox signaling

Autorzy: Ioanna Andreadou, Andreas Daiber, Gary F. Baxter, Maria.Felice Brizzi, Fabio di Lisa, Nina Kaludercic, Antigone Lazou, Zoltán.V. Varga, Coert Zuurbier, Rainer Schulz, Péter Ferdinandy
Opublikowane w: Free Radical Biology and Medicine, 2021, ISSN 0891-5849
Wydawca: Elsevier BV
DOI: 10.1016/j.freeradbiomed.2021.02.012

Genes with epigenetic alterations in human pancreatic islets impact mitochondrial function, insulin secretion, and type 2 diabetes.

Autorzy: Rönn T, Ofori JK, Perfilyev A, Hamilton A, Pircs K, Eichelmann F, Garcia-Calzon S, Karagiannopoulos A, Stenlund H, Wendt A, Volkov P, Schulze MB, Mulder H, Eliasson L, Ruhrmann S, Bacos K, Ling C.
Opublikowane w: Nature Communications, 2023, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-023-43719-9

Antineoplastic drugs inducing cardiac and vascular toxicity - An update.

Autorzy: Barachini S, Ghelardoni S, Varga ZV, Mehanna RA, Montt-Guevara MM, Ferdinandy P, Madonna R.
Opublikowane w: Vascular Pharmacology, 2023, ISSN 1879-3649
Wydawca: Elsevier
DOI: 10.1016/j.vph.2023.107223

The genomic landscape of teenage and young adult T‐cell acute lymphoblastic leukemia

Autorzy: Marcela B. Mansur, Caroline L. Furness, Sirintra Nakjang, Amir Enshaei, Donat Alpar, Sue M. Colman, Lynne Minto, Julie Irving, Beth V. Poole, Elda P. Noronha, Suvi Savola, Sameena Iqbal, John Gribben, Maria S. Pombo‐de‐Oliveira, Tony M. Ford, Mel F. Greaves, Frederik W. Delft
Opublikowane w: Cancer Medicine, 2021, ISSN 2045-7634
Wydawca: John Wiley and Sons Ltd
DOI: 10.1002/cam4.4024

Liquid biopsy-based monitoring of residual disease in multiple myeloma by analysis of the rearranged immunoglobulin genes-A feasibility study.

Autorzy: Marx A, Osváth M, Szikora B, Pipek O, Csabai I, Nagy Á, Bödör C, Matula Z, Nagy G, Bors A, Uher F, Mikala G, Vályi-Nagy I, Kacskovics I.
Opublikowane w: PLoS One, 2023, ISSN 1932-6203
Wydawca: Public Library of Science
DOI: 10.1371/journal.pone.0285696

In Vitro Determination of Inhibitory Effects of Humic Substances Complexing Zn and Se on SARS-CoV-2 Virus Replication. Foods.

Autorzy: Hajdrik P, Pályi B, Kis Z, Kovács N, Veres DS, Szigeti K, Budán F, Hegedüs I, Kovács T, Bergmann R, Máthé D.
Opublikowane w: Foods, 2022, ISSN 2304-8158
Wydawca: MDPI Multidisciplinary Digital Publishing Institute
DOI: 10.3390/foods11050694

Synergism of red blood cells and tranexamic acid in the inhibition of fibrinolysis.

Autorzy: Raska A, Kálmán K, Egri B, Csikós P, Beinrohr L, Szabó L, Tenekedjiev K, Nikolova N, Longstaff C, Roberts I, Kolev K, Wohner N.
Opublikowane w: Journal of Thrombosis and Haemostasis, 2023, ISSN 1538-7836
Wydawca: Wiley-Blackwell Publishing Ltd
DOI: 10.1016/j.jtha.2023.11.009

TRAF3 and NBR1 both influence the effect of the disease‐causing CYLD(Arg936X) mutation on NF‐κB activity

Autorzy: Judit Danis, Evelyn Kelemen, Neil Rajan, Nikoletta Nagy, Márta Széll, Éva Ádám
Opublikowane w: Experimental Dermatology, 2021, ISSN 0906-6705
Wydawca: Blackwell Publishing Inc.
DOI: 10.1111/exd.14365

Capturing time-dependent activation of genes and stress-response pathways using transcriptomics in iPSC-derived renal proximal tubule cells.

Autorzy: Jennings P, Carta G, Singh P, da Costa Pereira D, Feher A, Dinnyes A, Exner TE, Wilmes A.
Opublikowane w: Cell Biology and Toxicology, 2022, ISSN 0742-2091
Wydawca: Kluwer Academic Publishers
DOI: 10.1007/s10565-022-09783-5

Blue flash sheds light on the roles of individual phosphoserines in CFTR channel activation.

Autorzy: Csanády L.
Opublikowane w: Journal of General Physiology, 2023, ISSN 0022-1295
Wydawca: Rockefeller University Press
DOI: 10.1085/jgp.202313336

Cellular and Molecular Effects of SARS-CoV-2 Linking Lung Infection to the Brain

Autorzy: Linda Francistiová, Adrián Klepe, Géza Curley, Károly Gulya, András Dinnyés, Kata Filkor
Opublikowane w: Frontiers in Immunology, Numer 12, 2021, ISSN 1664-3224
Wydawca: Frontiers Media S.A.
DOI: 10.3389/fimmu.2021.730088

Extracellular Vesicle-Mediated Metastasis Suppressors NME1 and NME2 Modify Lipid Metabolism in Fibroblasts.

Autorzy: Mátyási B, Petővári G, Dankó T, Butz H, Likó I, Lőw P, Petit I, Bittar R, Bonnefont-Rousselot D, Farkas Z, Szeniczey T, Molnár K, Pálóczi K, Buzás EI, Boissan M, Sebestyén A, Takács-Vellai K.
Opublikowane w: Cancers, 2022, ISSN 2072-6694
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers14163913

Application of Lacunarity for Quantification of Single Molecule Localization Microscopy Images.

Autorzy: Kovács BBH, Varga D, Sebők D, Majoros H, Polanek R, Pankotai T, Hideghéty K, Kukovecz Á, Erdélyi M.
Opublikowane w: Cells, Numer 20734409, 2022, ISSN 2073-4409
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cells11193105

AIM2-driven inflammasome activation in heart failure

Autorzy: Zsófia Onódi, Mihály Ruppert, Dániel Kucsera, Alex Ali Sayour, Viktória E Tóth, Gábor Koncsos, Julianna Novák, Gábor B Brenner, András Makkos, Tamás Baranyai, Zoltán Giricz, Anikó Görbe, Przemyslaw Leszek, Mariann Gyöngyösi, Iván G Horváth, Rainer Schulz, Béla Merkely, Péter Ferdinandy, Tamás Radovits, Zoltán V Varga
Opublikowane w: Cardiovascular Research, 2021, ISSN 0008-6363
Wydawca: Elsevier BV
DOI: 10.1093/cvr/cvab202

Suboptimal global transcriptional response increases the harmful effects of loss-of-function mutations

Autorzy: Károly Kovács, Zoltán Farkas, Djordje Bajić, Dorottya Kalapis, Andreea Daraba, Karola Almási, Bálint Kintses, Zoltán Bódi, Richard A Notebaart, Juan F Poyatos, Patrick Kemmeren, Frank C P Holstege, Csaba Pál, Balázs Papp
Opublikowane w: Molecular Biology and Evolution, 2020, ISSN 0737-4038
Wydawca: Oxford University Press
DOI: 10.1093/molbev/msaa280

Adenosine Promotes Human Hair Growth and Inhibits Catagen Transition In Vitro: Role of the Outer Root Sheath Keratinocytes

Autorzy: Erika Lisztes, Balázs István Tóth, Marta Bertolini, Imre Lőrinc Szabó, Nóra Zákány, Attila Oláh, Attila Gábor Szöllősi, Ralf Paus, Tamás Bíró
Opublikowane w: Journal of Investigative Dermatology, Numer 140/5, 2020, Strona(/y) 1085-1088.e6, ISSN 0022-202X
Wydawca: Blackwell Publishing Inc.
DOI: 10.1016/j.jid.2019.08.456

The Phytocannabinoid (–)-Cannabidiol Operates as a Complex, Differential Modulator of Human Hair Growth: Anti-Inflammatory Submicromolar versus Hair Growth Inhibitory Micromolar Effects

Autorzy: Imre L. Szabó, Erika Lisztes, Gabriella Béke, Kinga Fanni Tóth, Ralf Paus, Attila Oláh, Tamás Bíró
Opublikowane w: Journal of Investigative Dermatology, Numer 140/2, 2019, ISSN 0022-202X
Wydawca: Blackwell Publishing Inc.
DOI: 10.1016/j.jid.2019.07.690

Endoplasmin Is a Hypoxia-Inducible Endoplasmic Reticulum-Derived Cargo of Extracellular Vesicles Released by Cardiac Cell Lines.

Autorzy: Koncz A, Turiák L, Németh K, Lenzinger D, Bárkai T, Lőrincz P, Zelenyánszki H, Vukman KV, Buzás EI, Visnovitz T.
Opublikowane w: Membranes, 2023, ISSN 2077-0375
Wydawca: Molecular Diversity Preservation International
DOI: 10.3390/membranes13040431

Nanotheranostic agents for neurodegenerative diseases

Autorzy: Parasuraman Padmanabhan, Mathangi Palanivel, Ajay Kumar, Domokos Máthé, George K. Radda, Kah-Leong Lim, Balázs Gulyás
Opublikowane w: Emerging Topics in Life Sciences, Numer 4/6, 2020, Strona(/y) 645-675, ISSN 2397-8554
Wydawca: Portland Press
DOI: 10.1042/etls20190141

Cyclooxygenase-2 Modulates Glycosaminoglycan Production in the Skin During Salt Overload

Autorzy: Róbert Agócs, Domonkos Pap, Dániel Sugár, Gábor Tóth, Lilla Turiák, Zoltán Veréb, Lajos Kemény, Tivadar Tulassay, Ádám Vannay, Attila J. Szabó
Opublikowane w: Frontiers in Physiology, Numer 11, 2020, ISSN 1664-042X
Wydawca: Frontiers Research Foundation
DOI: 10.3389/fphys.2020.561722

Coordinated Cut and Bypass: Replication of Interstrand Crosslink-Containing DNA

Autorzy: Qiuzhen Li, Kata Dudás, Gabriella Tick, Lajos Haracska
Opublikowane w: Frontiers in Cell and Developmental Biology, Numer 9, 2021, ISSN 2296-634X
Wydawca: Frontiers Media S.A.
DOI: 10.3389/fcell.2021.699966

Manifestation of Triploid Heterosis in the Root System after Crossing Diploid and Autotetraploid Energy Willow Plants.

Autorzy: Dudits D, Cseri A, Török K, Vankova R, Dobrev PI, Sass L, Steinbach G, Kelemen-Valkony I, Zombori Z, Ferenc G, Ayaydin F.
Opublikowane w: Genes, 2023, ISSN 2073-4425
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/genes14101929

Cardioprotective efficacy of limb remote ischemic preconditioning in rats: discrepancy between meta-analysis and a three-centre in vivo study.

Autorzy: Sayour NV, Brenner GB, Makkos A, Kiss B, Kovácsházi C, Gergely TG, Aukrust SG, Tian H, Zenkl V, Gömöri K, Szabados T, Bencsik P, Heinen A, Schulz R, Baxter GF, Zuurbier CJ, Vokó Z, Ferdinandy P, Giricz Z.
Opublikowane w: Caridovascular Research, 2023, ISSN 0008-6363
Wydawca: Elsevier BV
DOI: 10.1093/cvr/cvad024

IBCL-222 Parallel Testing of Liquid Biopsy (ctDNA) and Tissue Biopsy Samples Yields Higher Frequency of EZH2 Mutations in Follicular Lymphoma.

Autorzy: Nagy Á, Bátai B, Gróf S, Kiss L, Balogh A, Mikala G, Király PA, Jóna Á, Demeter J, Masszi T, Masszi A, Schneider T, Bödör C.
Opublikowane w: Clin Lymphoma Myeloma Leuk., Numer 21522650, 2022, ISSN 2152-2650
Wydawca: Cancer Media Group
DOI: 10.1016/s2152-2650(22)01553-1

BC-miR: Monitoring Breast Cancer-Related miRNA Profile in Blood Sera-A Prosperous Approach for Tumor Detection.

Autorzy: Borsos BN, Páhi ZG, Ujfaludi Z, Sükösd F, Nikolényi A, Bankó S, Pankotai-Bodó G, Oláh-Németh O, Pankotai T.
Opublikowane w: Cells, 2022, ISSN 2073-4409
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cells11172721

Extracellular Vesicle-Based Communication May Contribute to the Co-Evolution of Cancer Stem Cells and Cancer-Associated Fibroblasts in Anti-Cancer Therapy

Autorzy: Gábor Valcz, Edit I. Buzás, Anna Sebestyén, Tibor Krenács, Zoltán Szállási, Péter Igaz, Béla Molnár
Opublikowane w: Cancers, Numer 12/8, 2020, Strona(/y) 2324, ISSN 2072-6694
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers12082324

The Medial Septum as a Potential Target for Treating Brain Disorders Associated With Oscillopathies

Autorzy: Yuichi Takeuchi, Anett J. Nagy, Lívia Barcsai, Qun Li, Masahiro Ohsawa, Kenji Mizuseki, Antal Berényi
Opublikowane w: Frontiers in Neural Circuits, Numer 15, 2021, ISSN 1662-5110
Wydawca: Frontiers Research Foundation
DOI: 10.3389/fncir.2021.701080

Opportunities and challenges in studying the extracellular vesicle corona.

Autorzy: Buzas EI.
Opublikowane w: Nature Cell Biology, 2022, ISSN 1465-7392
Wydawca: Nature Publishing Group
DOI: 10.1038/s41556-022-00983-z

Genome-wide association study identifies susceptibility loci for acute myeloid leukemia

Autorzy: Wei-Yu Lin, Sarah E. Fordham, Eric Hungate, Nicola J. Sunter, Claire Elstob, Yaobo Xu, Catherine Park, Anne Quante, Konstantin Strauch, Christian Gieger, Andrew Skol, Thahira Rahman, Lara Sucheston-Campbell, Junke Wang, Theresa Hahn, Alyssa I. Clay-Gilmour, Gail L. Jones, Helen J. Marr, Graham H. Jackson, Tobias Menne, Mathew Collin, Adam Ivey, Robert K. Hills, Alan K. Burnett, Nigel H. Russell, J
Opublikowane w: Nature Communications, Numer 12/1, 2021, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-021-26551-x

Two Decades of Evolution of Our Understanding of the Transient Receptor Potential Melastatin 2 (TRPM2) Cation Channel

Autorzy: Andras Szollosi
Opublikowane w: Life, Numer 11/5, 2021, Strona(/y) 397, ISSN 2075-1729
Wydawca: MDPI Multidisciplinary Digital Publishing Institute
DOI: 10.3390/life11050397

Biocompatible poly(ethylene succinate) polyester with molecular weight dependent drug release properties.

Autorzy: Abdelghafour MM, Orbán Á, Deák Á, Lamch Ł, Frank É, Nagy R, Ziegenheim S, Sipos P, Farkas E, Bari F, Janovák L.
Opublikowane w: Biomaterials, 2022, ISSN 0142-9612
Wydawca: Pergamon Press Ltd.
DOI: 10.1016/j.ijpharm.2022.121653

Temporally Targeted Interactions With Pathologic Oscillations as Therapeutical Targets in Epilepsy and Beyond.

Autorzy: Földi T, Lőrincz ML and Berényi
Opublikowane w: Frontiers in Neural Circuits, 2021, ISSN 1662-5110
Wydawca: Frontiers Research Foundation
DOI: 10.3389/fncir.2021.784085

Molecular imaging of bacterial outer membrane vesicles based on bacterial surface display.

Autorzy: Kövesdi D, Bősze S, Szabó I, Felföldi T, Oszwald E, Padmanabhan P, Gulyás BZ, Hamdani N, Máthé D, Varga Z, Szigeti K.
Opublikowane w: Scientific Reports, 2023, ISSN 2045-2322
Wydawca: Nature Publishing Group
DOI: 10.1038/s41598-023-45628-9

Multiple Layers of Complexity in O-Glycosylation Illustrated With the Urinary Glycoproteome.

Autorzy: Pap A, Kiraly IE, Medzihradszky KF, Darula Z.
Opublikowane w: Molecular and Cellular Proteomics, 2022, ISSN 1535-9476
Wydawca: American Society for Biochemistry and Molecular Biology Inc.
DOI: 10.1016/j.mcpro.2022.100439

Intracellular Ca2+ Signalling in the Pathogenesis of Acute Pancreatitis: Recent Advances and Translational Perspectives

Autorzy: Petra Pallagi, Tamara Madácsy, Árpád Varga, József Maléth
Opublikowane w: International Journal of Molecular Sciences, Numer 21/11, 2020, Strona(/y) 4005, ISSN 1422-0067
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21114005

MiR-128-3p as blood based liquid biopsy biomarker in childhood acute lymphoblastic leukemia.

Autorzy: Rzepiel A, Horváth A, Kutszegi N, Gézsi A, Sági JC, Almási L, Egyed B, Lőrincz P, Visnovitz T, Kovács GT, Szalai C, Semsei ÁF, Erdélyi DJ.
Opublikowane w: Molecular and Cellular Probes, 2023, ISSN 0890-8508
Wydawca: Academic Press
DOI: 10.1016/j.mcp.2023.101893

Dry storage of mammalian spermatozoa and cells: state-of-the-art and possible future directions

Autorzy: P. Loi, D. A. Anzalone, L. Palazzese, A. Dinnyés, J. Saragusty, M. Czernik
Opublikowane w: Reproduction, Fertility and Development, Numer 33/2, 2021, Strona(/y) 82, ISSN 1031-3613
Wydawca: Commonwealth Scientific and Industrial Research Organization Publishing
DOI: 10.1071/rd20264

TFLink: an integrated gateway to access transcription factor-target gene interactions for multiple species.

Autorzy: Liska O, Bohár B, Hidas A, Korcsmáros T, Papp B, Fazekas D, Ari E.
Opublikowane w: Database, Numer 17580463, 2022, ISSN 1758-0463
Wydawca: Oxford University Press
DOI: 10.1093/database/baac083

Tumour Necrosis Factor Alpha-induced Protein 3 Negatively Regulates Cutibacterium acnes-induced Innate Immune Events in Epidermal Keratinocytes

Autorzy: Lilla Erdei, Beáta Szilvia Bolla, Renáta Bozó, Gábor Tax, Edit Urbán, Katalin Burián, Lajos Kemény, Kornélia Szabó
Opublikowane w: Acta Dermato-Venereologica, 2021, ISSN 0001-5555
Wydawca: Taylor & Francis
DOI: 10.2340/00015555-3707

Molecular characterization of immune checkpoint inhibitor-induced cardiotoxicity reveals IL-17A as a driver of cardiac dysfunction after anti-PD-1 treatment.

Autorzy: Gergely TG, Kucsera D, Tóth VE, Kovács T, Sayour NV, Drobni ZD, Ruppert M, Petrovich B, Ágg B, Onódi Z, Fekete N, Pállinger É, Buzás EI, Yousif LI, Meijers WC, Radovits T, Merkely B, Ferdinandy P, Varga ZV.
Opublikowane w: British Journal of Pharmacology, Numer 00071188, 2022, ISSN 0007-1188
Wydawca: Wiley-Blackwell
DOI: 10.1111/bph.15984

Two-year event-free survival prediction in DLBCL patients based on in vivo radiomics and clinical parameters,

Autorzy: Zsombor Ritter, Laszlo Papp, Katalin Zámbó, Zoltan Tóth, Dániel Dezso, Dániel Sándor Veres, Domokos Máthé, Ferenc Budán, Éva Karádi, Anett Balikó, László Pajor, Árpád Szomor, Erzsébet Schmidt, Hussain Alizadeh
Opublikowane w: Hematologic Malignancies, 2022, ISSN 2234-943X
Wydawca: Frontiers Media S. A.
DOI: 10.3389/fonc.2022.820136

Ca2+/calmodulin-dependent protein kinase II and protein kinase G oxidation contributes to impaired sarcomeric proteins in hypertrophy model.

Autorzy: Gömöri K, Herwig M, Budde H, Hassoun R, Mostafi N, Zhazykbayeva S, Sieme M, Modi S, Szabados T, Pipis J, Farkas-Morvay N, Leprán I, Ágoston G, Baczkó I, Kovács Á, Mügge A, Ferdinandy P, Görbe A, Bencsik P, Hamdani N.
Opublikowane w: ESC Heart Fail, 2022, ISSN 2055-5822
Wydawca: The Heart Failure Association of the European Society of Cardiology
DOI: 10.1002/ehf2.13973

Systematic transcriptomic and phenotypic characterization of human and murine cardiac myocyte cell lines and primary cardiomyocytes reveals serious limitations and low resemblances to adult cardiac phenotype. J Mol Cell Cardiol.

Autorzy: Onódi Z, Visnovitz T, Kiss B, Hambalkó S, Koncz A, Ágg B, Váradi B, Tóth VÉ, Nagy RN, Gergely TG, Gergő D, Makkos A, Pelyhe C, Varga N, Reé D, Apáti Á, Leszek P, Kovács T, Nagy N, Ferdinandy P, Buzás EI, Görbe A, Giricz Z, Varga ZV.
Opublikowane w: Journal of Molecular and Cellular Cardiology, 2021, ISSN 0022-2828
Wydawca: Academic Press
DOI: 10.1016/j.yjmcc.2021.12.007

Could basement membrane alterations, resembling micro‐wounds at the dermo‐epidermal junction in psoriatic non‐lesional skin, make the skin susceptible to lesion formation?

Autorzy: Renáta Bozó, Lili Borbála Flink, Nóra Belső, Barbara Gubán, Márta Széll, Lajos Kemény, Zsuzsanna Bata‐Csörgő
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Shared extracellular vesicle miRNA profiles of matched ductal pancreatic adenocarcinoma organoids and blood plasma samples show the power of organoid technology

Autorzy: Anikó Zeöld, Gyöngyvér Orsolya Sándor, Anna Kiss, András Áron Soós, Tamás Tölgyes, Attila Bursics, Ákos Szűcs, László Harsányi, Ágnes Kittel, András Gézsi, Edit I. Buzás, Zoltán Wiener
Opublikowane w: Cellular and Molecular Life Sciences, 2020, ISSN 1420-682X
Wydawca: Birkhauser Verlag
DOI: 10.1007/s00018-020-03703-8

The IV International Symposium on Fungal Stress and the XIII International Fungal Biology Conference.

Autorzy: Alder-Rangel A, Bailão AM, Herrera-Estrella A, Rangel AEA, Gácser A, Gasch AP, Campos CBL, Peters C, Camelim F, Verde F, Gadd GM, Braus G, Eisermann I, Quinn J, Latgé JP, Aguirre J, Bennett JW, Heitman J, Nosanchuk JD, Partida-Martínez LP, Bassilana M, Acheampong MA, Riquelme M, Feldbrügge M, Keller NP, Keyhani NO, Gunde-Cimerman N, Nascimento R, Arkowitz RA, Mouriño-Pérez RR, Naz SA, Avery
Opublikowane w: Fungal Biology, 2023, ISSN 1096-0937
Wydawca: Academic Press Inc.
DOI: 10.1016/j.funbio.2023.04.006

Estimating the true stability of the prehydrolytic outward-facing state in an ABC protein.

Autorzy: Simon MA, Iordanov I, Szollosi A, Csanády L.
Opublikowane w: eLife, 2023, ISSN 2050-084X
Wydawca: eLife Sciences Publications
DOI: 10.7554/elife.90736

Merkel K, Szöllősi D, Horváth I, Jezsó B, Baranyai Z, Szigeti K, Varga Z, Hegedüs I, Padmanabhan P, Gulyás B, Bergmann R, Máthé D.

Autorzy: Radiolabeling of Platelets with 99mTc-HYNIC-Duramycin for In Vivo Imaging Studies.
Opublikowane w: Internaitonal Journal of Molecular Sciences, 2023, ISSN 1422-0067
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms242317119

The Rad5 helicase and RING domains contribute to genome stability through their independent catalytic activities.

Autorzy: Toth R, Balogh D, Pinter L, Jaksa G, Szeplaki B, Graf A, Gyorfy Z, Zs Enyedi M, Kiss E, Haracska L, Unk I.
Opublikowane w: Journal of molecular biology, 2022, ISSN 0022-2836
Wydawca: Academic Press
DOI: 10.1016/j.jmb.2021.167437

IL-1β neutralization prevents diastolic dysfunction development, but lacks hepatoprotective effect in an aged mouse model of NASH.

Autorzy: Kucsera D, Tóth VE, Sayour NV, Kovács T, Gergely TG, Ruppert M, Radovits T, Fábián A, Kovács A, Merkely B, Ferdinandy P, Varga ZV.
Opublikowane w: Scientific Reports, 2023, ISSN 2045-2322
Wydawca: Nature Publishing Group
DOI: 10.1038/s41598-022-26896-3

Characterization of Neurons Expressing the Novel Analgesic Drug Target Somatostatin Receptor 4 in Mouse and Human Brains

Autorzy: Angéla Kecskés, Krisztina Pohóczky, Miklós Kecskés, Zoltán V. Varga, Viktória Kormos, Éva Szőke, Nóra Henn-Mike, Máté Fehér, József Kun, Attila Gyenesei, Éva Renner, Miklós Palkovits, Péter Ferdinandy, István M. Ábrahám, Balázs Gaszner, Zsuzsanna Helyes
Opublikowane w: International Journal of Molecular Sciences, Numer 21/20, 2020, Strona(/y) 7788, ISSN 1422-0067
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21207788

Interdisciplinary Analyses of Bronze Age Communities from Western Hungary Reveal Complex Population Histories.

Autorzy: Gerber D, Szeifert B, Székely O, Egyed B, Gyuris B, Giblin JI, Horváth A, Köhler K, Kulcsár G, Kustár Á, Major I, Molnár M, Palcsu L, Szeverényi V, Fábián S, Mende BG, Bondár M, Ari E, Kiss V, Szécsényi-Nagy A.
Opublikowane w: Molecular Biology and Evolution, 2023, ISSN 1537-1719
Wydawca: Oxford University Press
DOI: 10.1093/molbev/msad182

IDENTIFICATION OF NEGATIVE REGULATORS OF THE CUTIBACTERIUM ACNES-INDUCED INNATE IMMUNE ACTIVATION IN HUMAN EPIDERMAL KERATINOCYTES

Autorzy: Lilla Erdei
Opublikowane w: 2020
Wydawca: -

Immune-inflammatory targets in chronic heart failure: inflammasomes and the endocannabinoid system

Autorzy: Zsófia Gulyás-Onódi
Opublikowane w: 2022
Wydawca: Semmelweis University

Értekezés címe: Az in vivo fehérjeaggregáció útvonalait befolyásoló tényezők vizsgálata Escherichia coliban

Autorzy: Györkei Ádám
Opublikowane w: 2022
Wydawca: -

Discovery of small-molecule inhibitors of Rad6 function and the Rad6-Rad18 interaction

Autorzy: Sharma Gaurav
Opublikowane w: 2023
Wydawca: -

A CFTR anioncsatorna extracelluláris régiójának a csatorna működésére gyakorolt hatása

Autorzy: Simon Márton András
Opublikowane w: 2023
Wydawca: -

Application of Circulating Tumor DNA Analysis for the Detection of EZH2 Mutations in Follicular Lymphoma

Autorzy: Nagy Ákos
Opublikowane w: 2023
Wydawca: -

BRCA1/2 patogén és ismeretlen klinikai szignifikanciájú variánsok azonosítása és vizsgálati lehetőségei

Autorzy: Gráf Alexandra
Opublikowane w: 2022
Wydawca: -

The study of the membrane microdomain localization of the prion-family proteins, prion and Shadoo and their interaction with calnexin

Autorzy: Divya Teja Dondapati
Opublikowane w: 2022
Wydawca: University of Szeged

Hipertermia-okozta stresszválasz molekuláris mechanizmusai emlős sejtekben

Autorzy: Tiszlavicz Ádám
Opublikowane w: 2022
Wydawca: -

Compensatory evolution as a driver of morphological novelties

Autorzy: Sarkadi Zsuzsa
Opublikowane w: 2022
Wydawca: -

Antitumor effects of modulated electro-hyperthermia in 4T1 triple-negative breast cancer models

Autorzy: Danics Lea Orsolya
Opublikowane w: 2021
Wydawca: -

Controlling cell polarity in human pancreatic organoids significantly improves the resolution of ex vivo physiological modeling

Autorzy: Varga Árpád
Opublikowane w: 2023
Wydawca: -

Epigenetic consequences of in utero exposure to rosuvastatin include altered histone methylation patterns in newborn rat brains

Autorzy: Fábián-Dulka Karolina
Opublikowane w: 2021
Wydawca: University of Szeged

Molecular background of resistance to targeted therapies in chronic lymphocytic

Autorzy: Kotmayer Lili Eszter
Opublikowane w: 2023
Wydawca: -

Potential relevance of altered cartilage oligomeric matrix protein in psoriasis

Autorzy: Renáta Bozó
Opublikowane w: 2020
Wydawca: University of Szeged

Discovery of small-molecule inhibitors of Uba1 and development of step-specific assays for PCNA ubiquitination

Autorzy: Paras Gaur
Opublikowane w: 2020
Wydawca: -

A funkcionális metagenomika módszerének kiterjesztése kórokozó baktériumokra az antibiotikumrezisztencia vizsgálatának céljából

Autorzy: Számel Mónika
Opublikowane w: 2023
Wydawca: -

CFTR deficiency causes PMCA4 dysfunction, intracellular Ca2+ elevation and promotes epithelial cell damage in alcoholic pancreatitis and hepatitis

Autorzy: Tamara Éva Madácsy
Opublikowane w: 2022
Wydawca: University of Szeged

Vasculitides primarily involving the skin

Autorzy: Géza Róbert Nagy
Opublikowane w: 2020
Wydawca: University of Szeged

RAD18-dependent Activation of FAN1 by Ub-PCNA to Rescue DNA Interstrand crosslinks along with TLS Pol η

Autorzy: Qiuzhen Li
Opublikowane w: 2021
Wydawca: -

Bioanalytics, lipidomics and metabolomics application of one- and two-dimensional LC-MS techniques

Autorzy: Tímea Körmöczi
Opublikowane w: 2022
Wydawca: University of Szeged

The effect of Cutibacterium acnes on the barrier properties of in vitro cultured keratinocytes

Autorzy: Beáta Szilvia Bolla
Opublikowane w: 2020
Wydawca: University of Szeged

Szívelégtelenségben ható szerek

Autorzy: Ferdinandy Péter, Varga Zoltán In: Gyires Klára, Fürst Zsuzsanna, Ferdinandy Péter, Pintér Erika, Szilvássy Zoltán, Varró András (szerk.)
Opublikowane w: Farmakológia és klinikai farmakológia: egyetemi tankönyv, Numer p. 10, 2020, Strona(/y) pp. 224-233
Wydawca: Medicina Könyvkiadó Zrt.

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