Personalised blueprint intestinal health

Projektinformationen

miGut-Health

ID Finanzhilfevereinbarung: 101095470

DOI

10.3030/101095470

EK-Unterschriftsdatum 11 November 2022

Startdatum 1 Januar 2023

Enddatum 31 Dezember 2026

Finanziert unter

• Health

Gesamtkosten

€ 7 131 243,75

EU-Beitrag

€ 7 126 243,75

Koordiniert durch

UNIVERSITATSKLINIKUM SCHLESWIG-HOLSTEIN
Germany

CORDIS bietet Links zu öffentlichen Ergebnissen und Veröffentlichungen von HORIZONT-Projekten.

Links zu Ergebnissen und Veröffentlichungen von RP7-Projekten sowie Links zu einigen Typen spezifischer Ergebnisse wie Datensätzen und Software werden dynamisch von OpenAIRE abgerufen.

Leistungen

Documents, reports (4)

Predictive lifestyle factors

Report on predictive lifestyle factors that correlate with disease activity based on data collected with the IBD Coach eHealth tool.

Study initiation package

Finalization of study materials (e.g. dietary advisory material for study participants, CRFs), study protocol and study registration, preparation of patient recruitment.

“Personas” describing health engagement risk profiles

The “Personas” will consist in the description of prototypical profiles of health engagement risk on the basis of the empirical analysis conducted through the online survey. The Personas will be aimed at depicting different psychosocial risk factors profiles and their real-world impact on health and diet-related engagement behaviours and ultimately suggest priorities of educational actions in order to prevent risks.

Midterm recruitment report

Midterm recruitment will be reported, when approximately half of the study population is recruited including an overview of the number of screened and recruited participants at UKE, any problems in recruitment and, if applicable, a detailed description of implemented and planned measures to compensate for any incurred delays.

Websites, patent fillings, videos etc. (2)

Public project website

The website will inform the public about the project’s aims, updates and results. The website will be continuously updated throughout the project’s lifetime.

Audio-visual material 1

A set of different audio-visual material including one larger production - Part 1.

Other (1)

Extension of AI-assisted MyFoodRepo app for diet tracking

The MyFoodRepo app will be locally adapted in order to be usable in countries where project studies will be performed.

Veröffentlichungen

Peer reviewed articles (12)

Mucosal host-microbe interactions associate with clinical phenotypes in inflammatory bowel disease

Autoren: Shixian Hu, Arno R. Bourgonje, Ranko Gacesa, Bernadien H. Jansen, Johannes R. Björk, Amber Bangma, Iwan J. Hidding, Hendrik M. van Dullemen, Marijn C. Visschedijk, Klaas Nico Faber, Gerard Dijkstra, Hermie J. M. Harmsen, Eleonora A. M. Festen, Arnau Vich
Veröffentlicht in: Nature Communication, Ausgabe 15, 1470 (2024), 2024, ISSN 2041-1723
Herausgeber: Nature Communications
DOI: 10.1038/s41467-024-45855-2

The Role of Environmental Factors Prior to Diagnosis on the Activity and Severity of Inflammatory Bowel Diseases—Results From the Prospective Population‐Based Copenhagen Inflammatory Bowel Disease Inception Cohort

Autoren: Mohamed Attauabi, Gorm Roager Madsen, Flemming Bendtsen, Johan Burisch, Jakob Benedict Seidelin
Veröffentlicht in: United European Gastroenterology Journal, 2025, ISSN 2050-6406
Herausgeber: Wiley
DOI: 10.1002/UEG2.12737

Preclinical Protein Signatures of Crohn’s Disease and Ulcerative Colitis: A Nested Case-Control Study Within Large Population-Based Cohorts

Autoren: Olle Grännö, Daniel Bergemalm, Benita Salomon, Carl Mårten Lindqvist, Charlotte R. H. Hedin, Marie Carlson, Katharina Dannenberg, Erik Andersson, Åsa V. Keita, Maria K. Magnusson, Carl Eriksson, Vivekananda Lanka, Patrik K.E. Magnusson, Mauro D’Amato...
Veröffentlicht in: Gastroenterology, Ausgabe 6, 2024, ISSN 1528-0012
Herausgeber: Elsevier Inc.
DOI: 10.1053/j.gastro.2024.11.006

Bulk T cell repertoire sequencing (TCR-Seq) is a powerful technology for understanding inflammation-mediated diseases

Autoren: Aya K.H. Mahdy, Evgeniya Lokes, Valentina Schöpfel, Valeriia Kriukova, Olga V. Britanova, Tim A. Steiert, Andre Franke, Hesham ElAbd
Veröffentlicht in: Journal of Autoimmunity, Ausgabe 149, 2024, ISSN 0896-8411
Herausgeber: Elsevier BV
DOI: 10.1016/J.JAUT.2024.103337

Comparing Environmental Risk Factors at Diagnosis in Faroese and Danish Patients with Inflammatory Bowel Disease

Autoren: Nielsen, Kári Rubek; Modin, Frederikke Agerbo; Midjord, Jóngerð; Vang, Amanda; Berbisá, Marjun á.Fríðriksmørk; Johannesen, Herborg Líggjasardóttir; Dahlerup, Jens Frederik; Andersen, Vibeke; Neumann, Anders; Kjeldsen, Jens; Pedersen, Natalia; Langholz, Ebbe; Munkholm, Pia; Hammer, Turid; Burisch, Johan
Veröffentlicht in: Digestive Diseases and Sciences, Ausgabe 69, 2024, ISSN 1573-2568
Herausgeber: Springer Nature
DOI: 10.1007/S10620-024-08721-1

Food-Related Behavioral Patterns in Patients with Inflammatory Bowel Diseases: The Role of Food Involvement and Health Engagement

Autoren: Lorenzo Palamenghi, Dilara Usta, Salvo Leone, Gunedalina Graffigna
Veröffentlicht in: Nutrients, Ausgabe 16(8), 1185, 2024, ISSN 2072-6643
Herausgeber: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/nu16081185

Untargeted faecal metabolomics for the discovery of biomarkers and treatment targets for inflammatory bowel diseases

Autoren: Vich Vila A, Zhang J, Liu M, Faber KN, Weersma RK
Veröffentlicht in: Gut, Ausgabe 73, 2024, ISSN 1468-3288
Herausgeber: BMJ Group
DOI: 10.1136/GUTJNL-2023-329969

The Substantial Role of Sleep, Stress, and Physical Activity in Persistent High Levels of Fatigue in Patients With Inflammatory Bowel Disease: A Longitudinal Trajectory Study

Autoren: Quirine M Bredero, Joke Fleer, Denise M Blom, Arno R Bourgonje, Gerard Dijkstra, Maya J Schroevers
Veröffentlicht in: Journal of Crohn's and Colitis, Ausgabe 19, 2025, ISSN 1873-9946
Herausgeber: Oxford University Press (OUP)
DOI: 10.1093/ECCO-JCC/JJAE163

Reasons for (Not) Seeking Care for Fatigue and Care Needs Among Patients With Inflammatory Bowel Disease: A Qualitative Interview Study

Autoren: Quirine M. Bredero, Milou M. Ter Avest, Gerard Dijkstra, Joke Fleer, Maya J. Schroevers
Veröffentlicht in: Journal of Advanced Nursing, 2025, ISSN 0309-2402
Herausgeber: Wiley
DOI: 10.1111/JAN.16837

The gut microbiome in end-stage lung disease and lung transplantation

Autoren: Shuyan Zhang, J. Casper Swarte, Ranko Gacesa, Tim J. Knobbe, Daan Kremer, Bernadien H. Jansen, Martin H. de Borst, null null, Hermie J. M. Harmsen, Michiel E. Erasmus, Erik A. M. Verschuuren, Stephan J. L. Bakker, C. Tji Gan, Rinse K. Weersma, Johannes R. Björk, Coby Annema, Stephan J. L. Bakker, Stefan P. Berger, Hans Blokzijl, Frank A. J. A. Bodewes, Marieke T. de Boer, Kevin Damman, Martin H. de Borst, Arjan Diepstra, Gerard Dijkstra, Rianne M. Douwes, Caecilia S. E. Doorenbos, Michele F. Eisenga, Michiel E. Erasmus, C. Tji Gan, Eelko Hak, Bouke G. Hepkema, Frank Klont, Tim J. Knobbe, Daan Kremer, Henri G. D. Leuvenink, Willem S. Lexmond, Vincent E. de Meijer, Hubert G. M. Niesters, Gertrude J. Nieuwenhuis-Moeke, L. Joost van Pelt, Robert A. Pol, Robert J. Porte, Adelta V. Ranchor, Marion J. Siebelink, Riemer J. H. J. A. Slart, J. Casper Swarte, Daan J. Touw, Marius C. van den Heuvel, Coretta van Leer-Buter, Marco van Londen, Erik A. M. Verschuuren, Michel J. Vos, Rinse K. Weersma, Antonio W. Gomes Neto, Jan Stephan F. Sanders
Veröffentlicht in: mSystems, Ausgabe 9, 2024, ISSN 2379-5077
Herausgeber: American Society for Microbiology
DOI: 10.1128/MSYSTEMS.01312-23

Health-related quality of life is linked to the gut microbiome in kidney transplant recipients

Autoren: J. Casper Swarte, Tim J. Knobbe, Johannes R. Björk, Ranko Gacesa, Lianne M. Nieuwenhuis, Shuyan Zhang, Arnau Vich Vila, Daan Kremer, Rianne M. Douwes, Adrian Post, Evelien E. Quint, Robert A. Pol, Bernadien H. Jansen, null null, C. Annema, F. A. J. A. Bodewes, M. T. de Boer, K. Damman, A. Diepstra, G. Dijkstra, C. S. E. Doorenbos, M. F. Eisenga, M. E. Erasmus, C. T. Gan, A. W. Gomes Neto, E. Hak, B. G. Hepkema, F. Klont, H. G. D. Leuvenink, W. S. Lexmond, G. J. Nieuwenhuis-Moeke, H. G. M. Niesters, L. J. van Pelt, A. V. Ranchor, J. S. F. Sanders, M. J. Siebelink, R. J. H. J. A. Slart, D. J. Touw, M. C. van den Heuvel, C. van Leer-Buter, M. van Londen, E. A. M. Verschuuren, M. J. Vos, Martin H. de Borst, Vincent E. de Meijer, Hans Blokzijl, Stefan P. Berger, Eleonora A. M. Festen, Alexandra Zhernakova, Jingyuan Fu, Hermie J. M. Harmsen, Stephan J. L. Bakker, Rinse K. Weersma
Veröffentlicht in: Nature Communications, Ausgabe 14, 2023, ISSN 2041-1723
Herausgeber: Springer Science and Business Media LLC
DOI: 10.1038/s41467-023-43431-8

Phage-display immunoprecipitation sequencing of the antibody epitope repertoire in inflammatory bowel disease reveals distinct antibody signatures

Autoren: Arno R. Bourgonje; Sergio Andreu-Sánchez; Thomas Vogl; Shixian Hu; Arnau Vich Vila; Ranko Gacesa; Sigal Leviatan; Alexander Kurilshikov; Shelley Klompus; Iris N. Kalka; Hendrik M. van Dullemen; Adina Weinberger; Marijn C. Visschedijk; Eleonora A.M. Festen; Klaas Nico Faber; Cisca Wijmenga; Gerard Dijkstra; Eran Segal; Jingyuan Fu; Alexandra Zhernakova; Rinse K. Weersma
Veröffentlicht in: Immunity, Ausgabe Vol. 56, issue 6, 2023, ISSN 1097-4180
Herausgeber: Cell Press
DOI: 10.1016/j.immuni.2023.04.017