Descrizione del progetto
Ridurre l’inquinamento migliorando i biosistemi
La decomposizione degli agenti inquinanti richiede biosistemi costituiti da una combinazione di batteri, funghi e piante. Il progetto BIOSYSMO, finanziato dall’UE, svilupperà un metodo assistito a livello informatico per progettare sistemi di tal genere che sfrutti la diversità microbica naturale. Il progetto effettuerà lo screening di campioni provenienti da siti e luoghi inquinati al fine di individuare i microrganismi naturali già presenti che sono in grado di metabolizzare gli inquinanti bersaglio. Questa ricerca verrà quindi estesa a microrganismi identificati in precedenza mediante l’applicazione di strumenti per l’estrazione di dati ai dati genomici e metagenomici disponibili all’interno di archivi pubblici. I batteri, le piante e i funghi selezionati saranno successivamente combinati in biosistemi sinergici potenziati. I biosistemi realizzati saranno applicati al suolo, ai sedimenti e all’acqua attraverso l’adozione di vari approcci: fitorisanamento, biopile, reattori bioelettrochimici e bioaumento.
Obiettivo
BIOSYSMO is a 48-month action that will develop a computationally-assisted framework for designing and optimizing synergistic biosystems combining the required pathways and traits to achieve the most efficient degradation and sequestration of pollutant mixtures. These biosystems will comprise combinations of bacteria, fungi and plants containing the natural or engineered pathways required for pollutants degradation and identified based on a computationally-assisted analysis. BIOSYSMO will take advantage of the high natural microbial diversity by screening samples from polluted sites and locations affected by diffuse pollution to identify natural microorganisms already present and able to metabolize the target pollutants. The search will be expanded to microorganisms previously identified and characterized by applying data mining tools to genomic and metagenomic data available in public repositories.
The construction and optimization of synergistic biosystems will combine approaches based on 1) enhancing plant-microbe (bacteria, fungi) interactions to achieving combinations with improved pollutant uptake and/or degradation; 2) engineering bacteria, for improved degradation and bioaugmentation, and plants (poplar tree), for improved microbial colonization and pollutant uptake; 3) constructing artificial micro-structured consortia into aggregates and biofilms, containing all the required pathways for pollutant removal; and 4) applying bioelectrochemical systems (BES) as stand-alone or in hybrid systems. The different key players will be identified and combined to formulate innovative biosystems with the assistance of genome-scale metabolic (GEM) models for elucidating and simulating the key metabolic pathways. The constructed biosystems will be applied in conventional (phytoremediation, biopile, bioaugmentation) and innovative (BES, hybrid BES-phytoremediation) bioremediation approaches optimized for the treatment of mixtures of pollutants in soil, sediments and water.
Campo scientifico
- natural sciencesbiological sciencesmicrobiologybacteriology
- natural scienceschemical scienceselectrochemistrybioelectrochemistry
- natural sciencesbiological sciencesmicrobiologymycology
- natural sciencescomputer and information sciencesdata sciencedata mining
- natural sciencesearth and related environmental sciencesenvironmental sciencespollution
Parole chiave
Programma(i)
Meccanismo di finanziamento
HORIZON-RIA - HORIZON Research and Innovation ActionsCoordinatore
41300 LA RINCONADA SEVILLA
Spagna