Skip to main content
Przejdź do strony domowej Komisji Europejskiej (odnośnik otworzy się w nowym oknie)
polski pl
CORDIS - Wyniki badań wspieranych przez UE
CORDIS
Zawartość zarchiwizowana w dniu 2024-06-18

The development of a chairside diagnostic biomarker assay to assess metabolic activity with inflammatory diseases

Cel

The project is concerned with the development of a chairside immunoassay for the detection and quantitation of biomarkers indicating inflammatory and jawbone destruction in dentistry. Specific bone matrix proteins have been identified in gingival crevicula r fluid (serum based fluid collected about teeth) in clinical conditions where active resorption of tooth supporting bone is highly probable and thus proposed as ideal biomarkers to determine the health status of deep unseen dental tissues. The assay consi dered in the project is the first prototype of a new line of diagnostic products to be developed jointly by the participants. The assay to be developed is noninvasive and aims at measuring the marker in crevicular fluid collected at tooth base on paper str ips. The immunoassay will use coloured nanoparticles for its development so that it can be read by the dental surgeon at the patient's side. The test is expected to offer more relevant information on the pathological process than currently available diagno stic procedures, allowing for quicker therapeutic handling. The test will be developed jointly by the Dental School at the University of Wales College of Medicine which identified and purified the marker, and Englebienne and Associates, a Belgian SME spe cialised in developing rapid diagnostic tests. For the project purpose, a post-doctoral student from the academic partner (who has an understanding of teeth supporting tissues and biomarkers in health and disease) will be hosted by the SME for training dur ing active product development. They will then assist in clinical validation co-ordinated by the academic partner. In the longer term, the collaboration established is intended to secure the shared development and commercialisation by the participants of a complete line of diagnostic immunoassay products for dentistry and stomatology. The project also intends to create the basis for a European centre of excellence in dental diagnostics benefiting society at large.

Dziedzina nauki (EuroSciVoc)

Temat(-y)

Zaproszenie do składania wniosków

FP6-2002-MOBILITY-3
Zobacz inne projekty w ramach tego zaproszenia

System finansowania

TOK - Marie Curie actions-Transfer of Knowledge

Koordynator

UNIVERSITY OF WALES COLLEGE OF MEDICINE
Wkład UE
Brak danych
Adres
Health Park Cardigan House
CARDIFF
Zjednoczone Królestwo
Koszt całkowity
Brak danych

Uczestnicy (1)