Active and Healthy Ageing is at the core of the European Union (EU) strategy on demographic change. The unprecedented ageing of the EU population is having deep and extended consequences for individuals, businesses, industry players, national and regional public authorities, governments, health and care organisations, policy-makers and the investment community. Although demographic change represents a societal challenge for Europe, it also offers new opportunities for innovation and economic growth, particularly in the digital economy. Innovative digital health solutions can support healthier lifestyles and empower citizens to manage their own health conditions, yet still meet the expectations of patients and carers. While several initiatives, including “Innovation to Market” and “Blueprint – Digital transformation of Health and Care for the ageing society” – have been recently launched across Europe for mobilising competences, resources and knowledge, and boost investments, the European Innovation Partnership on Active and Healthy Ageing (EIPonAHA) remains one of the leading actions promoted by the EU in this sector. PROEIPAHA has successfully supported the execution of the initiative jointly with the European Commission (EC) and the broad audience of EIPonAHA stakeholders securing the basis for further development and the reinforcement of a complex ecosystem dealing with research and innovation priorities, policy visions, standardisation issues, public procurement opportunities, engagement, and cross-fertilisation methods. PROEIPAHA has fostered the awareness and encouraged the involvement of the Partnership’s members through a set of administrative services, coordination mechanisms, online tools, as well as dissemination and coordination activities. PROEIPAHA has targeted the objective to enhance the six EIPonAHA Action Groups accelerating the adoption of innovation in the field of adherence to treatments, fall prevention, frailty, integrated care, interoperable independent living solutions and age-friendly environments.