Human Exposome Assessment Platform

CORDIS bietet Links zu öffentlichen Ergebnissen und Veröffentlichungen von HORIZONT-Projekten.

Links zu Ergebnissen und Veröffentlichungen von RP7-Projekten sowie Links zu einigen Typen spezifischer Ergebnisse wie Datensätzen und Software werden dynamisch von OpenAIRE abgerufen.

Leistungen

Sensor pilot Documentation

Prior to the enrollment of the first subject, we will submit (i) Final version of study protocol as submitted to regulators/ethics committee(s), (ii) Registration number of clinical study in a WHO-or ICMJE- approved registry (with the possibility to post results), (iii) Approvals (ethics committees and national competent authority if applicable) required for invitation/enrolment of first subject in at least one clinical centre.

Exposure DNAme signatures

A list of CpGs which collectively change as a function of exposure to a specific conditionfactor and which can be used to define an index eg smokingindex will be provided

List of Working Groups and ToR for the WGs - EXPANSE/HEAP

A first set of working groups will be made and Term of Reference for the WGs will be specified including the selection of work group leaders coleads and members

Reference architecture

Document describing the reference architecture for Information Commons and technical requirements.

Secure platform and recruitment

Recruitment using secure electronic customer receipts analysis platform commenced Plan to recruit 10000 individuals

Report on secure data platform

Documentation of the secure data platform and its integration into HEAP.

Ageing DNAme signatures

A list of CpGs which collectively change as a function of age eg general age signature stem cell polycombgroup target signature replicative age etc will be provided

Report on databases mapped

Report on databases mapped and how they contribute to the proper implementation of the GDPR and national legislation. Databases are mapped according to their legal bases, relevant other GDPR issues and options for 'further use' for research. The dataflows for the research, data protection by design, data security at the various in-between phases, controller-processor agreements and the final database(s) are mapped. The report will include recommendations for possible improvements from a GDPR perspective and include a DPIA on processing of data on the CSC platform.

Handover document to next coordinating team – EXPANSE/HEAP

Document summarising network activities and ongoing activities to facilitate a smooth transition to the next team. This document will include concise reports from working groups.

Report on consumer receipts data and sample-derived data

Special report about how data from a consenting cohort providing data from consumer receipts may be used for public health in an ethically and data protection compliant way In that context also a DPIA will be performed

Knowledge and information sharing - Phase I

Report from activities implemented and resources developed in order to support data providers within the consortium to effectively upload data to HEAP

Report on implementation for research use cases

Report describing implementation and experiences from HEAP research use cases.

Report on consumer data

Scientific report on consumer data’s potential as a tool for lifestyle assessment including methodology needed to facilitate evidence-based consumer-friendly lifestyle advice. Report on potential exposure to nutrients, chemicals, and additives as accessed by consumer data, and association to health-related outcomes, or absence of such outcomes.

Integrated personal exposome and metabolomics profile

A complete report of personal exposome and metabolomics profile, and how these factors may impact the health of the participant, and potential risk for certain diseases. The report may be integrated with findings from WP8 and WP9 to provide a fuller vision of the health of a particular participant.

An established setting for evaluation

An established setting for evaluation of the extent of exposures to the populations in 2 EU countries with consecutive time-windows (continuous population-based enrolment ongoing for 10 to 35 years) allows access to bio-specimens taken at any calendar year of interest for evaluating impact of naturally occurring and iatrogenic exposures to the population. This deliverable is linked to task 3.2.

Knowledge and information-sharing plan

Report from the mapping of key topics to be addressed as well as the mapping of target audiences including a plan for the elaboration and implementation of learning and informational resources and events

Data availability confirmation

An explicit confirmation that the data used in the project is publicly available and can be freely used for the purposes of the project. (KI, M6)

Ontology and semantic metadata

Ontology and semantic metadata for metagenomic profiles and tools for NGS data management

Advanced statistics analysis on Finnish Maternity Cohort and Swedish Cervical Screening Cohort

Test the methods and decision support module implemented in Task 6.6 on the Finnish Maternity Cohort and the Swedish Cervical Screening Cohort.

HEAP Data Warehouse

Complete configuration of Hopswork for the requirements of HEAP including data management, analysis, and sharing and the integration with IC and analysis providers. We will create a Hopsworks HEAP repo in GitHub.

Demonstrator of integration of wearable sensors

Data from the pilot for testing the workflow for data streaming from to data analysis in close collaboration with WP5.

HEAP Knowledge Engine

In collaboration with WP8, WP9, WP3, WP4, implementation and integration of deep learning and the main analysis pipelines provided by the partners. Updating of Hopsworks HEAP repo in GitHub.

Improved wearable PEMs

A wearable and durable PEM that enables everyday monitoring of environmental exposure at the personal level and provides data for streaming and real-time monitoring implemented by WP6.

AI based alignment free (agnostic) taxonomic classification

AI based alignment free (agnostic) taxonomic classification algorithm able to classify virus-related sequences in metagenomic sequencing datasets, fully integrated in the bioinformatics workflow from D9.1.

FAIR Toolbox and BYOD workshops

FAIR Toolbox and BYOD workshops - This deliverable provides a Findable, Accessible, Interoperable and Reusable and Bring Your Own Data (BYOD) workshops where HEAP data provider will get a hands-on training (hackathon) and can improve and evaluate the interoperability and FAIRness of their data sets.

Formalise Knowledge in HEAP

A continuously expanding, comprehensive, population-level exposure assessment over time based on high-throughput laboratory analyses of the consecutive sample sets. In collaboration with WP6, this data will be formalised to be integrated into the HEAP IC and Data & Feature Warehouse.

Massively parallel Bioinformatics pipeline

Bioinformatics pipeline, an ecosystem of bioinformatics tools, for complete analysis of metagenomic data generated from human biospecimens using NGS technologies, optimised for Hadoop and HPC ecosystems and, in collaboration with WP6, integrated to be used through the graphical user interface of the HEAP platform.

Exposome and metabolomics analysis pipelines

Analysis pipelines for both exposome and metabolomics will be streamlined for integration with WP8 and WP9, and implementation with WP6.

Searchable database

Searchable database with data on all the donors (age, sex) and registry-derived data on all the disease endpoints that have developed in the three cohorts. The software for the database is developed by partner 2 (SSI) and allows integrity-assured, yet flexible searches that will allow easy design of maximally informative research studies based on the biospecimens and data from these cohorts. In Collaboration with WP10, data from the database will be available to the IC.

Bacterial and viral metagenomics.

High performance bioinformatics workflow for mining bacterial de novo analysis of viral genomes in metagenomic sequencing datasets genomes in NGS metagenomic sequencing datasets.

Online platform and tools

An online platform combining informational and educational material, enriched with learning management and newsletter functionalities.

Demonstrator of the data analysis and data sharing on HEAP

This deliverable will provide a test environment for curating, uploading, managing, analysing and sharing data. Partners providing data and analysis pipelines will use the environment to produce the first results from the cohorts. Shareable data and results will available through the Data & Feature Warehouse.

Project Website

The HEAP website with information on exposome research in general and the project in particular, with sections targeted either to the scientific community or to the general public.

Network website - HEAP

Website with network activities and links to all individual network websites.

Data management plan

Data Management Plan - This deliverable will provide the governance and HEAP policies regarding the access, management and sharing of all the used and produced data during and after the project is completed. The plan will cover the generation of metadata from the different data sources of the project including all the cohorts, the raw and processed data and the results to be stored, preserved and shared for future exposome research.

Veröffentlichungen

Challenges and recommendations for the translation of biomarkers of aging

Autoren: null null, Chiara M. S. Herzog, Ludger J. E. Goeminne, Jesse R. Poganik, Nir Barzilai, Daniel W. Belsky, Joe Betts-LaCroix, Brian H. Chen, Michelle Chen, Alan A. Cohen, Steven R. Cummings, Peter O. Fedichev, Luigi Ferrucci, Alexander Fleming, Kristen Fortney, David Furman, Vera Gorbunova, Albert Higgins-Chen, Lee Hood, Steve Horvath, Jamie N. Justice, Douglas P. Kiel, George A. Kuchel, Jessica Las
Veröffentlicht in: Nature Aging, Ausgabe 4, 2024, Seite(n) 1372-1383, ISSN 2662-8465
Herausgeber: Springer Science and Business Media LLC
DOI: 10.1038/s43587-024-00683-3

Functionally enriched epigenetic clocks reveal tissue-specific discordant aging patterns in individuals with cancer

Autoren: Chiara M. S. Herzog, Elisa Redl, James Barrett, Sepideh Aminzadeh-Gohari, Daniela D. Weber, Julia Tevini, Roland Lang, Barbara Kofler, Martin Widschwendter
Veröffentlicht in: Communications Medicine, Ausgabe 5, 2025, ISSN 2730-664X
Herausgeber: Springer Science and Business Media LLC
DOI: 10.1038/s43856-025-00739-4

Prostate Cancer Testing Between Screening Rounds: Evidence from the STHLM3-MRI Trial

Autoren: Daniela Skalt, Ting Chen, Ahmad Abbadi, Anna Lantz, Andrea Discacciati, Martin Eklund, Mark Clements, Tobias Nordström, Shuang Hao
Veröffentlicht in: European Urology Oncology, 2025, ISSN 2588-9311
Herausgeber: Elsevier BV
DOI: 10.1016/j.euo.2025.05.015

Provenance of specimen and data – A prerequisite for AI development in computational pathology

Autoren: Markus Plass, Rudolf Wittner, Petr Holub, Francesca Frexia, Cecilia Mascia, Matej Gallo, Heimo Müller, Jörg Geiger
Veröffentlicht in: New Biotechnology, 2023, ISSN 1871-6784
Herausgeber: Elsevier BV
DOI: 10.1016/j.nbt.2023.09.006

Improving Species Level‐taxonomic Assignment from 16S rRNA Sequencing Technologies

Autoren: David Bars‐Cortina, Ferran Moratalla‐Navarro, Ainhoa García‐Serrano, Núria Mach, Lois Riobó‐Mayo, Jordi Vea‐Barbany, Blanca Rius‐Sansalvador, Silvia Murcia, Mireia Obón‐Santacana, Victor Moreno
Veröffentlicht in: Current Protocols, Ausgabe 3, 2024, ISSN 2691-1299
Herausgeber: Wiley
DOI: 10.1002/cpz1.930

Overweight in childhood and consumer purchases in a Danish cohort

Autoren: Kathrine Kold Sørensen, Mikkel Porsborg Andersen, Frederik Trier Møller, Rikke Wiingreen, Marcella Broccia, Emil L. Fosbøl, Bochra Zareini, Thomas Alexander Gerds, Christian Torp-Pedersen
Veröffentlicht in: PLOS ONE, Ausgabe 19, 2024, Seite(n) e0297386, ISSN 1932-6203
Herausgeber: Public Library of Science
DOI: 10.1371/journal.pone.0297386

Comparison between 16S rRNA and shotgun sequencing in colorectal cancer, advanced colorectal lesions, and healthy human gut microbiota

Autoren: David Bars-Cortina, Elies Ramon, Blanca Rius-Sansalvador, Elisabet Guinó, Ainhoa Garcia-Serrano, Núria Mach, Olfat Khannous-Lleiffe, Ester Saus, Toni Gabaldón, Gemma Ibáñez-Sanz, Lorena Rodríguez-Alonso, Alfredo Mata, Ana García-Rodríguez, Mireia Obón-Santacana, Victor Moreno
Veröffentlicht in: BMC Genomics, Ausgabe 25, 2024, ISSN 1471-2164
Herausgeber: BioMed Central
DOI: 10.1186/s12864-024-10621-7

Assessing household lifestyle exposures from consumer purchases, the My Purchases cohort

Autoren: Frederik T. Møller, Thor Grønborg Junker, Kathrine Kold Sørensen, Caroline Eves, Jan Wohlfahrt, Joakim Dillner, Christian Torp-Pedersen, Bartlomiej Wilkowski, Steven Chong, Tune H. Pers, Victor Yakimov, Heimo Müller, Steen Ethelberg & Mads Melbye
Veröffentlicht in: Scientific Reports, 2023, ISSN 2045-2322
Herausgeber: Nature Publishing Group
DOI: 10.1038/s41598-023-47534-6

BIBBOX, a FAIR toolbox and App Store for life science research

Autoren: Heimo Müller, Catarina Lopes-Dias, Petr Holub, Markus Plass, Emilian Jungiwrth, Robert Reihs, Paul R. Torke, Apostolos Malatras, Anouk Berger, Heather Coombs, Joakim Dillner and Roxana Merino-Martinez
Veröffentlicht in: New Biotechnology, 2023, ISSN 1871-6784
Herausgeber: Elsevier BV
DOI: 10.1016/j.nbt.2023.06.001

Susceptibility to hormone-mediated cancer is reflected by different tick rates of the epithelial and general epigenetic clock

Autoren: James E. Barrett; Chiara Herzog; Yoo-Na Kim; Thomas E. Bartlett; Allison Jones; Iona Evans; David Cibula; Michal Zikan; Line Bjørge; Nadia Harbeck; Nicoletta Colombo; Sacha J. Howell; Angelique Flöter Rådestad; Kristina Gemzell-Danielsson; Martin Widschwendter
Veröffentlicht in: Genome Biology, Ausgabe 27, 2022, Seite(n) 52, ISSN 1474-760X
Herausgeber: BMC SpringerNature
DOI: 10.1186/s13059-022-02603-3

Cervical cancer microbiome analysis: comparing HPV 16 and 18 with other HPV types

Autoren: Maire Hidjo, Dhananjay Mukhedkar, Collen Masimirembwa, Jiayao Lei, Laila Sara Arroyo Mühr
Veröffentlicht in: Scientific Reports, Ausgabe 14, 2024, ISSN 2045-2322
Herausgeber: Nature Publishing Group
DOI: 10.1038/s41598-024-73317-8

Toward Human–AI Interfaces to Support Explainability and Causability in Medical AI

Autoren: Andreas Holzinger; Heimo Müller
Veröffentlicht in: Computer, Ausgabe 28, 2021, Seite(n) 78-86, ISSN 1558-0814
Herausgeber: IEEE Computer Society
DOI: 10.1109/mc.2021.3092610

The Ten Commandments of Ethical Medical AI

Autoren: H. Muller, M. Mayrhofer, E. Van Veen and A. Holzinger
Veröffentlicht in: Computer, Ausgabe 54, 2021, Seite(n) 119-123, ISSN 1558-0814
Herausgeber: IEEE Computer Society
DOI: 10.1109/mc.2021.3074263

Spatio-temporal variation in prostate cancer testing in Stockholm: A population-based study

Autoren: Balram Rai, Tobias Nordström, Anna Lantz, Rolf Lyneborg Lund, Ralf Kuja-Halkola, Marta Rado, Sara Öberg, Shuang Hao, Xiaoyang Du, Mark Clements
Veröffentlicht in: PLOS ONE, Ausgabe 19, 2024, Seite(n) e0308254, ISSN 1932-6203
Herausgeber: Public Library of Science
DOI: 10.1371/journal.pone.0308254

Explainability and causability for artificial intelligence-supported medical image analysis in the context of the European In Vitro Diagnostic Regulation

Autoren: Heimo Müller, Andreas Holzinger, Markus Plass, Luka Brcic, Cornelia Stumptner, Kurt Zatloukal
Veröffentlicht in: New Biotechnology, Ausgabe 70, 2022, Seite(n) 67-72, ISSN 1871-6784
Herausgeber: Elsevier BV
DOI: 10.1016/j.nbt.2022.05.002

Cervical cancer screening using DNA methylation triage in a real-world population

Autoren: Lena Schreiberhuber, James E. Barrett, Jiangrong Wang, Elisa Redl, Chiara Herzog, Charlotte D. Vavourakis, Karin Sundström, Joakim Dillner, Martin Widschwendter
Veröffentlicht in: Nature Medicine, Ausgabe 30, 2024, Seite(n) 2251-2257, ISSN 1078-8956
Herausgeber: Nature Publishing Group
DOI: 10.1038/s41591-024-03014-6

Creating personas for exposome research: the experience from the HEAP project

Autoren: Heather Coombs; Tracy Wootton; Joakim Dillner; Heimo Müller; Anouk Berger; Zisis Kozlakidis
Veröffentlicht in: Open Research Europe, 2023, ISSN 2732-5121
Herausgeber: EU
DOI: 10.12688/openreseurope.15474.1

HPV-induced host epigenetic reprogramming is lost upon progression to high-grade cervical intraepithelial neoplasia

Autoren: Herzog C, Vavourakis CD, Barrett JE, Karbon G, Villunger A, Wang J, Sundström K, Dillner J, Widschwendter M
Veröffentlicht in: International Journal of Cancer, 2023, ISSN 0020-7136
Herausgeber: John Wiley & Sons Inc.
DOI: 10.1002/ijc.34477

The European health data space: Too big to succeed?

Autoren: Luca Marelli , Marthe Stevens , Tamar Sharon , Ine Van Hoyweghen , Martin Boeckhout , Ilaria Colussi , Alexander Degelsegger-M ́ arquez , Seliem El-Sayed , Klaus Hoeyer , Robin van Kessel , Dorota Krekora Zaj Î ac , Mihaela Matei , Sara Roda , Barbara Prainsack , Irene Schl ̈ under , Mahsa Shabani , Tom Southerington
Veröffentlicht in: Health Policy, 2023, ISSN 0168-8510
Herausgeber: Elsevier BV
DOI: 10.1016/j.healthpol.2023.104861

Joint controllers in large research consortia: a funnel model to distinguish controllers in the sense of the GDPR from other partners in the consortium

Autoren: Evert-Ben Van Veen, Martin Boeckhout, Irene Schlünder, Jan Willem Boiten, Vasco Dias
Veröffentlicht in: Open Research Europe, Ausgabe 2, 2024, Seite(n) 80, ISSN 2732-5121
Herausgeber: F1000 Research Ltd
DOI: 10.12688/openreseurope.14825.2

Joint controllers in large research consortia: a funnel model to distinguish controllers in the sense of the GDPR from other partners in the consortium

Autoren: Evert-Ben Van Veen; Martin Boeckhout; Irene Schlünder; Jan Willem Boiten; Vasco Dias
Veröffentlicht in: Open Research Europe, Ausgabe 28, 2022, ISSN 2732-5121
Herausgeber: European Comission
DOI: 10.12688/openreseurope.14825.1

Ecological diversity profiles of non-vaccine-targeted HPVs after gender-based community vaccination efforts

Autoren: Ville N. Pimenoff, Penelope Gray, Karolina Louvanto, Tiina Eriksson, Camilla Lagheden, Anna Söderlund-Strand, Joakim Dillner, Matti Lehtinen
Veröffentlicht in: Cell Host & Microbes, 2023, ISSN 1931-3128
Herausgeber: Cell Press
DOI: 10.1016/j.chom.2023.10.001

Technical and biological sources of unreliability of Infinium probes on Illumina methylation microarrays

Autoren: Tatiana Nazarenko, Charlotte Dafni Vavourakis, Allison Jones, Iona Evans, Lena Schreiberhuber, Christine Kastner, Isma Ishaq-Parveen, Elisa Redl, Anthony W. Watson, Kirsten Brandt, Clive Carter, Alexey Zaikin, Chiara Maria Stella Herzog, Martin Widschwendter
Veröffentlicht in: Clinical Epigenetics, Ausgabe 16, 2024, ISSN 1868-7083
Herausgeber: Springer Science and Business Media LLC
DOI: 10.1186/s13148-024-01739-2

HPV-KITE: sequence analysis software for rapid HPV genotype detection

Autoren: Marek Nowicki, Magdalena Mroczek, Dhananjay Mukhedkar, Piotr Bała, Ville Nikolai Pimenoff, Laila Sara Arroyo Mühr
Veröffentlicht in: Briefings in Bioinformatics, Ausgabe 26, 2025, ISSN 1467-5463
Herausgeber: Oxford University Press
DOI: 10.1093/bib/bbaf155

Is human oversight to AI systems still possible?

Autoren: Andreas Holzinger, Kurt Zatloukal, Heimo Müller
Veröffentlicht in: New Biotechnology, Ausgabe 85, 2025, Seite(n) 59-62, ISSN 1871-6784
Herausgeber: Elsevier BV
DOI: 10.1016/j.nbt.2024.12.003

Cost-effectiveness of Prostate Cancer Screening Using Magnetic Resonance Imaging or Standard Biopsy Based on the STHLM3-MRI Study

Autoren: Shuang Hao, Andrea Discacciati, Martin Eklund, Emelie Heintz, Ellinor Östensson, K. Miriam Elfström, Mark S. Clements, Tobias Nordström
Veröffentlicht in: JAMA Oncology, Ausgabe 9, 2023, Seite(n) 88, ISSN 2374-2437
Herausgeber: American Medical Association (AMA)
DOI: 10.1001/jamaoncol.2022.5252

Red blood cell alloimmunization in myelodysplastic syndromes: Associations with sex, DAT‐positivity, and increased transfusion needs

Autoren: Jenny Rydén; Mark Clements; Agneta Wikman; Eva Hellström‐Lindberg; Gustaf Edgren; Petter Höglund
Veröffentlicht in: Transfusion, 2023, ISSN 2080-1505
Herausgeber: Wiley
DOI: 10.1111/trf.17562

Noncancer-Related Mortality in Randomized Clinical Trials

Autoren: Jiayao Lei, Yunyang Deng, Mark Clements, Stephen Duffy, Peter Sasieni
Veröffentlicht in: JAMA Network Open, Ausgabe 8, 2025, Seite(n) e2526990, ISSN 2574-3805
Herausgeber: American Medical Association (AMA)
DOI: 10.1001/jamanetworkopen.2025.26990

Personas for Artificial Intelligence (AI) an Open Source Toolbox

Autoren: Andreas Holzinger; Michaela Kargl; Bettina Kipperer; Peter Regitnig; Markus Plass; Heimo Muller
Veröffentlicht in: IEEE Access, Ausgabe 27, 2022, Seite(n) 23732-23747, ISSN 2169-3536
Herausgeber: Institute of Electrical and Electronics Engineers Inc.
DOI: 10.1109/access.2022.3154776

Metagenomic Study Reveals Phage–Bacterial Interactome Dynamics in Gut and Oral Microbiota in Pancreatic Diseases

Autoren: Laura Vilà-Quintana, Esther Fort, Laura Pardo, Maria T. Albiol-Quer, Maria Rosa Ortiz, Montserrat Capdevila, Anna Feliu, Anna Bahí, Marc Llirós, Adelaida García-Velasco, Mireia Morell Ginestà, Berta Laquente, Débora Pozas, Victor Moreno, Librado Jesús Garcia-Gil, Eric Jeffrey Duell, Ville Nikolai Pimenoff, Robert Carreras-Torres, Xavier Aldeguer
Veröffentlicht in: International Journal of Molecular Sciences, Ausgabe 25, 2025, Seite(n) 10988, ISSN 1422-0067
Herausgeber: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms252010988

Explainability and causability in digital pathology

Autoren: Markus Plass; Michaela Kargl; Tim‐Rasmus Kiehl; Peter Regitnig; Christian Geißler; Theodore Evans; Norman Zerbe; Rita Carvalho; Andreas Holzinger; Heimo Müller
Veröffentlicht in: The Journal of Pathology Clinical Research, Ausgabe 22, 2023, ISSN 2056-4538
Herausgeber: Wiley
DOI: 10.1002/cjp2.322

Meta-Analysis and Validation of a Colorectal Cancer Risk Prediction Model Using Deep Sequenced Fecal Metagenomes.

Autoren: Obón-Santacana M, Mas-Lloret J, Bars-Cortina D, Criado-Mesas L, Carreras-Torres R, Díez-Villanueva A, Moratalla-Navarro F, Guinó E, Ibáñez-Sanz G, Rodríguez-Alonso L, Mulet-Margalef N, Mata A, García-Rodríguez A, Duell EJ, Pimenoff VN, Moreno V.
Veröffentlicht in: Cancers, 2022, ISSN 2072-6694
Herausgeber: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers14174214

Cigarette Smoking and E-cigarette Use Induce Shared DNA Methylation Changes Linked to Carcinogenesis

Autoren: Chiara Herzog, Allison Jones, Iona Evans, Janhavi R. Raut, Michal Zikan, David Cibula, Andrew Wong, Hermann Brenner, Rebecca C. Richmond, Martin Widschwendter
Veröffentlicht in: Cancer Research, Ausgabe 84, 2024, Seite(n) 1898-1914, ISSN 0008-5472
Herausgeber: American Association for Cancer Research
DOI: 10.1158/0008-5472.can-23-2957

Assessment of bacterial and viral gut communities in healthy and tumoral colorectal tissue using <scp>RNA</scp> and <scp>DNA</scp> deep sequencing

Autoren: Ainhoa Garcia‐Serrano; Dhananjay Mukhedkar; Emilie Hultin; Ulla Rudsander; Yvonne Wettergren; Agustín Enrique Ure; Joakim Dillner; Laila Sara Arroyo‐Mühr
Veröffentlicht in: Cancer Medicine, Ausgabe 17, 2023, ISSN 2045-7634
Herausgeber: Wiley
DOI: 10.1002/cam4.6483

Influence of Genetics, Immunity and the Microbiome on the Prognosis of Inflammatory Bowel Disease (IBD Prognosis Study): the protocol for a Copenhagen IBD Inception Cohort Study

Autoren: Attauabi M, Madsen GR, Bendtsen F, Wewer AV, Wilkens R, Ilvemark J, Vladimirova N, Jensen AB, Jensen FK, Hansen SB, Siebner HR, Nielsen YJW, Møller JM, Thomsen HS, Thomsen SF, Ingels HAS, Theede K, Boysen T, Bjerrum JT, Jakobsen C, Dorn-Rasmussen M, Jansson S, Yao Y, Burian EA, Møller FT, Fana V, Wiell C, Terslev L, Østergaard M, Bertl K, Stavropoulos A, Seidelin JB, Burisch J.
Veröffentlicht in: BMJ Open, Ausgabe 12(6), 2022, Seite(n) e055779, ISSN 2044-6055
Herausgeber: BMJ Publishing Group
DOI: 10.1136/bmjopen-2021-055779

AI for life: Trends in artificial intelligence for biotechnology

Autoren: Andreas Holzinger, Katharina Keiblinger, Petr Holub, Kurt Zatloukal, Heimo Müller
Veröffentlicht in: New Biotechnology, 2023, ISSN 1871-6784
Herausgeber: Elsevier BV
DOI: 10.1016/j.nbt.2023.02.001

Using HPV-meta for human papillomavirus RNA quality detection

Autoren: Agustin Ure; Dhananjay Mukhedkar; Laila Sara Arroyo Mühr
Veröffentlicht in: Scientific Reports, Ausgabe 10, 2022, Seite(n) 13058, ISSN 2045-2322
Herausgeber: Nature Publishing Group
DOI: 10.1038/s41598-022-17318-5

Seroepidemiological assessment of the spread of SARS-CoV-2 among 25 and 28 year-old adult women in Finland between March 2020-June 2022

Autoren: Penelope Gray, Tiina Eriksson, Lovisa Skoglund, Camilla Lagheden, Ceke Hellström, Elisa Pin, Anna Suomenrinne-Nordvik, Ville N. Pimenoff, Peter Nilsson, Joakim Dillner, Matti Lehtinen
Veröffentlicht in: PLOS ONE, Ausgabe 19, 2024, Seite(n) e0305285, ISSN 1932-6203
Herausgeber: Public Library of Science
DOI: 10.1371/journal.pone.0305285

Human exposome assessment platform

Autoren: Merino Martinez, R. (Roxana); Müller, H. (Heimo); Negru, S. (Stefan); Ormenisan, A. (Alex); Arroyo Mühr, L. S. (Laila Sara); Zhang, X. (Xinyue); Trier Møller, F. (Frederik); Clements, M. S. (Mark S.); Kozlakidis, Z. (Zisis); Pimenoff, V. N. (Ville N.); Wilkowski, B. (Bartlomiej); Boeckhout, M. (Martin); Öhman, H. (Hanna); Chong, S. (Steven); Holzinger, A. (Andreas); Lehtinen, M. (Matti); van V
Veröffentlicht in: Environmental Epidemiology, Ausgabe 13, 2021, Seite(n) e182, ISSN 2474-7882
Herausgeber: Wolters Kluwer
DOI: 10.1097/ee9.0000000000000182

The Swedish Cervical Screening Cohort

Autoren: Joakim Dillner, Laila Sara Arroyo Mühr, Sara Nordqvist Kleppe, Jiangrong Wang, Helena Andersson, Miriam Elfström, Roxana Merino, Karin Sundström
Veröffentlicht in: Scientific Data, Ausgabe 11, 2024, ISSN 2052-4463
Herausgeber: Springer Science and Business Media LLC
DOI: 10.1038/s41597-024-03519-2

Cohort profile: The Health, Food, Purchases and Lifestyle (SMIL) cohort – a Danish open cohort

Autoren: Kathrine Kold Sørensen, Mikkel Porsborg Andersen, Frederik Trier Møller, Caroline Eves, Thor Grønborg Junker, Bochra Zareini, Christian Torp-Pedersen
Veröffentlicht in: BMJ Open, Ausgabe 14, 2024, Seite(n) e078773, ISSN 2044-6055
Herausgeber: BMJ Publishing Group
DOI: 10.1136/bmjopen-2023-078773

A common framework for using and reporting consumer purchase data (CPD) in foodborne outbreak investigations in Europe

Autoren: Solveig Jore, Uffe Christian Braae, Frederik Trier Møller, Ingrid Friesema, Karthik Paranthaman, Katri Jalava, Nathalie Jourdan-DaSilva, Emma Löf, Moa Rehn, Steen Ethelberg
Veröffentlicht in: Infection Ecology & Epidemiology, Ausgabe 12, 2022, ISSN 2000-8686
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DOI: 10.1080/20008686.2021.2007828

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Herausgeber: ACM

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Herausgeber: ACM
DOI: 10.1145/3626246.3653389

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Veröffentlicht in: Proceedings of the 2020 USENIX Conference on Operational Machine Learning (OpML ’20), 2020, Seite(n) 13-15, ISBN 978-1-939133-15-1
Herausgeber: USENIX Association

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Veröffentlicht in: MedRxiv, 2025, ISSN 2475-9066
Herausgeber: openRxiv
DOI: 10.1101/2025.02.12.25322120

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Veröffentlicht in: MedRxiv, 2025, ISSN 2475-9066
Herausgeber: OpenRxiv
DOI: 10.1101/2025.05.19.25327897

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