Computational, Chemical and Biotechnology Solutions to Improved DNA Data Storage: from In-Product Information and Cryptography to Long-Term Archiving

Informacje na temat projektu

DiDAX

Identyfikator umowy o grant: 101115134

DOI

10.3030/101115134

Data podpisania przez KE 3 Lipca 2023

Data rozpoczęcia 1 Listopada 2023

Data zakończenia 31 Października 2027

Finansowanie w ramach

• The European Innovation Council (EIC)

Koszt całkowity

€ 4 543 583,75

Wkład UE

€ 4 543 583,75

Koordynowany przez

TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY
Israel

CORDIS oferuje możliwość skorzystania z odnośników do publicznie dostępnych publikacji i rezultatów projektów realizowanych w ramach programów ramowych HORYZONT.

Odnośniki do rezultatów i publikacji związanych z poszczególnymi projektami 7PR, a także odnośniki do niektórych konkretnych kategorii wyników, takich jak zbiory danych i oprogramowanie, są dynamicznie pobierane z systemu OpenAIRE .

Rezultaty

Websites, patent fillings, videos etc. (1)

Website and project logo

Website and project logo information, also with social media links.

Documents, reports (3)

State of the art and market needs for authentication protocols

A report describing the state of the art and the commercial need for authentication and in-product documentation.

Plan for Communication and Dissemination Activities

Plan for Communication and Dissemination Activities including outline of workshops, plan for website improvements, and possibly other dissemination activities.

Report on Portfolio activities for reporting period 1

The report will present the collaboration activities that have been carried out in reporting period 1 and contain relevant materials (e.g., power point presentations, minutes of the meetings, etc.). It also explains how the Portfolio activities and the EIC proactive project management approach contribute to the achievement the project objectives and help the transition to market.The report will be submitted at the end reporting period 1 and will be assessed in the context of projects review for the corresponding reporting period (M12).

Data Management Plan (1)

Data Management Plan

Data Management Plan established and described.

Publikacje

Conference proceedings (20)

Constrained Coding for Composite DNA: Channel Capacity and Efficient Constructions

Autorzy: Tuan Thanh Nguyen, Chen Wang, Kui Cai, Yiwei Zhang, Zohar Yakhini
Opublikowane w: 2025 IEEE International Symposium on Information Theory (ISIT), 2025
Wydawca: IEEE
DOI: 10.48550/ARXIV.2501.10645

Sequence Reconstruction Over Coloring Channels for Protein Identification

Autorzy: Jessica Bariffi, Antonia Wachter-Zeh, Eitan Yaakobi
Opublikowane w: 2025 IEEE International Symposium on Information Theory (ISIT), 2025
Wydawca: IEEE
DOI: 10.48550/ARXIV.2508.02229

Complex DNA Synthesis Sequences

Autorzy: Boaz Moav, Eitan Yaakobi, Ryan Gabrys
Opublikowane w: 2025 IEEE International Symposium on Information Theory (ISIT), 2025
Wydawca: IEEE
DOI: 10.48550/ARXIV.2510.21253

Correcting Multiple Substitutions in Nanopore-Sequencing Reads

Autorzy: Anisha Banerjee, Yonatan Yehezkeally, Antonia Wachter-Zeh, Eitan Yaakobi
Opublikowane w: 2025 IEEE International Symposium on Information Theory (ISIT), 2025
Wydawca: IEEE
DOI: 10.48550/ARXIV.2505.02447

Near Optimal Code Construction for the Adversarial Torn Paper Channel with Edit Errors

Autorzy: Maria Abu-Sini, Reinhard Heckel
Opublikowane w: 2025 IEEE International Symposium on Information Theory (ISIT), 2025
Wydawca: IEEE
DOI: 10.48550/ARXIV.2601.14088

DeepDIVE: Optimizing Input-Constrained Distributions for Composite DNA Storage via Multinomial Channel

Autorzy: Adir Kobovich, Eitan Yaakobi, Nir Weinberger
Opublikowane w: 2025 IEEE International Symposium on Information Theory (ISIT), 2025
Wydawca: IEEE
DOI: 10.48550/ARXIV.2501.15172

Coding for Ordered Composite DNA Sequences

Autorzy: Besart Dollma, Ohad Elishco, Eitan Yaakobi
Opublikowane w: 2025 IEEE International Symposium on Information Theory (ISIT), 2025
Wydawca: IEEE
DOI: 10.48550/ARXIV.2509.26119

Coding for Composite DNA to Correct Substitutions, Strand Losses, and Deletions

Autorzy: Frederik Walter, Omer Sabary, Antonia Wachter-Zeh, Eitan Yaakobi
Opublikowane w: 2024 IEEE International Symposium on Information Theory (ISIT), 2024
Wydawca: IEEE
DOI: 10.1109/ISIT57864.2024.10619202

An Optimal Sequence Reconstruction Algorithm for Reed-Solomon Codes

Autorzy: Shubhransh Singhvi, Roni Con, Han Mao Kiah, Eitan Yaakobi
Opublikowane w: 2024 IEEE International Symposium on Information Theory (ISIT), 2024
Wydawca: IEEE
DOI: 10.1109/ISIT57864.2024.10619163

Decoding Insertions/Deletions via List Recovery

Autorzy: Anisha Banerjee, Roni Con, Antonia Wachter-Zeh, Eitan Yaakobi
Opublikowane w: 2025 IEEE International Symposium on Information Theory (ISIT), 2025
Wydawca: IEEE
DOI: 10.48550/ARXIV.2505.02452

Coding for Synthesis Defects

Autorzy: Ziyang Lu, Han Mao Kiah, Yiwei Zhang, Robert N. Grass, Eitan Yaakobit
Opublikowane w: 2024 IEEE Information Theory Workshop (ITW), 2024
Wydawca: IEEE
DOI: 10.48550/ARXIV.2405.02080

The Labeled Coupon Collector Problem

Autorzy: Andrew Tan, Oriel Limor, Daniella Bar-Lev, Ryan Gabrys, Zohar Yakhini, Paul H. Siegel
Opublikowane w: 2025 IEEE Information Theory Workshop (ITW), 2025
Wydawca: IEEE
DOI: 10.48550/ARXIV.2507.15231

Error-Correcting Codes for Labeled DNA Sequences

Autorzy: Dganit Hanania, Eitan Yaakobi
Opublikowane w: 2025 IEEE International Symposium on Information Theory (ISIT), 2025
Wydawca: IEEE
DOI: 10.48550/ARXIV.2511.01280

Coding for Strand Breaks in Composite DNA

Autorzy: Frederik Walter, Yonatan Yehezkeally
Opublikowane w: 2025 IEEE International Symposium on Information Theory (ISIT), 2025
Wydawca: IEEE
DOI: 10.48550/ARXIV.2501.15851

Correcting a Single Deletion in Reads from a Nanopore Sequencer

Autorzy: Anisha Banerjee, Yonatan Yehezkeally, Antonia Wachter-Zeh, Eitan Yaakobi
Opublikowane w: 2024 IEEE International Symposium on Information Theory (ISIT), 2024
Wydawca: IEEE
DOI: 10.1109/ISIT57864.2024.10619468

Sequential Decoding of Multiple Traces Over the Syndrome Trellis for Synchronization Errors

Autorzy: Anisha Banerjee, Lorenz Welter, Alexandre Graell I Amat, Antonia Wachter-Zeh, Eirik Rosnes
Opublikowane w: ICASSP 2025 - 2025 IEEE International Conference on Acoustics, Speech and Signal Processing (ICASSP), 2025
Wydawca: IEEE
DOI: 10.48550/ARXIV.2410.07120

Studying the Cycle Complexity of DNA Synthesis

Autorzy: Amit Zrihan, Eitan Yaakobi, Zohar Yakhini
Opublikowane w: 2024 IEEE Information Theory Workshop (ITW), 2024
Wydawca: IEEE
DOI: 10.48550/ARXIV.2412.05865

Error-Correcting Codes for Combinatorial Composite DNA

Autorzy: Omer Sabary, Inbal Preuss, Ryan Gabrys, Zohar Yakhini, Leon Anavy, Eitan Yaakobi
Opublikowane w: 2024 IEEE International Symposium on Information Theory (ISIT), 2024
Wydawca: IEEE
DOI: 10.1109/ISIT57864.2024.10619334

Rank Modulated Composite Encoding for Data Storage in DNA

Autorzy: Tomer Cohen, Zhiying Wang, Eitan Yaakobi, Zohar Yakhini
Opublikowane w: 2025 13th International Symposium on Topics in Coding (ISTC), 2025
Wydawca: IEEE
DOI: 10.1109/ISTC65386.2025.11154607

Representing Information on DNA Using Patterns Induced by Enzymatic Labeling

Autorzy: Daniella Bar-Lev, Tuvi Etzion, Eitan Yaakobi, Zohar Yakhini
Opublikowane w: 2024 IEEE International Symposium on Information Theory (ISIT), 2024
Wydawca: IEEE
DOI: 10.1109/ISIT57864.2024.10619227

Peer reviewed articles (20)

More on codes for combinatorial composite DNA

Autorzy: Zuo Ye, Omer Sabary, Ryan Gabrys, Eitan Yaakobi, Ohad Elishco
Opublikowane w: Designs, Codes and Cryptography, Numer 93, 2025, ISSN 0925-1022
Wydawca: Springer Science and Business Media LLC
DOI: 10.1007/S10623-025-01634-8

Sequencing Coverage Analysis for Combinatorial DNA-Based Storage Systems

Autorzy: Inbal Preuss, Ben Galili, Zohar Yakhini, Leon Anavy
Opublikowane w: IEEE Transactions on Molecular, Biological, and Multi-Scale Communications, Numer 10, 2024, ISSN 2372-2061
Wydawca: Institute of Electrical and Electronics Engineers (IEEE)
DOI: 10.1109/TMBMC.2024.3408053

Error characterization and error correction approaches in combinatorial DNA-based storage

Autorzy: Inbal Preuss, Omer Sabary, Ryan Gabrys, Zohar Yakhini, Eitan Yaakobi, Leon Anavy
Opublikowane w: Scientific Reports, Numer 16, 2026, ISSN 2045-2322
Wydawca: Springer Science and Business Media LLC
DOI: 10.1038/S41598-026-38599-0

Sequence Reconstruction for Substitution Channel: New Sufficient Conditions and Algorithms

Autorzy: Chen Wang, Eitan Yaakobi, Yiwei Zhang
Opublikowane w: IEEE Transactions on Information Theory, Numer 72, 2026, ISSN 0018-9448
Wydawca: Institute of Electrical and Electronics Engineers (IEEE)
DOI: 10.48550/ARXIV.2606.05454

DNA-Based Chemical Unclonable Functions for Cryptographic Anticounterfeit Tagging of Pharmaceuticals

Autorzy: Anne M. Luescher, Wendelin J. Stark, Robert N. Grass
Opublikowane w: ACS Nano, Numer 18, 2024, ISSN 1936-0851
Wydawca: American Chemical Society (ACS)
DOI: 10.1021/acsnano.4c10870

Efficiency of Digital Photolithographic Synthesis of Large, High-Quality DNA Libraries and Microarrays using a Guanine O6 Dephosphitylation Strategy

Autorzy: Santra Santhosh, Sharon Istvánffy, Omer Sabary, Eitan Yaakobi, Maya Giridhar, Jürgen Behr, Mark M. Somoza
Opublikowane w: Communications Chemistry, Numer 8, 2025, ISSN 2399-3669
Wydawca: Springer Science and Business Media LLC
DOI: 10.26434/CHEMRXIV-2025-F706F

Channels with Input-Correlated Synchronization Errors

Autorzy: Roni Con, João Ribeiro
Opublikowane w: IEEE Transactions on Information Theory, 2026, ISSN 0018-9448
Wydawca: Institute of Electrical and Electronics Engineers (IEEE)
DOI: 10.48550/ARXIV.2504.14087

Robust Gray Codes Approaching the Optimal Rate

Autorzy: Roni Con, Dorsa Fathollahi, Ryan Gabrys, Mary Wootters, Eitan Yaakobi
Opublikowane w: IEEE Transactions on Information Theory, Numer 71, 2025, ISSN 0018-9448
Wydawca: Institute of Electrical and Electronics Engineers (IEEE)
DOI: 10.48550/ARXIV.2406.17689

Challenges for error-correction coding in DNA data storage: photolithographic synthesis and DNA decay

Autorzy: Andreas L. Gimpel, Wendelin J. Stark, Reinhard Heckel, Robert N. Grass
Opublikowane w: Digital Discovery, 2024, ISSN 2635-098X
Wydawca: Royal Society of Chemistry (RSC)
DOI: 10.1039/D4DD00220B

Exploring the intersection of natural sciences and information technology via entropy and randomness

Autorzy: Anne M. Luescher, Reinhard Heckel, Robert N. Grass
Opublikowane w: Nature Communications, Numer 16, 2025, ISSN 2041-1723
Wydawca: Springer Science and Business Media LLC
DOI: 10.3929/ETHZ-C-000782746

One Code Fits All: Strong Stuck-At Codes for Versatile Memory Encoding

Autorzy: Roni Con, Ryan Gabrys, Eitan Yaakobi
Opublikowane w: IEEE Transactions on Information Theory, Numer 71, 2025, ISSN 0018-9448
Wydawca: Institute of Electrical and Electronics Engineers (IEEE)
DOI: 10.48550/ARXIV.2403.19061

Anonymous Shamir’s Secret-Sharing via Reed–Solomon Codes Against Permutations, Insertions, and Deletions

Autorzy: Roni Con
Opublikowane w: IEEE Transactions on Information Theory, Numer 71, 2025, ISSN 0018-9448
Wydawca: Institute of Electrical and Electronics Engineers (IEEE)
DOI: 10.48550/ARXIV.2412.17003

Error-Correcting Codes for Nanopore Sequencing

Autorzy: Anisha Banerjee, Yonatan Yehezkeally, Antonia Wachter-Zeh, Eitan Yaakobi
Opublikowane w: IEEE Transactions on Information Theory, Numer 70, 2024, ISSN 0018-9448
Wydawca: Institute of Electrical and Electronics Engineers (IEEE)
DOI: 10.1109/TIT.2024.3380615

Large‐Scale Distribution of Physical Data Using DNA‐of‐Things Technology in Newspaper Printing

Autorzy: Francesca Granito, Andreas L. Gimpel, Wendelin J. Stark, Reinhard Heckel, Robert N. Grass
Opublikowane w: Small, Numer 22, 2026, ISSN 1613-6810
Wydawca: Wiley
DOI: 10.1002/SMLL.202511931

Efficient DNA-based data storage using shortmer combinatorial encoding

Autorzy: Inbal Preuss, Michael Rosenberg, Zohar Yakhini, Leon Anavy
Opublikowane w: Scientific Reports, Numer 14, 2024, ISSN 2045-2322
Wydawca: Springer Science and Business Media LLC
DOI: 10.1038/s41598-024-58386-z

Improved Constructions of Linear Codes for Insertions and Deletions

Autorzy: Roee Gross, Roni Con, Eitan Yaakobi
Opublikowane w: IEEE Transactions on Information Theory, Numer 72, 2026, ISSN 0018-9448
Wydawca: Institute of Electrical and Electronics Engineers (IEEE)
DOI: 10.48550/ARXIV.2509.26077

Color-corrected and high-contrast catadioptric relay for maskless high-resolution nucleic acid photolithography

Autorzy: Timm Michel, Jürgen Behr, Hamed Sabzalipoor, Gisela Ibáñez-Redín, Jory Lietard, Thomas Schletterer, Max Funck, Mark M. Somoza
Opublikowane w: Optics Express, Numer 33, 2025, ISSN 1094-4087
Wydawca: Optica Publishing Group
DOI: 10.48550/ARXIV.2411.06466

Comparison of state-of-the-art error-correction coding for sequence-based DNA data storage

Autorzy: Andreas L. Gimpel, Alex Remschak, Wendelin J. Stark, Reinhard Heckel, Robert N. Grass
Opublikowane w: Nature Communications, Numer 17, 2026, ISSN 2041-1723
Wydawca: Springer Science and Business Media LLC
DOI: 10.1101/2025.07.11.664297

Reed–Solomon Codes Against Insertions and Deletions: Full-Length and Rate-1/2 Codes

Autorzy: Peter Beelen, Roni Con, Anina Gruica, Maria Montanucci, Eitan Yaakobi
Opublikowane w: IEEE Transactions on Information Theory, Numer 72, 2026, ISSN 0018-9448
Wydawca: Institute of Electrical and Electronics Engineers (IEEE)
DOI: 10.48550/ARXIV.2501.11371

Cover Your Bases: How to Minimize the Sequencing Coverage in DNA Storage Systems

Autorzy: Daniella Bar-Lev, Omer Sabary, Ryan Gabrys, Eitan Yaakobi
Opublikowane w: IEEE Transactions on Information Theory, Numer 71, 2025, ISSN 0018-9448
Wydawca: Institute of Electrical and Electronics Engineers (IEEE)
DOI: 10.48550/ARXIV.2305.05656

Other (1)

An open-source advanced maskless synthesizer for light-directed chemical synthesis of large nucleic acid libraries and microarrays

Autorzy: Jürgen Behr, Timm Michel, Maya Giridhar, Santra Santhosh, Arya Das, Hamed Sabzalipoor, Tadija Kekić, Etkin Parlar, Igor Ilić, Gisela Ibáñez-Redín, Erika Schaudy, Jory Lietard, Thomas Schletterer, Max Funck, Mark Somoza
Opublikowane w: 2024
Wydawca: American Chemical Society (ACS)
DOI: 10.26434/chemrxiv-2024-j4c90