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Zawartość zarchiwizowana w dniu 2024-04-30

Epidemiology and pathogenesis of porcine post-weaning multisystemic wasting syndrome

Cel



Research objectives and content
The main objective is to investigate the pathogenesis and epidemiology of PMWS, and to determine the causal link of porcine circovirus (PCV) with this new syndrome. It includes clinicopathological study of natural cases and experimental reproduction of PMWS by inoculation of PCV, the development of techniques for detection of PCV, and collection of epidemiological information in PMWS-affected farms.Technical milestones are standardisation of an immunocytochemical technique for detection of PCV-antigen, and development of a PCR technique for detection of PCV genome. Sequencing of PMWS-related PCV will allow design ofspecific DNA probes to differentiate PCV derived from PK-15 cells and from PMWS cases. A ELISA technique for PCV antibodies will be standardised, and well as immunocytochemical techniques for porcine monocyte-macrophage markers for its use in formalin-fixed, paraffin-embedded tissues.
Training content (objective, benefit and expected impact)
The candidate will be Doctorate, and could present at the exam for Diplomat of the ECVP. Trained candidate will be able to work as a pathologist, and to conduct research on animal infectious diseases. Links with industry / industrial relevance (22)
The design of vaccines to prevent PCV-infection may be of interest for the vaccine-industry. Fort Dodge Veterinaria traces the host institution for collaborative research on this disease.

Dziedzina nauki (EuroSciVoc)

Program(-y)

Temat(-y)

Zaproszenie do składania wniosków

Brak dostępnych danych

System finansowania

RGI - Research grants (individual fellowships)

Koordynator

Universitat Autonoma de Barcelona
Wkład UE
Brak danych
Adres

08193 Barcelona
Hiszpania
Koszt całkowity
Brak danych