PHAGENET: PHAge GEnetic NETworking in the microbiome

Informazioni relative al progetto

PHAGENET

ID dell’accordo di sovvenzione: 101001684

DOI

10.3030/101001684

Data della firma CE 8 Aprile 2021

Data di avvio 1 Luglio 2021

Data di completamento 30 Giugno 2027

Finanziato da

• EXCELLENT SCIENCE - European Research Council (ERC)

Costo totale

€ 1 999 988,00

Contributo UE

€ 1 999 988,00

Coordinato da

UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK
Ireland

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Open Research Data Pilot (1)

Data Management Plan (DMP)

Data Management Plan DMP

Pubblicazioni

Peer reviewed articles (16)

Social anxiety disorder-associated gut microbiota increases social fear

Autori: Nathaniel L. Ritz, Marta Brocka, Mary I. Butler, Caitlin S. M. Cowan, Camila Barrera-Bugueño, Christopher J. R. Turkington, Lorraine A. Draper, Thomaz F. S. Bastiaanssen, Valentine Turpin, Lorena Morales, David Campos, Cassandra E. Gheorghe, Anna Ratsika, Virat Sharma, Anna V. Golubeva, Maria R. Aburto, Andrey N. Shkoporov, Gerard M. Moloney, Colin Hill, Gerard Clarke, David A. Slattery, Timothy
Pubblicato in: PNAS, Numero 2023, 2023, ISSN 1091-6490
Editore: NAS
DOI: 10.1073/pnas.2308706120

Draft Genome Sequence of Legionella pneumophila subsp. pneumophila Strain DSM 25199

Autori: Neda Nezam-Abadi, Christopher J. R. Turkington, Lorraine A. Draper, Andrey N. Shkoporov, R. Paul Ross, Colin Hill
Pubblicato in: Microbiology Resource Announcements, Numero 2023, 2023, ISSN 2576-098X
Editore: American Society of Microbiology
DOI: 10.1128/mra.00048-23

Adaptations in gut Bacteroidales facilitate stable co-existence with their lytic bacteriophages

Autori: Adrián Cortés-Martín, Colin Buttimer, Jessie L. Maier, Ciara A. Tobin, Lorraine A. Draper, R. Paul Ross, Manuel Kleiner, Colin Hill, Andrey N. Shkoporov
Pubblicato in: Gut Microbes, Numero 17, 2025, ISSN 1949-0976
Editore: Landes Bioscience
DOI: 10.1080/19490976.2025.2507775

Transmission and dynamics of mother-infant gut viruses during pregnancy and early life

Autori: Sanzhima Garmaeva, Trishla Sinha, Anastasia Gulyaeva, Nataliia Kuzub, Johanne E. Spreckels, Sergio Andreu-Sánchez, Ranko Gacesa, Arnau Vich Vila, Siobhan Brushett, Marloes Kruk, null null, Aafje Dotinga, Sanne Gordijn, Soesma Jankipersadsing, Ank de Jonge, Marlou L. A. de Kroon, Gerard H. Koppelman, Lilian L. Peters, Jelmer R. Prins, Sijmen A. Reijneveld, Morris A. Swertz, Henkjan J. Verkade, Jac
Pubblicato in: Nature Communications, Numero 15, 2024, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-024-45257-4

Structural atlas of the most abundant human gut virus

Autori: Bayfield, O.; Shkoporov, A.N.; Yutin, N., Khokhlova, E., Smith, J.; Hawkins, D.; Koonin, E.; Hill, C.; Anston, A.
Pubblicato in: Nature, Numero 2023, 2023, Pagina/e 409–416, ISSN 2693-5015
Editore: Springer Nature
DOI: 10.1038/s41586-023-06019-2

Bacteriophages of the Order Crassvirales: What Do We Currently Know about This Keystone Component of the Human Gut Virome?

Autori: Linda Smith, Ekaterina Goldobina, Bianca Govi, Andrey N. Shkoporov
Pubblicato in: Biomolecules, 2023, ISSN 2218-273X
Editore: MDPI
DOI: 10.3390/biom13040584

Temperate bacteriophages infecting the mucin-degrading bacterium Ruminococcus gnavus from the human gut

Autori: Colin Buttimer,Ekaterina V. Khokhlova,Lisa Stein,Cara M. Hueston,Bianca Govi,Lorraine A. Draper,R. Paul Ross,Andrey N. Shkoporovb
Pubblicato in: Gut Microbes, 2022, ISSN 0307-1022
Editore: Methuen
DOI: 10.1080/19490976.2023.2194794

Dynamic nature of viral and bacterial communities in human faeces

Autori: Andrey N. Shkoporov, Orla O'Regan, Linda Smith, Ekaterina V. Khokhlova, Lorraine A. Draper, R. Paul Ross, Colin Hill
Pubblicato in: iScience, 2024, ISSN 2589-0042
Editore: Elsevier
DOI: 10.1016/j.isci.2023.108778

The gut virome is associated with stress-induced changes in behaviour and immune responses in mice

Autori: Nathaniel L. Ritz, Lorraine A. Draper, Thomaz F. S. Bastiaanssen, Christopher J. R. Turkington, Veronica L. Peterson, Marcel van de Wouw, Klara Vlckova, Christine Fülling, Katherine E. Guzzetta, Aurelijus Burokas, Hugh Harris, Marion Dalmasso, Fiona Crispie, Paul D. Cotter, Andrey N. Shkoporov, Gerard M. Moloney, Timothy G. Dinan, Colin Hill, John F. Cryan
Pubblicato in: Nature Microbiology, Numero 9, 2024, Pagina/e 359-376, ISSN 2058-5276
Editore: Springer Science and Business Media LLC
DOI: 10.1038/s41564-023-01564-y

Interpersonal variability of the human gut virome confounds disease signal detection in IBD

Autori: Stephen R. Stockdale, Andrey N. Shkoporov, Ekaterina V. Khokhlova, Karen M. Daly, Siobhan A. McDonnell, Orla O’ Regan, James A. Nolan, Thomas D. S. Sutton, Adam G. Clooney, Feargal J. Ryan, Donal Sheehan, Aonghus Lavelle, Lorraine A. Draper, Fergus Shanahan, R. Paul Ross & Colin Hill
Pubblicato in: Communications Biology, Numero 2023, 2023, ISSN 2399-3642
Editore: Springer Nature
DOI: 10.1038/s42003-023-04592-w

Large-scale capsid-mediated mobilisation of bacterial genomic DNA in the gut microbiome

Autori: Tatiana Borodovich, Colin Buttimer, Jason S. Wilson, Pavol Bardy, Muireann Smith, Conor Hill, Ekaterina V. Khokhlova, Matthew Harte, Bianca Govi, Paul C. M. Fogg, Colin Hill, Andrey N. Shkoporov
Pubblicato in: Nature Communications, 2026, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-026-68726-4

Abolishment of morphology‑based taxa and change to binomial species names: 2022 taxonomy update of the ICTV bacterial viruses subcommittee

Autori: Turner D, Shkoporov AN, Lood C, Millard AD, Dutilh BE, Alfenas-Zerbini P, van Zyl LJ, Aziz RK, Oksanen HM, Poranen MM, Kropinski AM, Barylski J, Brister JR, Chanisvili N, Edwards RA, Enault F, Gillis A, Knezevic P, Krupovic M, Kurtböke I, Kushkina A, Lavigne R, Lehman S, Lobocka M, Moraru C, Moreno Switt A, Morozova V, Nakavuma J, Reyes Muñoz A, Rūmnieks J, Sarkar BL, Sullivan MB, Uchiyama J, W
Pubblicato in: Archives of Virology, Numero 2023, 2023, ISSN 0304-8608
Editore: Springer Verlag
DOI: 10.1007/s00705-022-05694-2

Social fear extinction susceptibility is associated with Microbiota-Gut-Brain axis alterations

Autori: Nathaniel L. Ritz, Thomaz F.S. Bastiaanssen, Caitlin S.M. Cowan, Linda Smith, Nigel Theune, Marta Brocka, Eibhlís M. Myers, Rachel D. Moloney, Gerard M. Moloney, Andrey N. Shkoporov, Lorraine A. Draper, Colin Hill, Timothy G. Dinan, David A. Slattery, John F. Cryan
Pubblicato in: Brain, Behavior, and Immunity, Numero 120, 2024, Pagina/e 315-326, ISSN 0889-1591
Editore: Academic Press
DOI: 10.1016/j.bbi.2024.06.009

Bacteriophages mobilize bacterial defense systems via lateral transduction

Autori: Xu Kuang, Jamie Gorzynski, Marie Touchon, Andrey Shkoporov, Eduardo P. C. Rocha, J. Ross Fitzgerald, John Chen, Jakob T. Rostøl, José R. Penadés
Pubblicato in: Science Advances, Numero 12, 2026, ISSN 2375-2548
Editore: American Association for the Advancement of Science (AAAS)
DOI: 10.1126/sciadv.adx5749

Mutualistic interplay between bacteriophages and bacteria in the human gut

Autori: Shkoporov AN, Turkington CJ, Hill C.
Pubblicato in: Nature Reviews Microbiology, 2022, ISSN 1740-1534
Editore: Springer Nature
DOI: 10.1038/s41579-022-00755-4

Bacterial Viruses Subcommittee and Archaeal Viruses Subcommittee of the ICTV: update of taxonomy changes in 2021

Autori: Krupovic M, Turner D, Morozova V, Dyall-Smith M, Oksanen HM, Edwards R, Dutilh BE, Lehman SM, Reyes A, Baquero DP, Sullivan MB, Uchiyama J, Nakavuma J, Barylski J, Young MJ, Du S, Alfenas-Zerbini P, Kushkina A, Kropinski AM, Kurtböke I, Brister JR, Lood C, Sarkar BL, Yigang T, Liu Y, Huang L, Wittmann J, Chanishvili N, van Zyl LJ, Rumnieks J, Mochizuki T, Jalasvuori M, Aziz RK, Łobocka M, Stedma
Pubblicato in: Archives of Virology, Numero 2021, 2021, ISSN 1432-8798
Editore: Springer Nature
DOI: 10.1007/s00705-021-05205-9

Other (1)

Prevalent Gut Phages Encode Modular Adhesins Mediating Epithelial Binding and Endoplasmic Reticulum Trafficking

Autori: Gábor Apjok, Tóbiás Sári, Orsolya Méhi, András Asbóth, Lilla Barna, Dóra Sala, Ilona Gróf, Bálint Márk Vásárhelyi, Szilvia Juhász, Csaba Pál, Péter Horváth, Ede Migh, György Schneider, Colin Hill, Mária Deli, Andrey Shkoporov, Bálint Kintses
Pubblicato in: bioRxiv, 2026
Editore: openRxiv
DOI: 10.64898/2026.02.02.702849