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Dissecting the regulatory logic of poised enhancers

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Publications

The chromatin, topological and regulatory properties of pluripotency-associated poised enhancers are conserved in vivo

Author(s): Giuliano Crispatzu, Rizwan Rehimi, Tomas Pachano, Tore Bleckwehl, Sara Cruz-Molina, Cally Xiao , Esther Mahabir, Hisham Bazzi, Alvaro Rada-Iglesias
Published in: Nature Communications, 2021, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-021-24641-4

Orphan CpG islands amplify poised enhancer regulatory activity and determine target gene responsiveness

Author(s): Tomas Pachano, Víctor Sánchez-Gaya, Thais Ealo, Maria Mariner-Faulí, Tore Bleckwehl, Helena G Asenjo, Patricia Respuela, Sara Cruz-Molina, María Muñoz-San Martín , Endika Haro, Wilfred F J van IJcken, David Landeira, Alvaro Rada-Iglesias
Published in: Nature Genetics, 2021, ISSN 1061-4036
Publisher: Nature Publishing Group
DOI: 10.1038/s41588-021-00888-x