Cel Cognitive Neuroscience throughout the last decade was dominated by a two stream model of visual processing. A ventral pathway was presumed to be dedicated to perception-related processing. A dorsal pathway was presumed to be dedicated to action-related processing. The proposed project challenges this view combining neuroimaging and neuropsychological methods. Neuroimaging in healthy humans allows for a view on correlated activity of the intact perception-action system, patients with visuomotor deficits reveal causalities between perception- and action-related information processing and the demonstration of neural reorganisation. However, neuroimaging studies including patients with brain lesions have rarely been conducted. Patients with optic ataxia after brain damage demonstrate specific visuomotor disorders: (i) deficient grip scaling to object size and (ii) spatial mismatch between perceived positions and goal-directed hand movements. These deficits vary with temporal parameters and knowledge about the object to be grasped and/or manipulated. Furthermore, the patients seem to adopt cognitive strategies to improve their performance. Therefore, they allow for the investigation of interactions between visual perception, spatial memory, and cognitive processing for the purpose of goal-directed action control. The proposed project comprises behavioural experiments to reveal the impact of object/action knowledge on movement control and of movement timing in optic ataxia patients. Investigations of reaching and grasping using functional magnetic resonance imaging (fMRI) and transcranial magnetic stimulation in healthy subjects and patients complement the neuropsychological research approach. The analysis of specific activation patterns and behavioural changes upon TMS application in patients - under consideration of their individual brain damage - in comparison with large groups of healthy controls will allow for a causal description of human visual action control. Dziedzina nauki natural sciencesbiological sciencesneurobiologycognitive neuroscienceengineering and technologymedical engineeringdiagnostic imagingmagnetic resonance imagingnatural sciencescomputer and information sciencesdata sciencedata processing Słowa kluczowe optic ataxia visuomotor control Program(-y) FP7-IDEAS-ERC - Specific programme: "Ideas" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Temat(-y) ERC-SG-LS4 - ERC Starting Grant - Physiology, Pathophysiology and Endocrinology Zaproszenie do składania wniosków ERC-2007-StG Zobacz inne projekty w ramach tego zaproszenia System finansowania ERC-SG - ERC Starting Grant Instytucja przyjmująca EBERHARD KARLS UNIVERSITAET TUEBINGEN Wkład UE € 1 120 440,00 Adres GESCHWISTER-SCHOLL-PLATZ 72074 Tuebingen Niemcy Zobacz na mapie Region Baden-Württemberg Tübingen Tübingen, Landkreis Rodzaj działalności Higher or Secondary Education Establishments Kontakt administracyjny Andreas Rothfuß (Dr.) Kierownik naukowy Marc Himmelbach (Dr.) Linki Kontakt z organizacją Opens in new window Strona internetowa Opens in new window Koszt całkowity Brak danych Beneficjenci (1) Sortuj alfabetycznie Sortuj według wkładu UE Rozwiń wszystko Zwiń wszystko EBERHARD KARLS UNIVERSITAET TUEBINGEN Niemcy Wkład UE € 1 120 440,00 Adres GESCHWISTER-SCHOLL-PLATZ 72074 Tuebingen Zobacz na mapie Region Baden-Württemberg Tübingen Tübingen, Landkreis Rodzaj działalności Higher or Secondary Education Establishments Kontakt administracyjny Andreas Rothfuß (Dr.) Kierownik naukowy Marc Himmelbach (Dr.) Linki Kontakt z organizacją Opens in new window Strona internetowa Opens in new window Koszt całkowity Brak danych
