ENDING COVID 19 VARIANTS OF CONCERN THROUGH COHORT STUDIES: END-VOC

Projektinformationen

END-VOC

ID Finanzhilfevereinbarung: 101046314

DOI

10.3030/101046314

Projekt abgeschlossen

EK-Unterschriftsdatum 17 August 2022

Startdatum 1 Mai 2022

Enddatum 30 April 2025

Finanziert unter

• Health

Gesamtkosten

€ 10 496 136,51

EU-Beitrag

€ 10 496 136,50

Koordiniert durch

UNIVERSITY COLLEGE LONDON
United Kingdom

CORDIS bietet Links zu öffentlichen Ergebnissen und Veröffentlichungen von HORIZONT-Projekten.

Links zu Ergebnissen und Veröffentlichungen von RP7-Projekten sowie Links zu einigen Typen spezifischer Ergebnisse wie Datensätzen und Software werden dynamisch von OpenAIRE abgerufen.

Leistungen

Documents, reports (21)

Travel surveillance network established

Integrated travel surveillance network established with new VOC reporting mechanism

Mutation prediction pipeline

Application of mutation prediction pipeline to assess transmissibility of all SARSCoV2 lineages including VOCs regularly and close to real time

Website
Mathematical transmission dynamic model update

Updated version of the mathematical model to include multiple variants applicability to all partner Cohorts

Data warehouse

Data warehouse and acquisition platform

Risk factors for long COVID

Initial analysis of risk factors for Long COVID by VOC

Data Management Plan (Interim version)

Updated data management plan

Biospecimen Handbook

Handbook for biospecimen collections

In vitro SARS-CoV-2 model of various VOCs for antiviral screening studies

Development of in vitro SARS-CoV-2 model of various VOCs for antiviral screening studies

DEC plan
Mechanism of VOC transmission using genetic models

Study on the mechanisms of transmission in VOCs and VOIs based on genetic models

Protocols/questionnaires

Common protocols with questionnaires and procedures for prospective data harmonization and retrospective data reconciliation

Data Management Plan (draft version)

A Data Management Plan DMP following the HE guidelines will address the relevant aspects of making data FAIR including what data the project will generate whether and how it will be made accessible for verification and reuse and how it will be curated and preserved The DMP will include details of the security technical and organisational measures to be taken in the context of the transfer of data from nonEU countries to prevent unauthorised access to personal data and safeguard the rights and freedoms of the data subjectsresearch participants

Data standards/harmonisation

Establish data standardisation and harmonisation processes

Sequencing pipeline optimisation completed

Optimise sequencing pipeline and provide support to cohorts

Infographics to disseminate key results

Infographics with key messages or results will be produced throughout the project

Risk factor for COVID and clinical outcome analysis protocol

Established protocol for analysis of risk factor and clinical outcome data

Central Code Repository

Central code repository, software documentation and versioning system

Best practice guidelines for governance structures and processes

Document outlining best practice for governance structures and processes to be used by the consortium

Impact Monitoring Framework

A framework to allow monitoring of impact

Cohort network and inclusion

Establish network and inclusion of population and clinical cohorts

Veröffentlichungen

Peer reviewed articles (4)

Genomic screening of 16 UK native bat species through conservationist networks uncovers coronaviruses with zoonotic potential

Autoren: Tan, C.C.S., Trew, J., Peacock, T.P. et al.
Veröffentlicht in: Nature Communications, Ausgabe 14, 2023, ISSN 2041-1723
Herausgeber: Nature Publishing Group
DOI: 10.1038/s41467-023-38717-w

The role of immune suppression in COVID-19 hospitalization: clinical and epidemiological trends over three years of SARS-CoV-2 epidemic

Autoren: Canuti M, Monti MC, Bobbio C, Muscatello A, Muheberimana T, Baldi SL, Blasi F, Canetta C, Costantino G, Nobili A, Peyvandi F, Tettamanti M, Villa S, Aliberti S, Raviglione MC, Gori A, Bandera A and COVID-19 Network Study Group
Veröffentlicht in: Frontiers in Medicine, Ausgabe Vol. 10, 2023, ISSN 2296-858X
Herausgeber: Frontiers Media
DOI: 10.3389/fmed.2023.1260950

Cohort Profile: Virus Watch—understanding community incidence, symptom profiles and transmission of COVID-19 in relation to population movement and behaviour

Autoren: T. Byrne, J. Kovar, S. Beale, I. Braithwaite, E. Fragaszy, W. L. E. Fong, C. Geismar, S. Hoskins, A. M D Navaratnam, V. Nguyen, P. Patel, M. Shrotri, A. Yavlinsky, P. Hardelid, L. Wijlaars, E. Nastouli, M. Spyer, A. Aryee, I. Cox, ..., R. W Aldridge
Veröffentlicht in: International Journal of Epidemiology, Ausgabe Vol.10, Ausgabe 5, 2023, ISSN 1464-3685
Herausgeber: Oxford University Press
DOI: 10.1093/ije/dyad087

Exploring post-SEPSIS and post-COVID-19 syndromes: crossovers from pathophysiology to therapeutic approach

Autoren: Darcy Holmes, Marta Colaneri, Emanuele Palomba, Andrea Gori
Veröffentlicht in: Frontiers in Medicine, Ausgabe 10, 2024, ISSN 2296-858X
Herausgeber: Frontiers Media
DOI: 10.3389/fmed.2023.1280951