Cel The goal of this research project is to study and develop novel synergistic technologies for the next generation of high performance biochips, for future applications e.g. in accelerated drug discovery, diagnostics and personalized medicine. One of the key technologies relies on a predictable self-organization of fluids, using both static and dynamic formats will be utilized. The formats will be combined to overcome current bottlenecks in the automation of high throughput assays, and will also be used for the development of a new concept for automated chip replication. Other complementary technologies deal with surface-expanded high-density bio probe arrays, including the use of novel polymers. Also, novel magnetic bio Nan wires, controlled by an external magnetic field onto a platform of magnetic handouts, will be explored. It is anticipated that the use of these technologies will provide unique possibilities to increase legend density, as well as enhanced kinetics, resulting in enhanced sensitivity and faster assay performance. A third technology based on externally applied surface acoustic waves will be incorporated into the platform, yielding extremely efficient agitation of Nan droplets. Finally, a Nan electrochemical detection system will be developed. The technologies will be combined to yield an optimised Nan array chip, including the novel fluid agitation and bio-Nan wires principles. The optimised structure will be tested using standard bioassays, and the results obtained will be compared with performance data, obtained from similar experiments with state of the art biochips. Dziedzina nauki medical and health sciencesbasic medicinepharmacology and pharmacydrug discoverysocial sciencessociologyindustrial relationsautomationnatural scienceschemical sciencespolymer sciencesmedical and health scienceshealth sciencespersonalized medicineengineering and technologynanotechnologynano-materials Słowa kluczowe Nanotechnology biochip magnetic particles nanofluids nanopillars nanowires replication Program(-y) FP6-NMP - Nanotechnologies and nanosciences, knowledge-based multifunctional materials and new production processes and devices: thematic priority 3 under the 'Focusing and integrating community research' of the 'Integrating and strengthening the European Research Area' specific programme 2002-2006. Temat(-y) NMP-2002-3.4.1.1-2 - Self-organisation and self-assembling NMP-2002-3.4.1.2-1 - Interfaces between biological and non biological entities Zaproszenie do składania wniosków FP6-2002-NMP-1 Zobacz inne projekty w ramach tego zaproszenia System finansowania STREP - Specific Targeted Research Project Koordynator KUNGLIGA TEKNISKA HOEGSKOLAN Wkład UE Brak danych Adres Valhallavaegen, 79 10044 STOCKHOLM Szwecja Zobacz na mapie Koszt całkowity Brak danych Uczestnicy (5) Sortuj alfabetycznie Sortuj według wkładu UE Rozwiń wszystko Zwiń wszystko INSTITUT CURIE Francja Wkład UE Brak danych Adres 26, rue d'Ulm PARIS Zobacz na mapie Koszt całkowity Brak danych NATURWISSENSCHAFTLICHES UND MEDIZINISCHES INSTITUT AN DER UNIVERSITAET TUEBINGEN Niemcy Wkład UE Brak danych Adres Markwiesenstrasse 55 REUTLINGEN Zobacz na mapie Koszt całkowity Brak danych ECOLE NORMALE SUPERIEURE Francja Wkład UE Brak danych Adres 45 Rue D'Ulm PARIS Zobacz na mapie Koszt całkowity Brak danych DIAGNOSWISS SA Szwajcaria Wkład UE Brak danych Adres Route de l'Ile-au-Bois 2, C/o Cimo S.A., Case Postale MONTHEY Zobacz na mapie Koszt całkowity Brak danych ADVALYTIX AG Niemcy Wkład UE Brak danych Adres Eugen-Saenger-Strasse 53 BRUNNTHAL Zobacz na mapie Koszt całkowity Brak danych
