Pubblicazioni Peer reviewed articles (22) Structural basis of NINJ1-mediated plasma membrane rupture in cell death Autori: Morris Degen, José Carlos Santos, Kristyna Pluhackova, Gonzalo Cebrero, Saray Ramos, Gytis Jankevicius, Ella Hartenian, Undina Guillerm, Stefania A. Mari, Bastian Kohl, Daniel J. Müller, Paul Schanda, Timm Maier, Camilo Perez, Christian Sieben, Petr Broz & Sebastian Hiller Pubblicato in: Nature, Issue 618,, 2023, Page(s) pages 1065–1071, ISSN 0028-0836 Editore: Nature Publishing Group DOI: 10.1038/s41586-023-05991-z Regulation of Lytic and Non-Lytic Functions of Gasdermin Pores Autori: Sebastian Rühl 1 , Petr Broz 2 Pubblicato in: JMB, Issue 00222836, 2022, ISSN 0022-2836 Editore: Academic Press DOI: 10.1016/j.jmb.2021.167246 Beyond inflammasomes: emerging function of gasdermins during apoptosis and NETosis Autori: Kaiwen W Chen, Benjamin Demarco, Petr Broz Pubblicato in: The EMBO Journal, Issue 39/2, 2020, Page(s) -, ISSN 0261-4189 Editore: Nature Publishing Group DOI: 10.15252/embj.2019103397 RIPK1 activates distinct gasdermins in macrophages and neutrophils upon pathogen blockade of innate immune signaling Autori: Chen K.W., Demarco B., Ramos S., Heilig R., Goris M., Grayczyk J.P., Assenmacher C.A., Radaelli E., Joannas L.D., Henao-Mejia J., Tacchini-Cottier F., Brodsky I.E., Broz P. Pubblicato in: PNAS, Issue 10916490, 2021, ISSN 1091-6490 Editore: Proceedings of the National Academy of Sciences of the United States of America DOI: 10.1073/pnas.2101189118 Unconventional protein secretion by gasdermin pores Autori: P Broz Pubblicato in: Seminars in Immunology, Issue 69, 2023, Page(s) 101811, ISSN 1044-5323 Editore: Academic Press DOI: 10.1016/j.smim.2023.101811 NINJ1 induces plasma membrane rupture and release of damage-associated molecular pattern molecules during ferroptosis Autori: Ramos S., Hartenian E., Santos J.C., Walch P., Broz P. Pubblicato in: The EMBO journal, Issue 43, 2024, Page(s) 7, ISSN 0261-4189 Editore: Nature Publishing Group DOI: 10.1038/s44318-024-00055-y Gasdermin D is the only Gasdermin that provides protection against acute Salmonella gut infection in mice Autori: Fattinger S.A., Maurer L., Geiser P., Bernard E.M., Enz U., Ganguillet S., Gül E., Kroon S., Demarco B., Mack V., Furter M., Barthel M., Pelczar P., Shao F., Broz P., Sellin M.E., Hardt W.D. Pubblicato in: PNAS, Issue 120, 2023, Page(s) 48, ISSN 0027-8424 Editore: National Academy of Sciences DOI: 10.1073/pnas.2315503120 Human GBP1 binds LPS to initiate assembly of a caspase-4 activating platform on cytosolic bacteria Autori: Santos, José Carlos; Boucher, Dave; Schneider, Larisa Kapinos; Demarco, Benjamin; Dilucca, Marisa; Shkarina, Kateryna; Heilig, Rosalie; Chen, Kaiwen W.; Lim, Roderick Y. H.; Broz, Petr Pubblicato in: Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020), Issue 11, 2020, Page(s) 1, ISSN 2041-1723 Editore: Nature Publishing Group Selective induction of programmed cell death using synthetic biology tools Autori: Shkarina K., Broz P. Pubblicato in: Seminars in cell & developmental biology, Issue 156, 2024, Page(s) 74-92, ISSN 1084-9521 Editore: Academic Press DOI: 10.1016/j.semcdb.2023.07.012 ESCRT-dependent membrane repair negatively regulates pyroptosis downstream of GSDMD activation Autori: Sebastian Rühl, Kateryna Shkarina, Benjamin Demarco, Rosalie Heilig, José Carlos Santos, Petr Broz Pubblicato in: Science, Issue 362/6417, 2018, Page(s) 956-960, ISSN 0036-8075 Editore: American Association for the Advancement of Science DOI: 10.1126/science.aar7607 Pannexin-1 channels bridge apoptosis to NLRP3 inflammasome activation Autori: Benjamin Demarco, Kaiwen W. Chen, Petr Broz Pubblicato in: Molecular & Cellular Oncology, Issue 6/4, 2019, Page(s) 1610324, ISSN 2372-3556 Editore: Taylor & Francis Online DOI: 10.1080/23723556.2019.1610324 Pannexin‐1 promotes NLRP3 activation during apoptosis but is dispensable for canonical or noncanonical inflammasome activation Autori: Kaiwen W. Chen, Benjamin Demarco, Petr Broz Pubblicato in: European Journal of Immunology, 2019, ISSN 0014-2980 Editore: John Wiley & Sons Ltd. DOI: 10.1002/eji.201948254 Extrinsic and intrinsic apoptosis activate pannexin‐1 to drive NLRP 3 inflammasome assembly Autori: Kaiwen W Chen, Benjamin Demarco, Rosalie Heilig, Kateryna Shkarina, Andreas Boettcher, Christopher J Farady, Pawel Pelczar, Petr Broz Pubblicato in: The EMBO Journal, Issue 38/10, 2019, ISSN 0261-4189 Editore: Nature Publishing Group DOI: 10.15252/embj.2019101638 Genetic targeting of Card19 is linked to disrupted NINJ1 expression, impaired cell lysis, and increased susceptibility to Yersinia infection Autori: Elisabet Bjanes 1 2 , Reyna Garcia Sillas 2 , Rina Matsuda 1 2 , Benjamin Demarco 3 , Timothée Fettrelet 3 , Alexandra A DeLaney 1 2 , Opher S Kornfeld 4 , Bettina L Lee 4 , Eric M Rodríguez López 2 5 , Daniel Grubaugh 2 , Meghan A Wynosky-Dolfi 2 , Naomi H Philip 2 5 , Elise Krespan 2 6 , Dorothy Tovar 2 , Leonel Joannas 2 7 , Daniel P Beiting 2 6 8 , Jorge He Pubblicato in: Plos Pathogens, Issue 15537366, 2021, ISSN 1553-7366 Editore: Public Library of Science DOI: 10.1371/journal.ppat.1009967 The gasdermins, a protein family executing cell death and inflammation Autori: Petr Broz, Pablo Pelegrín, Feng Shao Pubblicato in: Nature Reviews Immunology, Issue 20/3, 2020, Page(s) 143-157, ISSN 1474-1733 Editore: Nature Publishing Group DOI: 10.1038/s41577-019-0228-2 Noncanonical inflammasome signaling elicits gasdermin D–dependent neutrophil extracellular traps Autori: Kaiwen W. Chen, Mercedes Monteleone, Dave Boucher, Gabriel Sollberger, Divya Ramnath, Nicholas D. Condon, Jessica B. von Pein, Petr Broz, Matthew J. Sweet, Kate Schroder Pubblicato in: Science Immunology, Issue 3/26, 2018, Page(s) eaar6676, ISSN 2470-9468 Editore: Science Immunology DOI: 10.1126/sciimmunol.aar6676 Cross talk between intracellular pathogens and cell death Autori: Benjamin Demarco, Kaiwen W. Chen, Petr Broz Pubblicato in: Immunological Reviews, Issue 297/1, 2020, Page(s) 174-193, ISSN 0105-2896 Editore: Blackwell Publishing Inc. DOI: 10.1111/imr.12892 Caspase-8–dependent gasdermin D cleavage promotes antimicrobial defense but confers susceptibility to TNF-induced lethality Autori: Benjamin Demarco, James P. Grayczyk, Elisabet Bjanes, Didier Le Roy, Wulf Tonnus, Charles-Antoine Assenmacher, Enrico Radaelli, Timothée Fettrelet, Vanessa Mack, Andreas Linkermann, Thierry Roger, Igor E. Brodsky, Kaiwen W. Chen, Petr Broz Pubblicato in: Science Advances, Issue 6/47, 2020, Page(s) eabc3465, ISSN 2375-2548 Editore: Science DOI: 10.1126/sciadv.abc3465 Caspase-1 cleaves Bid to release mitochondrial SMAC and drive secondary necrosis in the absence of GSDMD Autori: Rosalie Heilig, Marisa Dilucca, Dave Boucher, Kaiwen W Chen, Dora Hancz, Benjamin Demarco, Kateryna Shkarina, Petr Broz Pubblicato in: Life Science Alliance, Issue 3/6, 2020, Page(s) e202000735, ISSN 2575-1077 Editore: Life Science Alliance DOI: 10.26508/lsa.202000735 Optogenetic activators of apoptosis, necroptosis, and pyroptosis Autori: Shkarina K., Hasel de Carvalho E., Santos J.C., Ramos S., Leptin M., Broz P. Pubblicato in: JCB, Issue 00219525, 2022, ISSN 0021-9525 Editore: Rockefeller University Press DOI: 10.1083/jcb.202109038 The Opto-inflammasome in zebrafish as a tool to study cell and tissue responses to speck formation and cell death. Autori: Hasel de Carvalho E., Dharmadhikari S.S., Shkarina K., Xiong J.R., Reversade B., Broz P., Leptin M. Pubblicato in: eLife, Issue 2023, 2023, Page(s) e86373, ISSN 2050-084X Editore: eLife Sciences Publications DOI: 10.7554/elife.86373 Optogenetic Induction of Pyroptosis, Necroptosis, and Apoptosis in Mammalian Cell Lines. Autori: Shkarina K., Broz P. Pubblicato in: Bio-protocol, Issue n.a., 2023, Page(s) n.a., ISSN 2331-8325 Editore: Bio-protocol LLC DOI: 10.21769/bioprotoc.4762 Non-peer reviewed articles (2) Active membrane rupture spurs a range of cell deaths Autori: S. Hiller, P. Broz, Pubblicato in: Nature, Issue 00280836, 2021, ISSN 0028-0836 Editore: Nature Publishing Group DOI: 10.1038/d41586-021-00297-4 Divide to conquer: NLRP3 is activated on dispersed trans-Golgi network Autori: Kaiwen W. Chen, Dave Boucher, Petr Broz Pubblicato in: Cell Research, Issue 29/3, 2019, Page(s) 181-182, ISSN 1001-0602 Editore: Kexue Chubaneshe/Science Press DOI: 10.1038/s41422-018-0138-z È in corso la ricerca di dati su OpenAIRE... Si è verificato un errore durante la ricerca dei dati su OpenAIRE Nessun risultato disponibile
