What makes a successfull pathogen? Understanding the impact of cell-to-cell heterogeneity in chromatin structure on infection and adaptation

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Pubblicazioni

The molecular grammar of protein disorder guiding genome-binding locations

Autori: Felix Jonas, Miri Carmi, Beniamin Krupkin, Joseph Steinberger, Sagie Brodsky, Tamar Jana, Naama Barkai
Pubblicato in: Nucleic Acids Research, Numero Vol. 51, Numero 10, 2023, Pagina/e 4831-4844, ISSN 0305-1048
Editore: Oxford University Press
DOI: 10.1093/nar/gkad184

Cell-to-Cell Heterogeneity in Trypanosomes

Autori: Vanessa Luzak, Lara López-Escobar, T. Nicolai Siegel, Luisa M. Figueiredo
Pubblicato in: Annual Review of Microbiology, Numero 75/1, 2021, Pagina/e 107-128, ISSN 0066-4227
Editore: Annual Reviews, Inc.
DOI: 10.1146/annurev-micro-040821-012953

The inner nuclear membrane protein Lem2 coordinates RNA degradation at the nuclear periphery

Autori: Lucía Martín Caballero, Matías Capella, Ramón Ramos Barrales, Nikolay Dobrev, Thomas van Emden, Yasuhiro Hirano, Vishnu N. Suma Sreechakram, Sabine Fischer-Burkart, Yasuha Kinugasa, Alicia Nevers, Mathieu Rougemaille, Irmgard Sinning, Tamás Fischer, Yasushi Hiraoka & Sigurd Braun
Pubblicato in: Nature Structural & Molecular Biology, Numero Vol. 29, 2022, Pagina/e 910-921, ISSN 1545-9993
Editore: Nature Publishing Group
DOI: 10.1038/s41594-022-00831-6

The 3-phosphoinositide-dependent protein kinase 1 is an essential upstream activator of protein kinase A in malaria parasites

Autori: Eva Hitz, Natalie Wiedemar, Armin Passecker, Beatriz A. S. Graça, Christian Scheurer, Sergio Wittlin, Nicolas M. B. Brancucci, Ioannis Vakonakis, Pascal Mäser, Till S. Voss
Pubblicato in: PLoS Biology, Numero 19(12), 2021, ISSN 1545-7885
Editore: Plos
DOI: 10.1371/journal.pbio.3001483

A genome-wide map of DNA replication at single-molecule resolution in the malaria parasite Plasmodium falciparum

Autori: Francis Isidore Garcia Totañes, Jonas Gockel, Sarah E. Chapman, Richárd Bártfai, Michael A. Boemo, Catherine J. Merrick
Pubblicato in: Nucleic Acids Research, Numero Volume 51, Numero 6, 2023, Pagina/e 2709-2724, ISSN 0305-1048
Editore: Oxford University Press
DOI: 10.1093/nar/gkad093

m6A landscape is more pervasive when Trypanosoma brucei exits the cell cycle

Autori: Lúcia Serra, Sara Silva Pereira, Idálio J. Viegas, Henrique Machado, Lara López-Escobar, Luísa M. Figueiredo
Pubblicato in: Biomedical Journal, 2024, ISSN 0346-251X
Editore: Pergamon Press Ltd.
DOI: 10.1101/2024.02.23.581781

Continuous distribution of cancer cells in the cell cycle unveiled by AI-segmented imaging of 37,000 HeLa FUCCI cells

Autori: Hamid Cheraghi, Kinga Dóra Kovács, Inna Székács, Robert Horvath, Bálint Szabó
Pubblicato in: Heliyon, Numero Volume 10, Numero 9, 2024, ISSN 2405-8440
Editore: Londen: Elsevier Ltd.
DOI: 10.1016/j.heliyon.2024.e30239

The troubled puberty of malaria parasites

Autori: Jonas Gockel, Till S. Voss, Richárd Bártfai
Pubblicato in: Trends in Parasitology, Numero Volume 39, Numero 3, 2023, Pagina/e 155-157, ISSN 1097-4172
Editore: Cell Press
DOI: 10.1016/j.pt.2023.01.006

Slow growing behavior in African trypanosomes during adipose tissue colonization

Autori: Sandra Trindade, Mariana de Niz, Mariana Costa-Sequeira, Tiago Bizarra-Rebelo, Fábio Bento, Mario Dejung, Marta Valido Narciso, Lara López-Escobar, João Ferreira, Falk Butter, Frédéric Bringaud, Erida Gjini, Luisa M. Figueiredo
Pubblicato in: Nature Communications, Numero 13, Article number: 7548, 2022, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-022-34622-w

A systematic quantitative approach comprehensively defines domain-specific functional pathways linked to Schizosaccharomyces pombe heterochromatin regulation

Autori: Abubakar Muhammad, Zsuzsa Sarkadi, Thomas van Emden, Agnisrota Mazumder, Matias Capella, Gergely Fekete, Vishnu N. Suma Sreechakram, Bassem Al-Sady, Balázs Papp, Ramón Ramos Barrales, Sigurd Braun
Pubblicato in: bioRxiv, 2024
Editore: Cold Spring Harbor Laboratory
DOI: 10.1101/2024.02.13.579970

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