Cel
Metal catalyzed C-H bond functionalization reactions is an area of organic synthesis having an exponential development and a great acceptation in the chemist community because meets the ideals of green chemistry. In this proposal we present a project research based on the development of new strategies of C-H bond activation/cycloaddition that leads to the formation of functionalized heterocycles. Furthermore the methodology is proposed to be applied to the synthesis of piperidine acid analogs, known prenyltransferase inhibitors. The inhibition of prenyltransferases could prevent the proper functioning of the Ras (protein), which is commonly abnormally active in cancer, and it could be key for the development of new therapeutics in the fight against this widespread illness.
Dziedzina nauki
Zaproszenie do składania wniosków
FP7-PEOPLE-2009-RG
Zobacz inne projekty w ramach tego zaproszenia
System finansowania
MC-ERG - European Re-integration Grants (ERG)Koordynator
15782 Santiago De Compostela
Hiszpania