Agent-Based Modelling of Gene Networks to model clonal selection in the tumour microenvironment and predict therapeutic resistance

Pubblicazioni

Guidelines for using sigQC for systematic evaluation of gene signatures

Autori: Andrew Dhawan, Alessandro Barberis, Wei-Chen Cheng, Enric Domingo, Catharine West, Tim Maughan, Jacob G. Scott, Adrian L. Harris, Francesca M. Buffa
Pubblicato in: Nature Protocols, Numero 14/5, 2019, Pagina/e 1377-1400, ISSN 1754-2189
Editore: Nature Publishing Group
DOI: 10.1038/s41596-019-0136-8

Modeling genotypes in their microenvironment to predict single- and multi-cellular behavior

Autori: Dimitrios Voukantsis, Kenneth Kahn, Martin Hadley, Rowan Wilson, Francesca M Buffa
Pubblicato in: GigaScience, Numero 8/3, 2019, ISSN 2047-217X
Editore: Oxford University Press
DOI: 10.1093/gigascience/giz010

Pan-cancer characterisation of microRNA across cancer hallmarks reveals microRNA-mediated downregulation of tumour suppressors

Autori: Andrew Dhawan, Jacob G. Scott, Adrian L. Harris, Francesca M. Buffa
Pubblicato in: Nature Communications, Numero 9/1, 2018, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-018-07657-1

Heritable genetic variants in key cancer genes link cancer risk with anthropometric traits

Autori: Matteo Di Giovannantonio, Benjamin HL Harris, Ping Zhang, Isaac Kitchen-Smith, Lingyun Xiong, Natasha Sahgal, Giovanni Stracquadanio, Marsha Wallace, Sarah Blagden, Simon Lord, David Harris, Adrian H.L. Harris, Francesca M. Buffa, Gareth L. Bond
Pubblicato in: Journal of Medical Genetics, 2020, Pagina/e jmedgenet-2019-106799, ISSN 0022-2593
Editore: British Medical Association
DOI: 10.1136/jmedgenet-2019-106799

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