Descrizione del progetto
Rafforzamento della ricerca sulla biologia delle infezioni in Estonia
Nel 1928 la scoperta della penicillina segnò l’inizio dell’era degli antibiotici, rivoluzionando la cura delle malattie infettive e riducendo drasticamente il numero dei decessi. Nel corso del tempo le infezioni, soprattutto quelle latenti, possono riattivarsi nell’arco di mesi e anni e sono ancora oggi causa di elevati tassi di morbilità e mortalità in tutto il mondo. Il progetto MIBEst, finanziato dall’UE, mira ad approfondire le conoscenze scientifiche nel campo della biologia delle infezioni, con particolare attenzione al progresso dei modelli per le infezioni latenti. Il progetto rafforzerà la capacità di ricerca dell’Istituto estone di tecnologia dell’Università di Tartu nel campo delle infezioni latenti e croniche, creando legami con importanti università svedesi e svizzere.
Obiettivo
Infectious diseases have been the leading cause of death for many centuries. The development of vaccination and antibiotic treatments combined with improved hygiene has decreased the number of deaths, but the mortality and morbidity associated with infections remain considerable, requiring constant societal awareness and scientific research. An increasing concern are the latent and chronic infections that are often refractory to treatments. As the frequency of latent infections increases with age, it is a major concern for aging societies. The great diversity of the infectious agents, and the multidisciplinary nature of the infectious biology research demand a convergence of various competencies: microbiology, cell biology, animal infection models, immunology etc, emphasizing the need for collaboration between research centres. Especially important are joint activities for smaller countries, e.g. Estonia, where establishment of full-scale stand-alone programs is not economically feasible. Despite the strong positions in basic molecular biology, virology and microbiology, Estonia often fails to capitalize on the excellence in basic research by transitioning to the development of therapeutics targeting medically relevant processes. The main objective of the MIBEst project is to strengthen the research capacity on latent and chronic infections of Institute of Technology at University of Tartu by creating long-lasting links with internationally-leading research institutions: Molecular Infection Medicine Sweden at Umeå University, Sweden, and Basel Biozentrum, University of Basel, Switzerland. As an outcome of MIBEst, Estonian scientists will have new knowledge in infection biology with particular focus on advancement in models for latent infections and high throughput screening for promising candidates for antiinfective compounds. Altogether, it enables development of new anti-infection strategies that will have major impact at the national, European and global scale.
Campo scientifico
Parole chiave
Programma(i)
- H2020-EU.4.b. - Twinning of research institutions Main Programme
Argomento(i)
Invito a presentare proposte
Vedi altri progetti per questo bandoBando secondario
H2020-WIDESPREAD-2018-03
Meccanismo di finanziamento
CSA - Coordination and support actionCoordinatore
51005 Tartu
Estonia