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CORDIS

The implementation of Digital Mobile Mental Health in clinical care pathways: Towards person-centered care in psychiatry

CORDIS oferuje możliwość skorzystania z odnośników do publicznie dostępnych publikacji i rezultatów projektów realizowanych w ramach programów ramowych HORYZONT.

Odnośniki do rezultatów i publikacji związanych z poszczególnymi projektami 7PR, a także odnośniki do niektórych konkretnych kategorii wyników, takich jak zbiory danych i oprogramowanie, są dynamicznie pobierane z systemu OpenAIRE .

Rezultaty

IMMERSE public website and social media channels online (odnośnik otworzy się w nowym oknie)

In order to provide effective communication channels in order to inform the wider public on relevant project strategies and outcomes, a professional project website as well as social media channels will be created by the PMO which represent the consortium and the project online.

H - Requirement No. 11 (odnośnik otworzy się w nowym oknie)

'Midterm recruitment report' - Deliverable to be scheduled for the time point when 50% of the study population is expected to have been recruited. The report shall include an overview of recruited subjects by study site, potential recruiting problems and, if applicable, a detailed description of implemented and planned measures to compensate delays in the study subject recruitment.

Implementation Guide for interoperable data structures and interfaces (odnośnik otworzy się w nowym oknie)

WP3 will provide an implementation guide covering data structures, interfaces and an overall systems architecture for the DMMH platform. Open internationally adopted standards will be leveraged to ensure a sustainable implementation.

Set of basic statistics for direct implementation and visualization (odnośnik otworzy się w nowym oknie)

To obtain the basic statistics for visualization in WP2 and implemented in WP7 as well as to provide a solid baseline to which to compare the more advanced methods below WP4 will first focus on simple quick to compute statistically robust low standard error and easy to interpret statistics that describe distributional properties of the data and covariation between different feature dimensions These involve mean levels and variability of symptomscontextual factors over time as indicators of symptomcontext level and volatility and their mutual comparison to detect key personalized strengths and weaknesses Next they involve simple statistical time series tools for tracking symptoms and contextual factors and their correlations over time such as autoregressive movingaverage ARMA models or measures of mutual predictability Granger causality allowing to obtain basic insight into how symptomscontext variables cooccur or predict one another over time Finally to capture clinically significant moments of change or tipping points within the behavioural trajectories as they are unfolding across larger periods of time WP4 will use statistical change point detection techniques as developed in Leuven eg 138 and Mannheim eg 139 to detect reliable phase changes in mean levels as a function of for instance instalment of treatment or a particular change in treatment over time Methods for the correction of familywise error rate such as the HolmBonferroni procedure regularization techniques in model estimation and measures of outofsample prediction error will be adopted to minimize the risk of false positives to inform clinical decision making Outcomes from lowerlevel statistics and machine learning predictors will be summarized and delivered to the visualization platform in a clinically meaningful and accessible way

Report on Technology Context and Self-tracking Practices (odnośnik otworzy się w nowym oknie)

This report will consist of two papers one paper that reports the full results of the survey conducted in Task 51 and one paper that reports qualitative and quantitative findings from Task 52

Consolidated descriptions of interventions and implementation strategies for each of the participating sites (odnośnik otworzy się w nowym oknie)

Jointly with WP5 stakeholder engagement and other work packages ie WP24 WP6 we will first specify and optimize our strategies for implementation of the DMMH into practice The chosen implementation strategies will includea the DMMH information technology system which adheres to prevailing standards and regulations particularly regarding data protectionb an intervention manual consistent with the Template for Intervention Description and Replication Checklist training and support package for clinicians and services to facilitate the use of the DMMH with service usersc a wellbalanced package of tailored information counselling and reminders for service users to motivate and enable them to use the DMMHThese strategies will purposefully vary somewhat between the different clinical sites to address local requirements A detailed factual description of the DMMH intervention and implementation strategies as planned will be tailored to and optimized based on the requirements of each site Building on the work carried out in WP5 stakeholder engagement we will generate an a priori assessment of anticipated barriers and facilitators that influence implementation using the nonadoption abandonment scaleup spread and sustainability NASSS implementation science framework84 This has been specifically proposed for the implementation of novel technologies and will be used to optimize in close collaboration with WP5 the DMMH implementation strategies with regard to the 7 domains of this framework the condition or illness ie a mental disorder the technology the value proposition the adopter system comprising professional staff service users and informal caregivers the organizations the wider institutional and societal context and the interaction and mutual adaptation between all these domains over time Findings from the qualitative framework analysis method which has been designed to inform policy will directly inform tailoring of our implementation strategies to local requirements These will be further adopted and finalized based on findings from other work packages ie WP24 WP6 prior to the start of the cRCT

H - Requirement No. 12 (odnośnik otworzy się w nowym oknie)

For each clinical study the following documentsinformation must be submitted as a deliverable in one package prior to enrolment of first study subject i Final version of study protocol as submitted to regulatorsethics committees ii Registration number of clinical study in a WHO or ICMJEapproved registry with the possibility to post results iii Approvals ethics committees and national competent authority if applicable required for invitationenrolment of first subject in at least one clinical centre

Data Management Plan (odnośnik otworzy się w nowym oknie)

WP3 will provide a comprehensive data management plan based on the Horizon 2020 template DMP. The DMP will cover aspects of data acquisition, processing, quality control, data privacy aspects, metadata annotation, data deposition, licensing and usage policy according to the FAIR guiding principles. The DMP will provide as appendices an inventory of data elements processed during the project and a threat analysis regarding data privacy.

Algorithms and software environment for DTSM-based multi-modal big data integration (odnośnik otworzy się w nowym oknie)

Machine learning models developed in the present context need to efficiently exploit the multivariate and multimodal time series structure, and at the same time be able to adapt to the individual user, to make single subject inferences (e.g., 140, 141). Here, WP4 will infer deep time series models (DTSMs) based on recurrent neural networks (RNNs) from the individual app-based time series, as these are particularly suited to learn dynamical models of single subject behaviour, can adapt over time, and can, once trained on the (multimodal) measurements, be simulated to forecast and examine effects of environmental factors and interventions 25-27, 142. The DTSMs will be used to identify interpretable behavioural contingencies underlying changes in the subjects’ trajectories. By analysing trained model parameters, WP4 will be able to infer which behavioural variables, or multimodal variable combinations, and external factors are most strongly connected with each other. WP4 will further receive input from WP5 regarding missing data in the form of indicator, categorical, or count variables which may contain information about the mental health status or individual patterns of interaction with the mobile device, and can be explicitly included as response variables in the subject models.

Publikacje

The European Health Data Space: Too Big To Succeed? (odnośnik otworzy się w nowym oknie)

Autorzy: Marelli, L., Stevens, M., Sharon, T., Van Hoyweghen, I., Boeckhout, M., Colussi, I., ... & Southerington, T.
Opublikowane w: Health Policy, Numer 104861, 2023, ISSN 0922-3444
Wydawca: Elsevier
DOI: 10.1016/j.healthpol.2023.104861

Clinical benefits and challenges of ecological momentary assessment in individuals who self-injure and seek mental health treatment (odnośnik otworzy się w nowym oknie)

Autorzy: Rafaël A. Bonnier, Joanne R. Beames, Laurence Claes, Olivia J. Kirtley, Lena de Thurah, Jeroen D.M. Weermeijer, Lotte Uyttebroek, Mirthe Luijsmans, Inez Myin-Germeys, Glenn Kiekens
Opublikowane w: International Journal of Clinical and Health Psychology, Numer 25, 2025, Strona(/y) 100618, ISSN 1697-2600
Wydawca: Asociacion Espanola de Psicologia Conductual
DOI: 10.1016/j.ijchp.2025.100618

Preferences for an Experience Sampling Method–Based Tool as an Adjunct to Usual Treatment in Patients With Problem Substance Use: Qualitative Study (odnośnik otworzy się w nowym oknie)

Autorzy: Adam Kurilla, Natália Čavojská, Theresa Ikegwuonu, Marta Nemčíková, Julia CC Schulte-Strathaus, Lotte Uyttebroek, Joanne R Beames, Dagmar Breznoščáková, Daniel Dančík, Michal Hajdúk, Anton Heretik, Ľubomíra Izáková, Zuzana Katreniaková, Inez Myin-Germeys, Ján Pečeňák, Ulrich Reininghaus, Anita Schick, Maria Wolters
Opublikowane w: JMIR Formative Research, Numer 10, 2026, Strona(/y) e79510, ISSN 2561-326X
Wydawca: JMIR Publications Inc.
DOI: 10.2196/79510

Využitie mobilných technológií v liečbe psychických porúch: Projekt IMMERSE

Autorzy: Kurilla, A., Dančík, D., Čavojská, N., Izáková, Ľ., Pečeňák, J., Hajdúk, M., Heretik, A.
Opublikowane w: Psychiatria pre prax, Numer 23(4), 2022, Strona(/y) 163-166, ISSN 1335-9584
Wydawca: SOLEN Medical Education

Using Experience Sampling Methods to support clinical management of psychosis: The perspective of people with lived experience. (odnośnik otworzy się w nowym oknie)

Autorzy: de Thurah L, Kiekens G, Sips R, Teixeira A, Kasanova Z, Myin-Germeys I
Opublikowane w: Psychiatry Research, Numer 324, 2023, Strona(/y) 115207, ISSN 0165-1781
Wydawca: Elsevier BV
DOI: 10.1016/j.psychres.2023.115207

Can experience sampling self-monitoring tools promote the activation of clients in mental healthcare? A qualitative study (odnośnik otworzy się w nowym oknie)

Autorzy: Lena de Thurah, Jeroen Weermeijer, Lotte Uyttebroek, Martien Wampers, Rafaël Bonnier, Inez Myin-Germeys, Glenn Kiekens
Opublikowane w: Journal of Mental Health, Numer 34, 2025, Strona(/y) 645-653, ISSN 0963-8237
Wydawca: Brunner - Routledge (US)
DOI: 10.1080/09638237.2025.2478370

Strategies, processes, outcomes, and costs of implementing experience sampling-based monitoring in routine mental health care in four European countries: study protocol for the IMMERSE effectiveness-implementation study.

Autorzy: Reininghaus, U., Schwannauer, M., Barne, I., Beames, J.R., Bonnier, R.A., Brenner, M., Dančík, D., De Allegri, M., Di Folco, S., Dusterwitz, D., Hajduk, M., Heretik, A., Pecenak, J., Gugel, J., Izakova, L., Katreniakova, Z., Kiekens, G., Koppe, G., Kurilla, A., Marelli, L., Nagyova, I., Nguyen, H., Schulte-Strathaus, J., Sotomayor-Enriquez, K., Uyttebroek, L., Weermeijer, J.D.M., Wolters, M., We
Opublikowane w: BMC Psychiatry, 2024, ISSN 1471-244X
Wydawca: BioMed Central

A control theoretic approach to evaluate and inform ecological momentary interventions (odnośnik otworzy się w nowym oknie)

Autorzy: Janik Fechtelpeter, Christian Rauschenberg, Hamidreza Jalalabadi, Benjamin Boecking, Therese van Amelsvoort, Ulrich Reininghaus, Daniel Durstewitz, Georgia Koppe
Opublikowane w: International Journal of Methods in Psychiatric Research, Numer 33, 2024, ISSN 1049-8931
Wydawca: Whurr Publishers Ltd.
DOI: 10.1002/mpr.70001

The Experience Sampling Methodology as a Digital Clinical Tool for More Person-centred Mental Health Care: An Implementation Research Agenda

Autorzy: Myin-Germeys, I., Schick, A., Ganslandt, T., Hajdúk, M., Heretik, A., Van Hoyweghen, I., ... Reininghaus, U.
Opublikowane w: Psychological Medicine, 2024, ISSN 1469-8978
Wydawca: Psychological Medicine

Loneliness and social isolation in people with substance dependence (odnośnik otworzy się w nowym oknie)

Autorzy: Adam Kurilla, Daniel Dančík, Anton Heretik, Michal Hajdúk
Opublikowane w: Česká a slovenská psychiatrie, Numer 121, 2025, ISSN 1212-0383
Wydawca: Nakladatelske Stredisko CLSJE Purkyne
DOI: 10.48095/cccsp202510

Predicting clinical outcomes in a blended care intervention for early psychosis: Acceptance and Commitment Therapy in Daily-Life (ACT-DL) (odnośnik otworzy się w nowym oknie)

Autorzy: Rafaël Bonnier, Joanne Beames, Glenn Kiekens, Evelyne Van Aubel, Frederike Schirmbeck, Lieuwe de Haan, Machteld Marcelis, Mark van der Gaag, Ruud van Winkel, Therese Amelsvoort van, Thomas Vaessen, Ulrich Reininghaus, Ginette Lafit, Inez Myin-Germeys
Opublikowane w: Translational Psychiatry, 2023, ISSN 2158-3188
Wydawca: Nature Publishing Group
DOI: 10.21203/rs.3.rs-3573840/v1

Visualization of Experience Sampling Method Data in Mental Health: Qualitative Study of the Physicians’ Perspective in Germany (odnośnik otworzy się w nowym oknie)

Autorzy: Julia C C Schulte-Strathaus, Theresa Ikegwuonu, Anita Schick, Maria K Wolters, Lena de Thurah, Michal Hajdúk, Adam Kurilla, Inez Myin-Germeys, Glenn Kiekens, Jeroen D M Weermeijer, Joanne R Beames, Lotte Uyttebroek, Rafaël Bonnier, Iveta Nagyova, Dagmar Breznoščáková, Daniel Dančík, Koraima Sotomayor Enriquez, Islay Barne, Jessica Gugel, Ulrich Reininghaus, Michel Wensing, Charlotte Ullric
Opublikowane w: Journal of Medical Internet Research, Numer 27, 2025, Strona(/y) e72893-e72893, ISSN 1438-8871
Wydawca: Journal of medical Internet Research
DOI: 10.2196/72893

Can digital tools improve clinical care in psychiatry? (odnośnik otworzy się w nowym oknie)

Autorzy: Myin-Germeys, I.
Opublikowane w: DUSUNEN ADAM-JOURNAL OF PSYCHIATRY AND NEUROLOGICAL SCIENCES, Numer 36, 2023, Strona(/y) 1-3, ISSN 1018-8681
Wydawca: Bakirkoy Research and Training Hospital for Psychiatry, Neurology and Neurosurgery
DOI: 10.14744/dajpns.2022.00200

mHealth in psychiatry: A pathway to person-centered care (odnośnik otworzy się w nowym oknie)

Autorzy: Myin-Germeys, I.
Opublikowane w: Psychiatry Research, Numer 319, 2023, Strona(/y) 114978, ISSN 0165-1781
Wydawca: Elsevier BV
DOI: 10.1016/j.psychres.2022.114978

Metóda zachytávania každodenných zážitkov v naturalistických podmienkach: Nomotetický a idiografický prístup. (odnośnik otworzy się w nowym oknie)

Autorzy: Dančík, D., Hajdúk, M., Heretik, A.
Opublikowane w: E-Psychologie, 2022, ISSN 1802-8853
Wydawca: Czech-Moravian Psychological Society
DOI: 10.29364/epsy.448

Weaving EU digital health policy into national healthcare practices. The making of a reimbursement standard for digital health technologies in Belgium (odnośnik otworzy się w nowym oknie)

Autorzy: Lievevrouw, E., Marelli, L. & Van Hoyweghen, I.
Opublikowane w: Social Science & Medicine, Numer 346, 2024, Strona(/y) 116620, ISSN 0277-9536
Wydawca: Pergamon Press Ltd.
DOI: 10.1016/j.socscimed.2024.116620

From progress to paralysis: bridging the translation gap in digital mental health care? (odnośnik otworzy się w nowym oknie)

Autorzy: Inez Myin-Germeys, Elisa Lievevrouw, Simona di Folco, Ine Van Hoyweghen, Luca Marelli, Michal Hajdúk, Georgia Koppe, Ulrich Reininghaus, Anita Schick, Iveta Nagyova, Jeroen Weermijer, Matthias Schwannauer
Opublikowane w: Psychological Medicine, Numer 55, 2025, ISSN 0033-2917
Wydawca: Cambridge University Press
DOI: 10.1017/s0033291725102614

Implementácia digitálnych technológií v neuropsychologickej praxi v telemedicíne

Autorzy: Brandoburová, P., & Dančík, D.
Opublikowane w: In P. Kulišťák (Ed.), 2023
Wydawca: Klinická neuropsychologie v praxi

Multimodal teacher forcing for reconstructing nonlinear dynamical systems (odnośnik otworzy się w nowym oknie)

Autorzy: Brenner, M., Koppe, G., & Durstewitz, D.
Opublikowane w: 2022, ISSN 2331-8422
Wydawca: Cornell University
DOI: 10.48550/arxiv.2212.07892

A control theoretic approach to evaluate and inform ecological momentary interventions. (odnośnik otworzy się w nowym oknie)

Autorzy: Fechtelpeter, J., Rauschenberg, C., Jamalabadi, H., Boecking, B., van Amelsvoort, T., Reininghaus, U., Durstewitz, D., & Koppe, G.
Opublikowane w: 2023
Wydawca: PsyArXiv
DOI: 10.31234/osf.io/97teh

Understanding appropriation of digital self-monitoring tools in mental health care – an implementation pilot (odnośnik otworzy się w nowym oknie)

Autorzy: de Thurah L, Kiekens G, Weermeijer J, Uyttebroek L, Wampers M, Bonnier RAM, Myin-Germeys I
Opublikowane w: 2024
Wydawca: OSF Preprint
DOI: 10.31219/osf.io/fm8kt

Digital twins of human social interactions reveal behavioral strategies in exchange games (odnośnik otworzy się w nowym oknie)

Autorzy: Manuel Brenner, Ismail Guennouni, Daniel Durstewitz, Stephanie Nicole Lyn Schmidt, Stefanie Lis, Peter Kirsch, Georgia Koppe
Opublikowane w: 2025
Wydawca: Center for Open Science
DOI: 10.31234/osf.io/m6pnq

Computational network models for forecasting and control of mental health trajectories in digital applications (odnośnik otworzy się w nowym oknie)

Autorzy: Janik Fechtelpeter, Christian Rauschenberg, Christian Goetzl, Selina Hiller, Eva Wierzba, Niklas Emonds, Silvia Krumm, Ulrich Reininghaus, Daniel Durstewitz, Georgia Koppe
Opublikowane w: npj Digital Medicine, Numer 9, 2026, ISSN 2398-6352
Wydawca: Springer Science and Business Media LLC
DOI: 10.1038/s41746-025-02252-3

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