In MATRIX-B project, the objectives and goals have been conducted via 3 specific work packages (WPs). WP1 included 2 research studies, addressed to prepare the magnetic particles in the fluids and understand the dynamic evolution of this under TM fields. This resulted in 1 institutional seminar communication, 1 conference seminar and 1 journal publication to date, with an additional 1 journal manuscript underway. The aim of WP2 was to evaluate the mechanical properties of the biocolloids under TM fields. In it, she delivered 1 conference seminar, 1 poster communication and 1 institutional seminar, with 1 journal manuscript underway. WP3 included study the response of cells in MR fluids (in vitro studies), the process of aggregation of the MR fluids with in vivo experiments in the presence of TM fields. Under WP3, the Fellow received the admission to 2 conference seminars and 1 poster communication, and she delivered 1 journal publication to date. An additional journal manuscript is currently underway. For researcher training and transfer-of-knowledge, the Fellow has participated in 2 conferences, 3 intensive training courses and 13 short courses to improve the knowledge and obtain the necessary training skills to work in the MATRIX-B project. She obtained a teaching qualification in Spain (Aneca), and she has had the opportunity to join the host University as a lecturer to teach undergraduate students, and, also, she has supervised a student of the Master and the final degree project of 2 students. She was invited as Guest Editor of a special issue of the Applied Sciences journal, and, also, she was appointed Editorial Board member of the Applied Sciences. The Fellow delivered 8 public engagement activities (2 departmental seminars and 6 outreach activities) to popularize MATRIX-B project, communicate findings and promoting gender parity, showing that women's access to the core of scientific and technological practice is possible and necessary. During the grant, the Fellow has implemented the host lab instrumentation, creating a new lab dedicated to the preparation of magnetic biomaterials and their cellular characterization. The results of this MSCA are described in (1) a detailed review on different kinds of thermoresponsive nanomaterials (TRN), including magnetic biomaterials, discussing their potential and the physical mechanisms; (2) a second detailed review on the clinical trials carried out on TRN, specifying their use in diagnosis and treatment of different diseases; (3) three forthcoming papers on how through TM fields it is possible to accurately generate and control chemical/mechanical activity and cellular interaction of the new magnetic biomaterials. The results obtained and data sets collected during this MSCA will allow the publication of other papers, in addition to those mentioned above, and also pave the way to new research lines that are still unexplored in the use of TM fields for the preparation of smart biomaterials for regenerative medicine.
