Actionable eUropean ROadmap for early-life health Risk Assessment of micro- and nanoplastics

Información del proyecto

AURORA

Identificador del acuerdo de subvención: 964827

DOI

10.3030/964827

Fecha de la firma de la CE 2 Febrero 2021

Fecha de inicio 1 Abril 2021

Fecha de finalización 30 Septiembre 2026

Financiado con arreglo a

• SOCIETAL CHALLENGES - Health, demographic change and well-being

Coste total

€ 5 996 315,00

Aportación de la UE

€ 5 996 315,00

Coordinado por

UNIVERSITAIR MEDISCH CENTRUM UTRECHT
Netherlands

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Resultado final

Documents, reports (3)

HRMS profiling of placenta or cord blood metabolome

Report describing the results of the HRMS analyses on biological samples from the BISC and Environage cohort.

Cluster brochure

Leaflet describing the cluster activities and participating projects

Protocols of high-throughput analysis of MNPs

A description of the key requirements to scale analytical methods for population screening including: 1) benchmark quantification methods for MNPs using untargeted Pyr-HRMS against traditional targeted approaches ; 2) identification of best practices for standard selection, eliminating background contamination and reagent purity; 3) evaluation of the effect of sample preparation on MNP chemistry.

Demonstrators, pilots, prototypes (1)

Sample pre-processing workflow and standard operating procedures for measuring MNPs in complex human sample matrices

A report describing workflows and SOPs using the optimized methods – describing the effects of sample treatments on 1) formation of secondary NPs and 2) effects of these treatments on NP, which may react differently than the larger MNPs.

Websites, patent fillings, videos etc. (1)

Database of spectroscopic and morphological fingerprints of aged MNPs

Database on the chemical and morphological changes occurring during NP formation, as well as on the surface of the parent plastic. This will provide a key deliverable supporting MNP risk assessment through developing a database of signatures for in-depth characterization of MNPs.

Publicaciones

Other (4)

Experimental human placental models for studying uptake, transport and toxicity of micro- and nanoplastics

Autores: Hanna M. Dusza a 1, Jeske van Boxel b 1, Majorie B.M. van Duursen b, Markus M. Forsberg c, Juliette Legler a, Kirsi H. Vähäkangas c
Publicado en: Elsevier ScienceDirect, Edición volume 860, 20 february 2023, 2023, Página(s) 160403
Editor: Elsevier, Science direct

Progress Towards an Accurate Detection, Characterization, and Exposure Assessment of Micro and Nanoplastics to Support Risk Assessments for Early Life Health Within the AURORA Project

Autores: Mandemaker, Laurens D. B.; Dusza, Hanna; Meirer, Florian; van Boxel, Jesker; van Duursen, Majorie; Forsberg, Markus; Legler, Juliette; Vähäkangas, Kirsi; Zimmermann, Lisa
Publicado en: online: https://zenodo.org/records/7968133 - online brochure/poster, Edición May 25, 2023 - v1, 2023
Editor: zenodo.org & AURORA/CUSP
DOI: 10.5281/zenodo.7968132

Spectro‐Microscopic Techniques for Studying Nanoplastics in the Environment and in Organisms

Autores: Laurens D. B. Mandemaker; Florian Meirer
Publicado en: Angewandte Chemie - International Edition, Edición October 24, 2022, 2022
Editor: Wiley-Blackwell
DOI: 10.1002/anie.202210494

CUSP Brochure

Autores: CUSP
Publicado en: ZENODO, Edición January 12, 2022, 2022
Editor: CUSP: www.cusp-research.eu
DOI: 10.5281/zenodo.5837595

Conference proceedings (1)

Sample Pre-processing Protocols for the (Spectro-)Microscopic Analysis of Micro- & Nanoplastics (MNPs) in Maternal and Fetal Tissues

Autores: Zoutendijk, Laura M.; Mandemaker, Laurens D. B.; Matla, Zenzi; Zimmermann, Lisa; van Dalen, Lonneke; Weckhuysen, Bert M.; Meirer, Florian
Publicado en: Edición 1, 2023
Editor: Zenodo
DOI: 10.5281/zenodo.7967295