Risultati finali Other (1) ESR project vacancies advertised Websites, patent fillings, videos etc. (6) E-newsletter 2 published Enewsletter 2 published International Conference on Synthetic Glycobiology E-newsletter 1 published Enewsletter 1 published E-newsletter3 published Enewsletter3 published synBIOcarb website running (public section) synBIOcarb website running public section Report on one day contact meeting with industry Pubblicazioni Other (2) Membrane fusion mediated by non-covalent binding of re-engineered cholera toxin assemblies to glycolipids Autori: Sarah Wehrum; Daniel J Williamson; Lina Siukstaite; Thomas R Branson; Taras Sych; Josef Madl; Gemma C Wildsmith; Wenyue Dai; James F Ross; Maren Thomsen; Michael E Webb; Winfried Römer; W Bruce Turnbull Pubblicato in: ChemRxiv, 2021 Editore: Cambridge University Press DOI: 10.26434/chemrxiv-2021-j9stg A pore-forming β-trefoil lectin with specificity for the tumor-related glycosphingolipid Gb3 Autori: Simona Notova, François Bonnardel, Francesca Rosato, Lina Siukstaite, Jessica Schwaiger, Nicolai Bovin, Annabelle Varrot, Winfried Römer, Frédérique Lisacek, Anne Imberty Pubblicato in: BioRxiv, 2022 Editore: Cold Harbour Spring Laboratory DOI: 10.1101/2022.02.10.479907 Peer reviewed articles (32) Building an Artificial Plant Cell Wall on a Lipid Bilayer by Assembling Polysaccharides and Engineered Proteins Autori: Simona Notova; Nathan Cannac; Luca Rabagliati; Maeva Touzard; Josselin Mante; Yotam Navon; Liliane Coche-Guérente; Olivier Lerouxel; Laurent Heux; Anne Imberty Pubblicato in: "ACS Synthetic Biology, American Chemical Society, 2022, ⟨10.1021/acssynbio.2c00404⟩", Issue 11/10, 2022, ISSN 2161-5063 Editore: American Chemical Society DOI: 10.1021/acssynbio.2c00404 Tuning specificity and topology of lectins through synthetic biology Autori: Simona Notova, Anne Imberty Pubblicato in: Current Opinion on Chemical Biology, Issue 73, 2023, Page(s) 102275, ISSN 1367-5931 Editore: Elsevier BV DOI: 10.1016/j.cbpa.2023.102275 The Two Sweet Sides of Janus Lectin Drive Crosslinking of Liposomes to Cancer Cells and Material Uptake Autori: Lina Siukstaite, Francesca Rosato, Anna Mitrovic, Peter Fritz Müller, Katharina Kraus, Simona Notova, Anne Imberty, Winfried Römer Pubblicato in: Toxins, Issue 13/11, 2021, Page(s) 792, ISSN 2072-6651 Editore: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/toxins13110792 Structural Diversities of Lectins Binding to the Glycosphingolipid Gb3 Autori: Lina Siukstaite, Anne Imberty, Winfried Römer Pubblicato in: Frontiers in Molecular Biosciences, Issue 8, 2021, ISSN 2296-889X Editore: Frontiers in Molecular Biosciences DOI: 10.3389/fmolb.2021.704685 The choanoflagellate pore-forming lectin SaroL-1 punches holes in cancer cells by targeting the tumor-related glycosphingolipid Gb3 Autori: Simona Notova; François Bonnardel; Francesca Rosato; Lina Siukstaite; Jessica Schwaiger; Jia Hui Lim; Nicolai Bovin; Annabelle Varrot; Yu Ogawa; Winfried Römer; Frédérique Lisacek; Anne Imberty Pubblicato in: Communications Biology, Issue 5/954, 2022, ISSN 2399-3642 Editore: Springer Nature Ltd DOI: 10.1038/s42003-022-03869-w Identification of Whole-Serum Glycobiomarkers for Colorectal Carcinoma Using Reverse-Phase Lectin Microarray Autori: Tomas Berto, Aniko Bertokova, Eduard Jane, Michal Hires, Juvissan Aguedo, Maria Potocarova, Ludovit Lukac, Alica Vikartovska, Peter Kasak, Lubor Borsig and Jan Tkac Pubblicato in: Frontiers in Oncology, Issue 11, 2021, Page(s) 735338, ISSN 2234-943X Editore: Frontiers Media S. A. DOI: 10.3389/fonc.2021.735338 Structure and engineering of tandem repeat lectins Autori: Simona Notova, François Bonnardel, Frédérique Lisacek, Annabelle Varrot, Anne Imberty Pubblicato in: Current Opinion in Structural Biology, Issue 62, 2020, Page(s) 39-47, ISSN 0959-440X Editore: Elsevier BV DOI: 10.1016/j.sbi.2019.11.006 Electrochemical Impedance Spectroscopy on 2D Nanomaterial MXene Modified Interfaces: Application as a Characterization and Transducing Tool Autori: Juvissan Aguedo, Lenka Lorencova, Marek Barath, Pavol Farkas and Jan Tkac Pubblicato in: Chemosensors, Issue 8/4, 2020, Page(s) 127, ISSN 2227-9040 Editore: MDPI DOI: 10.3390/chemosensors8040127 Membrane Fusion Mediated by Non-covalent Binding of Re-engineered Cholera Toxin Assemblies to Glycolipids Autori: Sarah Wehrum, Lina Siukstaite, Daniel J. Williamson, Thomas R. Branson, Taras Sych, Josef Madl, Gemma C. Wildsmith, Wenyue Dai, Erik Kempmann, James F. Ross, Maren Thomsen, Michael E. Webb, Winfried Römer, and W. Bruce Turnbull Pubblicato in: ACS Synthetic Biology, Issue 11 (12), 2022, Page(s) 3929–3938, ISSN 2161-5063 Editore: American Chemical Society DOI: 10.1021/acssynbio.2c00266 Genetic code expansion in E. coli enables production of a functional‘ready-to-click’ T cell receptor-specific scFv Autori: Rajeev Pasupuleti, Francesca Rosato, Dajana Kolanovic, Olga N. Makshakova, Winfried Römer and Birgit Wiltschi Pubblicato in: New Biotechnology, Issue 76, 2023, Page(s) 127-137, ISSN 1871-6784 Editore: Elsevier BV DOI: 10.1016/j.nbt.2023.05.007 Building an Artificial Plant Cell Wall on a Lipid Bilayer by Assembling Polysaccharides and Engineered Proteins Autori: Simona Notova; Nathan Cannac; Luca Rabagliati; Maeva Touzard; Josselin Mante; Yotam Navon; Liliane Coche-Guérente; Olivier Lerouxel; Laurent Heux; Anne Imberty Pubblicato in: ACS Synthetic Biology, Issue 11/10, 2022, Page(s) 3516–3528, ISSN 2161-5063 Editore: American Chemical Society DOI: 10.1021/acssynbio.2c00404 Extending Janus lectins architecture: Characterization and application to protocells Autori: Simona Notova, Lina Siukstaite, Francesca Rosato, Federica Vena, Aymeric Audfray, Nicolai Bovin, Ludovic Landemarre, Winfried Römer, Anne Imberty Pubblicato in: Computational and Structural Biotechnology Journal, Issue 20, 2022, Page(s) 6108-6119, ISSN 2001-0370 Editore: Elsevier DOI: 10.1016/j.csbj.2022.11.005 Microbial carbohydrate-binding toxins – From etiology to biotechnological application Autori: Natalia Danielewicz; Francesca Rosato; Wenyue Dai; Winfried Römer; W. Bruce Turnbull; Juergen Mairhofer Pubblicato in: Biotechnology Advances, 2022, ISSN 0734-9750 Editore: Elsevier BV DOI: 10.1016/j.biotechadv.2022.107951 Homo-and Heterovalent Neoglycoproteins as Ligands for Bacterial Lectins Autori: David Goyard, Benoît Roubinet, Federica Vena, Ludovic Landemarre, Olivier Renaudet Pubblicato in: ChemPlusChem, Issue 87/2, 2022, ISSN 2192-6506 Editore: Wiley-VCH Verlag DOI: 10.1002/cplu.202100481 Piggybacking on the Cholera Toxin: Identification of a CTB-Binding Protein as an Approach for Targeted Delivery of Proteins to Motor Neurons. Autori: Matthew R Balmforth; Jessica L Haigh; Vajinder Kumar; Vajinder Kumar; Wenyue Dai; Christian Tiede; Darren C. Tomlinson; Jim Deuchars; Michael E. Webb; W. Bruce Turnbull Pubblicato in: Bioconjugate Chemistry, Issue 3, 2021, ISSN 1043-1802 Editore: American Chemical Society DOI: 10.1021/acs.bioconjchem.1c00373 Microbial carbohydrate-binding toxins – From etiology to biotechnological application Autori: Natalia Danielewicz; Francesca Rosato; Wenyue Dai; Winfried Römer; W. Bruce Turnbull; Juergen Mairhofer Pubblicato in: Biotechnology Advances, Issue 59, 2022, ISSN 0734-9750 Editore: Elsevier BV DOI: 10.1016/j.biotechadv.2022.107951 A Holistic 4D Approach to Optimize Intrinsic and Extrinsic Factors Contributing to Variability in Microarray Biosensing in Glycomics Autori: Paras H. Kundalia , Lucia Pažitná, Kristína Kianičková, Eduard Jáné, Lenka Lorencová, Jaroslav Katrlík Pubblicato in: Sensors, Issue 23(12), 2023, ISSN 1424-8220 Editore: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/s23125362 Enzymatic Glyco-Modification of Synthetic Membrane Systems Autori: Dylan Jabeguero, Lina Siukstaite, Chunyue Wang, Anna Mitrovic, Serge Pérez, Olga Makshakova, Ralf P. Richter, Winfried Römer and Christelle Breton Pubblicato in: Biomolecules, Issue 13(2), 2023, Page(s) 335, ISSN 2218-273X Editore: MDPI DOI: 10.3390/biom13020335 Clickable Shiga Toxin B Subunit for Drug Delivery in Cancer Therapy Autori: Natalia Danielewicz, Wenyue Dai, Francesca Rosato, Michael E. Webb, Gerald Striedner,Winfried Römer,W. Bruce Turnbull, Juergen Mairhofer Pubblicato in: ACS Omega, Issue 8 (17), 2023, Page(s) 15406–15421, ISSN 2470-1343 Editore: American Chemical Society DOI: 10.1021/acsomega.3c00667 Targeted delivery of oligonucleotides using multivalent protein–carbohydrate interactions Autori: Vajinder Kumar and W. Bruce Turnbull Pubblicato in: Chemical Society Reviews, Issue 52, 2023, Page(s) 1273-1287, ISSN 1460-4744 Editore: Royal Society of Chemistry DOI: 10.1039/d2cs00788f Neutralizing the Impact of the Virulence Factor LecA from <i>Pseudomonas aeruginosa</i> on Human Cells with New Glycomimetic Inhibitors Autori: Eva Zahorska; Francesca Rosato; Kai Stober; Sakonwan Kuhaudomlarp; Joscha Meiers; Dirk Hauck; Dorina Reith; Emilie Gillon; Katharina Rox; Anne Imberty; Winfried Römer; Alexander Titz Pubblicato in: Angewandte Chemie International Edition, Issue 62, 2023, ISSN 1433-7851 Editore: John Wiley & Sons Ltd. DOI: 10.1002/anie.202215535 The Lectin LecA Sensitizes the Human Stretch-Activated Channel TREK-1 but Not Piezo1 and Binds Selectively to Cardiac Non-myocytes Autori: Elisa Darkow, Eva A. Rog-Zielinska, Josef Madl, Annette Brandel, Lina Siukstaite, Ramin Omidvar, Peter Kohl, Ursula Ravens, Winfried Römer, Rémi Peyronnet Pubblicato in: Frontiers in Physiology, Issue 11, 2020, ISSN 1664-042X Editore: Frontiers Research Foundation DOI: 10.3389/fphys.2020.00457 In-Depth Characterization of a Re-Engineered Cholera Toxin Manufacturing Process Using Growth-Decoupled Production in Escherichia coli Autori: Natalia Danielewicz, Wenyue Dai, Francesca Rosato, Michael E. Webb, Gerald Striedner,Winfried Römer,W. Bruce Turnbull, Juergen Mairhofer Pubblicato in: Toxins, 2022, ISSN 2072-6651 Editore: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/toxins14060396 MXene as a novel cartridge for N-glycan enrichment Autori: Juvissan Aguedo, Zuzana Pakanova, Lenka Lorencova, Marek Nemcovic, Peter Kasak, Marek Barath, Pavol Farkas, JanTkac Pubblicato in: Analytica Chimica Acta, Issue 00032670, 2022, Page(s) Volume 1234, ISSN 0003-2670 Editore: Elsevier BV DOI: 10.1016/j.aca.2022.340512 A bispecific, crosslinking lectibody activates cytotoxic T cells and induces cancer cell death Autori: Francesca Rosato, Rajeev Pasupuleti, Jana Tomisch, Ana Valeria Meléndez, Dajana Kolanovic, Olga N. Makshakova, Birgit Wiltschi & Winfried Römer Pubblicato in: Journal of Translational Medicine, Issue 20/578, 2022, ISSN 1479-5876 Editore: BioMed Central DOI: 10.1186/s12967-022-03794-w Stabilization of membrane topologies by proteinaceous remorin scaffolds Autori: Chao Su, Marta Rodriguez-Franco, Beatrice Lace, Nils Nebel, Casandra Hernandez-Reyes, Pengbo Liang, Eija Schulze, Evgeny V Mymrikov, Nikolas M Gross, Julian Knerr, Hong Wang, Lina Siukstaite, Jean Keller, Cyril Libourel, Alexandra AM Fischer, Katharina E Gabor, Eric Mark, Claudia Popp, Carola Hunte, Wilfried Weber, Petra Wendler, Thomas Stanislas, Pierre-Marc Delaux, Oliver Einsle, Robert Grosse, Pubblicato in: Nature Comunications, Issue 14/323, 2023, ISSN 2041-1723 Editore: Nature Publishing Group DOI: 10.1038/s41467-023-35976-5 Novel lectin-based chimeric antigen receptors target Gb3-positive tumour cells Autori: Ana Valeria Meléndez, Rubí M.-H. Velasco Cárdenas, Simon Lagies, Juliane Strietz, Lina Siukstaite, Oliver S. Thomas, Jana Tomisch, Wilfried Weber, Bernd Kammerer, Winfried Römer, Susana Minguet Pubblicato in: Cellular and Molecular Life Sciences, Issue 1420682X, 2022, ISSN 1420-682X Editore: Birkhauser Verlag DOI: 10.1007/s00018-022-04524-7 Piggybacking on the Cholera Toxin: Identification of a CTB-Binding Protein as an Approach for Targeted Delivery of Proteins to Motor Neurons. Autori: Matthew R. Balmforth; Jessica L. Haigh; Vajinder Kumar; Vajinder Kumar; Wenyue Dai; Christian Tiede; Darren C. Tomlinson; Jim Deuchars; Michael E. Webb; W. Bruce Turnbull Pubblicato in: Bioconjugate Chemistry, Issue 32 (10), 2021, Page(s) 2205–2212, ISSN 1043-1802 Editore: American Chemical Society DOI: 10.1021/acs.bioconjchem.1c00373 The choanoflagellate pore-forming lectin SaroL-1 punches holes in cancer cells by targeting the tumor-related glycosphingolipid Gb3 Autori: Simona Notova; François Bonnardel; Francesca Rosato; Lina Siukstaite; Jessica Schwaiger; Jia Hui Lim; Nicolai Bovin; Annabelle Varrot; Yu Ogawa; Winfried Römer; Frédérique Lisacek; Anne Imberty Pubblicato in: Communications Biology, Issue 5/954, 2022, ISSN 2399-3642 Editore: Nature Publising Group DOI: 10.1038/s42003-022-03869-w Polyvalent Transition-State Analogues of Sialyl Substrates Strongly Inhibit Bacterial Sialidases Autori: Coralie Assailly, Clarisse Bridot, Dr. Amélie Saumonneau, Paul Lottin, Dr. Benoit Roubinet, Dr. Eva-Maria Krammer, Francesca François, Federica Vena, Dr. Ludovic Landemarre, Dr. Dimitri Alvarez Dorta, Dr. David Deniaud, Dr. Cyrille Grandjean, Dr. Charles Tellier, Dr. Sagrario Pascual, Dr. Véronique Montembault, Dr. Laurent Fontaine, Dr. Franck Daligault, Dr. Julie Bouckaert, Dr. Sébastien G. G Pubblicato in: Chemistry – A European Journal, Issue 27, 2021, Page(s) 3142-3150, ISSN 1521-3765 Editore: Wiley-VCH DOI: 10.1002/chem.202004672 Involvement of N‐glycans in binding of Photorhabdus luminescens Tc toxin Autori: Peter Njenga Ng'ang'a, Lina Siukstaite, Alexander E. Lang, Hans Bakker, Winfried Römer, Klaus Aktories, Gudula Schmidt Pubblicato in: Cellular Microbiology, Issue Monthly, 2021, ISSN 1462-5814 Editore: Blackwell Publishing Inc. DOI: 10.1111/cmi.13326 Neutralizing the Impact of the Virulence Factor LecA from <i>Pseudomonas aeruginosa</i> on Human Cells with New Glycomimetic Inhibitors Autori: Eva Zahorska; Francesca Rosato; Kai Stober; Sakonwan Kuhaudomlarp; Joscha Meiers; Dirk Hauck; Dorina Reith; Emilie Gillon; Katharina Rox; Anne Imberty; Winfried Römer; Alexander Titz Pubblicato in: "Angewandte Chemie International Edition, In press, ⟨10.1002/anie.202215535⟩", Issue 62/7, 2022, ISSN 1433-7851 Editore: John Wiley & Sons Ltd. DOI: 10.1002/anie.202215535 È in corso la ricerca di dati su OpenAIRE... Si è verificato un errore durante la ricerca dei dati su OpenAIRE Nessun risultato disponibile
