What makes a successfull pathogen? Understanding the impact of cell-to-cell heterogeneity in chromatin structure on infection and adaptation

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Summer school with invited speakers held

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Publicaciones

The molecular grammar of protein disorder guiding genome-binding locations

Autores: Felix Jonas, Miri Carmi, Beniamin Krupkin, Joseph Steinberger, Sagie Brodsky, Tamar Jana, Naama Barkai
Publicado en: Nucleic Acids Research, Edición Vol. 51, Edición 10, 2023, Página(s) 4831-4844, ISSN 0305-1048
Editor: Oxford University Press
DOI: 10.1093/nar/gkad184

Cell-to-Cell Heterogeneity in Trypanosomes

Autores: Vanessa Luzak, Lara López-Escobar, T. Nicolai Siegel, Luisa M. Figueiredo
Publicado en: Annual Review of Microbiology, Edición 75/1, 2021, Página(s) 107-128, ISSN 0066-4227
Editor: Annual Reviews, Inc.
DOI: 10.1146/annurev-micro-040821-012953

The inner nuclear membrane protein Lem2 coordinates RNA degradation at the nuclear periphery

Autores: Lucía Martín Caballero, Matías Capella, Ramón Ramos Barrales, Nikolay Dobrev, Thomas van Emden, Yasuhiro Hirano, Vishnu N. Suma Sreechakram, Sabine Fischer-Burkart, Yasuha Kinugasa, Alicia Nevers, Mathieu Rougemaille, Irmgard Sinning, Tamás Fischer, Yasushi Hiraoka & Sigurd Braun
Publicado en: Nature Structural & Molecular Biology, Edición Vol. 29, 2022, Página(s) 910-921, ISSN 1545-9993
Editor: Nature Publishing Group
DOI: 10.1038/s41594-022-00831-6

The 3-phosphoinositide-dependent protein kinase 1 is an essential upstream activator of protein kinase A in malaria parasites

Autores: Eva Hitz, Natalie Wiedemar, Armin Passecker, Beatriz A. S. Graça, Christian Scheurer, Sergio Wittlin, Nicolas M. B. Brancucci, Ioannis Vakonakis, Pascal Mäser, Till S. Voss
Publicado en: PLoS Biology, Edición 19(12), 2021, ISSN 1545-7885
Editor: Plos
DOI: 10.1371/journal.pbio.3001483

A genome-wide map of DNA replication at single-molecule resolution in the malaria parasite Plasmodium falciparum

Autores: Francis Isidore Garcia Totañes, Jonas Gockel, Sarah E. Chapman, Richárd Bártfai, Michael A. Boemo, Catherine J. Merrick
Publicado en: Nucleic Acids Research, Edición Volume 51, Edición 6, 2023, Página(s) 2709-2724, ISSN 0305-1048
Editor: Oxford University Press
DOI: 10.1093/nar/gkad093

m6A landscape is more pervasive when Trypanosoma brucei exits the cell cycle

Autores: Lúcia Serra, Sara Silva Pereira, Idálio J. Viegas, Henrique Machado, Lara López-Escobar, Luísa M. Figueiredo
Publicado en: Biomedical Journal, 2024, ISSN 0346-251X
Editor: Pergamon Press Ltd.
DOI: 10.1101/2024.02.23.581781

Continuous distribution of cancer cells in the cell cycle unveiled by AI-segmented imaging of 37,000 HeLa FUCCI cells

Autores: Hamid Cheraghi, Kinga Dóra Kovács, Inna Székács, Robert Horvath, Bálint Szabó
Publicado en: Heliyon, Edición Volume 10, Edición 9, 2024, ISSN 2405-8440
Editor: Londen: Elsevier Ltd.
DOI: 10.1016/j.heliyon.2024.e30239

The troubled puberty of malaria parasites

Autores: Jonas Gockel, Till S. Voss, Richárd Bártfai
Publicado en: Trends in Parasitology, Edición Volume 39, Edición 3, 2023, Página(s) 155-157, ISSN 1097-4172
Editor: Cell Press
DOI: 10.1016/j.pt.2023.01.006

Slow growing behavior in African trypanosomes during adipose tissue colonization

Autores: Sandra Trindade, Mariana de Niz, Mariana Costa-Sequeira, Tiago Bizarra-Rebelo, Fábio Bento, Mario Dejung, Marta Valido Narciso, Lara López-Escobar, João Ferreira, Falk Butter, Frédéric Bringaud, Erida Gjini, Luisa M. Figueiredo
Publicado en: Nature Communications, Edición 13, Article number: 7548, 2022, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-022-34622-w

A systematic quantitative approach comprehensively defines domain-specific functional pathways linked to Schizosaccharomyces pombe heterochromatin regulation

Autores: Abubakar Muhammad, Zsuzsa Sarkadi, Thomas van Emden, Agnisrota Mazumder, Matias Capella, Gergely Fekete, Vishnu N. Suma Sreechakram, Bassem Al-Sady, Balázs Papp, Ramón Ramos Barrales, Sigurd Braun
Publicado en: bioRxiv, 2024
Editor: Cold Spring Harbor Laboratory
DOI: 10.1101/2024.02.13.579970

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