Optimisation of proton-electron double-resonance imaging and electron paramagnetic resonance imaging for in vivo detection of free radicals

Informacje na temat projektu

Identyfikator umowy o grant: FMBI960973

Data rozpoczęcia

Data zakończenia

Finansowanie w ramach

• Specific research and technological development programme in the field of the training and mobility of researchers, 1994-1998

Koszt całkowity Brak danych

Wkład UE Brak danych

Koordynowany przez

UNIVERSITY OF ABERDEEN
United Kingdom

Cel

This project is concerned with the development and optimisation of proton-electron double-resonance imaging (PEDRI), a technique which combines magnetic resonance imaging (MRI) with electron paramagnetic resonance (EPR) in order to image the distribution of free radicals in biological samples and in living animals. The project will explore the use of advanced radiofrequency EPR techniques in order to improve the sensitivity of PEDRI. In particular, the use of ultra-fast pulsed EPR irradiation will be investigated, since it offers a theoretical two-fold sensitivity advantage over continuous-wave EPR irradiation. Multi-tuned resonators for PEDRI will also be developed in combination with automatic frequency/matching controls to improve efficiency. Detailed comparisons between the different irradiation strategies will be made under a variety of experimental conditions, and optimum parameters for the use of these techniques to study free radicals in vivo will be determined.

Dziedzina nauki

• engineering and technology › electrical engineering, electronic engineering, information engineering › information engineering › telecommunications › radio technology › radio frequency
• engineering and technology › medical engineering › diagnostic imaging › magnetic resonance imaging

Program(-y)

• FP4-TMR - Specific research and technological development programme in the field of the training and mobility of researchers, 1994-1998

Temat(-y)

• 0302 - Post-doctoral research training grants
• TP15 - Instrumentation and Applied Physics

Zaproszenie do składania wniosków

Data not available

System finansowania

RGI - Research grants (individual fellowships)

Koordynator

UNIVERSITY OF ABERDEEN

• Wkład UE: Brak danych
• Adres: Foresterhill ; AB25 2ZD ABERDEEN ; Zjednoczone Królestwo
• Koszt całkowity: Brak danych

Uczestnicy (1)

Not available

Włochy

• Wkład UE: Brak danych
• Koszt całkowity: Brak danych