CORDIS - Forschungsergebnisse der EU
CORDIS

Plastics fate and effects in the human body

Leistungen

Review of current regulations, and policy and market

This will identify any knowledge gaps that need to be addressed through project activities as well as understanding the current state of the art including products on the market and identifying key stakeholders

Report on selected MP/NP and basic PChem features

In the report it will be explained how the selection storage distribution and basic characterization of material is performed In addition some techniques for labeling and traceability of materials will be described

Overview of human exposure sources and levels of MP/NP

Report with a comprehensive overview of the human exposure levels of MPNP related to their different sources based on the recent literature and measured and modelled data from previous projects

Cluster brochure

The cluster brochure will be developed

Establishing a human health RA strategy for MP/NP

This will be implemented in the form of an integrated testing strategy (ITS) which specifies a tied, step-by-step procedure with the associated test systems (IATAs). Interim report by M24.

State of the art in microplastic risk assessement

The report will summarise the legal requirements for the regulation of plastic Possible gaps in the current legal frameworks as well as data needs will be identified and specified

Prototype of the prospective multi criteria decision support system (PMCDS)

The PMCSD will support end-users through an early decision-making process in an prospective approach integrating data on applications, performance needs, exposure and hazard. This prototype will allow the conduction of case studies.

Joint policy briefs 1
Risk assessment of MP/NP to act as pathogen vectors

Report with the results obtained through flow cytometry-based method and molecular tools.

Modelling of MP/NP for environmental fate, human exposure and toxicokinetics

The mathematical equations that compose the environmental fate, human exposure, and toxicokinectic prediction models as well as the parameters considered will be collected and explained in a report.

Web and social media presence

A project website will be produced that acts as a repository and shop front for all publishable project output This will connect with social media channels such as LinkedIn Twitter and YouTube Task 61

Prototype of a web-based decision support system

A web-based e-tool will be developed to estimate human and environmental health risks along the lifecycle of plastic materials and products. The prototype will include most of the features and presented for discussion to the partners.

Cluster web portal and visual identity

The cluster web portal and visual identity will be developed.

Veröffentlichungen

Digestión gastrointestinal y fermentación colónica de microplásticos biodegradables de ácido poliláctico (PLA) y su interacción con la microbiota intestinal

Autoren: Jiménez Arroyo, Cristina; Tamargo García, Alba; Molinero, Natalia; Jiménez Reinosa, Julián; Alcolea-Rodríguez, Víctor; Portela, Raquel; Bañares, Miguel A.; Fernández Lozano, José Francisco; Moreno-Arribas, M. Victoria
Veröffentlicht in: instname:Consejo Superior de Investigaciones Científicas (CSIC), Ausgabe 1, 2023
Herausgeber: DIGITAL CSIC

Useful Gut Model for Plastic Particles Assessing

Autoren: Giulia, Antonello; Esposito, Marianna; Barbero, Francesco; Macaraig Mansilungan, Camille; Fenoglio, Ivana; Riganti, Chiara; Bergamaschi, Enrico
Veröffentlicht in: CUSP Meeting, 2022
Herausgeber: CUSP
DOI: 10.5281/zenodo.7267318

Co-culture of human type I and type II pneumocyte cell lines as a model of alveolar epithelium

Autoren: Boland, Sonja; Brookes, Oliver; Kuen, Rene Lai; Miremont, Dorian; Eon-Bertho; Mawas, Safaa; Baeza-Squiban, Amelle
Veröffentlicht in: STCM 2022, 2022
Herausgeber: STCM 2022
DOI: 10.5281/zenodo.7142483

Microplásticos y microbiota. Impacto de la ingesta de diferentes tipos de microplásticos sobre la microbiota colónica humana

Autoren: Tamargo García, Alba; Molinero, Natalia; Jiménez Arroyo, Cristina; Jiménez Reinosa, Julián; Alcolea-Rodriguez, Victor; Portela, Raquel; Bañares, Miguel A.; Fernández, Jose F.; Moreno-Arribas, M. Victoria
Veröffentlicht in: instname:, Ausgabe 1, 2022
Herausgeber: CSIC

From principles to reality. FAIR implementation in the nanosafety community

Autoren: Dumit, Verónica I.; Ammar, Ammar; Bakker, Martine; Bañares, Miguel A.; Bossa, Cecilia; Costa, Anna; Cowie, Hilary; Drobne, Damjana; Exner, Thomas E.; Farcal, Lucian; Friedrichs, Steffi; Furxhi, Irini; Grafström, Roland; Haase, Andrea; Himly, Martin; Jeliazkova, Nina; Lynch, Iseult; Maier, Dieter; Noorlander, Cornelle W.; Shin, Hyun Kil; Soler-Illia, Galo J.A.A.; Suarez-Merino, Blanca; Willighag
Veröffentlicht in: Nano Today, Ausgabe 3, 2023, ISSN 1748-0132
Herausgeber: Elsevier BV
DOI: 10.1016/j.nantod.2023.101923

Nano- and microplastics commonly cause adverse impacts on plants at environmentally relevant levels: A systematic review

Autoren: Zantis, L.J.; Borchi, C.; Vijver, M.G.; Peijnenburg, W.J.G.M.; Di Lonardo, S.; Bosker, T.
Veröffentlicht in: Science of the total environment 867 (2023). doi:10.1016/j.scitotenv.2022.161211, Ausgabe 3, 2023, ISSN 0048-9697
Herausgeber: Elsevier BV
DOI: 10.1016/j.scitotenv.2022.161211

The analytical quest for sub-micron plastics in biological matrices

Autoren: Fazel Abdolahpur Monikh; Fazel Abdolahpur Monikh; Martina G. Vijver; Denise M. Mitrano; Heather A. Leslie; Zhiling Guo; Peng Zhang; Iseult Lynch; Eugenia Valsami-Jones; Willie J.G.M. Peijnenburg
Veröffentlicht in: Nano Today, 41, Ausgabe 3, 2021, ISSN 1748-0132
Herausgeber: Elsevier BV
DOI: 10.1016/j.nantod.2021.101296

perspectives on toxicokinetics of nanoscale plastic debris in organisms

Autoren: Fazel Abdolahpur Monikh; Martina G. Vijver; Raine Kortet; Iseult Lynch; Willie J. G. M. Peijnenburg
Veröffentlicht in: Environmental Science: Nano, Ausgabe 3, 2022, ISSN 2051-8161
Herausgeber: RSC
DOI: 10.1039/d1en00425e

Submicron Plastic Adsorption by Peat, Accumulation in Sphagnum Mosses and Influence on Bacterial Communities in Peatland Ecosystems

Autoren: Mandar Bandekar; Fazel Abdolahpur Monikh; Jukka Kekäläinen; Teemu Tahvanainen; Raine Kortet; Peng Zhang; Zhiling Guo; Jarkko Akkanen; Jari T. T. Leskinen; Miguel A. Gomez-Gonzalez; Gopala Krishna Darbha; Hans-Peter Grossart; Eugenia Valsami-Jones; Jussi V. K. Kukkonen
Veröffentlicht in: Environmental Science and Technology, Ausgabe 3, 2022, Seite(n) 15661–15671, ISSN 0013-936X
Herausgeber: American Chemical Society
DOI: 10.1021/acs.est.2c04892

From properties to toxicity: Comparing microplastics to other airborne microparticles

Autoren: Simon Wieland, Aylin Balmes, Julian Bender, Jonas Kitzinger, Felix Meyer, Anja FRM Ramsperger, Franz Roeder, Caroline Tengelmann, Benedikt H. Wimmer, Christian Laforsch, Holger Kress
Veröffentlicht in: Journal of Hazardous Materials, Ausgabe Volume 428,, 2022, ISSN 0304-3894
Herausgeber: Elsevier BV
DOI: 10.1016/j.jhazmat.2021.128151

Biomarkers of oxidative stress, inflammation, and genotoxicity to assess exposure to micro- and nanoplastics. A literature review

Autoren: Panizzolo, Marco; Martins, Vitor Hugo; Ghelli, Federica; Squillacioti, Giulia; Bellisario, Valeria; Garzaro, Giacomo; Bosio, Davide; Colombi, Nicoletta; Bono, Roberto; Bergamaschi, Enrico
Veröffentlicht in: Ecotoxicology and Environmental Safety Volume 267, 15 November 2023, 115645, Ausgabe Volume 267, 15 November 2023, 115645, 2023, ISSN 1090-2414
Herausgeber: Elsevier
DOI: 10.1016/j.ecoenv.2023.115645

The gut microbiota, a key to understanding the health implications of micro(nano)plastics and their biodegradation

Autoren: Cristina Jiménez‐Arroyo; Alba Tamargo; Natalia Molinero; M. Victoria Moreno‐Arribas
Veröffentlicht in: Microbial Biotechnology, Vol 16, Iss 1, Pp 34-53 (2023), Ausgabe 2, 2022, ISSN 1751-7915
Herausgeber: Microbial Biotechnology
DOI: 10.1111/1751-7915.14182

Estrogenic activity of plastic nanoparticle mixtures under <i>in vitro</i> settings

Autoren: Lucija Božičević; Korinna Altmann; Jana Hildebrandt; Xenia Knigge; Valerije Vrček; Nikolina Peranić; Nikolina Kalčec; Ivana Vinković Vrček
Veröffentlicht in: Environmental Science: Nano, Ausgabe 2, 2024, Seite(n) Ausgabe 5, 2024, ISSN 2051-8161
Herausgeber: RSC
DOI: 10.1039/d3en00883e

Exposure protocol for ecotoxicity testing of microplastics and nanoplastics

Autoren: Fazel Abdolahpur Monikh; Anders Baun; Nanna B. Hartmann; Raine Kortet; Jarkko Akkanen; Jae-Seong Lee; Huahong Shi; Elma Lahive; Emilia Uurasjärvi; Nathalie Tufenkji; Korinna Altmann; Yosri Wiesner; Hans-Peter Grossart; Willie Peijnenburg; Jussi V. K. Kukkonen
Veröffentlicht in: NATURE PROTOCOLS, Ausgabe 3, 2023, Seite(n) 3534–3564, ISSN 1750-2799
Herausgeber: NATURE.COM
DOI: 10.1038/s41596-023-00886-9

Sub-micro- and nano-sized polyethylene terephthalate deconstruction with engineered protein nanopores

Autoren: Robles-Martín, Ana; Amigot-Sánchez, Rafael; Fernandez-Lopez, Laura; Gonzalez-Alfonso, Jose L; Roda, Sergi; Alcolea-Rodriguez, Víctor; Heras-Márquez, Diego; Almendral, David; Coscolín, Cristina; Plou, Francisco J; Portela, Raquel; Bañares, Miguel A; Martínez-del-Pozo, Álvaro; García-Linares, Sara; Ferrer, Manuel; Guallar, Víctor
Veröffentlicht in: Nature Catalysis, Ausgabe 3, 2023, Seite(n) 1174–1185, ISSN 2520-1158
Herausgeber: Nature Catalysis
DOI: 10.1038/s41929-023-01048-6

Nano- and microplastics: a comprehensive review on their exposure routes, translocation, and fate in humans

Autoren: Ramsperger, Anja FRM; Bergamaschi, Enrico; Panizzolo, Marco; Fenoglio, Ivana; Barbero, Francesco; Peters, Ruud; Undas, Anna; Purker, Sebastian; Giese, Bernd; Lalyer, Carina R; Tamargo, Alba; Moreno-Arribas, M Victoria; Grossart, Hans-Peter; Kühnel, Dana; Dietrich, Jana; Paulsen, Friedrich; Afanou, Anani K; Zienolddiny-Narui, Shan; Eriksen Hammer, Stine; Kringlen Ervik, Torunn; Graff, Pål; Brinch
Veröffentlicht in: NanoImpact, Ausgabe 2, 2022, ISSN 2452-0748
Herausgeber: Elsevier B.V.
DOI: 10.1016/j.impact.2022.100441

Quantifying the trophic transfer of sub-micron plastics in an assembled food chain

Autoren: Monikh, Fazel Abdolahpur; Holm, Sille; Kortet, Raine; Bandekar, Mandar; Kekäläinen, Jukka; Koistinen, Arto; Leskinen, Jari TT; Akkanen, Jarkko; Huuskonen, Hannu; Valtonen, Anu; Dupuis, Lan; Peijnenburg, Willie; Lynch, Iseult; Valsami-Jones, Eugenia; Kukkonen, Jussi V.K.
Veröffentlicht in: Nano Today, Ausgabe 3, 2022, ISSN 1878-044X
Herausgeber: Elsevier
DOI: 10.1016/j.nantod.2022.101611

Simulated Gastrointestinal Digestion of Polylactic Acid (Pla) Biodegradable Microplastics and Their Interaction with Gut Microbiota

Autoren: Jiménez Arroyo, Cristina; Tamargo, Alba; Molinero, Natalia; Reinosa, J. J.; Alcolea-Rodríguez, Víctor; Portela, Raquel; Bañares, Miguel A.; Fernández Lozano, José Francisco; Moreno-Arribas, M. Victoria
Veröffentlicht in: Crossref, Ausgabe 1, 2023, Seite(n) 166003, ISSN 0048-9697
Herausgeber: Elsevier BV
DOI: 10.2139/ssrn.4463181

Role of the Protein Corona in the Colloidal Behavior of Microplastics

Autoren: Marion Schvartz; Florent Saudrais; Stéphanie Devineau; Stéphane Chédin; Frédéric Jamme; Jocelyne Leroy; Karol Rakotozandriny; Olivier Taché; Guillaume Brotons; Serge Pin; Yves Boulard; Jean-Philippe Renault
Veröffentlicht in: "Langmuir, 2023, 39 (12), pp.4291-4303. &#x27E8;10.1021/acs.langmuir.2c03237&#x27E9;", Ausgabe 3, 2023, Seite(n) 4291–4303, ISSN 1520-5827
Herausgeber: American Chemical Society
DOI: 10.1021/acs.langmuir.2c03237

Defining Quality Criteria for Nanoplastic Hazard Evaluation: The Case of Polystyrene Nanoplastics and Aquatic Invertebrate Daphnia spp.

Autoren: Jemec Kokalj, Anita; Heinlaan, Margit; Novak, Sara; Drobne, Damjana; Kühnel, Dana
Veröffentlicht in: Volume 13, Ausgabe 3, 2023, ISSN 2079-4991
Herausgeber: MDPI
DOI: 10.3390/nano13030536

Nominally identical microplastic models differ greatly in their particle-cell interactions

Autoren: Simon Wieland; Anja F. R. M. Ramsperger; Wolfgang Gross; Moritz Lehmann; Thomas Witzmann; Anja Caspari; Martin Obst; Stephan Gekle; Günter K. Auernhammer; Andreas Fery; Christian Laforsch; Holger Kress
Veröffentlicht in: Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024), Ausgabe 1, 2024, Seite(n) 15:922, ISSN 2041-1723
Herausgeber: Nature Publishing Group
DOI: 10.1038/s41467-024-45281-4

Evaluation of Nanoparticle Tracking Analysis (NTA) for the Measurement of Nanoplastics in Drinking Water

Autoren: Ruud J.B. Peters; Emma Relou; Eelco L.E. Sijtsma; Anna K. Undas
Veröffentlicht in: Research Square, Ausgabe 1, 2024, ISSN 2693-5015
Herausgeber: Research Square
DOI: 10.21203/rs.3.rs-1809144/v1

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