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CORDIS - Wyniki badań wspieranych przez UE
CORDIS

Multidisciplinary Expert System for the Assessment & Management of Complex Brain Disorders

CORDIS oferuje możliwość skorzystania z odnośników do publicznie dostępnych publikacji i rezultatów projektów realizowanych w ramach programów ramowych HORYZONT.

Odnośniki do rezultatów i publikacji związanych z poszczególnymi projektami 7PR, a także odnośniki do niektórych konkretnych kategorii wyników, takich jak zbiory danych i oprogramowanie, są dynamicznie pobierane z systemu OpenAIRE .

Rezultaty

Scientific Aims and Testable Hypotheses- v1 (odnośnik otworzy się w nowym oknie)

This deliverable will firstly contain the agreed upon scientific aims and hypotheses tested through specific proposed analyses during the project

Participant recruitment, Pre-existing RWD access, Prospective RWD acquisition and secure storage -v3 (odnośnik otworzy się w nowym oknie)

D8.3-D8.7, reported in 5 deliverables, each one being an update of the previous one, aim to: (a) reflect the number of participants enrolled prospectively on a biannual basis until the end of the study and verify ethical RWD acquisition following informed consent and IRB approval; (b) document the amount of RWD reflective of our CoBraD Protocol, acquired from pre-existing databases on a biannual basis within the study; (c) reflect the actual RWD acquired and stored on a biannual basis in our shared and secure database in an anonymised manner. D8.5 & D8.7 will also document the pilots’ operation and execution and also evaluate the platform from the users’ perspective. They will also present lessons learnt during the project, constituting methodological adoption guidelines for the utilisation of the platform.

Participant recruitment, Pre-existing RWD access, Prospective RWD acquisition and secure storage -v2 (odnośnik otworzy się w nowym oknie)

D83D87 reported in 5 deliverables each one being an update of the previous one aim to a reflect the number of participants enrolled prospectively on a biannual basis until the end of the study and verify ethical RWD acquisition following informed consent and IRB approval b document the amount of RWD reflective of our CoBraD Protocol acquired from preexisting databases on a biannual basis within the study c reflect the actual RWD acquired and stored on a biannual basis in our shared and secure database in an anonymised manner D85 D87 will also document the pilots operation and execution and also evaluate the platform from the users perspective They will also present lessons learnt during the project constituting methodological adoption guidelines for the utilisation of the platform

Business and Exploitation Plan - v1 (odnośnik otworzy się w nowym oknie)

This deliverable will deal with an early version of the Business and Exploitation Plan

Communication & Dissemination Plan (odnośnik otworzy się w nowym oknie)

This deliverable will deal with the MESCoBrad Communication Dissemination Plan with a view to increase the impact of MESCoBrad ensuring the widest possible visibility of the project promoting its activities and maximising its potential outreach

Sex and Gender Impact Assessment report (odnośnik otworzy się w nowym oknie)

This report will assess the social research outcomes on gender positive and negative impact

System requirements & architecture (odnośnik otworzy się w nowym oknie)

Based on the scenarios setup in WP3 this deliverable will present the functional and nonfunctional system requirements and the overall solution architecture that will be the baseline for the development WPs The architecture will describe in detail the integration logic and interfaces between the involved tools and services produced by WP5 and WP6 as well as the interaction of the components

The CoBraD ethical and regulatory framework v2 (odnośnik otworzy się w nowym oknie)

Update of v1 of this deliverable report.

The CoBraD ethical and regulatory framework (odnośnik otworzy się w nowym oknie)

Identification of the applicable legal and ethical regulations applicable to the CoBraD project Special attention will be given to EU law on personal data protection the GDPR and any other applicable regulations or guidance at EU and MS level applicable ethical standards in EU research projects within the CoBraD subjectmatter and and other relevant rules and regulations The following shall constitute particular points of attention 1 Any special derogations pertaining to the rights of data subjects or the processing of genetic biometric andor health data have been established under the national legislation of the EU country where the research takes place 2 Justification for the processing of sensitive personal data 3 The data minimization principle 4 International data transfers and confirmation that such transfers are in accordance with Chapter V of the General Data Protection Regulation 2016679 5 In the event of personal data transferred from a nonEU country to the EU or another third state confirmation that such transfers comply with the laws of the country in which the data was collected

Participant recruitment, Pre-existing RWD access, Prospective RWD acquisition and secure storage -v4 (odnośnik otworzy się w nowym oknie)

D8.3-D8.7, reported in 5 deliverables, each one being an update of the previous one, aim to: (a) reflect the number of participants enrolled prospectively on a biannual basis until the end of the study and verify ethical RWD acquisition following informed consent and IRB approval; (b) document the amount of RWD reflective of our CoBraD Protocol, acquired from pre-existing databases on a biannual basis within the study; (c) reflect the actual RWD acquired and stored on a biannual basis in our shared and secure database in an anonymised manner. D8.5 & D8.7 will also document the pilots’ operation and execution and also evaluate the platform from the users’ perspective. They will also present lessons learnt during the project, constituting methodological adoption guidelines for the utilisation of the platform.

MES-CoBraD Validation Framework (odnośnik otworzy się w nowym oknie)

This deliverable is related to the documentation of the evaluation framework and validation methodology defining the various practices for obtaining feedback from endusers and including a set of testcases to be executed by the endusers

The ETHAI model (odnośnik otworzy się w nowym oknie)

This report will define a set of principles for health research making use of AI technology in CoBraD assessment and management

Report on the communication and dissemination activities implemented & final exploitation plan (odnośnik otworzy się w nowym oknie)

This deliverable will include the results of the communication, dissemination and exploitation activities.

Scientific Aims, Testable Hypotheses and Scientifically Sound, Evidence-based Recommendations for the Assessment and Management of CoBraD in real-world practice - v4 (odnośnik otworzy się w nowym oknie)

D4.3-D4.6 will contain the updates of D4.2 in the following months of project duration. Furthermore, it will include all submitted scientific publications, resulting in scientifically sound, evidence-based recommendations informing professional organisations, policy, healthcare, and insurance stakeholders on changes that can improve assessment and management of CoBraD in real-world practice. D4.6 will be the final outcome of WP4 providing the summary of all scientific publications that resulted in the project, concluding based on them to the final Guidelines for the Professional Diagnostic Practice or Safety and Efficacy of Real-World Medical Therapies.

Assessment of the CoBraD PUCs against ethical and legal standards (odnośnik otworzy się w nowym oknie)

This report will release a first assessment about the compliance of CoBrad Pilot Use Cases PUC with the essential regulatory ethical and legal framework identified under T21 Precisely the document will report a how the consortium ensures respect for research or study participants and for human dignity and fair distribution of the benefits and burden of research and how consortium will protect the values rights and interests of the research participants particularly with reference to vulnerable groups children disable people b how the consortium ensures GDPR compliance concerning to research which involves processing of personal data regardless of the method used eg interviews questionnaires direct online retrieval etc c whether the PUCs have obtained the necessary opinionsapprovals by local and national ethics committees andor competent authorities for the research with humans performed in the pilot studies first study subject approvals package

MES-CoBraD Advanced Analytics Evaluation (odnośnik otworzy się w nowym oknie)

This will serve as a comprehensive assessment of the final release of the Advanced Analytics modules and features, benchmarked against the user requirements for executing the project's use cases. This evaluation aims to quantify the system's efficacy and accuracy in relation to predetermined criteria, thereby informing any requisite refinements or future iterations.

Final publishable report (odnośnik otworzy się w nowym oknie)

This will summarise the project’s objectives, activities and achievements.

Final Assessment of the CoBraD PUCs against ethical and legal standards (odnośnik otworzy się w nowym oknie)

Final report on the assessment of the ethics and legal compliance of PUCs

Communication, Dissemination & Exploitation Activities Report and Plan (odnośnik otworzy się w nowym oknie)

This deliverable will i) report on the Dissemination and exploitation activities carried out within the First Reporting Period, and ii) based on the first period target analysis, will focus on a revised Communication, Dissemination and Exploitation Plan for the Second half of the project

Establishment of the External Advisory Board (odnośnik otworzy się w nowym oknie)

This deliverable will document the selection procedure and the presentation of an External Advisory Board which will serve to provide an unbiased and ongoing perspective on the developed protocols and their implementation ensuring the project reaches its goals The board will cover all the medical technological community and ethical aspects and it will be consisted by members with professional expertise in these subjects

Report on the registration of the Studies (odnośnik otworzy się w nowym oknie)

This deliverable is related to the registration of the study on the European Union Clinical Trials Register EUCTR administered by the European Medicines Agency EMA We will register the multicenter prospective cohort study with the inclusion and exclusion criteria as well as the primary objectives and methodology of the study

Project Manual - CoBraD RWD, Updated MES-CoBraD Protocols and Quality and Quantity (Q&Q) Evaluation - v1 (odnośnik otworzy się w nowym oknie)

This deliverable will Provide the updated specific characteristics of the populations tobestudied and the specific data from these populations tobeacquired The purpose is to have an agreement between research participating organisations and community stakeholders on the utility and acceptability of RWD to be used in future analyses by respecting medical ethics values autonomy beneficence nonmaleficence justice and containing the approvals of Pilot organisations IRBsdefine the final updated protocols to be pursued as part of data acquisition sharing and information dissemination after receiving input from stakeholders and oversight by the External Advisory Board The purpose is to have an agreed upon protocol on the acquisition and handling of RWD that will be the basis for the threeyear research and innovation plandefine the critical elements all data should have to be considered of high acceptable quality as well as the amount of data necessary to achieve the overall project objectives

Project Manual - CoBraD RWD, Updated MES-CoBraD Protocols and Quality and Quantity (Q&Q) Evaluation - v2 (odnośnik otworzy się w nowym oknie)

This deliverable will be an update of D31 as well as provide the highlevel methodology of the project that will guide the rest of the projects activities based on usage scenarios as defined with the support of the pilot organisations

Report on the posting of project results (odnośnik otworzy się w nowym oknie)

This deliverable is related to the disclosure of the results to the EMA within 12 months of trial completion, including salient features such as results and statistical analyses, participants’ baseline characteristics, and protocol deviations, as well as discussion of design limitations and caveats.

Scientifically Sound, Evidence-based Recommendations for the Assessment and Management of CoBraD in real-world practice - final (odnośnik otworzy się w nowym oknie)

D4.3-D4.6 will contain the updates of D4.2 in the following months of project duration. Furthermore, it will include all submitted scientific publications, resulting in scientifically sound, evidence-based recommendations informing professional organisations, policy, healthcare, and insurance stakeholders on changes that can improve assessment and management of CoBraD in real-world practice. D4.6 will be the final outcome of WP4 providing the summary of all scientific publications that resulted in the project, concluding based on them to the final Guidelines for the Professional Diagnostic Practice or Safety and Efficacy of Real-World Medical Therapies.

Final report on opportunity-based promotional activities (odnośnik otworzy się w nowym oknie)

This deliverable will report all opportunity-based promotional activities delivered throughout the duration of the project. Examples of such activities can be promotion of the project to specific stakeholder groups in third party events, co-organisation of promotional activities with relevant projects/initiatives/communities, etc.

Scientific Aims, Testable Hypotheses and Scientifically Sound, Evidence-based Recommendations for the Assessment and Management of CoBraD in real-world practice - v2 (odnośnik otworzy się w nowym oknie)

D43D46 will contain the updates of D42 in the following months of project duration Furthermore it will include all submitted scientific publications resulting in scientifically sound evidencebased recommendations informing professional organisations policy healthcare and insurance stakeholders on changes that can improve assessment and management of CoBraD in realworld practice D46 will be the final outcome of WP4 providing the summary of all scientific publications that resulted in the project concluding based on them to the final Guidelines for the Professional Diagnostic Practice or Safety and Efficacy of RealWorld Medical Therapies

Scientific Aims, Testable Hypotheses and Scientifically Sound, Evidence-based Recommendations for the Assessment and Management of CoBraD in real-world practice - v3 (odnośnik otworzy się w nowym oknie)

D4.3-D4.6 will contain the updates of D4.2 in the following months of project duration. Furthermore, it will include all submitted scientific publications, resulting in scientifically sound, evidence-based recommendations informing professional organisations, policy, healthcare, and insurance stakeholders on changes that can improve assessment and management of CoBraD in real-world practice. D4.6 will be the final outcome of WP4 providing the summary of all scientific publications that resulted in the project, concluding based on them to the final Guidelines for the Professional Diagnostic Practice or Safety and Efficacy of Real-World Medical Therapies.

Stakeholder engagement strategy (odnośnik otworzy się w nowym oknie)

This deliverable represents a comprehensive sound KPIdriven strategy that the project will follow throught its duration in order to identify and engage with relevant stakeholders The strategy will be used as a roadmap of engagement activities per stakeholder category and at multistakeholder level and will be revisited throughout the project

Participant recruitment, Pre-existing RWD access, Prospective RWD acquisition and secure storage -v1 (odnośnik otworzy się w nowym oknie)

D83D87 reported in 5 deliverables each one being an update of the previous one aim to a reflect the number of participants enrolled prospectively on a biannual basis until the end of the study and verify ethical RWD acquisition following informed consent and IRB approval b document the amount of RWD reflective of our CoBraD Protocol acquired from preexisting databases on a biannual basis within the study c reflect the actual RWD acquired and stored on a biannual basis in our shared and secure database in an anonymised manner D85 D87 will also document the pilots operation and execution and also evaluate the platform from the users perspective They will also present lessons learnt during the project constituting methodological adoption guidelines for the utilisation of the platform

Participant recruitment, Pre-existing RWD access, Prospective RWD acquisition and secure storage & Pilots Evaluation and Impact Assessment -final (odnośnik otworzy się w nowym oknie)

D8.3-D8.7, reported in 5 deliverables, each one being an update of the previous one, aim to: (a) reflect the number of participants enrolled prospectively on a biannual basis until the end of the study and verify ethical RWD acquisition following informed consent and IRB approval; (b) document the amount of RWD reflective of our CoBraD Protocol, acquired from pre-existing databases on a biannual basis within the study; (c) reflect the actual RWD acquired and stored on a biannual basis in our shared and secure database in an anonymised manner. D8.5 & D8.7 will also document the pilots’ operation and execution and also evaluate the platform from the users’ perspective. They will also present lessons learnt during the project, constituting methodological adoption guidelines for the utilisation of the platform.

Stakeholder engagement final report (odnośnik otworzy się w nowym oknie)

This deliverable provides information on all the engagement activities that took place throughout the duration of the project according to the stakeholder engagement strategic goals and KPIs, also depicting main outcomes and lessons learned.

MES-CoBraD Advanced Analytics Analytics Release 2.00 (odnośnik otworzy się w nowym oknie)

This will be an updated and final version of the D6.1 with all the analysis as well as the reports of the system.

MES-CoBraD Advanced Analytics Release 1.00 (odnośnik otworzy się w nowym oknie)

This will be a production ready and first release of the algorithm expert system, including all the optimizations and additional functionalities from the main prototype.

Data integration, harmonisation, sharing and security - v1 (odnośnik otworzy się w nowym oknie)

In this deliverable the integration and harmonisation process from heterogeneous data sources will be widely analysed and the adopted solutions and standards will be presented in detail. Moreover, the security aspect, its relative criticality and the adopted countermeasures will be discussed. Finally, the improvement provided to the MES CoBraD project by the introduction of sharing capabilities and the availability of a front-end for the management of data will be presented.

Data integration, harmonisation, sharing and security - final (odnośnik otworzy się w nowym oknie)

This deliverable will be updated and be the final version of D5.1.

Website (odnośnik otworzy się w nowym oknie)

This deliverable will consists of the MESCoBrad project web site graphical and textual design and implementation

Promotional and informational material (odnośnik otworzy się w nowym oknie)

This deliverable will deal with the graphical and textual design of promotional and informational material

Online materials (odnośnik otworzy się w nowym oknie)

This deliverable will deal with the online material

Publikacje

Medial temporal lobe atrophy in Down syndrome along the Alzheimer’s disease continuum (odnośnik otworzy się w nowym oknie)

Autorzy: Benjamin J Buehner, Alejandra O Morcillo-Nieto, Sara E Zsadanyi, Mateus Rozalem Aranha, José Enrique Arriola-Infante, Lídia Vaqué-Alcázar, Javier Arranz, Íñigo Rodríguez-Baz, Lucia Maure Blesa, Laura Videla, Isabel Barroeta, Laura Del Hoyo Soriano, Bessy Benejam, Susana Fernández, Aida Sanjuan Hernandez, Nuria Bargalló, Sofía González-Ortiz, Sandra Giménez, Robin de Flores, Paul A Yush
Opublikowane w: Brain, Numer 148, 2025, Strona(/y) 2509-2521, ISSN 0006-8950
Wydawca: Oxford University Press
DOI: 10.1093/brain/awaf133

Cortical microstructure in primary progressive aphasia: a multicenter study (odnośnik otworzy się w nowym oknie)

Autorzy: Ignacio Illán-Gala; Victor Montal; Sergi Borrego-Écija; Maria Luisa Mandelli; Neus Falgàs; Ariane E. Welch; Jordi Pegueroles; Miguel Santos-Santos; Alexandre Bejanin; Daniel Alcolea; Oriol Dols-Icardo; Olivia Belbin; Mª. Belén Sánchez-Saudinós; Nuria Bargalló; Sofía González-Ortiz; Albert Lladó; Rafael Blesa; Bradford C. Dickerson; Howard J. Rosen; Bruce L. Miller; Alberto Lleó; Maria
Opublikowane w: Alzheimer's research & therapy, Numer 14, 2022, Strona(/y) 27, ISSN 1758-9193
Wydawca: BioMed Central
DOI: 10.1186/s13195-022-00974-0

Overview of methods and available tools used in complex brain disorders (odnośnik otworzy się w nowym oknie)

Autorzy: Loukas Ilias, George Doukas, Michael Kontoulis, Konstantinos Alexakis, Ariadni Michalitsi-Psarrou, Christos Ntanos, Dimitris Askounis
Opublikowane w: Open Research Europe, Numer 3, 2024, Strona(/y) 152, ISSN 2732-5121
Wydawca: European Commission
DOI: 10.12688/openreseurope.16244.1

Plasma glial fibrillary acidic protein and neurofilament light chain for the diagnostic and prognostic evaluation of frontotemporal dementia (odnośnik otworzy się w nowym oknie)

Autorzy: Zhu, Nuole; Santos-Santos, Miguel; Illán-Gala, Ignacio; Montal, Victor; Estellés, Teresa; Barroeta, Isabel; Altuna, Miren; Arranz, Javier; Muñoz, Laia; Belbin, Olivia; Sala, Isabel; Sánchez-Saudinós, Maria Belén; Subirana, Andrea; Videla, Laura; Pegueroles, Jordi; Blesa, Rafael; Clarimón, Jordi; Carmona-Iragui, Maria; Fortea, Juan; Lleó, Alberto; Alcolea, Daniel
Opublikowane w: Translational Neurodegeneration, Numer 10, 2021, Strona(/y) 50, ISSN 2047-9158
Wydawca: Springer Nature
DOI: 10.1186/s40035-021-00275-w

Sleep Apnea, Hypoxia, and Pain (odnośnik otworzy się w nowym oknie)

Autorzy: Elissaios Karageorgiou, Athanasia Giannopoulou, Klimentini E. Karageorgiou, Anthony G. Doufas
Opublikowane w: Current Sleep Medicine Reports, Numer 11, 2025, ISSN 2198-6401
Wydawca: Springer Science and Business Media LLC
DOI: 10.1007/s40675-025-00327-x

The overlooked trio: sleep duration, sampling time and physical exercise alter levels of olink-assessed blood biomarkers of cardiovascular risk (odnośnik otworzy się w nowym oknie)

Autorzy: Luiz Eduardo Mateus Brandão, Lei Zhang, Anastasia Grip, Mun-Gwan Hong, Emil Kåks, Rui Benfeitas, Fjola Sigurdardottir, Kaj Blennow, Henrik Zetterberg, Daniel Espes, Torbjørn Omland, Payam Emami Khoonsari, Christian Benedict, Jonathan Cedernaes
Opublikowane w: Biomarker Research, Numer 13, 2025, ISSN 2050-7771
Wydawca: Springer Science and Business Media LLC
DOI: 10.1186/s40364-025-00776-0

Mechanisms Involved in Epileptogenesis in Alzheimer’s Disease and Their Therapeutic Implications (odnośnik otworzy się w nowym oknie)

Autorzy: Miren Altuna; Gonzalo Olmedo-Saura; María Carmona-Iragui; Juan Fortea
Opublikowane w: International Journal of Molecular Sciences, Vol 23, Iss 8, p 4307 (2022), Numer 41, 2022, ISSN 1422-0067
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms23084307

Effects of storage conditions on the stability of blood-based markers for the diagnosis of Alzheimer’s disease (odnośnik otworzy się w nowym oknie)

Autorzy: Andrea Mansilla; Marina Canyelles; Rosa Ferrer; Javier Arranz; Íñigo Rodríguez-Baz; Nuole Zhu; Sara Rubio-Guerra; Shaimaa El Bounasri; Oriol Sánchez; Soraya Torres; Juan Fortea; Alberto Lleó; Daniel Alcolea; Mireia Tondo
Opublikowane w: Clinical chemistry and laboratory medicine, Numer 61, 2023, Strona(/y) 1580–1589, ISSN 1434-6621
Wydawca: Walter de Gruyter GmbH & Co. KG
DOI: 10.1515/cclm-2023-0245

Cross-sectional versus longitudinal cognitive assessments for the diagnosis of symptomatic Alzheimer's disease in adults with Down syndrome (odnośnik otworzy się w nowym oknie)

Autorzy: Videla, Laura; Benejam, Bessy; Carmona-Iragui, María; Barroeta, Isabel; Fernández, Susana; Arranz, Javier; Azzahchi, Sumia Elbachiri; Altuna, Miren; Padilla, Concepción; Valldeneu, Silvia; Pegueroles, Jordi; Montal, Víctor; Aranha, Mateus Rozalem; Vaqué-Alcázar, Lídia; Iulita, Maria Florencia; Alcolea, Daniel; Bejanin, Alexandre; Videla, Sebastià; Blesa, Rafael; Lleó, Alberto; Fortea, Jua
Opublikowane w: Alzheimer's & Dementia, Numer 19, 2023, Strona(/y) 3916–3925, ISSN 1552-5260
Wydawca: Elsevier BV
DOI: 10.1002/alz.13073

Data analytics for research on complex brain disorders (odnośnik otworzy się w nowym oknie)

Autorzy: Michail Kontoulis, George Doukas, Theodosios Pountridis, Loukas Ilias, George Ladikos, Vaggelis Lamrpou, Kostantinos Alexakis, Dimitris Askounis, Christos Ntanos
Opublikowane w: Open Research Europe, Numer 4, 2024, Strona(/y) 246, ISSN 2732-5121
Wydawca: Open Research Europe
DOI: 10.12688/openreseurope.18505.1

Cortical microinfarcts in adults with Down syndrome assessed with 3T‐MRI (odnośnik otworzy się w nowym oknie)

Autorzy: Mateus Rozalem Aranha, Victor Montal, Hilde van den Brink, Jordi Pegueroles, Maria Carmona‐Iragui, Laura Videla, Lucia Maure Blesa, Bessy Benejam, Javier Arranz, Sílvia Valldeneu, Isabel Barroeta, Susana Fernández, Laia Ribas, Daniel Alcolea, Sofía González‐Ortiz, Núria Bargalló, Geert Jan Biessels, Rafael Blesa, Alberto Lleó, Artur Martins Coutinho, Cláudia Costa Leite, Alexandre Beja
Opublikowane w: Alzheimer's & Dementia, Numer 20, 2024, Strona(/y) 3906-3917, ISSN 1552-5260
Wydawca: Elsevier BV
DOI: 10.1002/alz.13797

The potential role of CGRP in synuclein-associated neurodegenerative disorders (odnośnik otworzy się w nowym oknie)

Autorzy: Athanasia Alexoudi, Vincenzo Donadio, Elissaios Karageorgiou
Opublikowane w: Frontiers in Neuroscience, Numer 18, 2024, ISSN 1662-453X
Wydawca: Frontiers Media SA
DOI: 10.3389/fnins.2024.1479830

Characterization of white matter hyperintensities in Down syndrome (odnośnik otworzy się w nowym oknie)

Autorzy: Alejandra O. Morcillo‐Nieto, Sara E. Zsadanyi, Jose E. Arriola‐Infante, Maria Carmona‐Iragui, Victor Montal, Jordi Pegueroles, Mateus Rozalem Aranha, Lídia Vaqué‐Alcázar, Concepción Padilla, Bessy Benejam, Laura Videla, Isabel Barroeta, Susana Fernandez, Miren Altuna, Sandra Giménez, Sofía González‐Ortiz, Núria Bargalló, Laia Ribas, Javier Arranz, Soraya Torres, Maria Florencia
Opublikowane w: Alzheimer's & Dementia, Numer 20, 2025, Strona(/y) 6527-6541, ISSN 1552-5260
Wydawca: Elsevier BV
DOI: 10.1002/alz.14146

Cortical microstructural changes predict tau accumulation and episodic memory decline in older adults harboring amyloid (odnośnik otworzy się w nowym oknie)

Autorzy: Geoffroy Gagliardi, Elena Rodriguez-Vieitez, Victor Montal, Jorge Sepulcre, Ibai Diez, Cristina Lois, Bernard Hanseeuw, Aaron P. Schultz, Michael J. Properzi, Kathryn V. Papp, Gad A. Marshall, Juan Fortea, Keith A. Johnson, Reisa A. Sperling, Patrizia Vannini
Opublikowane w: Communications Medicine, Numer 3, 2023, ISSN 2730-664X
Wydawca: Nature Portfolio
DOI: 10.1038/s43856-023-00324-7

Acute Sleep Loss Increases Circulating Morning Levels of Two MicroRNAs Implicated in Neurodegenerative Disease in Healthy Young Men (odnośnik otworzy się w nowym oknie)

Autorzy: Lei Zhang, Anastasia Grip, Daisy Hjelmqvist, Christian Benedict, Luiz Eduardo Mateus Brandão, Jonathan Cedernaes
Opublikowane w: Journal of Cellular and Molecular Medicine, Numer 29, 2025, ISSN 1582-1838
Wydawca: Wiley-Blackwell
DOI: 10.1111/jcmm.70523

Potential predictive value of repetitive transcranial magnetic stimulation before chronic cortical stimulation for epilepsia partialis continua (odnośnik otworzy się w nowym oknie)

Autorzy: Rhys Potter, A.; Hallal-Peche, F.; Stavropoulos, I.; Price, L.; Jimenez-Jimenez, D.; Freigang, S. et al.
Opublikowane w: Brain stimulation, Numer 16, 2023, Strona(/y) 71–74, ISSN 1935-861X
Wydawca: Elsevier BV
DOI: 10.1016/j.brs.2023.01.836

Associations of Microbleeds and Their Topography With Imaging and CSF Biomarkers of Alzheimer Pathology in Individuals With Down Syndrome (odnośnik otworzy się w nowym oknie)

Autorzy: Sara E. Zsadanyi, Alejandra O. Morcillo-Nieto, Mateus R. Aranha, Irina Aragón, José E. Arriola-Infante, Lídia Vaqué-Alcázar, Victor Montal, Jordi Pegueroles, Javier Arranz, Íñigo Rodríguez-Baz, Lucia M. Blesa, Laura Videla, Isabel Barroeta, Laura del Hoyo Soriano, Bessy Benejam, Susana Fernández, Aida S. Hernandez, Nuria Bargallo, Sofía González-Ortiz, Sandra Giménez, Daniel Alcolea, O
Opublikowane w: Neurology, Numer 103, 2024, ISSN 0028-3878
Wydawca: Lippincott Williams & Wilkins Ltd.
DOI: 10.1212/wnl.0000000000209676

Basal forebrain atrophy along the Alzheimer's disease continuum in adults with Down syndrome (odnośnik otworzy się w nowym oknie)

Autorzy: Rozalem Aranha, Mateus; Iulita, Maria Florencia; Montal, Victor; Pegueroles, Jordi; Bejanin, Alexandre; Vaqué-Alcázar, Lídia; Grothe, Michel J.; Carmona-Iragui, Maria; Videla, Laura; Benejam, Bessy; Arranz, Javier; Padilla, Concepción; Valldeneu, Sílvia; Barroeta, Isabel; Altuna, Miren; Fernández, Susana; Ribas, Laia; Valle-Tamayo, Natalia; Alcolea, Daniel; González-Ortiz, Sofía; Bargalló
Opublikowane w: Alzheimer's & Dementia, Numer 19, 2023, Strona(/y) 4817–4827, ISSN 1552-5260
Wydawca: Elsevier BV
DOI: 10.1002/alz.12999

Predicting Behind-the-Wheel Driving Behavior in Parkinson Disease Through Motor and Cognitive Testing in Outpatient Clinics (odnośnik otworzy się w nowym oknie)

Autorzy: Nikolaos Andronas, Elissaios Karageorgiou, Ion N Beratis, Stella Fragkiadaki, Dionysia Kontaxopoulou, Dimosthenis Pavlou, Eleonora Papadimitriou, George Yannis, Alexandra Economou, Leonidas Stefanis, Sokratis Papageorgiou
Opublikowane w: International Journal of Geriatrics and Gerontology, Numer 9, 2025, ISSN 2577-0748
Wydawca: Gavin Publishers
DOI: 10.29011/2577-0748.100205

Missing Value Imputation Methods for Electronic Health Records (odnośnik otworzy się w nowym oknie)

Autorzy: Konstantinos Psychogyios; Loukas Ilias; Christos Ntanos; Dimitris Askounis
Opublikowane w: IEEE Access, Numer 11, 2023, Strona(/y) 21562–21574, ISSN 2169-3536
Wydawca: Institute of Electrical and Electronics Engineers Inc.
DOI: 10.1109/access.2023.3251919

MES-CoBraD D9.5 Business and Exploitation Plan – v1 (odnośnik otworzy się w nowym oknie)

Autorzy: George Stravodimos
Opublikowane w: 2022
Wydawca: The MES-CoBraD Project
DOI: 10.5281/zenodo.6473320

Libraries in the Research and Innovation Landscape (LIBER 2022) - Conference - MES-CoBraD Poster (odnośnik otworzy się w nowym oknie)

Autorzy: LIBER; HOLISTIC
Opublikowane w: 2022
Wydawca: LIBER
DOI: 10.5281/zenodo.7180887

Research Data Management in the MES-CoBraD project: what's in it for the research libraries? (odnośnik otworzy się w nowym oknie)

Autorzy: Blake, Oliver
Opublikowane w: LIBER Annual Conference, 2022
Wydawca: LIBER
DOI: 10.5281/zenodo.6806489

MES-CoBraD D4.2 Scientific Aims and Testable Hypotheses-v1 (odnośnik otworzy się w nowym oknie)

Autorzy: KCL
Opublikowane w: 2022
Wydawca: The MES-CoBraD Project
DOI: 10.5281/zenodo.6473259

MES-CoBraD D5.1 Data integration, harmonisation, sharing and security – v1 (odnośnik otworzy się w nowym oknie)

Autorzy: Engineering - Ingegneria Informatica S.p.A.
Opublikowane w: 2022
Wydawca: The MES-CoBraD Project
DOI: 10.5281/zenodo.6473275

Communication & Dissemination Plan (odnośnik otworzy się w nowym oknie)

Autorzy: Stravodimos, George
Opublikowane w: 2021
Wydawca: The MES-CoBraD Project
DOI: 10.5281/zenodo.5155585

D9.3 Promotional and informational material (odnośnik otworzy się w nowym oknie)

Autorzy: Stravodimos, George
Opublikowane w: 2021
Wydawca: The MES-CoBraD Project
DOI: 10.5281/zenodo.5547122

MES-CoBrad D8.3 Participant recruitment, Pre-existing RWD access, Prospective RWD acquisition and secure storage -v1 (odnośnik otworzy się w nowym oknie)

Autorzy: IR-HSCSP
Opublikowane w: 2022
Wydawca: The MES-CoBraD Project
DOI: 10.5281/zenodo.6473289

Project Manual – CoBraD RWD, Updated MES-CoBraD Protocols and Quality and Quantity (Q&Q) Evaluation (odnośnik otworzy się w nowym oknie)

Autorzy: Keret, Ophir
Opublikowane w: 2021
Wydawca: The MES-CoBraD Project
DOI: 10.5281/zenodo.5106495

D3.5 Establishment of External Advisory Board (odnośnik otworzy się w nowym oknie)

Autorzy: KCL
Opublikowane w: 2021
Wydawca: The MES-CoBraD Project
DOI: 10.5281/zenodo.5547100

D3.2 - Project Manual – CoBraD RWD, Updated MES-CoBraD Protocols and Quality and Quantity (Q&Q) Evaluation – v2 (odnośnik otworzy się w nowym oknie)

Autorzy: RMC
Opublikowane w: 2021
Wydawca: The MES-CoBraD Project
DOI: 10.5281/zenodo.5544020

D8.1 Report on the registration of the Studies (odnośnik otworzy się w nowym oknie)

Autorzy: Montal, Victor
Opublikowane w: 2021
Wydawca: The MES-CoBraD Project
DOI: 10.5281/zenodo.5547113

MES-CoBraD D2.3 The CoBraD ethical and regulatory framework (odnośnik otworzy się w nowym oknie)

Autorzy: Sergi Vazquez Maymir
Opublikowane w: 2022
Wydawca: The MES-CoBraD Project
DOI: 10.5281/zenodo.6473241

Intelligent Querying for Implementing Building Aggregation Pipelines (odnośnik otworzy się w nowym oknie)

Autorzy: Konstantinos Alexakis; Panagiotis Kapsalis; Zoi Mylona; Georgios Kormpakis; Evangelos Karakolis; Christos Ntanos; Dimitris Askounis
Opublikowane w: International Conference on Information, Intelligence, Systems & Applications (IISA), Numer 13, 2022, Strona(/y) 1-6, ISBN 978-1-6654-6390-4
Wydawca: IEEE
DOI: 10.1109/iisa56318.2022.9904384

Let the AI assisted medicine remain human Developing a care centered model of ethical decision making in AI based healthcare

Autorzy: Francesca Morpurgo, Carmela Occhipinti
Opublikowane w: Proceedings of the Italia Intelligenza Artificiale - Thematic Workshops, Numer Pisa, Italy, May 29-30, 2023, 2023, ISSN 1613-0073
Wydawca: CEUR

Sleep‐mediated cognitive assessment and sleep architecture associations for real‐world diagnostic phenotyping of neurocognitive disorders (odnośnik otworzy się w nowym oknie)

Autorzy: Karageorgiou, Elissaios; Sykara, Konstantina; Andronas, Nikolaos; Alexoudi, Athanasia; Devenopoulou, Zoe; Pitman, Julie; Karageorgiou, Klimentini E.
Opublikowane w: Alzheimer's & Dementia, Numer 19, 2023, Strona(/y) e076048, ISSN 1552-5260
Wydawca: Wiley
DOI: 10.1002/alz.076048

_an open-source research platform for integrated epilepsy-EEG data collection and analysis

Autorzy: I Stavropoulos, M Kontoulis, L Ilias, G Doukas, E Nianiou, M Pina, M Dolzan, F Benninger, S Gimenez Badia, A Glik, I Goldberg, E Karageorgiou, C Ntanos, O Keret, A Valentin
Opublikowane w: EPILEPSIA, Numer 64, 2023, Strona(/y) 59-59
Wydawca: WILEY

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