Periodic Reporting for period 1 - MalusEdit (Malus genome editing via CRISPR/Cas9 to develop sustainable pest free apples)
Okres sprawozdawczy: 2019-10-16 do 2021-10-15
Another important outcome of the MalusEdit project was the development of a procedure to regenerate a whole plant from a single cell. This will allow the use of gene editing applications that do not make any use of DNA intermediates. The regeneration procedure can now be used to speed up apple breeding projects and thus deliver in short time apples that are improved for multiple important agronomical traits towards real sustainable agriculture.
The single-cell regeneration protocol which was developed during MalusEdit will permit unlocking the full potential of gene editing allowing DNA-free applications of this technology in apple. Within a less restrictive EU regulation on DNA-free gene-edited plants, this regeneration procedure will speed up apple breeding programs aimed at developing sustainable disease-resistant and quality-enhanced apples with a huge positive impact on human health and the environment.