Cel Cancer is rapidly becoming the greatest health hazard of our days. The most widespread cancers, are lung cancer (LC), breast cancer (BC), colorectal cancer (CC), and prostate cancer (PC). The impact of the various techniques used for diagnosis, screening and monitoringthese cancers is either uncertain and/or inconvenient for the patients. This proposal aims to create a low-cost, easy-to-use and noninvasive screening method for LC, BC, CC, and PC based on breath testing with a novel nanosensors approach. With this in mind, we propose to:(a) modify an array of nanosensors based on Au nanoparticles for obtaining highly-sensitive detection levels of breath biomarkers of cancer; and(b) investigate the use of the developed array in a clinical study.Towards this end, we will collect suitable breath samples from patients and healthy controls in a clinical trial and test the feasibility of the device to detect LC, BC, CC, and PC, also in the presence of other diseases.We will then investigate possible ways to identify the stage of the disease, monitor the response to cancertreatment, and to identify cancer subtypes. Further, we propose that the device can be used for monitoring of cancer patients during and after treatment. The chemical nature of the cancer biomarkers will be identified through spectrometry techniques.The proposed approach would be used outside specialist settings and could considerably lessen the burden on the health budgets, both through the low cost of the proposed all-inclusive cancer test, and through earlier and, hence, more cost-effective cancer treatment. Dziedzina nauki medical and health sciencesclinical medicineoncologyprostate cancermedical and health sciencesclinical medicineoncologylung cancermedical and health sciencesclinical medicineoncologybreast cancermedical and health sciencesclinical medicineoncologycolorectal cancerengineering and technologynanotechnologynano-materials Program(-y) FP7-IDEAS-ERC - Specific programme: "Ideas" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Temat(-y) ERC-SG-LS7 - Applied life sciences, biotechnology and bioengineering: agricultural, animal, fishery, forestry/food sciences; biotechnology, chemical biology, genetic engineering, synthetic biology, industrial biosciences; environmental biotechnology. Zaproszenie do składania wniosków ERC-2010-StG_20091118 Zobacz inne projekty w ramach tego zaproszenia System finansowania ERC-SG - ERC Starting Grant Instytucja przyjmująca TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY Wkład UE € 1 200 000,00 Adres SENATE BUILDING TECHNION CITY 32000 Haifa Izrael Zobacz na mapie Rodzaj działalności Higher or Secondary Education Establishments Kierownik naukowy Hossam Haick (Dr.) Kontakt administracyjny Mark Davison (Mr.) Linki Kontakt z organizacją Opens in new window Strona internetowa Opens in new window Koszt całkowity Brak danych Beneficjenci (1) Sortuj alfabetycznie Sortuj według wkładu UE Rozwiń wszystko Zwiń wszystko TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY Izrael Wkład UE € 1 200 000,00 Adres SENATE BUILDING TECHNION CITY 32000 Haifa Zobacz na mapie Rodzaj działalności Higher or Secondary Education Establishments Kierownik naukowy Hossam Haick (Dr.) Kontakt administracyjny Mark Davison (Mr.) Linki Kontakt z organizacją Opens in new window Strona internetowa Opens in new window Koszt całkowity Brak danych
