Skip to main content

Identification of novel protein kinases required for meiosis

Cel

During meiosis, one round of DNA replication is followed by two rounds of cell division. This results in production of four haploid cells from a diploid precursor. Proteins required for this reduction of chromosome number are largely unknown. In this project, we want to identify novel proteins required for meiotic chromosome segregation. Protein kinases are the key cellular regulators and some of them are known to be essential for proper segregation of chromosomes during meiosis. We now want to look at protein kinases essential for mitotic growth and identify those required for chromosome segregation during meiosis. We want to take advantage of chemical genetics and construct conditional alleles of protein kinases sensitive to small molecule inhibitors (analog sensitive alleles). We want to use these alleles to determine which of protein kinases essential for mitotic growth are required for chromosome segregation during meiosis.

Zaproszenie do składania wniosków

FP7-PEOPLE-2007-2-1-IEF
Zobacz inne projekty w ramach tego zaproszenia

Koordynator

UNIVERSITAT WIEN
Adres
Universitatsring 1
1010 Wien
Austria

Zobacz na mapie

Rodzaj działalności
Higher or Secondary Education Establishments
Kontakt administracyjny
Juraj Gregan (Dr.)
Wkład UE
€ 167 393,24