Projektbeschreibung
Forschungsförderung für Infektionsbiologie in Estland
Die Entdeckung des Penicillins 1928 markiert den Beginn des Antibiotikazeitalters, revolutionierte die Behandlung von Infektionskrankheiten und reduzierte drastisch die Zahl der Todesfälle. Jedoch kann es nach einigen Jahren, insbesondere bei latenten Infektionserregern, über Zeiträume von Monaten oder Jahren zur Reaktivierung kommen, was weltweit noch immer Ursache für hohe Krankheits- und Sterberaten ist. Das EU-finanzierte Projekt MIBEst soll den Kenntnisstand in der Infektionsbiologie erweitern, mit dem Schwerpunkt auf neuen Modellen für latente Infektionen. Das Projekt stärkt Forschungskapazitäten zu latenten und chronischen Infektionen am estnischen Technologieinstitut der Universität Tartu und stellt hierfür Kooperationen mit führenden Universitäten in Schweden und der Schweiz her.
Ziel
Infectious diseases have been the leading cause of death for many centuries. The development of vaccination and antibiotic treatments combined with improved hygiene has decreased the number of deaths, but the mortality and morbidity associated with infections remain considerable, requiring constant societal awareness and scientific research. An increasing concern are the latent and chronic infections that are often refractory to treatments. As the frequency of latent infections increases with age, it is a major concern for aging societies. The great diversity of the infectious agents, and the multidisciplinary nature of the infectious biology research demand a convergence of various competencies: microbiology, cell biology, animal infection models, immunology etc, emphasizing the need for collaboration between research centres. Especially important are joint activities for smaller countries, e.g. Estonia, where establishment of full-scale stand-alone programs is not economically feasible. Despite the strong positions in basic molecular biology, virology and microbiology, Estonia often fails to capitalize on the excellence in basic research by transitioning to the development of therapeutics targeting medically relevant processes. The main objective of the MIBEst project is to strengthen the research capacity on latent and chronic infections of Institute of Technology at University of Tartu by creating long-lasting links with internationally-leading research institutions: Molecular Infection Medicine Sweden at Umeå University, Sweden, and Basel Biozentrum, University of Basel, Switzerland. As an outcome of MIBEst, Estonian scientists will have new knowledge in infection biology with particular focus on advancement in models for latent infections and high throughput screening for promising candidates for antiinfective compounds. Altogether, it enables development of new anti-infection strategies that will have major impact at the national, European and global scale.
Wissenschaftliches Gebiet
Schlüsselbegriffe
Programm/Programme
- H2020-EU.4.b. - Twinning of research institutions Main Programme
Thema/Themen
Aufforderung zur Vorschlagseinreichung
Andere Projekte für diesen Aufruf anzeigenUnterauftrag
H2020-WIDESPREAD-2018-03
Finanzierungsplan
CSA - Coordination and support actionKoordinator
51005 Tartu
Estland