Personalised blueprint intestinal health

Informacje na temat projektu

miGut-Health

Identyfikator umowy o grant: 101095470

DOI

10.3030/101095470

Data podpisania przez KE 11 Listopada 2022

Data rozpoczęcia 1 Stycznia 2023

Data zakończenia 31 Grudnia 2026

Finansowanie w ramach

• Health

Koszt całkowity

€ 7 131 243,75

Wkład UE

€ 7 126 243,75

Koordynowany przez

UNIVERSITATSKLINIKUM SCHLESWIG-HOLSTEIN
Germany

CORDIS oferuje możliwość skorzystania z odnośników do publicznie dostępnych publikacji i rezultatów projektów realizowanych w ramach programów ramowych HORYZONT.

Odnośniki do rezultatów i publikacji związanych z poszczególnymi projektami 7PR, a także odnośniki do niektórych konkretnych kategorii wyników, takich jak zbiory danych i oprogramowanie, są dynamicznie pobierane z systemu OpenAIRE .

Rezultaty

Documents, reports (4)

Predictive lifestyle factors

Report on predictive lifestyle factors that correlate with disease activity based on data collected with the IBD Coach eHealth tool.

Study initiation package

Finalization of study materials (e.g. dietary advisory material for study participants, CRFs), study protocol and study registration, preparation of patient recruitment.

“Personas” describing health engagement risk profiles

The “Personas” will consist in the description of prototypical profiles of health engagement risk on the basis of the empirical analysis conducted through the online survey. The Personas will be aimed at depicting different psychosocial risk factors profiles and their real-world impact on health and diet-related engagement behaviours and ultimately suggest priorities of educational actions in order to prevent risks.

Midterm recruitment report

Midterm recruitment will be reported, when approximately half of the study population is recruited including an overview of the number of screened and recruited participants at UKE, any problems in recruitment and, if applicable, a detailed description of implemented and planned measures to compensate for any incurred delays.

Websites, patent fillings, videos etc. (2)

Public project website

The website will inform the public about the project’s aims, updates and results. The website will be continuously updated throughout the project’s lifetime.

Audio-visual material 1

A set of different audio-visual material including one larger production - Part 1.

Other (1)

Extension of AI-assisted MyFoodRepo app for diet tracking

The MyFoodRepo app will be locally adapted in order to be usable in countries where project studies will be performed.

Publikacje

Peer reviewed articles (12)

Mucosal host-microbe interactions associate with clinical phenotypes in inflammatory bowel disease

Autorzy: Shixian Hu, Arno R. Bourgonje, Ranko Gacesa, Bernadien H. Jansen, Johannes R. Björk, Amber Bangma, Iwan J. Hidding, Hendrik M. van Dullemen, Marijn C. Visschedijk, Klaas Nico Faber, Gerard Dijkstra, Hermie J. M. Harmsen, Eleonora A. M. Festen, Arnau Vich
Opublikowane w: Nature Communication, Numer 15, 1470 (2024), 2024, ISSN 2041-1723
Wydawca: Nature Communications
DOI: 10.1038/s41467-024-45855-2

The Role of Environmental Factors Prior to Diagnosis on the Activity and Severity of Inflammatory Bowel Diseases—Results From the Prospective Population‐Based Copenhagen Inflammatory Bowel Disease Inception Cohort

Autorzy: Mohamed Attauabi, Gorm Roager Madsen, Flemming Bendtsen, Johan Burisch, Jakob Benedict Seidelin
Opublikowane w: United European Gastroenterology Journal, 2025, ISSN 2050-6406
Wydawca: Wiley
DOI: 10.1002/UEG2.12737

Preclinical Protein Signatures of Crohn’s Disease and Ulcerative Colitis: A Nested Case-Control Study Within Large Population-Based Cohorts

Autorzy: Olle Grännö, Daniel Bergemalm, Benita Salomon, Carl Mårten Lindqvist, Charlotte R. H. Hedin, Marie Carlson, Katharina Dannenberg, Erik Andersson, Åsa V. Keita, Maria K. Magnusson, Carl Eriksson, Vivekananda Lanka, Patrik K.E. Magnusson, Mauro D’Amato...
Opublikowane w: Gastroenterology, Numer 6, 2024, ISSN 1528-0012
Wydawca: Elsevier Inc.
DOI: 10.1053/j.gastro.2024.11.006

Bulk T cell repertoire sequencing (TCR-Seq) is a powerful technology for understanding inflammation-mediated diseases

Autorzy: Aya K.H. Mahdy, Evgeniya Lokes, Valentina Schöpfel, Valeriia Kriukova, Olga V. Britanova, Tim A. Steiert, Andre Franke, Hesham ElAbd
Opublikowane w: Journal of Autoimmunity, Numer 149, 2024, ISSN 0896-8411
Wydawca: Elsevier BV
DOI: 10.1016/J.JAUT.2024.103337

Comparing Environmental Risk Factors at Diagnosis in Faroese and Danish Patients with Inflammatory Bowel Disease

Autorzy: Nielsen, Kári Rubek; Modin, Frederikke Agerbo; Midjord, Jóngerð; Vang, Amanda; Berbisá, Marjun á.Fríðriksmørk; Johannesen, Herborg Líggjasardóttir; Dahlerup, Jens Frederik; Andersen, Vibeke; Neumann, Anders; Kjeldsen, Jens; Pedersen, Natalia; Langholz, Ebbe; Munkholm, Pia; Hammer, Turid; Burisch, Johan
Opublikowane w: Digestive Diseases and Sciences, Numer 69, 2024, ISSN 1573-2568
Wydawca: Springer Nature
DOI: 10.1007/S10620-024-08721-1

Food-Related Behavioral Patterns in Patients with Inflammatory Bowel Diseases: The Role of Food Involvement and Health Engagement

Autorzy: Lorenzo Palamenghi, Dilara Usta, Salvo Leone, Gunedalina Graffigna
Opublikowane w: Nutrients, Numer 16(8), 1185, 2024, ISSN 2072-6643
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/nu16081185

Untargeted faecal metabolomics for the discovery of biomarkers and treatment targets for inflammatory bowel diseases

Autorzy: Vich Vila A, Zhang J, Liu M, Faber KN, Weersma RK
Opublikowane w: Gut, Numer 73, 2024, ISSN 1468-3288
Wydawca: BMJ Group
DOI: 10.1136/GUTJNL-2023-329969

The Substantial Role of Sleep, Stress, and Physical Activity in Persistent High Levels of Fatigue in Patients With Inflammatory Bowel Disease: A Longitudinal Trajectory Study

Autorzy: Quirine M Bredero, Joke Fleer, Denise M Blom, Arno R Bourgonje, Gerard Dijkstra, Maya J Schroevers
Opublikowane w: Journal of Crohn's and Colitis, Numer 19, 2025, ISSN 1873-9946
Wydawca: Oxford University Press (OUP)
DOI: 10.1093/ECCO-JCC/JJAE163

Reasons for (Not) Seeking Care for Fatigue and Care Needs Among Patients With Inflammatory Bowel Disease: A Qualitative Interview Study

Autorzy: Quirine M. Bredero, Milou M. Ter Avest, Gerard Dijkstra, Joke Fleer, Maya J. Schroevers
Opublikowane w: Journal of Advanced Nursing, 2025, ISSN 0309-2402
Wydawca: Wiley
DOI: 10.1111/JAN.16837

The gut microbiome in end-stage lung disease and lung transplantation

Autorzy: Shuyan Zhang, J. Casper Swarte, Ranko Gacesa, Tim J. Knobbe, Daan Kremer, Bernadien H. Jansen, Martin H. de Borst, null null, Hermie J. M. Harmsen, Michiel E. Erasmus, Erik A. M. Verschuuren, Stephan J. L. Bakker, C. Tji Gan, Rinse K. Weersma, Johannes R. Björk, Coby Annema, Stephan J. L. Bakker, Stefan P. Berger, Hans Blokzijl, Frank A. J. A. Bodewes, Marieke T. de Boer, Kevin Damman, Martin H. de Borst, Arjan Diepstra, Gerard Dijkstra, Rianne M. Douwes, Caecilia S. E. Doorenbos, Michele F. Eisenga, Michiel E. Erasmus, C. Tji Gan, Eelko Hak, Bouke G. Hepkema, Frank Klont, Tim J. Knobbe, Daan Kremer, Henri G. D. Leuvenink, Willem S. Lexmond, Vincent E. de Meijer, Hubert G. M. Niesters, Gertrude J. Nieuwenhuis-Moeke, L. Joost van Pelt, Robert A. Pol, Robert J. Porte, Adelta V. Ranchor, Marion J. Siebelink, Riemer J. H. J. A. Slart, J. Casper Swarte, Daan J. Touw, Marius C. van den Heuvel, Coretta van Leer-Buter, Marco van Londen, Erik A. M. Verschuuren, Michel J. Vos, Rinse K. Weersma, Antonio W. Gomes Neto, Jan Stephan F. Sanders
Opublikowane w: mSystems, Numer 9, 2024, ISSN 2379-5077
Wydawca: American Society for Microbiology
DOI: 10.1128/MSYSTEMS.01312-23

Health-related quality of life is linked to the gut microbiome in kidney transplant recipients

Autorzy: J. Casper Swarte, Tim J. Knobbe, Johannes R. Björk, Ranko Gacesa, Lianne M. Nieuwenhuis, Shuyan Zhang, Arnau Vich Vila, Daan Kremer, Rianne M. Douwes, Adrian Post, Evelien E. Quint, Robert A. Pol, Bernadien H. Jansen, null null, C. Annema, F. A. J. A. Bodewes, M. T. de Boer, K. Damman, A. Diepstra, G. Dijkstra, C. S. E. Doorenbos, M. F. Eisenga, M. E. Erasmus, C. T. Gan, A. W. Gomes Neto, E. Hak, B. G. Hepkema, F. Klont, H. G. D. Leuvenink, W. S. Lexmond, G. J. Nieuwenhuis-Moeke, H. G. M. Niesters, L. J. van Pelt, A. V. Ranchor, J. S. F. Sanders, M. J. Siebelink, R. J. H. J. A. Slart, D. J. Touw, M. C. van den Heuvel, C. van Leer-Buter, M. van Londen, E. A. M. Verschuuren, M. J. Vos, Martin H. de Borst, Vincent E. de Meijer, Hans Blokzijl, Stefan P. Berger, Eleonora A. M. Festen, Alexandra Zhernakova, Jingyuan Fu, Hermie J. M. Harmsen, Stephan J. L. Bakker, Rinse K. Weersma
Opublikowane w: Nature Communications, Numer 14, 2023, ISSN 2041-1723
Wydawca: Springer Science and Business Media LLC
DOI: 10.1038/s41467-023-43431-8

Phage-display immunoprecipitation sequencing of the antibody epitope repertoire in inflammatory bowel disease reveals distinct antibody signatures

Autorzy: Arno R. Bourgonje; Sergio Andreu-Sánchez; Thomas Vogl; Shixian Hu; Arnau Vich Vila; Ranko Gacesa; Sigal Leviatan; Alexander Kurilshikov; Shelley Klompus; Iris N. Kalka; Hendrik M. van Dullemen; Adina Weinberger; Marijn C. Visschedijk; Eleonora A.M. Festen; Klaas Nico Faber; Cisca Wijmenga; Gerard Dijkstra; Eran Segal; Jingyuan Fu; Alexandra Zhernakova; Rinse K. Weersma
Opublikowane w: Immunity, Numer Vol. 56, issue 6, 2023, ISSN 1097-4180
Wydawca: Cell Press
DOI: 10.1016/j.immuni.2023.04.017