Cel Saccharomyces cerevisiae was selected as a model system due to its potential industrial interest. In this organism there are 3 acidic proteins present in the ribosome. The proteins were purified and polyclonal and monoclonal antibodies specific for each polypeptide were prepared. The genes encoding ribosomal proteins L44, L45 and L44' were cloned and strains lacking each one of the genes were obtained subsequently using gene disruption techniques. The defective strains were viable. The results have shown that the different acidic ribosomal proteins seem to play a similar role and can be substituted functionally among themselves. Dziedzina nauki natural sciencesbiological sciencesbiochemistrybiomoleculesproteins Program(-y) FP1-BAP - Multiannual research action programme (EEC) in the field of biotechnology (BAP), 1985-1989 Temat(-y) Data not available Zaproszenie do składania wniosków Data not available System finansowania CSC - Cost-sharing contracts Koordynator CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS Wkład UE Brak danych Adres Serrano 117 MADRID Hiszpania Zobacz na mapie Koszt całkowity Brak danych
