Molecular mechanisms of induced protection against sepsis by DNA damage responses

DNA damage independent inhibition of NF-κB transcription by anthracyclines

Autorzy: Angelo Chora, Dora Pedroso, Nadja Pejanovic, Eleni Kyriakou, Henrique Colaço, Raffaella Gozzelino, André Barros, Katharina Willmann, Tiago Velho, Catarina F. Moita, Isa Santos, Pedro Pereira, Sílvia Carvalho, Filipa Martins, João A. Ferreira, Sérgio Fernandes de Almeida, Vladimir Benes, Josef Anrather, Miguel P. Soares, Arie Geerlof, Jacques Neefjes, Michael Sattler, Ana C. Messias, Ana Neves
Opublikowane w: BioRxiv, 2019
Wydawca: BioRxiv
DOI: 10.1101/2020.04.27.065003

Tetracycline Antibiotics Induce Host-Dependent Disease Tolerance to Infection

Autorzy: Henrique G. Colaço, André Barros, Ana Neves-Costa, Elsa Seixas, Dora Pedroso, Tiago Velho, Katharina L. Willmann, Pedro Faisca, Gerlinde Grabmann, Hyon-Seung Yi, Minho Shong, Vladimir Benes, Sebastian Weis, Thomas Köcher, Luís F. Moita
Opublikowane w: Immunity, Numer 54/1, 2021, Strona(/y) 53-67.e7, ISSN 1074-7613
Wydawca: Cell Press
DOI: 10.1016/j.immuni.2020.09.011

CD11b activation suppresses TLR-dependent inflammation and autoimmunity in systemic lupus erythematosus

Autorzy: Mohd Hafeez Faridi, Samia Q. Khan, Wenpu Zhao, Ha Won Lee, Mehmet M. Altintas, Kun Zhang, Vinay Kumar, Andrew R. Armstrong, Carmelo Carmona-Rivera, Jessica M. Dorschner, Abigail M. Schnaith, Xiaobo Li, Yogita Ghodke-Puranik, Erica Moore, Monica Purmalek, Jorge Irizarry-Caro, Tingting Zhang, Rachael Day, Darren Stoub, Victoria Hoffmann, Shehryar Jehangir Khaliqdina, Prachal Bhargava, Ana M. Santand
Opublikowane w: Journal of Clinical Investigation, Numer 127/4, 2017, Strona(/y) 1271-1283, ISSN 0021-9738
Wydawca: American Society for Clinical Investigation
DOI: 10.1172/jci88442

shRNA-Based Screen Identifies Endocytic Recycling Pathway Components That Act as Genetic Modifiers of Alpha-Synuclein Aggregation, Secretion and Toxicity

Autorzy: Susana A. Gonçalves, Diana Macedo, Helena Raquel, Pedro D. Simões, Flaviano Giorgini, José S. Ramalho, Duarte C. Barral, Luís Ferreira Moita, Tiago Fleming Outeiro
Opublikowane w: PLOS Genetics, Numer 12/4, 2016, Strona(/y) e1005995, ISSN 1553-7404
Wydawca: PLoS
DOI: 10.1371/journal.pgen.1005995

Ribosome-Targeting Antibiotics Impair T Cell Effector Function and Ameliorate Autoimmunity by Blocking Mitochondrial Protein Synthesis

Autorzy: Luís Almeida, Ayesha Dhillon-LaBrooy, Carla N. Castro, Nigatu Adossa, Guilhermina M. Carriche, Melanie Guderian, Saskia Lippens, Sven Dennerlein, Christina Hesse, Bart N. Lambrecht, Luciana Berod, Leif Schauser, Bruce R. Blazar, Markus Kalesse, Rolf Müller, Luís F. Moita, Tim Sparwasser
Opublikowane w: Immunity, Numer 54/1, 2021, Strona(/y) 68-83.e6, ISSN 1074-7613
Wydawca: Cell Press
DOI: 10.1016/j.immuni.2020.11.001

Sepsis: the need for tolerance not complacency

Autorzy: TR Velho, I Santos, P Póvoa, Moita Ferreira
Opublikowane w: Swiss Medical Weekly, 2016, ISSN 1424-7860
Wydawca: EMH Swiss Medical Publishers Ltd
DOI: 10.4414/smw.2016.14276

Initiation of innate immune responses by surveillance of homeostasis perturbations

Autorzy: Henrique G. Colaço, Luis F. Moita
Opublikowane w: The FEBS Journal, Numer 283/13, 2016, Strona(/y) 2448-2457, ISSN 1742-464X
Wydawca: Blackwell Publishing Inc.
DOI: 10.1111/febs.13730

Disease tolerance and immunity in host protection against infection

Autorzy: Miguel P. Soares, Luis Teixeira, Luis F. Moita
Opublikowane w: Nature Reviews Immunology, Numer 17/2, 2017, Strona(/y) 83-96, ISSN 1474-1733
Wydawca: Nature Publishing Group
DOI: 10.1038/nri.2016.136

Modulation of inflammation and disease tolerance by DNA damage response pathways

Autorzy: Ana Neves-Costa, Luis F. Moita
Opublikowane w: The FEBS Journal, Numer 284/5, 2017, Strona(/y) 680-698, ISSN 1742-464X
Wydawca: Blackwell Publishing Inc.
DOI: 10.1111/febs.13910

Deletion of iRhom2 protects against diet-induced obesity by increasing thermogenesis

Autorzy: Marina Badenes, Abdulbasit Amin, Ismael González-García, Inês Félix, Emma Burbridge, Miguel Cavadas, Francisco José Ortega, Érika de Carvalho, Pedro Faísca, Stefania Carobbio, Elsa Seixas, Dora Pedroso, Ana Neves-Costa, Luís F. Moita, José Manuel Fernández-Real, António Vidal-Puig, Ana Domingos, Miguel López, Colin Adrain
Opublikowane w: Molecular Metabolism, Numer 31, 2020, Strona(/y) 67-84, ISSN 2212-8778
Wydawca: Elsevier GmbH
DOI: 10.1016/j.molmet.2019.10.006

CXCL5-mediated recruitment of neutrophils into the peritoneal cavity of Gdf15-deficient mice protects against abdominal sepsis

Autorzy: Isa Santos, Henrique G Colaço, Ana Neves-Costa, Elsa Seixas, Tiago R Velho, Dora Pedroso, André Barros, Rui Martins, Sebastian Weiss, Didier Payen, Sebastian Weiss, Hyon-Seung Yi, Minho Shong, Luis F Moita
Opublikowane w: Proc Natl Acad Sci U S A, 2020, ISSN 1091-6490
Wydawca: Proc Natl Acad Sci U S A
DOI: 10.1101/613901

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