Common mechanisms and pathways in Stroke and Alzheimer's disease.

Rezultaty

Web application to compute and present results in a simple way for a broad audience

Online application to compute and present results of a risk assessment of AD in stroke patients in a simple way for a broad audience of clinicians and the general public

WP3 Midterm recruitment report

Overview of recruited subjects, potential recruiting problems and, if applicable, a detailed description of implemented and planned measures to compensate delays in the study subject recruitment

WP4 Report on status of posting results in the study registry(s)

Report on the status of the result posting including timelines when final posting of results is scheduled

WP3 Report on status of posting results in the study registry(s)

Report on the status of the result posting including timelines when final posting of results is scheduled

WP4 Midterm recruitment report

Overview of recruited subjects, potential recruiting problems and, if applicable, a detailed description of implemented and planned measures to compensate delays in the study subject recruitment

Report on knowledge and innovation management

Detailed report on knowledge and innovation management for CoSTREAM results and achievements

Publikacje

Circulating Metabolites Differentiate Acute Ischemic Stroke from Stroke Mimics

Autorzy: Steffen Tiedt, Stefan Brandmaier, Hanna Kollmeier, Marco Duering, Anna Artati, Jerzy Adamski, Matthias Klein, Thomas Liebig, Lesca M. Holdt, Daniel Teupser, Rui Wang‐Sattler, Edzard Schwedhelm, Christian Gieger, Martin Dichgans
Opublikowane w: Annals of Neurology, Numer 88/4, 2020, Strona(/y) 736-746, ISSN 0364-5134
Wydawca: John Wiley & Sons Inc.
DOI: 10.1002/ana.25859

Midlife vascular risk factors and risk of incident dementia: Longitudinal cohort and Mendelian randomization analyses in the UK Biobank

Autorzy: Rainer Malik, Marios K. Georgakis, Julia Neitzel, Kristiina Rannikmäe, Michael Ewers, Sudha Seshadri, Cathie L.M. Sudlow, Martin Dichgans
Opublikowane w: Alzheimer's & Dementia, 2021, ISSN 1552-5260
Wydawca: Elsevier BV
DOI: 10.1002/alz.12320

Can active life mitigate the impact of diabetes on dementia and brain aging?

Autorzy: Anna Marseglia, Alexander Darin‐Mattsson, Grégoria Kalpouzos, Giulia Grande, Laura Fratiglioni, Serhiy Dekhtyar, Weili Xu
Opublikowane w: Alzheimer's & Dementia, Numer 16/11, 2020, Strona(/y) 1534-1543, ISSN 1552-5260
Wydawca: Elsevier BV
DOI: 10.1002/alz.12142

Shared risk and protective factors between Alzheimer's disease and ischemic stroke: A population‐based longitudinal study

Autorzy: Rui Wang, Chengxuan Qiu, Christina S. Dintica, Ying Shang, Amaia Calderón Larrañaga, Hui‐Xin Wang, Weili Xu
Opublikowane w: Alzheimer's & Dementia, Numer 17/2, 2021, Strona(/y) 191-204, ISSN 1552-5260
Wydawca: Elsevier BV
DOI: 10.1002/alz.12203

Relationship between gut microbiota and circulating metabolites in population-based cohorts

Autorzy: Dina Vojinovic, Djawad Radjabzadeh, Alexander Kurilshikov, Najaf Amin, Cisca Wijmenga, Lude Franke, M. Arfan Ikram, Andre G. Uitterlinden, Alexandra Zhernakova, Jingyuan Fu, Robert Kraaij, Cornelia M. van Duijn
Opublikowane w: Nature Communications, Numer 10/1, 2019, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-019-13721-1

Herpes simplex virus 1 and the risk of dementia: a population-based study

Autorzy: Meghan J. Murphy, Lana Fani, M. Kamran Ikram, Mohsen Ghanbari, M. Arfan Ikram
Opublikowane w: Scientific Reports, Numer 11/1, 2021, ISSN 2045-2322
Wydawca: Nature Publishing Group
DOI: 10.1038/s41598-021-87963-9

Impaired olfaction is associated with cognitive decline and neurodegeneration in the brain

Autorzy: Christina S. Dintica, Anna Marseglia, Debora Rizzuto, Rui Wang, Janina Seubert, Konstantinos Arfanakis, David A. Bennett, Weili Xu
Opublikowane w: Neurology, Numer 92/7, 2019, Strona(/y) e700-e709, ISSN 0028-3878
Wydawca: Lippincott Williams & Wilkins Ltd.
DOI: 10.1212/wnl.0000000000006919

Genetically determined blood pressure, antihypertensive drug classes, and risk of stroke subtypes

Autorzy: Marios K. Georgakis, Dipender Gill, Alastair J.S. Webb, Evangelos Evangelou, Paul Elliott, Cathie L.M. Sudlow, Abbas Dehghan, Rainer Malik, Ioanna Tzoulaki, Martin Dichgans
Opublikowane w: Neurology, Numer 95/4, 2020, Strona(/y) e353-e361, ISSN 0028-3878
Wydawca: Lippincott Williams & Wilkins Ltd.
DOI: 10.1212/wnl.0000000000009814

Relationship Between Blood Pressure and Incident Cardiovascular Disease: Linear and Nonlinear Mendelian Randomization Analyses

Autorzy: Rainer Malik, Marios K. Georgakis, Marijana Vujkovic, Scott M. Damrauer, Paul Elliott, Ville Karhunen, Alice Giontella, Cristiano Fava, Jacklyn N. Hellwege, Megan M. Shuey, Todd L. Edwards, Tormod Rogne, Bjørn O. Åsvold, Ben M. Brumpton, Stephen Burgess, Martin Dichgans, Dipender Gill
Opublikowane w: Hypertension, Numer 77/6, 2021, Strona(/y) 2004-2013, ISSN 0194-911X
Wydawca: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/hypertensionaha.120.16534

RNA-Seq Identifies Circulating miR-125a-5p, miR-125b-5p, and miR-143-3p as Potential Biomarkers for Acute Ischemic Stroke

Autorzy: Steffen Tiedt, Matthias Prestel, Rainer Malik, Nicola Schieferdecker, Marco Duering, Veronika Kautzky, Ivelina Stoycheva, Julia Böck, Bernd H. Northoff, Matthias Klein, Franziska Dorn, Knut Krohn, Daniel Teupser, Arthur Liesz, Nikolaus Plesnila, Lesca Miriam Holdt, Martin Dichgans
Opublikowane w: Circulation Research, Numer 121/8, 2017, Strona(/y) 970-980, ISSN 0009-7330
Wydawca: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/circresaha.117.311572

Plasma amyloid β levels are driven by genetic variants near APOE, BACE1, APP, PSEN2 : A genome‐wide association study in over 12,000 non‐demented participants

Autorzy: Vincent Damotte, Sven J. Lee, Vincent Chouraki, Benjamin Grenier‐Boley, Jeannette Simino, Hieab Adams, Giuseppe Tosto, Charles White, Natalie Terzikhan, Carlos Cruchaga, Maria J. Knol, Shuo Li, Susanna Schraen, Megan L. Grove, Claudia Satizabal, Najaf Amin, Claudine Berr, Steven Younkin, Rebecca F. Gottesman, Luc Buée, Alexa Beiser, David S. Knopman, Andre Uitterlinden, Charles DeCarli, Jan Bre
Opublikowane w: Alzheimer's & Dementia, 2021, ISSN 1552-5260
Wydawca: Elsevier BV
DOI: 10.1002/alz.12333

Modifiable Lifestyle Factors and Risk of Stroke

Autorzy: Eric L. Harshfield, Marios K. Georgakis, Rainer Malik, Martin Dichgans, Hugh S. Markus
Opublikowane w: Stroke, Numer 52/3, 2021, Strona(/y) 931-936, ISSN 0039-2499
Wydawca: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/strokeaha.120.031710

Association of life‐course depression with the risk of dementia in late life: A nationwide twin study

Autorzy: Wenzhe Yang, Xuerui Li, Kuan‐Yu Pan, Rongrong Yang, Ruixue Song, Xiuying Qi, Nancy L. Pedersen, Weili Xu
Opublikowane w: Alzheimer's & Dementia, 2021, ISSN 1552-5260
Wydawca: Elsevier BV
DOI: 10.1002/alz.12303

The genetic architecture of the human cerebral cortex

Autorzy: KATRINA L. GRASBY, NEDA JAHANSHAD, JODIE N. PAINTER, LUCÍA COLODRO-CONDE, JANITA BRALTEN, DERREK P. HIBAR, PENELOPE A. LIND, FABRIZIO PIZZAGALLI, CHRISTOPHER R. K. CHING, MARY AGNES B. MCMAHON, NATALIA SHATOKHINA, LEO C. P. ZSEMBIK, SOPHIA I. THOMOPOULOS, ALYSSA H. ZHU, LACHLAN T. STRIKE, INGRID AGARTZ, SAUD ALHUSAINI, MARCIO A. A. ALMEIDA, DAG ALNÆS, INGE K. AMLIEN, MICAEL ANDERSSON, TYLER ARD,
Opublikowane w: Science, 2020, ISSN 0036-8075
Wydawca: American Association for the Advancement of Science
DOI: 10.1126/science.aay6690

Integration of demographics, genetics, imaging and metabolomics data to identify Alzheimer’s disease patients

Autorzy: Vincent Damotte, Guillemette Marot, Aline Meirhaeghe, Philippe Amouyel, Céline Bellenguez, Vincent Chouraki
Opublikowane w: Alzheimer's & Dementia, Numer 16/S4, 2020, ISSN 1552-5260
Wydawca: Elsevier BV
DOI: 10.1002/alz.042659

Patterns of Mitochondrial TSPO Binding in Cerebral Small Vessel Disease: An in vivo PET Study With Neuropathological Comparison

Autorzy: Paul Wright, Mattia Veronese, Ndabezinhle Mazibuko, Federico E. Turkheimer, Eugenii A. Rabiner, Clive G. Ballard, Steven C. R. Williams, Avinash Kumar Hari Narayanan, Bahiya Osrah, Ricky Williams, Tiago R. Marques, Oliver D. Howes, Federico Roncaroli, Michael J. O'Sullivan
Opublikowane w: Frontiers in Neurology, Numer 11, 2020, ISSN 1664-2295
Wydawca: Frontiers Research Foundation
DOI: 10.3389/fneur.2020.541377

Common Genetic Variation Indicates Separate Causes for Periventricular and Deep White Matter Hyperintensities

Autorzy: Nicola J. Armstrong, Karen A. Mather, Muralidharan Sargurupremraj, Maria J. Knol, Rainer Malik, Claudia L. Satizabal, Lisa R. Yanek, Wei Wen, Vilmundur G. Gudnason, Nicole D. Dueker, Lloyd T. Elliott, Edith Hofer, Joshua Bis, Neda Jahanshad, Shuo Li, Mark A. Logue, Michelle Luciano, Markus Scholz, Albert V. Smith, Stella Trompet, Dina Vojinovic, Rui Xia, Fidel Alfaro-Almagro, David Ames, Najaf Ami
Opublikowane w: Stroke, Numer 51/7, 2020, Strona(/y) 2111-2121, ISSN 0039-2499
Wydawca: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/strokeaha.119.027544

Multiomics integrative analysis identifies APOE allele-specific blood biomarkers associated to Alzheimer’s disease etiopathogenesis

Autorzy: Laura Madrid, Sonia Moreno-Grau, Shahzad Ahmad, Antonio González-Pérez, Itziar de Rojas, Rui Xia, Pamela V. Martino Adami, Pablo García-González, Luca Kleineidam, Qiong Yang, Vincent Damotte, Joshua C. Bis, Fuensanta Noguera-Perea, Céline Bellenguez, Xueqiu Jian, Juan Marín-Muñoz, Benjamin Grenier-Boley, Adela Orellana, M. Arfan Ikram, Philippe Amouyel, Claudia L. Satizabal, Luis Miguel Rea
Opublikowane w: Aging, Numer 13/7, 2021, Strona(/y) 9277-9329, ISSN 1945-4589
Wydawca: Medline
DOI: 10.18632/aging.202950

A Key Role for Subiculum-Fornix Connectivity in Recollection in Older Age

Autorzy: Naomi Hartopp, Paul Wright, Nicola J. Ray, Tavia E. Evans, Claudia Metzler-Baddeley, John P. Aggleton, Michael J. O’Sullivan
Opublikowane w: Frontiers in Systems Neuroscience, Numer 12, 2019, ISSN 1662-5137
Wydawca: Frontiers Research Foundation
DOI: 10.3389/fnsys.2018.00070

Genetic determinants of blood lipids and cerebral small vessel disease: role of high-density lipoprotein cholesterol

Autorzy: Marios K Georgakis, Rainer Malik, Christopher D Anderson, Klaus G Parhofer, Jemma C Hopewell, Martin Dichgans
Opublikowane w: Brain, Numer 143/2, 2020, Strona(/y) 597-610, ISSN 0006-8950
Wydawca: Oxford University Press
DOI: 10.1093/brain/awz413

Atrial Fibrillation Genetic Risk and Ischemic Stroke Mechanisms

Autorzy: Steven A. Lubitz, Owen E. Parsons, Christopher D. Anderson, Emelia J. Benjamin, Rainer Malik, Lu-Chen Weng, Martin Dichgans, Cathie L. Sudlow, Peter M. Rothwell, Jonathan Rosand, Patrick T. Ellinor, Hugh S. Markus, Matthew Traylor
Opublikowane w: Stroke, Numer 48/6, 2017, Strona(/y) 1451-1456, ISSN 0039-2499
Wydawca: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/strokeaha.116.016198

Association of Circulating Monocyte Chemoattractant Protein–1 Levels With Cardiovascular Mortality

Autorzy: Marios K. Georgakis, James A. de Lemos, Colby Ayers, Biqi Wang, Harry Björkbacka, Tiberiu A. Pana, Barbara Thorand, Caroline Sun, Lana Fani, Rainer Malik, Josée Dupuis, Gunnar Engström, Marju Orho-Melander, Olle Melander, S. Matthijs Boekholdt, Astrid Zierer, Mohamed A. Elhadad, Wolfgang Koenig, Christian Herder, Ron C. Hoogeveen, Maryam Kavousi, Christie M. Ballantyne, Annette Peters, Phyo K.
Opublikowane w: JAMA Cardiology, Numer 6/5, 2021, Strona(/y) 587, ISSN 2380-6583
Wydawca: JAMA
DOI: 10.1001/jamacardio.2020.5392

Deep learning‐guided joint attenuation and scatter correction in multitracer neuroimaging studies

Autorzy: Hossein Arabi, Karin Bortolin, Nathalie Ginovart, Valentina Garibotto, Habib Zaidi
Opublikowane w: Human Brain Mapping, Numer 41/13, 2020, Strona(/y) 3667-3679, ISSN 1065-9471
Wydawca: John Wiley & Sons Inc.
DOI: 10.1002/hbm.25039

Association of Circulating Metabolites in Plasma or Serum and Risk of Stroke

Autorzy: Dina Vojinovic, Marita Kalaoja, Stella Trompet, Krista Fischer, Martin J. Shipley, Shuo Li, Aki S. Havulinna, Markus Perola, Veikko Salomaa, Qiong Yang, Naveed Sattar, Pekka Jousilahti, Najaf Amin, Claudia L. Satizabal, Nele Taba, Behnam Sabayan, Ramachandran S. Vasan, M. Arfan Ikram, David J. Stott, Mika Ala-Korpela, J. Wouter Jukema, Sudha Seshadri, Johannes Kettunen, Mika Kivimaki, Tonu Esko, C
Opublikowane w: Neurology, Numer 96/8, 2021, Strona(/y) e1110-e1123, ISSN 0028-3878
Wydawca: Lippincott Williams & Wilkins Ltd.
DOI: 10.1212/wnl.0000000000011236

Dose–response relationship between genetically proxied average blood glucose levels and incident coronary heart disease in individuals without diabetes mellitus

Autorzy: Stephen Burgess, Rainer Malik, Bowen Liu, Amy M. Mason, Marios K. Georgakis, Martin Dichgans, Dipender Gill
Opublikowane w: Diabetologia, Numer 64/4, 2021, Strona(/y) 845-849, ISSN 0012-186X
Wydawca: Springer Verlag
DOI: 10.1007/s00125-020-05377-0

Genetic variants influencing elevated myeloperoxidase levels increase risk of stroke

Autorzy: Chia-Ling Phuah, Tushar Dave, Rainer Malik, Miriam R Raffeld, Alison M Ayres, Joshua N Goldstein, Anand Viswanathan, Steven M Greenberg, Jeremiasz M Jagiella, Björn M Hansen, Bo Norrving, Jordi Jimenez-Conde, Jaume Roquer, Alexander Pichler, Christian Enzinger, Joan Montaner, Israel Fernandez-Cadenas, Arne Lindgren, Agnieszka Slowik, Reinhold Schmidt, Alessandro Biffi, Natalia Rost, Carl D Langef
Opublikowane w: Brain, Numer 140/10, 2017, Strona(/y) 2663-2672, ISSN 0006-8950
Wydawca: Oxford University Press
DOI: 10.1093/brain/awx220

Genetically Predicted Blood Pressure Across the Lifespan

Autorzy: Marios K. Georgakis, Dipender Gill, Rainer Malik, Athanase D. Protogerou, Alastair J.S. Webb, Martin Dichgans
Opublikowane w: Hypertension, Numer 76/3, 2020, Strona(/y) 953-961, ISSN 0194-911X
Wydawca: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/hypertensionaha.120.15136

A high-throughput, ultrafast, and online three-phase electro-extraction method for analysis of trace level pharmaceuticals

Autorzy: Yupeng He, Paul Miggiels, Bert Wouters, Nicolas Drouin, Faisa Guled, Thomas Hankemeier, Petrus W. Lindenburg
Opublikowane w: Analytica Chimica Acta, Numer 1149, 2021, Strona(/y) 338204, ISSN 0003-2670
Wydawca: Elsevier BV
DOI: 10.1016/j.aca.2021.338204

Association of lifespan cognitive reserve indicator with the risk of mild cognitive impairment and its progression to dementia

Autorzy: Hui Xu, Rongrong Yang, Christina Dintica, Xiuying Qi, Ruixue Song, David A Bennett, Weili Xu
Opublikowane w: Alzheimer's & Dementia, Numer 16/6, 2020, Strona(/y) 873-882, ISSN 1552-5260
Wydawca: Elsevier BV
DOI: 10.1002/alz.12085

Prevalence, Severity, and Clinical Management of Brain Incidental Findings in Healthy Young Adults: MRi-Share Cross-Sectional Study

Autorzy: Aïcha Soumaré, Naka Beguedou, Alexandre Laurent, Bruno Brochet, Constance Bordes, Sandy Mournet, Emmanuel Mellet, Edwige Pereira, Clothilde Pollet, Morgane Lachaize, Marie Mougin, Ami Tsuchida, Hugues Loiseau, Thomas Tourdias, Christophe Tzourio, Bernard Mazoyer, Stéphanie Debette
Opublikowane w: Frontiers in Neurology, Numer 12, 2021, ISSN 1664-2295
Wydawca: Frontiers Research Foundation
DOI: 10.3389/fneur.2021.675244

Plasma Brain-Derived Neurotropic Factor Levels Are Associated with Aging and Smoking But Not with Future Dementia in the Rotterdam Study

Autorzy: Sara Galle, Silvan Licher, Maarten Milders, Jan Berend Deijen, Erik Scherder, Madeleine Drent, Arfan Ikram, Cornelia M. van Duijn
Opublikowane w: Journal of Alzheimer's Disease, Numer 80/3, 2021, Strona(/y) 1139-1149, ISSN 1387-2877
Wydawca: IOS Press
DOI: 10.3233/jad-200371

Cardiometabolic traits mediating the effect of education on osteoarthritis risk: a Mendelian randomization study

Autorzy: D. Gill, V. Karhunen, R. Malik, M. Dichgans, N. Sofat
Opublikowane w: Osteoarthritis and Cartilage, Numer 29/3, 2021, Strona(/y) 365-371, ISSN 1063-4584
Wydawca: W. B. Saunders Co., Ltd.
DOI: 10.1016/j.joca.2020.12.015

Circulating metabolites are associated with brain atrophy and white matter hyperintensities

Autorzy: Francisca A. Leeuw, Hata Karamujić‐Čomić, Betty M. Tijms, Carel F.W. Peeters, Maartje I. Kester, Philip Scheltens, Shahzad Ahmad, Dina Vojinovic, Hieab H.H. Adams, Thomas Hankemeier, Daniel Bos, Aad Lugt, Meike W. Vernooij, M. Arfan Ikram, Najaf Amin, Frederik Barkhof, Charlotte E. Teunissen, Cornelia M. Duijn, Wiesje M. Flier
Opublikowane w: Alzheimer's & Dementia, Numer 17/2, 2021, Strona(/y) 205-214, ISSN 1552-5260
Wydawca: Elsevier BV
DOI: 10.1002/alz.12180

The role of Apolipoprotein E epsilon4 in the association between psychosocial working conditions and dementia

Autorzy: Kuan-Yu Pan, Weili Xu, Francesca Mangialasche, Giulia Grande, Laura Fratiglioni, Hui-Xin Wang
Opublikowane w: Aging, Numer 12/4, 2020, Strona(/y) 3730-3746, ISSN 1945-4589
Wydawca: Impact Journals
DOI: 10.18632/aging.102843

Twenty-seven-year time trends in dementia incidence in Europe and the United States

Autorzy: Frank J. Wolters, Lori B. Chibnik, Reem Waziry, Roy Anderson, Claudine Berr, Alexa Beiser, Joshua C. Bis, Deborah Blacker, Daniel Bos, Carol Brayne, Jean-François Dartigues, Sirwan K.L. Darweesh, Kendra L. Davis-Plourde, Frank de Wolf, Stephanie Debette, Carole Dufouil, Myriam Fornage, Jaap Goudsmit, Leslie Grasset, Vilmundur Gudnason, Christoforos Hadjichrysanthou, Catherine Helmer, M. Arfan Ikr
Opublikowane w: Neurology, Numer 95/5, 2020, Strona(/y) e519-e531, ISSN 0028-3878
Wydawca: Lippincott Williams & Wilkins Ltd.
DOI: 10.1212/wnl.0000000000010022

Cerebral Perfusion and the Risk of Dementia

Autorzy: Frank J. Wolters, Hazel I. Zonneveld, Albert Hofman, Aad van der Lugt, Peter J. Koudstaal, Meike W. Vernooij, M. Arfan Ikram
Opublikowane w: Circulation, Numer 136/8, 2017, Strona(/y) 719-728, ISSN 0009-7322
Wydawca: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/circulationaha.117.027448

Circulating biomarkers of immunity and inflammation, risk of Alzheimer’s disease, and hippocampal volume: a Mendelian randomization study

Autorzy: Lana Fani, Marios K. Georgakis, M. Arfan Ikram, M. Kamran Ikram, Rainer Malik, Martin Dichgans
Opublikowane w: Translational Psychiatry, Numer 11/1, 2021, ISSN 2158-3188
Wydawca: Nature Publishing Group
DOI: 10.1038/s41398-021-01400-z

Mendelian randomization for studying the effects of perturbing drug targets

Autorzy: Dipender Gill, Marios K. Georgakis, Venexia M. Walker, A. Floriaan Schmidt, Apostolos Gkatzionis, Daniel F. Freitag, Chris Finan, Aroon D. Hingorani, Joanna M.M. Howson, Stephen Burgess, Daniel I. Swerdlow, George Davey Smith, Michael V. Holmes, Martin Dichgans, Robert A Scott, Jie Zheng, Bruce M. Psaty, Neil M. Davies
Opublikowane w: Wellcome Open Research, Numer 6, 2021, Strona(/y) 16, ISSN 2398-502X
Wydawca: F1000 Research
DOI: 10.12688/wellcomeopenres.16544.2

Genetic variation in PLEKHG1 is associated with white matter hyperintensities (n = 11,226)

Autorzy: Matthew Traylor, Daniel J. Tozer, Iain D. Croall, Danuta M. Lisiecka Ford, Abiodun Olubunmi Olorunda, Giorgio Boncoraglio, Martin Dichgans, Robin Lemmens, Jonathan Rosand, Natalia S. Rost, Peter M. Rothwell, Cathie L.M. Sudlow, Vincent Thijs, Loes Rutten-Jacobs, Hugh S. Markus
Opublikowane w: Neurology, Numer 92/8, 2019, Strona(/y) e749-e757, ISSN 0028-3878
Wydawca: Lippincott Williams & Wilkins Ltd.
DOI: 10.1212/WNL.0000000000006952

Associations Between Cardiovascular Risk, Structural Brain Changes, and Cognitive Decline

Autorzy: Ruixue Song, Hui Xu, Christina S. Dintica, Kuan-Yu Pan, Xiuying Qi, Aron S. Buchman, David A. Bennett, Weili Xu
Opublikowane w: Journal of the American College of Cardiology, Numer 75/20, 2020, Strona(/y) 2525-2534, ISSN 0735-1097
Wydawca: Elsevier BV
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Cerebrovascular Disease Knowledge Portal

Autorzy: Katherine M. Crawford, Cristina Gallego-Fabrega, Christina Kourkoulis, Laura Miyares, Sandro Marini, Jason Flannick, Noel P. Burtt, Marcin von Grotthuss, Benjamin Alexander, Maria C. Costanzo, Neil H. Vaishnav, Rainer Malik, Jennifer L. Hall, Michael Chong, Jonathan Rosand, Guido J. Falcone
Opublikowane w: Stroke, Numer 49/2, 2018, Strona(/y) 470-475, ISSN 0039-2499
Wydawca: Lippincott Williams & Wilkins Ltd.
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Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

Autorzy: Rainer Malik, Ganesh Chauhan, Matthew Traylor, Muralidharan Sargurupremraj, Yukinori Okada, Aniket Mishra, Loes Rutten-Jacobs, Anne-Katrin Giese, Sander W. van der Laan, Solveig Gretarsdottir, Christopher D. Anderson, Michael Chong, Hieab H. H. Adams, Tetsuro Ago, Peter Almgren, Philippe Amouyel, Hakan Ay, Traci M. Bartz, Oscar R. Benavente, Steve Bevan, Giorgio B. Boncoraglio, Robert D. Brown, Ad
Opublikowane w: Nature Genetics, Numer 50/4, 2018, Strona(/y) 524-537, ISSN 1061-4036
Wydawca: Nature Publishing Group
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Genetic Study of White Matter Integrity in UK Biobank (N=8448) and the Overlap With Stroke, Depression, and Dementia

Autorzy: Loes C.A. Rutten-Jacobs, Daniel J. Tozer, Marco Duering, Rainer Malik, Martin Dichgans, Hugh S. Markus, Matthew Traylor
Opublikowane w: Stroke, Numer 49/6, 2018, Strona(/y) 1340-1347, ISSN 0039-2499
Wydawca: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/STROKEAHA.118.020811

Subregional volumes of the hippocampus in relation to cognitive function and risk of dementia

Autorzy: Tavia E. Evans, Hieab H.H. Adams, Silvan Licher, Frank J. Wolters, Aad van der Lugt, M. Kamran Ikram, Michael J. O'Sullivan, Meike W. Vernooij, M. Arfan Ikram
Opublikowane w: NeuroImage, Numer 178, 2018, Strona(/y) 129-135, ISSN 1053-8119
Wydawca: Academic Press
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THE IMPACT OF NUTRIENT PATTERNS ON COGNITIVE DECLINE AMONG SWEDISH OLDER ADULTS: A POPULATION-BASED LONGITUDINAL STUDY

Autorzy: Federica Prinelli, Debora Rizzuto, Behnaz Shakersain, Ingegerd Johansson, Fulvio Daniele Adorni, Massimo Musicco, Laura Fratiglioni, Weili Xu
Opublikowane w: Alzheimer's & Dementia, Numer 14/7, 2018, Strona(/y) P973-P975, ISSN 1552-5260
Wydawca: Elsevier BV
DOI: 10.1016/j.jalz.2018.06.1308

The Nordic Prudent Diet Reduces Risk of Cognitive Decline in the Swedish Older Adults: A Population-Based Cohort Study

Autorzy: Behnaz Shakersain, Debora Rizzuto, Susanna Larsson, Gerd Faxén-Irving, Laura Fratiglioni, Wei-Li Xu
Opublikowane w: Nutrients, Numer 10/2, 2018, Strona(/y) 229, ISSN 2072-6643
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/nu10020229

Challenges and opportunities in stroke genetics

Autorzy: Rainer Malik, Martin Dichgans
Opublikowane w: Cardiovascular Research, 2018, ISSN 0008-6363
Wydawca: Elsevier BV
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