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The RapiD and SecuRe AI enhAnced DiaGnosis, Precision Medicine and Patient EmpOwerment Centered Decision Support System for Coronavirus PaNdemics

Rezultaty

Validated set of business models

A report on the business model development process the decision to move forward with a set of business models to maintain the consortium and the preferred set of business models

Report on dockerization of RadiomiX

A document scoping and specifying the containerization of the solution

Report on ethical approval and informed consent for the secondary use of data from the Remdesivir clinical trial

Report on ethical approval and informed consent for the secondary use of data from the Remdesivir clinical tria

Sustainability plan

A collaboratively developed plan that includes an overall business plan and plans for the maintenanceexploitation of individual assets

RRI Charter

A 2-3 page charter based on the 6 RRI principles: 1) public engagement; 2) gender equality; 3) science education; 4) open access; 5) ethics; 6) governance.

Patient decision aid App submission

Patient decision aid App submission file for approval to the EMEA FDA authorities

Report on different stakeholder perspectives

A report based upon an interactive role playing session where different stakeholders gain insights to other perspectives with a focus on topics around triage resource allocation and precision medicine

Guide to fast track AI enhanced clinical studies for viral pandemics

A set of best practices and process for delivering fast track clinical studies to accelerate innovation for the management of viral pandemics

Report on status of posting bronchoalveolar lavage and aerosol results

A report on status of posting results for the fast track clinical trial

Report on virtual meeting with the other SARS-CoV2 projects

Report on virtual meeting with the other SARS-CoV2 projects funded under the H2020-JTI-IMI2-2020-21-single-stage call to identify synergies and areas for collaboration

Project Charter

A document that will explain the policies and procedures within the project as well as communication channels and expectations.

Initial knowledge graph based upon existing knowledge

A knowledge graph produced by systematic review of existing knowledge and the landscape of new therapeutic development that can be used to support decision making and the explainability of the analysis.

Clinical nomograms

A set of graphical calculation tools that will allow for risk assessment and clinical decision making. These will form a rapid output that can be put to use in the short term and help build up knowledge and a stakeholder community to support the development of an electronic decision support system.

Knowledge base

A database of risks, issues, opportunities and intellectual property rights (IPR) scans. Risks and issues will include the dialogue that took place in the Project Integration Team and their mitigation or resolution. Opportunities will include a description and an outline of the initial decision to pursue an opportunity and an outline of a plan.

Citizen and patient stakeholder advisory group

A group that represents the patient stakeholder perspective and that will be integrated into the working groups of the consortium assuring that the patient perspective and patient empowerment remains central to the approach of this consortium.

Dissemination materials to promote in the community

Messaging web page and articles

Dissemination and communication plan

The dissemination and communications plan outlined in section 22 expanding to include specifics of the dissemination campaigns

Publication policy

A policy that defines the process of publication and the procedures for deciding authorship

Initial dissemination materials

A set of dissemination materials for use to develop the website slide presentations etc

Data management plan

A data management plan that defines the different data types the plans for making data FAIR and for protecting privacy This document will be maintained and updated throughout the project

Publikacje

Development and Validation of an Automated Radiomic CT Signature for Detecting COVID-19

Autorzy: Julien Guiot, Akshayaa Vaidyanathan, Louis Deprez, Fadila Zerka, Denis Danthine, Anne-Noëlle Frix, Marie Thys, Monique Henket, Gregory Canivet, Stephane Mathieu, Evanthia Eftaxia, Philippe Lambin, Nathan Tsoutzidis, Benjamin Miraglio, Sean Walsh, Michel Moutschen, Renaud Louis, Paul Meunier, Wim Vos, Ralph T. H. Leijenaar, Pierre Lovinfosse
Opublikowane w: Diagnostics, Numer 11/1, 2021, Strona(/y) 41, ISSN 2075-4418
Wydawca: MDPI
DOI: 10.3390/diagnostics11010041

An externally validated fully automated deep learning algorithm to classify COVID-19 and other pneumonias on chest CT

Autorzy: Akshayaa Vaidyanathan, Julien Guiot, Fadila Zerka, Flore Belmans, Ingrid Van Peufflik, Louis Deprez, Denis Danthine, Gregory Canivet, Philippe Lambin, Sean Walsh, Mariaelena Occchipinti, Paul Meunier, Wim Vos, Pierre Lovinfosse, Ralph T.H. Leijenaar
Opublikowane w: ERJ Open Research, Numer 8(2), 2022, Strona(/y) 579-2021, ISSN 2312-0541
Wydawca: ERJ Open Research
DOI: 10.1183/23120541.00579-2021

Privacy preserving distributed learning classifiers – Sequential learning with small sets of data

Autorzy: Fadila Zerka, Visara Urovi, Fabio Bottari, Ralph T.H. Leijenaar, Sean Walsh, Hanif Gabrani-Juma, Martin Gueuning, Akshayaa Vaidyanathan, Wim Vos, Mariaelena Occhipinti, Henry C. Woodruff, Michel Dumontier, Philippe Lambin
Opublikowane w: Computers in Biology and Medicine, Numer 136, 2021, Strona(/y) 104716, ISSN 0010-4825
Wydawca: Pergamon Press Ltd.
DOI: 10.1016/j.compbiomed.2021.104716

Doubts and concerns about COVID-19 uncertainties on imaging data, clinical score, and outcomes

Autorzy: Cosimo Nardi, Andrea Magnini, Linda Calistri Edoardo Cavigli , Anna Julie Peired, Vieri Rastrelli , Edoardo Carlesi , Giulia Zantonelli , Olga Smorchkova, Lorenzo Cinci , Martina Orlandi , Nicholas Landini , Edoardo Berillo , Chiara Lorini , Jessica Mencarini , Maria Grazia Colao , Leonardo Gori , Valentina Luzzi , Chiara Lazzeri , Elisa Cipriani , Manuela Bonizzoli , Filippo Pieralli, Carlo Nozz
Opublikowane w: BMC Pulm Med, Numer Nov 25;23(1):472, 2023, ISSN 1471-2466
Wydawca: BioMed Central
DOI: 10.1186/s12890-023-02763-3

Automatized lung disease quantification in patients with COVID-19 as a predictive tool to assess hospitalization severity

Autorzy: Julien Guiot, Nathalie Maes, Marie Winandy, Monique Henket, Benoit Ernst, Marie Thys, Anne-Noelle Frix, Philippe Morimont, Anne-Françoise Rousseau, Perrine Canivet, Renaud Louis, Benoît Misset, Paul Meunier, Jean-Paul Charbonnier and Bernard Lambermont
Opublikowane w: Frontiers in Medicine, Numer Vol 9, 2022, ISSN 2296-858X
Wydawca: Frontiers Media S.A.
DOI: 10.3389/fmed.2022.930055

Can predicting COVID-19 mortality in a European cohort using only demographic and comorbidity data surpass age-based prediction: An externally validated study

Autorzy: Avishek Chatterjee, Guangyao Wu, Sergey Primakov, Cary Oberije, Henry Woodruff, Pieter Kubben, Ronald Henry, Marcel J. H. Aries, Martijn Beudel, Peter G. Noordzij, Tom Dormans, Niels C. Gritters van den Oever, Joop P. van den Bergh, Caroline E. Wyers, Suat Simsek, Renée Douma, Auke C. Reidinga, Martijn D. de Kruif, Julien Guiot, Anne-Noelle Frix, Renaud Louis, Michel Moutschen, Pierre Lovinfosse,
Opublikowane w: PLOS ONE, Numer 16/4, 2021, Strona(/y) e0249920, ISSN 1932-6203
Wydawca: Public Library of Science
DOI: 10.1371/journal.pone.0249920

The SARS-CoV-2 viral load in COVID-19 patients is lower on face mask filters than on nasopharyngeal swabs

Autorzy: Agnieszka Smolinska, David S. Jessop, Kirk L. Pappan, Alexandra De Saedeleer, Amerjit Kang, Alexandra L. Martin, Max Allsworth, Charlotte Tyson, Martine P. Bos, Matt Clancy, Mike Morel, Tony Cooke, Tom Dymond, Claire Harris, Jacqui Galloway, Paul Bresser, Nynke Dijkstra, Viresh Jagesar, Paul H. M. Savelkoul, Erik V. H. Beuken, Wesley H. V. Nix, Renaud Louis, Muriel Delvaux, Doriane Calmes, Benoit
Opublikowane w: Scientific Reports, Numer 11/1, 2021, ISSN 2045-2322
Wydawca: Nature Publishing Group
DOI: 10.1038/s41598-021-92665-3

Accuracy of the multidisciplinary diagnosis of COVID-19 in patients with negative nasopharyngeal swabs RT-PCR, evaluated using BAL as diagnostic gold standard

Autorzy: Sara Tomassetti, Valentina Luzzi, Giulia Biadene, Guja Bernacchi, Leonardo Gori, Sonia Bambina, Marco De Martino, Edoardo Cavigli, Diletta Cozzi, Vittorio Miele, Gianmaria Rossolini, Simona Pollini, Cosimo Nardi, Anna Peired, Alessandro Morettini, Carlo Nozzoli, Adriana Poggesi, Lorenzo Menicacci, Valentina Scotti, Giogia Falchetti, Elias Romano, Ombretta Para, Lorenzo Caruso, Federico Lavorini
Opublikowane w: European Respiratory Journal, Numer 58, 2021, ISSN 0903-1936
Wydawca: European Respiratory Society
DOI: 10.1183/13993003.congress-2021.pa840

Limitations of Only Reporting the Odds Ratio in the Age of Precision Medicine: A Deterministic Simulation Study

Autorzy: Avishek Chatterjee, Henry Woodruff, Guangyao Wu, Philippe Lambin
Opublikowane w: Frontiers in Medicine, Numer 8, 2021, ISSN 2296-858X
Wydawca: Frontiers in Medicine
DOI: 10.3389/fmed.2021.640854

The Role of Imaging in the Detection of Non-COVID-19 Pathologies during the Massive Screening of the First Pandemic Wave

Autorzy: Perrine Canivet, Colin Desir, Marie Thys, Monique Henket, Anne-Noëlle Frix, Benoit Ernst, Sean Walsh, Mariaelena Occhipinti, Wim Vos, Nathalie Maes, Jean Luc Canivet, Renaud Louis, Paul Meunier and Julien Guiot
Opublikowane w: Diagnostics, Numer 12(7), 2022, ISSN 2075-4418
Wydawca: MDPI
DOI: 10.3390/diagnostics12071567

Knowledge Graphs for COVID-19: An Exploratory Review of the Current Landscape

Autorzy: Avishek Chatterjee, Cosimo Nardi, Cary Oberije, Philippe Lambin
Opublikowane w: Journal of Personalized Medicine, Numer 11/4, 2021, Strona(/y) 300, ISSN 2075-4426
Wydawca: MDPI
DOI: 10.3390/jpm11040300

Utility of bronchoalveolar lavage for COVID-19: a perspective from the Dragon consortium

Autorzy: Sara Tomassetti, Luca Ciani, Valentina Luzzi, Leonardo Gori, Marco Trigiani, Leonardo Giuntoli, Federico Lavorini, Venerino Poletti, Claudia Ravaglia, Alfons Torrego, Fabien Maldonado, Robert Lentz, Francesco Annunziato, Laura Maggi, Gian Maria Rossolini, Simona Pollini, Ombretta Para , Greta Ciurleo, Alessandro Casini, Laura Rasero, Alessandro Bartoloni, Michele Spinicci, Mohammed Munavvar, Stefa
Opublikowane w: Front Med (Lausanne), Numer 024 Feb 2:11:1259570, 2024, ISSN 2296-858X
Wydawca: Frontiers
DOI: 10.3389/fmed.2024.1259570

Deep learning architecture for the classification of COVID-19 and others pneumonias sources on lung CT imaging

Autorzy: Akshayaa Vaidyanathan, Julien Guiot, Fadila Zerka, Louis Deprez, Denis Danthine, Fabio Bottari, Gregory Canivet, Philippe Lambin, Sean Walsh, Mariaelena Occhipinti, Paul Meunier, Wim Vos, Pierre Lovinfosse, Ralph T.H. Leijenaar
Opublikowane w: European Respiratory Journal, 2021, ISSN 0903-1936
Wydawca: European Respiratory Society
DOI: 10.1183/13993003.congress-2021.oa1561

Prediction of outcome in COVID-19 patients based on clinical and radiomics chest CT data

Autorzy: Julien Guiot, Akshayaa Vaidyanathan, Fadila Zerka, Louis Deprez, Denis Danthine, Anne-Noëlle Frix, Fabio Bottari, Monique Henket, Stephane Mathieu, Philippe Lambin, Sean Walsh, Mariaelena Occhipinti, Benoit Misset, Louis Renard, Paul Meunier, Wim Vos, Ralph T.H. Leijenaar, Pierre Lovinfosse,
Opublikowane w: European Respiratory Journal, 2021, ISSN 0903-1936
Wydawca: European Respiratory Society
DOI: 10.1183/13993003.congress-2021.pa361

Improving and Externally Validating Mortality Prediction Models for COVID-19 Using Publicly Available Data

Autorzy: Avishek Chatterjee, Guus Wilmink, Henry Woodruff and Philippe Lambin
Opublikowane w: BioMed, 2022, Strona(/y) 13-26, ISSN 2078-2489
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/biomed2010002

Data harmonisation for information fusion in digital healthcare: A state-of-the-art systematic review, meta-analysis and future research directions

Autorzy: Yang Nan, Javier Del Ser, Simon Walsh, Carola Schonlieb, Michael Roberts, Ian Selby, Kit Howard, John Owen, Jon Neville, Julien Guiot, Benoit Ernst, Ana Pastor, Angel Alberich-Bayarri, Marion I. Menzel, Sean Walsh, Wim Vos, Nina Flerin, Jean-Paul Charbonnier, Eva van Rikxoort, Avishek Chatterjee, Henry Woodruff, Philippe Lambin, Leonor Cerda-Alberich, Luis Martí-Bonmatí, Francisco Herrera, Guang
Opublikowane w: Information Fusion, Numer 82, 2022, Strona(/y) 99-122, ISSN 1566-2535
Wydawca: Elsevier BV
DOI: 10.1016/j.inffus.2022.01.001

Covid19Risk.ai: An open source repository and online calculator of prediction models for early diagnosis and prognosis of Covid-19

Autorzy: View ORCID ProfileIva Halilaj, Avishek Chatterjee, Yvonka van Wijk, Guangyao Wu, Brice van Eeckhout, Cary Oberije, Philippe Lambin
Opublikowane w: bioRxiv, 2021
Wydawca: Cold spring harbor laboratory
DOI: 10.1101/2021.01.05.425384

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