Role of protein crystallization in type 2 immunity and asthma

Pubblicazioni

A bispecific antibody strategy to target multiple type 2 cytokines in asthma

Autori: Marie Godar, Kim Deswarte, Karl Vergote, Michael Saunders, Hans de Haard, Hamida Hammad, Christophe Blanchetot, Bart N. Lambrecht
Pubblicato in: Journal of Allergy and Clinical Immunology, Numero 142/4, 2018, Pagina/e 1185-1193.e4, ISSN 0091-6749
Editore: Mosby Inc.
DOI: 10.1016/j.jaci.2018.06.002

Epithelial dysregulation in obese severe asthmatics with gastro-oesophageal reflux

Autori: Jeanne-Marie Perotin, James P.R. Schofield, Susan J. Wilson, Jonathan Ward, Joost Brandsma, Fabio Strazzeri, Aruna Bansal, Xian Yang, Anthony Rowe, Julie Corfield, Rene Lutter, Dominick E. Shaw, Per S. Bakke, Massimo Caruso, Barbro Dahlén, Stephen J. Fowler, Ildikó Horváth, Peter Howarth, Norbert Krug, Paolo Montuschi, Marek Sanak, Thomas Sandström, Kai Sun, Ioannis Pandis, Charles Auffray, Be
Pubblicato in: European Respiratory Journal, Numero 53/6, 2019, Pagina/e 1900453, ISSN 0903-1936
Editore: European Respiratory Society
DOI: 10.1183/13993003.00453-2019

Inflammatory Type 2 cDCs Acquire Features of cDC1s and Macrophages to Orchestrate Immunity to Respiratory Virus Infection

Autori: Cedric Bosteels, Katrijn Neyt, Manon Vanheerswynghels, Mary J. van Helden, Dorine Sichien, Nincy Debeuf, Sofie De Prijck, Victor Bosteels, Niels Vandamme, Liesbet Martens, Yvan Saeys, Els Louagie, Manon Lesage, David L. Williams, Shiau-Choot Tang, Johannes U. Mayer, Franca Ronchese, Charlotte L. Scott, Hamida Hammad, Martin Guilliams, Bart N. Lambrecht
Pubblicato in: Immunity, Numero 52/6, 2020, Pagina/e 1039-1056.e9, ISSN 1074-7613
Editore: Cell Press
DOI: 10.1016/j.immuni.2020.04.005

Local immune response to food antigens drives meal-induced abdominal pain

Autori: Javier Aguilera-Lizarraga, Morgane V. Florens, Maria Francesca Viola, Piyush Jain, Lisse Decraecker, Iris Appeltans, Maria Cuende-Estevez, Naomi Fabre, Kim Van Beek, Eluisa Perna, Dafne Balemans, Nathalie Stakenborg, Stavroula Theofanous, Goele Bosmans, Stéphanie U. Mondelaers, Gianluca Matteoli, Sales Ibiza Martínez, Cintya Lopez-Lopez, Josue Jaramillo-Polanco, Karel Talavera, Yeranddy A. Alpiz
Pubblicato in: Nature, Numero 590/7844, 2021, Pagina/e 151-156, ISSN 0028-0836
Editore: Nature Publishing Group
DOI: 10.1038/s41586-020-03118-2

CCR2- and Flt3-Dependent Inflammatory Conventional Type 2 Dendritic Cells Are Necessary for the Induction of Adaptive Immunity by the Human Vaccine Adjuvant System AS01

Autori: Cedric Bosteels, Kaat Fierens, Sofie De Prijck, Justine Van Moorleghem, Manon Vanheerswynghels, Caroline De Wolf, Aurélie Chalon, Catherine Collignon, Hamida Hammad, Arnaud M. Didierlaurent, Bart N. Lambrecht
Pubblicato in: Frontiers in Immunology, Numero 11, 2021, ISSN 1664-3224
Editore: Front. Immunol
DOI: 10.3389/fimmu.2020.606805

Professional and ‘Amateur’ Antigen-Presenting Cells In Type 2 Immunity

Autori: Martijn J. Schuijs, Hamida Hammad, Bart N. Lambrecht
Pubblicato in: Trends in Immunology, Numero 40/1, 2019, Pagina/e 22-34, ISSN 1471-4906
Editore: Elsevier BV
DOI: 10.1016/j.it.2018.11.001

The ORMDL3 asthma susceptibility gene regulates systemic ceramide levels without altering key asthma features in mice

Autori: Nincy Debeuf, Assem Zhakupova, Regula Steiner, Sofie Van Gassen, Kim Deswarte, Farzaneh Fayazpour, Justine Van Moorleghem, Karl Vergote, Benjamin Pavie, Kelly Lemeire, Hamida Hammad, Thorsten Hornemann, Sophie Janssens, Bart N. Lambrecht
Pubblicato in: Journal of Allergy and Clinical Immunology, Numero 144/6, 2019, Pagina/e 1648-1659.e9, ISSN 0091-6749
Editore: Mosby Inc.
DOI: 10.1016/j.jaci.2019.06.041

Co-Activation of Glucocorticoid Receptor and Peroxisome Proliferator–Activated Receptor-γ in Murine Skin Prevents Worsening of Atopic March

Autori: Julie Deckers, Nadia Bougarne, Viacheslav Mylka, Sofie Desmet, Astrid Luypaert, Michael Devos, Giel Tanghe, Justine Van Moorleghem, Manon Vanheerswynghels, Lode De Cauwer, Jonathan Thommis, Marnik Vuylsteke, Jan Tavernier, Bart N. Lambrecht, Hamida Hammad, Karolien De Bosscher
Pubblicato in: Journal of Investigative Dermatology, Numero 138/6, 2018, Pagina/e 1360-1370, ISSN 0022-202X
Editore: Blackwell Publishing Inc.
DOI: 10.1016/j.jid.2017.12.023

IL-33trap is a novel IL-33–neutralizing biologic that inhibits allergic airway inflammation

Autori: Aurora Holgado, Harald Braun, Elien Van Nuffel, Sammy Detry, Martijn J. Schuijs, Kim Deswarte, Karl Vergote, Mira Haegman, Griet Baudelet, Jurgen Haustraete, Hamida Hammad, Bart N. Lambrecht, Savvas N. Savvides, Inna S. Afonina, Rudi Beyaert
Pubblicato in: Journal of Allergy and Clinical Immunology, Numero 144/1, 2019, Pagina/e 204-215, ISSN 0091-6749
Editore: Mosby Inc.
DOI: 10.1016/j.jaci.2019.02.028

Wnt and Hippo pathways in regulatory T cells: a NOTCH above in asthma

Autori: Hamida Hammad, Bart N. Lambrecht
Pubblicato in: Nature Immunology, Numero 21/11, 2020, Pagina/e 1313-1314, ISSN 1529-2908
Editore: Nature Publishing Group
DOI: 10.1038/s41590-020-0797-z

Isolated Schistosoma mansoni eggs prevent allergic airway inflammation

Autori: Katja Obieglo, Martijn J. Schuijs, Arifa Ozir-Fazalalikhan, Frank Otto, Yolanda van Wijck, Louis Boon, Bart N. Lambrecht, Christian Taube, Hermelijn H. Smits
Pubblicato in: Parasite Immunology, Numero 40/10, 2018, Pagina/e e12579, ISSN 0141-9838
Editore: Blackwell Publishing Inc.
DOI: 10.1111/pim.12579

How a farming environment protects from atopy

Autori: Julie Deckers, Bart N Lambrecht, Hamida Hammad
Pubblicato in: Current Opinion in Immunology, Numero 60, 2019, Pagina/e 163-169, ISSN 0952-7915
Editore: Elsevier BV
DOI: 10.1016/j.coi.2019.08.001

A pathophysiological role of PDE3 in allergic airway inflammation

Autori: Jan Beute, Melanie Lukkes, Ewout P. Koekoek, Hedwika Nastiti, Keerthana Ganesh, Marjolein J.W. de Bruijn, Steve Hockman, Menno van Nimwegen, Gert-Jan Braunstahl, Louis Boon, Bart N. Lambrecht, Vince C. Manganiello, Rudi W. Hendriks, Alex KleinJan
Pubblicato in: JCI Insight, Numero 3/2, 2018, ISSN 2379-3708
Editore: ASCI
DOI: 10.1172/jci.insight.94888

The hygiene hypothesis: immunological mechanisms of airway tolerance

Autori: Eline Haspeslagh, Ines Heyndrickx, Hamida Hammad, Bart N Lambrecht
Pubblicato in: Current Opinion in Immunology, Numero 54, 2018, Pagina/e 102-108, ISSN 0952-7915
Editore: Elsevier BV
DOI: 10.1016/j.coi.2018.06.007

Personalized medicine with biologics for severe type 2 asthma: current status and future prospects

Autori: Marie Godar, Christophe Blanchetot, Hans de Haard, Bart N. Lambrecht, Guy Brusselle
Pubblicato in: mAbs, Numero 10/1, 2018, Pagina/e 34-45, ISSN 1942-0870
Editore: Landes Bioscience
DOI: 10.1080/19420862.2017.1392425

Prophylactic allergen immunotherapy with Der p 2 prevents murine asthma by regulating lung GM-CSF

Autori: Eline Haspeslagh, Manon Vanheerswynghels, Kim Deswarte, Justine Van Moorleghem, Alain Jacquet, Bart N. Lambrecht, Hamida Hammad
Pubblicato in: Journal of Allergy and Clinical Immunology, Numero 143/6, 2019, Pagina/e 2307-2311.e5, ISSN 0091-6749
Editore: Mosby Inc.
DOI: 10.1016/j.jaci.2019.02.007

Charcot-Leyden crystals promote neutrophilic inflammation in patients with nasal polyposis

Autori: Elien Gevaert, Tim Delemarre, Joyceline De Volder, Nan Zhang, Gabriele Holtappels, Natalie De Ruyck, Emma Persson, Ines Heyndrickx, Kenneth Verstraete, Helena Aegerter, Hans Nauwynck, Savvas N. Savvides, Bart N. Lambrecht, Claus Bachert
Pubblicato in: Journal of Allergy and Clinical Immunology, Numero 145/1, 2020, Pagina/e 427-430.e4, ISSN 0091-6749
Editore: Mosby Inc.
DOI: 10.1016/j.jaci.2019.08.027

Protein crystallization promotes type 2 immunity and is reversible by antibody treatment

Autori: Emma K. Persson, Kenneth Verstraete, Ines Heyndrickx, Elien Gevaert, Helena Aegerter, Jean-Michel Percier, Kim Deswarte, Koen H. G. Verschueren, Ann Dansercoer, Delphine Gras, Pascal Chanez, Claus Bachert, Amanda Gonçalves, Hanne Van Gorp, Hans De Haard, Christophe Blanchetot, Michael Saunders, Hamida Hammad, Savvas N. Savvides, Bart N. Lambrecht
Pubblicato in: Science, Numero 364/6442, 2019, Pagina/e eaaw4295, ISSN 0036-8075
Editore: American Association for the Advancement of Science
DOI: 10.1126/science.aaw4295

Tnfaip3 expression in pulmonary conventional type 1 Langerin‐expressing dendritic cells regulates T helper 2‐mediated airway inflammation in mice

Autori: Heleen Vroman, Denise Uden, Ingrid M. Bergen, Jennifer A. C. Hulst, Melanie Lukkes, Geert Loo, Björn E. Clausen, Louis Boon, Bart N. Lambrecht, Hamida Hammad, Rudi W. Hendriks, Mirjam Kool
Pubblicato in: Allergy, Numero 75/10, 2020, Pagina/e 2587-2598, ISSN 0105-4538
Editore: Blackwell Publishing Inc.
DOI: 10.1111/all.14334

Characterization of a lung epithelium specific E-cadherin knock-out model: Implications for obstructive lung pathology

Autori: S. Post, I. H. Heijink, L. Hesse, H. K. Koo, F. Shaheen, M. Fouadi, V. N. S. Kuchibhotla, B. N. Lambrecht, A. J. M. Van Oosterhout, T. L. Hackett, M. C. Nawijn
Pubblicato in: Scientific Reports, Numero 8/1, 2018, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-018-31500-8

Eicosanoid Control Over Antigen Presenting Cells in Asthma

Autori: Nincy Debeuf, Bart N. Lambrecht
Pubblicato in: Frontiers in Immunology, Numero 9, 2018, ISSN 1664-3224
Editore: IUIS
DOI: 10.3389/fimmu.2018.02006

An anti‐siglec‐8 antibody depletes sputum eosinophils from asthmatic subjects and inhibits lung mast cells

Autori: Sheena C. Kerr, Jeanmarie R. Gonzalez, Julia Schanin, Michael C. Peters, Bart N. Lambrecht, Emily C. Brock, Annabelle Charbit, K. M. Ansel, Bradford A. Youngblood, John V. Fahy
Pubblicato in: Clinical & Experimental Allergy, Numero 50/8, 2020, Pagina/e 904-914, ISSN 0954-7894
Editore: Blackwell Publishing Inc.
DOI: 10.1111/cea.13681

Osteopontin Promotes Protective Antigenic Tolerance against Experimental Allergic Airway Disease

Autori: Themis Alissafi, Evangelia Kourepini, Davina C. M. Simoes, Nikolaos Paschalidis, Maria Aggelakopoulou, Tim Sparwasser, Louis Boon, Hamida Hammad, Bart N. Lambrecht, Vily Panoutsakopoulou
Pubblicato in: The Journal of Immunology, Numero 200/4, 2018, Pagina/e 1270-1282, ISSN 0022-1767
Editore: American Association of Immunologists
DOI: 10.4049/jimmunol.1701345

Human Lung Conventional Dendritic Cells Orchestrate Lymphoid Neogenesis during Chronic Obstructive Pulmonary Disease

Autori: Thomas Naessens, Yannick Morias, Eva Hamrud, Ulf Gehrmann, Ramachandramouli Budida, Johan Mattsson, Tina Baker, Gabriel Skogberg, Elisabeth Israelsson, Kristofer Thörn, Martijn J. Schuijs, Bastian Angermann, Faye Melville, Karl J. Staples, Danen M. Cunoosamy, Bart N. Lambrecht
Pubblicato in: American Journal of Respiratory and Critical Care Medicine, Numero 202/4, 2020, Pagina/e 535-548, ISSN 1073-449X
Editore: American Thoracic Society
DOI: 10.1164/rccm.201906-1123oc

TAO-kinase 3 governs the terminal differentiation of NOTCH2-dependent splenic conventional dendritic cells

Autori: Matthias Vanderkerken, Bastiaan Maes, Lana Vandersarren, Wendy Toussaint, Kim Deswarte, Manon Vanheerswynghels, Philippe Pouliot, Liesbet Martens, Sofie Van Gassen, Connie M. Arthur, Margaret E. Kirkling, Boris Reizis, Daniel Conrad, Sean Stowell, Hamida Hammad, Bart N. Lambrecht
Pubblicato in: Proceedings of the National Academy of Sciences, Numero 117/49, 2020, Pagina/e 31331-31342, ISSN 0027-8424
Editore: National Academy of Sciences
DOI: 10.1073/pnas.2009847117

È in corso la ricerca di dati su OpenAIRE...

Pubblicazioni

Condividi questa pagina

Scarica