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Zawartość zarchiwizowana w dniu 2024-05-30

Cytokine Receptor Signaling Revisited: Implementing novel concepts for cytokine-based therapies

Cel

Cytokine receptor signaling is an essential part of the intercellular communication networks that govern key physiological processes in the body. Cytokine dysfunction is associated with numerous pathologies including autoimmune disorders and cancer, and both cytokines and cytokine antagonists have found their way into the clinic. Yet, there are still many unfulfilled promises and opportunities. In this project we will reinvestigate key aspects of cytokine receptor activation and signaling using novel insights and techniques recently developed in our laboratory. This will include the AcTakine concept for cell-specific targeting of cytokine activity, and applications of our MAPPIT, KISS and Virotrap toolboxes to systematically map protein interactions involved in cytokine signaling. We expect to obtain important new insights, both in fundamental and in applied medical sciences.

Zaproszenie do składania wniosków

ERC-2013-ADG
Zobacz inne projekty w ramach tego zaproszenia

System finansowania

ERC-AG - ERC Advanced Grant

Instytucja przyjmująca

VIB VZW
Wkład UE
€ 2 487 728,40
Adres
SUZANNE TASSIERSTRAAT 1
9052 ZWIJNAARDE - GENT
Belgia

Zobacz na mapie

Region
Vlaams Gewest Prov. Oost-Vlaanderen Arr. Gent
Rodzaj działalności
Research Organisations
Kierownik naukowy
Jan Tavernier (Prof.)
Kontakt administracyjny
Rik Audenaert (Mr.)
Linki
Koszt całkowity
Brak danych

Beneficjenci (1)