Rapid European SARS-CoV-2 Emergency research Response

Rezultaty

2-Reports on the coordinated development and operational management of the European COVID-19 Adaptive Platform Trials

This report will include but is not limited to key recommendations to implement the highlevel strategy defined by the TCB development of new platforms major amendments to existing platforms introduction of new therapeutic domains introduction of new arms development of platforms for prevention or vaccines design of interventional trials based on observational studies expansion to new countries including capacity building for interested sites site selection etc The report will describe the framework that will allow complementarity between trials with regard to the implementation of the highlevel strategy This report will also include the detailed plan on data harmonization between trials to allow common analysis of core data sets

Plan for coordination and collaboration with other SARS-COV-2 projects: update 1

First update of D13

SOPs to standardise and harmonise diagnostic test protocols

SOPs to standardise and harmonise diagnostic test protocols for detection of the SARS-CoV-2 and/or exclusion of other respiratory viral and bacterial pathogens.

Final report on the readiness of the networks

Report on the additional qualitative work on the readiness of the networks

Protocol for healthcare professionals survey

Understanding healthcare worker views on the management of the COVID-19 pandemic can inform hospital strategies for implementing IPC guidelines, inform communication strategies and can inform strategies to protect healthcare worker physical and psychological health.

1-Reports on the coordinated development and operational management of the European COVID-19 Adaptive Platform Trials

This report will include, but is not limited to key recommendations to implement the high-level strategy defined by the TCB - development of new platforms, major amendments to existing platforms, introduction of new therapeutic domains, introduction of new arms, development of platforms for prevention or vaccines, design of interventional trials based on observational studies, expansion to new countries including capacity building for interested sites, site selection etc. The report will describe the framework that will allow complementarity between trials with regard to the implementation of the high-level strategy. This report will also include the detailed plan on data harmonization between trials to allow common analysis of core data sets.

2-Report on the strategic vision and deployment of the European COVID-19 Adaptive Platform Trials

This report will include but is not limited to COVID19 international clinical research benchmarking and landscape analysis clinical research gaps for Europe recommendations on priorities in terms of platform trials therapeutic domains and arms It will also include a report on lessonslearnt from OCToPUs

First study report of finalized analysis in one treatment domain
Study updates and summaries

Regular study updates will allow to keep all partners informed about study progress Dates of publication cannot be specified as patient enrollment depends on the evolution of the pandemic

Plan for coordination and collaboration with other SARS-COV-2 projects: update 2

Second update of D13

UK approved protocol for adapted PRUDENCE trial

RECOVER will seek rapid UK approval of the protocol governing the adapted PRUDENCE trial as originally developed in the VALUEDx project

Healthcare professionals survey report

Interview approaches will be pragmatic and adapted to consider the immediate needs of healthcare professionals and to minimise burden.

1-Report on the strategic vision and deployment of the European COVID-19 Adaptive Platform Trials

This report will include, but is not limited to COVID-19 international clinical research benchmarking and landscape analysis, clinical research gaps for Europe, recommendations on priorities in terms of platform trials, therapeutic domains and arms. It will also include a report on lessons-learnt from OCToPUs.

Plan for coordination and collaboration with other SARS-COV-2 projects

Report to include plan for regular meetings to update on each other's progress, concrete plan on use of common protocols and to ensure harmonization of data collection and coordinated modelling, establishment of inter-project working groups, plan on integration of social sciences capacities and sharing research findings on the dedicated platform (Health Policy Platform/research for policy action).

Results of etiologic diagnosis

Results of etiologic diagnosis on the samples from patients included in the clinical trials on the SARS-CoV-2 in WP2 and WP3.

Final study report
Feasibility questionnaire

To facilitate the site selection process, a feasibility questionnaire will be sent that aims to collect study-specific information e.g. on in-house methods and possibilities to implement protocols and methods to detect SARS-COV-2.

Validation report on PCR based test

Validation report on ready-to-use in-house PCR based test to be used in the clinical trial.

Approved protocol for the observational study

This protocol for a prospective, non-randomized observational study of CA-ARTI in primary care will include capability to register patients with CA-ARTI in primary care in up to 20 countries, capturing data about the presentation, management, risk factors and (reasons for) suspicion for SARS-CoV-2, treatment, routine investigations performed, outcome of tests, taking a throat and/or nasal swab for research purposes, and capturing clinical outcomes and patient and HCP perceptions.

Monthly interim findings from social science related activities

In order to rapidly generate evidence for public health and other decision makers, RECOVER will include a brief survey for patients and healthcare workers. Information will be rapidly processed and interim findings fed back to decision makers.

Policy brief reporting outcomes from the public survey

Interim reports will help guide communication strategies and clinical research planning at local and national levels

Communication outputs

We will share our (preliminary) results with public health authorities, policy makers and healthcare workers via regular policy briefs and healthcare briefs, summarizing our findings in a concise manner. There is a wealth of other research response efforts being implemented by the wider European infectious diseases research response community. Many of our partners working in Europe, but also in regions outside of Europe (e.g. Africa and Asia) have informed us of their efforts and offered linking their efforts to those conducted in RECOVER. We will reach out to patient organisations such as the International Alliance of Patients’ Organisations (IAPO and European Lung Foundation (ELF) to assess their information needs and how we can best serve these out of RECOVER. RECOVER will target the media with press releases at important time points and milestones. RECOVER's communication activities include the design of a visual identity, online presence (website, social media...), open access publications, news updates, infographics and brochures.

Study protocol MERMAIDS 2.0

For Phase II, we will adapt the existing MERMAIDS-ARI protocol (part I) to capture additional aspects relevant to SARS-CoV-2 infections, collect more and targeted biological sampling of confirmed SARS-CoV-2 infections needed for WP5 and WP6, and to enroll children (non-eligible in part I).

Second overall study report
Report on tools, methodologies and sustainability model for Adaptive Platform Trial design and management, including blueprint for the creation and management of Adaptive Platform Trials in other disease areas beyond COVID-19

This report will include but is not limited to tools for the design of platform trials including statistical methods master protocol template selection of outcome measures and endpoints etc tools for the management of platform trials including sponsorship IP pharmacovigilance data management data sharing cost and business model etc

Protocols for collection and transport of specimens

This deliverable includes sampling SOPs with details on the choice of samples and sampling collection time points that should be collected in line with the study objectives and SOPs with detailed instructions on sample processing locally, storage and transfer of samples to the central laboratory.

Final study report on social science

Final study report on the social science output

Publikacje

Population-based screening in a municipality after a primary school outbreak of the SARS-CoV-2 Alpha variant, the Netherlands, December 2020–February 2021

Autorzy: van Beek et al
Opublikowane w: PLOS One, 2022
Wydawca: PLOS
DOI: 10.1371/journal.pone.0276696

Attitudes towards booster, testing and isolation, and their impact on COVID-19 response in winter 2022/2023 in France, Belgium, and Italy: a cross-sectional survey and modelling study

Autorzy: De Meijere et al.
Opublikowane w: The Lancet Regional Health - Europe, 2023
Wydawca: Elsevier
DOI: 10.1016/j.lanepe.2023.100614

Conducting rapid qualitative interview research during the COVID-19 pandemic—Reflections on methodological choices

Autorzy: Marta Wanat, Aleksandra J. Borek, Caitlin Pilbeam, Sibyl Anthierens, and Sarah Tonkin-Crine
Opublikowane w: Frontiers in Sociology, 2022
Wydawca: Frontiers
DOI: 10.3389/fsoc.2022.953872

Highlighting socio-economic constraints on mobility reductions during COVID-19 restrictions in France can inform effective and equitable pandemic response

Autorzy: Eugenio Valdano, Jonggul Lee, Shweta Bansal, Stefania Rubrichi, Vittoria Colizza
Opublikowane w: Journal of Travel Medicine, 2021
Wydawca: Oxford Academic
DOI: 10.1093/jtm/taab045

Clinical characteristics, risk factors and outcomes in patients with severe COVID-19 registered in the ISARIC WHO clinical characterisation protocol: a prospective, multinational, multicentre, observational study

Autorzy: Reyes, Luis Felipe et al
Opublikowane w: ERJ Open Research, 2022
Wydawca: ERS
DOI: 10.1183/23120541.00552-2021

Conformational dynamics of the Beta and Kappa SARS-CoV-2 spike proteins and their complexes with ACE2 receptor revealed by cryo-EM

Autorzy: Yifan Wang, Cong Xu, Yanxing Wang, Qin Hong, Chao Zhang, Zuyang Li, Shiqi Xu, Qinyu Zuo, Caixuan Liu, Zhong Huang, Yao Cong
Opublikowane w: Nature Communications, Numer Article number: 7345 (2021), 2021
Wydawca: Springer Nature
DOI: 10.1038/s41467-021-27350-0

Divergent SARS CoV-2 Omicron-reactive T- and B cell responses in COVID-19 vaccine recipients

Autorzy: GeurtsvanKessel CH, Geers D, Schmitz KS, Mykytyn AZ, Lamers MM, Bogers S, Scherbeijn S, Gommers L, Sablerolles RSG, Nieuwkoop NN, Rijsbergen LC, van Dijk LLA, de Wilde J, Alblas K, Breugem TI, Rijnders BJA, de Jager H, Weiskopf D, van der Kuy PHM, Sette A, Koopmans MPG, Grifoni A, Haagmans BL, de Vries RD
Opublikowane w: Sci Immunol, 2022
Wydawca: AAAS
DOI: 10.1126/sciimmunol.abo2202

Enhanced fitness of SARS-CoV-2 variant of concern Alpha but not Beta

Autorzy: Ulrich L, Halwe NJ, Taddeo A, Ebert N, Schön J, Devisme C, Trüeb BS, Hoffmann B, Wider M, Fan X, Bekliz M, Essaidi-Laziosi M, Schmidt ML, Niemeyer D, Corman VM, Kraft A, Godel A, Laloli L, Kelly JN, Calderon BM, Breithaupt A, Wylezich C, Berenguer Veiga I, Gultom M, Osman S, Zhou B, Adea K, Meyer B, Eberhardt CS, Thomann L, Gsell M, Labroussaa F, Jores J, Summerfield A, Drosten C, Eckerle IA, We
Opublikowane w: Nature, 2022
Wydawca: Springer Nature
DOI: 10.1038/s41586-021-04342-0

The value of open-source clinical science in pandemic response: lessons from ISARIC

Autorzy: The ISARIC Clinical Characterisation Group
Opublikowane w: Lancet Infectious Diseases, 2021
Wydawca: Elsevier
DOI: 10.1016/s1473-3099(21)00565-x

Methodological and ethical considerations when conducting qualitative interview research with healthcare professionals: reflections and recommendations as a result of a pandemic

Autorzy: Pilbeam, C., Anthierens, S., Vanderslott, S., Tonkin-Crine, S., & Wanat, M.
Opublikowane w: International Journal of Qualitative Methods, 2022
Wydawca: Sage Journals
DOI: 10.1177/16094069221077763

Transmission of SARS-CoV-2 within households: a remote prospective cohort study in European countries

Autorzy: Janneke D. M. Verberk, Marieke L. A. de Hoog, Ilse Westerhof, Sam van Goethem, Christine Lammens, Greet Ieven, Erwin de Bruin, Dirk Eggink, Julia A. Bielicki, Samuel Coenen, Janko van Beek, Marc J. M. Bonten, Herman Goossens & Patricia C. J. L. Bruijning-Verhagen
Opublikowane w: European Journal of Epidemiology, 2022
Wydawca: Springer
DOI: 10.1007/s10654-022-00870-9

Heterogeneous Treatment Effects of Therapeutic-Dose Heparin in Patients Hospitalized for COVID-19.

Autorzy: Ewan C. Goligher, Patrick R. Lawler, Thomas P. Jensen, et al
Opublikowane w: JAMA, 2023
Wydawca: JAMA Network
DOI: 10.1001/jama.2023.3651

Monitoring key epidemiological parameters of SARS-CoV-2 transmission

Autorzy: Kraemer MUG, Pybus OG, Fraser C, Cauchemez S, Rambaut A, Cowling BJ
Opublikowane w: Nature Medicine, 2021
Wydawca: Springer Nature
DOI: 10.1038/s41591-021-01545-w

Modelling COVID-19 in school settings to evaluate prevention and control protocols

Autorzy: Colosi et al.
Opublikowane w: Anaesthesia Critical Care & Pain Medicine, 2022
Wydawca: Science Direct
DOI: 10.1016/j.accpm.2022.101047

Monitoring the proportion of the population infected by SARS-CoV-2 using age-stratified hospitalization and serological data: a modelling study

Autorzy: Hoze N, Paireau J, Lapidus N, Tran Kiem C, Salje H, Severi G, Touvier M, Zins M, de Lamballerie X, Lévy-Bruhl D, Carrat F, Cauchemez S
Opublikowane w: Lancet Public Health, 2021
Wydawca: Elsevier
DOI: 10.1016/s2468-2667(21)00064-5

Early assessment of diffusion and possible expansion of SARS-CoV-2 lineage 20I/501Y.V1 (B.1.1.7, variant of concern 202012/01) in France, January to March 2021

Autorzy: Gaymard A, Bosetti P, Feri A, Destras G, Enouf V, Andronico A, Burrel S, Behillil S, Sauvage C, Bal A, Morfin F, Van Der Werf S, Josset L, ANRS MIE AC43 COVID-19, French viro COVID group, Blanquart F, Coignard B, Cauchemez S, Lina B
Opublikowane w: Eurosurveillance, 2021
Wydawca: Eurosurveillance
DOI: 10.2807/1560-7917.es.2021.26.9.2100133

SARS-CoV-2 Beta variant infection elicits potent lineage-specific and cross-reactive antibodies

Autorzy: Reincke SM, Yuan M, Kornau HC, Corman VM, van Hoof S, Sánchez-Sendin E, Ramberger M, Yu W, Hua Y, Tien H, Schmidt ML, Schwarz T, Jeworowski LM, Brandl SE, Rasmussen HF, Homeyer MA, Stöffler L, Barner M, Kunkel D, Huo S, Horler J, von Wardenburg N, Kroidl I, Eser TM, Wieser A, Geldmacher C, Hoelscher M, Gänzer H, Weiss G, Schmitz D, Drosten C, Prüss H, Wilson IA, Kreye J
Opublikowane w: Science, 2022
Wydawca: AAAS
DOI: 10.1126/science.abm5835

Investigations on SARS-CoV-2 and other coronaviruses in mink farms in France at the end of the first year of COVID-19 pandemic.

Autorzy: Wasniewski M, Boué F, Richomme C, Simon-Lorière E, Van der Werf S, Donati F, Enouf V, Blanchard Y, Beven V, Leperchois E, Leterrier B, Corbet S, Le Gouil M, Monchatre-Leroy E, Picard-Meyer E.
Opublikowane w: bioRxiv, 2023
Wydawca: preprint
DOI: 10.1101/2023.02.02.526749

Long-term (180-Day) Outcomes in Critically Ill Patients With COVID-19 in the REMAP-CAP Randomized Clinical Trial

Autorzy: Writing Committee for the REMAP-CAP Investigators
Opublikowane w: JAMA, 2022
Wydawca: JAMA Network
DOI: 10.1001/jama.2022.23257

A single mRNA vaccine dose in COVID-19 patients boosts neutralizing antibodies against SARS-CoV-2 and variants of concern

Autorzy: van Gils MJ, van Willigen HDG, Wynberg E, Han AX, van der Straten K, Burger JA, Poniman M, Oomen M, Tejjani K, Bouhuijs JH, Verveen A, Lebbink R, Dijkstra M, Appelman B, Lavell AHA, Caniels TG, Bontjer I, van Vught LA, Vlaar APJ, Sikkens JJ, Bomers MK, Russell CA, Kootstra NA, Sanders RW, Prins M, de Bree GJ, de Jong MD
Opublikowane w: Cell Rep Med, 2021
Wydawca: Elsevier
DOI: 10.1016/j.xcrm.2021.100486

Impact of contact data resolution on the evaluation of interventions in mathematical models of infectious diseases

Autorzy: Contreras et al.
Opublikowane w: Journal of the Royal Society, 2022
Wydawca: Royal Society Publishing
DOI: 10.1098/rsif.2022.0164

Association between tocilizumab, sarilumab and all-cause mortality at 28 days in hospitalised patients with COVID-19: A network meta-analysis

Autorzy: Peter J. Godolphin, David J. Fisher, Lindsay R. Berry, Lennie P. G. Derde, Janet V. Diaz, Anthony C. Gordon, Elizabeth Lorenzi, John C. Marshall, Srinivas Murthy, Manu Shankar-Hari, Jonathan A. C. Sterne, Jayne F. Tierney, Claire L. Vale
Opublikowane w: Plos One, 2022
Wydawca: PLOS
DOI: 10.1371/journal.pone.0270668

Impact of January 2021 curfew measures on SARS-CoV-2 B.1.1.7 circulation in France

Autorzy: Laura Di Domenico, Chiara E Sabbatini, Giulia Pullano, Daniel Lévy-Bruhl, Vittoria Colizza
Opublikowane w: Eurosurveillance, 2021
Wydawca: Eurosurveillance
DOI: 10.2807/1560-7917.es.2021.26.15.2100272

Cross-reactive CD4+ T cells enhance SARS-CoV-2 immune responses upon infection and vaccination

Autorzy: Loyal L, Braun J, Henze L, Kruse B, Dingeldey M, Reimer U, Kern F, Schwarz T, Mangold M, Unger C, Dörfler F, Kadler S, Rosowski J, Gürcan K, Uyar-Aydin Z, Frentsch M, Kurth F, Schnatbaum K, Eckey M, Hippenstiel S, Hocke A, Müller MA, Sawitzki B, Miltenyi S, Paul F, Mall MA, Wenschuh H, Voigt S, Drosten C, Lauster R, Lachman N, Sander LE, Corman VM, Röhmel J, Meyer-Arndt L, Thiel A, Giesecke-Th
Opublikowane w: Science, 2021
Wydawca: AAAS
DOI: 10.1126/science.abh1823

Considerable escape of SARS-CoV-2 Omicron to antibody neutralization.

Autorzy: Planas D, Saunders N, Maes P, Guivel-Benhassine F, Planchais C, Buchrieser J, Bolland WH, Porrot F, Staropoli I, Lemoine F, Péré H, Veyer D, Puech J, Rodary J, Baele G, Dellicour S, Raymenants J, Gorissen S, Geenen C, Vanmechelen B, Wawina-Bokalanga T, Martí-Carreras J, Cuypers L, Sève A, Hocqueloux L, Prazuck T, Rey FA, Simon-Loriere E, Bruel T, Mouquet H, André E, Schwartz O.
Opublikowane w: Nature, 2022
Wydawca: nature
DOI: 10.1038/s41586-021-04389-z

Projecting the COVID-19 epidemic risk in France for the summer 2021

Autorzy: Mattia Mazzoli, Eugenio Valdano, Vittoria Colizza
Opublikowane w: Journal of travel medicine, 2021
Wydawca: Oxford Academic
DOI: 10.1093/jtm/taab129

Evolution of outcomes for patients hospitalised during the first 9 months of the SARS-CoV-2 pandemic in France: A retrospective national surveillance data analysis

Autorzy: Lefrancq N, Paireau J, Hozé N, Courtejoie N, Yazdanpanah Y, Bouadma L, Boëlle PY, Chereau F, Salje H, Cauchemez S
Opublikowane w: The Lancet Regional Health - Europe, 2021
Wydawca: Elsevier
DOI: 10.1016/j.lanepe.2021.100087

Outbreak of SARS-CoV-2 B.1.1.7 Lineage after Vaccination in Long-Term Care Facility, Germany, February-March 2021

Autorzy: Tober-Lau P, Schwarz T, Hillus D, Spieckermann J, Helbig ET, Lippert LJ, Thibeault C, Koch W, Bergfeld L, Niemeyer D, Mühlemann B, Conrad C, Kasper S, Münn F, Kunitz F, Jones TC, Suttorp N, Drosten C, Sander LE, Kurth F, Corman VM
Opublikowane w: Emerg Infect Dis, 2021
Wydawca: CDC
DOI: 10.3201/eid2708.210887

Ten months of temporal variation in the clinical journey of hospitalised patients with COVID-19: An observational cohort

Autorzy: ISARIC Clinical Characterisation Group et al
Opublikowane w: eLife, 2021
Wydawca: eLife
DOI: 10.7554/elife.70970

SARS-CoV-2 transmission across age groups in France and implications for control

Autorzy: Tran Kiem C, Bosetti P, Paireau J, Crepey P, Salje H, Lefrancq N, Fontanet A, Benamouzig D, Boelle PY, Desenclos JC, Opatowski L, Cauchemez S
Opublikowane w: Nature Communications, 2021
Wydawca: Springer Nature
DOI: 10.1038/s41467-021-27163-1

Screening and vaccination against COVID-19 to minimise school closure: a modelling study

Autorzy: Colosi et al
Opublikowane w: The Lancet Infectious Diseases, 2022
Wydawca: Science Direct
DOI: 10.1016/s1473-3099(22)00138-4

X-linked recessive TLR7 deficiency in ~1% of men under 60 years old with life-threatening COVID-19

Autorzy: T. Asano et al
Opublikowane w: Science Immunology, 2021
Wydawca: AAAS
DOI: 10.1126/sciimmunol.abl4348

The experiences of patients ill with COVID-19-like symptoms and the role of testing for SARS-CoV-2 in supporting them: A qualitative study in eight European countries during the first wave of the pandemic

Autorzy: Hoste ME, Wanat M, Gobat N, et al.
Opublikowane w: European Journal of General Practice, 2023
Wydawca: Taylor and Francis
DOI: 10.1080/13814788.2023.2212904

Drivers and impact of the early silent invasion of SARS-CoV-2 Alpha

Autorzy: Faucher et al.
Opublikowane w: 2023
Wydawca: MedrXiv
DOI: 10.1101/2023.08.21.23293488

High incidence of sotrovimab resistance and viral persistence after treatment of immunocompromised patients infected with the SARS-CoV-2 Omicron variant

Autorzy: Huygens et al
Opublikowane w: Clinical Infectious Diseases, 2022
Wydawca: Oxford Academic
DOI: 10.1093/cid/ciac601

Effect of Angiotensin-Converting Enzyme Inhibitor and Angiotensin Receptor Blocker Initiation on Organ Support-Free Days in Patients Hospitalized With COVID-19: A Randomized Clinical Trial.

Autorzy: Writing Committee for the REMAP-CAP Investigators
Opublikowane w: JAMA, 2023
Wydawca: JAMA Network
DOI: 10.1001/jama.2023.4480

Delayed Antibody and T-Cell Response to BNT162b2 Vaccination in the Elderly, Germany

Autorzy: Schwarz T, Tober-Lau P, Hillus D, Helbig ET, Lippert LJ, Thibeault C, Koch W, Landgraf I, Michel J, Bergfeld L, Niemeyer D, Mühlemann B, Conrad C, Dang-Heine C, Kasper S, Münn F, Kappert K, Nitsche A, Tauber R, Schmidt S, Kopankiewicz P, Bias H, Seybold J, von Kalle C, Jones TC, Suttorp N, Drosten C, Sander LE, Corman VM, Kurth F
Opublikowane w: Emerg Infect Dis, 2021
Wydawca: CDC
DOI: 10.3201/eid2708.211145

The experience of European hospital-based health care workers on following infection prevention and control procedures and their well-being during the first wave of the COVID-19 pandemic

Autorzy: Denise van Hout, Paul Hutchinson, Marta Wanat, Caitlin Pilbeam, Herman Goossens, Sibyl Anthierens, Sarah Tonkin-Crine, Nina Gobat
Opublikowane w: PLoS ONE, 2022
Wydawca: PLoS ONE
DOI: 10.1371/journal.pone.0245182

Analysis of Severe Acute Respiratory Syndrome 2 Replication in Explant Cultures of the Human Upper Respiratory Tract Reveals Broad Tissue Tropism of Wild-Type and B.1.1.7 Variant Viruses

Autorzy: Schulze, J., Mache, C., Balázs, A., Frey, D., Niemeyer, D., Olze, H., Dommerich, S., Drosten, C., Hocke, A. C., Mall, M. A., Hippenstiel, S., & Wolff, T
Opublikowane w: The Journal of infectious diseases, 2021
Wydawca: Oxford Academic
DOI: 10.1093/infdis/jiab523

The European clinical research response to optimise treatment of patients with COVID-19: lessons learned, future perspective, and recommendations

Autorzy: Goossens H, Horby P, Derde L, Bonten M
Opublikowane w: Lancet Infect Dis, 2021
Wydawca: The Lancet
DOI: 10.1016/s1473-3099(21)00705-2

Impact of mass testing during an epidemic rebound of SARS-CoV-2: a modelling study using the example of France

Autorzy: Bosetti P, Tran Kiem C, Yazdanpanah Y, Fontanet A, Lina B, Colizza V, Cauchemez S
Opublikowane w: Eurosurveillance, 2021
Wydawca: Eurosurveillance
DOI: 10.2807/1560-7917.es.2020.26.1.2001978

Conditionality of COVID-19 vaccine acceptance in European countries

Autorzy: Leonardo W. Heyerdahl, Muriel Vray, Benedetta Lana, Nastassia Tvardik, Nina Gobat, Marta Wanat, Sarah Tonkin-Crine, Sibyl Anthierens, Herman Goossens, Tamara Giles-Vernick
Opublikowane w: Vaccine, 2022
Wydawca: Elsevier
DOI: 10.1016/j.vaccine.2022.01.054

Modelling the end of a Zero-COVID strategy using nirmatrelvir/ritonavir, vaccination and NPIs in Wallis and Futuna

Autorzy: Brault et al
Opublikowane w: The Lancet Regional Health, 2023
Wydawca: Elsevier
DOI: 10.1016/j.lanwpc.2022.100634

An early warning system for emerging SARS-CoV-2 variants

Autorzy: Subissi L, von Gottberg A, Thukral L, Worp N, Oude Munnink BB, Rathore S, Abu-Raddad LJ, Aguilera X, Alm E, Archer BN, Attar Cohen H, Barakat A, Barclay WS, Bhiman JN, Caly L, Chand M, Chen M, Cullinane A, de Oliveira T, Drosten C, Druce J, Effler P, El Masry I, Faye A, Gaseitsiwe S, Ghedin E, Grant R, Haagmans BL, Herring BL, Iyer SS, Kassamali Z, Kakkar M, Kondor RJ, Leite JA, Leo YS, Leung GM,
Opublikowane w: Nature Medicine, 2022
Wydawca: Nature
DOI: 10.1038/s41591-022-01836-w

Fusogenicity and neutralization sensitivity of the SARS-CoV-2 Delta sublineage AY.4.2.

Autorzy: Saunders N, Planas D, Bolland WH, Rodriguez C, Fourati S, Buchrieser J, Planchais C, Prot M, Staropoli I, Guivel-Benhassine F, Porrot F, Veyer D, Péré H, Robillard N, Saliba M, Baidaliuk A, Seve A, Hocqueloux L, Prazuck T, Rey FA, Mouquet H, Simon-Lorière E, Bruel T, Pawlotsky JM, Schwartz O.
Opublikowane w: 2022
Wydawca: Science Direct
DOI: 10.1016/j.ebiom.2022.103934

Seasonal coronavirus-specific B cells with limited SARS-CoV-2 cross-reactivity dominate the IgG response in severe COVID-19

Autorzy: Aguilar-Bretones M, Westerhuis BM, Raadsen MP, de Bruin E, Chandler FD, Okba NM, Haagmans BL, Langerak T, Endeman H, van den Akker JP, Gommers DA, van Gorp EC, GeurtsvanKessel CH, de Vries RD, Fouchier RA, Rockx BH, Koopmans MP, van Nierop GP
Opublikowane w: The Journal of Clinical Investigation, 2021
Wydawca: ASCI
DOI: 10.1172/jci150613

Continuation of therapeutic dose heparin for critically ill patients with COVID-19.

Autorzy: Charlotte A. Bradbury, Patrick R. Lawler, Bryan J. McVerry & Ryan Zarychanski on behalf of the REMAP-C. A. P. Investigators
Opublikowane w: Intensive care medicine, 2023
Wydawca: Springer
DOI: 10.1007/s00134-023-07095-8

Potent human broadly SARS-CoV-2-neutralizing IgA and IgG antibodies effective against Omicron BA.1 and BA.2.

Autorzy: Planchais C, Fernández I, Bruel T, de Melo GD, Prot M, Beretta M, Guardado-Calvo P, Dufloo J, Molinos-Albert LM, Backovic M, Chiaravalli J, Giraud E, Vesin B, Conquet L, Grzelak L, Planas D, Staropoli I, Guivel-Benhassine F, Hieu T, Boullé M, Cervantes-Gonzalez M, Ungeheuer MN, Charneau P, van der Werf S, Agou F; French COVID Cohort Study Group; CORSER Study Group; Dimitrov JD, Simon-Lorière E,
Opublikowane w: Journal of Experimental Medicine, 2022
Wydawca: Rockefeller University Press
DOI: 10.1084/jem.20220638

Minimising school disruption under high incidence conditions due to the Omicron variant in France, Switzerland, Italy, in January 2022.

Autorzy: Colosi et. al.
Opublikowane w: Eurosurveillance, 2022
Wydawca: Eurosurveillance
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A synthetic nanobody targeting RBD protects hamsters from SARS-CoV-2 infection

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Interferon antagonism by SARS-CoV-2: a functional study using reverse genetics

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Performance of the FREND™ COVID-19 IgG/IgM Duo point-of-care test for SARS-CoV-2 antibody detection

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Face coverings for covid-19: from medical intervention to social practice

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Model-based evaluation of school- and non-school-related measures to control the COVID-19 pandemic

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Comparison of seven commercial SARS-CoV-2 rapid point-of-care antigen tests: a single-centre laboratory evaluation study

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Transmission of SARS-CoV-2 on mink farms between humans and mink and back to humans

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Comparison of commercial realtime reverse transcription PCR assays for the detection of SARS-CoV-2

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Tracing and analysis of 288 early SARS-CoV-2 infections outside China: A modeling study

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