Leverage research EXCELLence and INNOVation potential of Instituto de Medicina Molecular (IMM) through translational biomedical research in immunity and infection.

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Re-evaluation of current state of IMM towards ERA priorities
Publications in the research field of immunity and infection of the Instituto de Medicina Molecular

A one-page statement that the task has been completed.

Acquisition of the pre-clinical molecular and imaging equipment
Organisation of thematic Workshops – first period

Organisation of thematic Workshops held during the first period

Organisation of thematic Workshops – second period

Organisation of thematic Workshops held during the second reporting period

Self-assessment after 2-year period of strategy implementation
Organisation of thematic Workshops – third period

Organisation of thematic Workshops held during the third reporting period

Launch of website
Development of the project logo/brand
Forum for overseas discussion in translational immunity and infection
Brochure and flyer development

Pubblicazioni

Description of plasmid pSM52, harbouring the gene for the Smr efflux pump, and its involvement in resistance to biocides in a meticillin-resistant Staphylococcus aureus strain

Autori: Sofia Santos Costa, Cláudia Mourato, Miguel Viveiros, José Melo-Cristino, Leonard Amaral, Isabel Couto
Pubblicato in: International Journal of Antimicrobial Agents, Numero 41/5, 2013, Pagina/e 490-492, ISSN 0924-8579
Editore: Elsevier BV
DOI: 10.1016/j.ijantimicag.2013.01.003

Functional development of γδ T cells

Autori: Immo Prinz, Bruno Silva-Santos, Daniel J. Pennington
Pubblicato in: European Journal of Immunology, Numero 43/8, 2013, Pagina/e 1988-1994, ISSN 0014-2980
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/eji.201343759

The Majority of Adult Pneumococcal Invasive Infections in Portugal Are Still Potentially Vaccine Preventable in Spite of Significant Declines of Serotypes 1 and 5

Autori: Andreia N. Horácio, Jorge Diamantino-Miranda, Sandra I. Aguiar, Mário Ramirez, José Melo-Cristino
Pubblicato in: PLoS ONE, Numero 8/9, 2013, Pagina/e e73704, ISSN 1932-6203
Editore: Public Library of Science
DOI: 10.1371/journal.pone.0073704

Memory B-cell depletion is a feature of HIV-2 infection even in the absence of detectable viremia

Autori: Rita Tendeiro, Sofia Fernandes, Russell B. Foxall, José M. Marcelino, Nuno Taveira, Rui S. Soares, António P. Baptista, Rita Cavaleiro, Perpétua Gomes, Rui M.M. Victorino, Ana E. Sousa
Pubblicato in: AIDS, Numero 26/13, 2012, Pagina/e 1607-1617, ISSN 0269-9370
Editore: Lippincott Williams & Wilkins Ltd.
DOI: 10.1097/QAD.0b013e3283568849

How Many Sputum Culture Results Do We Need To Monitor Multidrug-Resistant-Tuberculosis (MDR-TB) Patients during Treatment?

Autori: S. Janssen, X. Padanilam, R. Louw, R. Mahanyele, G. Coetzee, T. Hanscheid, T. Leenstra, M. P. Grobusch
Pubblicato in: Journal of Clinical Microbiology, Numero 51/2, 2013, Pagina/e 644-646, ISSN 0095-1137
Editore: American Society for Microbiology
DOI: 10.1128/JCM.02837-12

Recent thymic emigrants are the preferential precursors of regulatory T cells differentiated in the periphery

Autori: R. S. Paiva, A. C. Lino, M.-L. Bergman, I. Caramalho, A. E. Sousa, S. Zelenay, J. Demengeot
Pubblicato in: Proceedings of the National Academy of Sciences, Numero 110/16, 2013, Pagina/e 6494-6499, ISSN 0027-8424
Editore: National Academy of Sciences
DOI: 10.1073/pnas.1221955110

Controlling the pandemic during the SARS-CoV-2 vaccination rollout

Autori: João Viana, Christiaan H. van Dorp, Ana Nunes, Manuel C. Gomes, Michiel van Boven, Mirjam E. Kretzschmar, Marc Veldhoen, Ganna Rozhnova
Pubblicato in: Nature Communications, Numero 12/1, 2021, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-021-23938-8

Structural Optimization of Quinolon-4(1 H )-imines as Dual-Stage Antimalarials: Toward Increased Potency and Metabolic Stability

Autori: Ana S. Ressurreição, Daniel Gonçalves, Ana R. Sitoe, Inês S. Albuquerque, Jiri Gut, Ana Góis, Lídia M. Gonçalves, Maria R. Bronze, Thomas Hanscheid, Giancarlo A. Biagini, Philip J. Rosenthal, Miguel Prudêncio, Paul O’Neill, Maria M. Mota, Francisca Lopes, Rui Moreira
Pubblicato in: Journal of Medicinal Chemistry, Numero 56/19, 2013, Pagina/e 7679-7690, ISSN 0022-2623
Editore: American Chemical Society
DOI: 10.1021/jm4011466

Monocyte activation is a feature of common variable immunodeficiency irrespective of plasma lipopolysaccharide levels

Autori: R. R. Barbosa, S. P. Silva, S. L. Silva, R. Tendeiro, A. C. Melo, E. Pedro, M. P. Barbosa, M. C. P. Santos, R. M. M. Victorino, A. E. Sousa
Pubblicato in: Clinical & Experimental Immunology, Numero 169/3, 2012, Pagina/e 263-272, ISSN 0009-9104
Editore: Blackwell Publishing Inc.
DOI: 10.1111/j.1365-2249.2012.04620.x

Th17 Cells Require You to Chew before You Swallow

Autori: Marc Veldhoen
Pubblicato in: Immunity, Numero 46/1, 2017, Pagina/e 8-10, ISSN 1074-7613
Editore: Cell Press
DOI: 10.1016/j.immuni.2016.12.016

The fate of CD4+ T cells under tolerance-inducing stimulation: a modeling perspective

Autori: Marta Caridade, Vanessa G Oliveira, Ana Agua-Doce, Luis Graca, Ruy M Ribeiro
Pubblicato in: Immunology and Cell Biology, Numero 91/10, 2013, Pagina/e 652-660, ISSN 0818-9641
Editore: Blackwell Publishing Inc.
DOI: 10.1038/icb.2013.63

Export of the pneumococcal phage SV1 lysin requires choline-containing teichoic acids and is holin-independent

Autori: Maria João Frias, José Melo-Cristino, Mário Ramirez
Pubblicato in: Molecular Microbiology, Numero 87/2, 2013, Pagina/e 430-445, ISSN 0950-382X
Editore: Blackwell Publishing Inc.
DOI: 10.1111/mmi.12108

Enteric Mucosa Integrity in the Presence of a Preserved Innate Interleukin 22 Compartment in HIV Type 1-Treated Individuals

Autori: S. M. Fernandes, A. R. Pires, C. Ferreira, R. B. Foxall, J. Rino, C. Santos, L. Correia, J. Pocas, H. Veiga-Fernandes, A. E. Sousa
Pubblicato in: Journal of Infectious Diseases, Numero 210/4, 2014, Pagina/e 630-640, ISSN 0022-1899
Editore: University of Chicago Press
DOI: 10.1093/infdis/jiu126

RET/GFRα Signals Are Dispensable for Thymic T Cell Development In Vivo

Autori: Afonso Rocha Martins Almeida, Sílvia Arroz-Madeira, Diogo Fonseca-Pereira, Hélder Ribeiro, Reena Lasrado, Vassilis Pachnis, Henrique Veiga-Fernandes
Pubblicato in: PLoS ONE, Numero 7/12, 2012, Pagina/e e52949, ISSN 1932-6203
Editore: Public Library of Science
DOI: 10.1371/journal.pone.0052949

In Vitro Alterations Do Not Reflect a Requirement for Host Cell Cycle Progression during Plasmodium Liver Stage Infection

Autori: Kirsten K. Hanson, Sandra March, Shengyong Ng, Sangeeta N. Bhatia, Maria M. Mota
Pubblicato in: Eukaryotic Cell, Numero 14/1, 2014, Pagina/e 96-103, ISSN 1535-9778
Editore: American Society for Microbiology
DOI: 10.1128/EC.00166-14

Evaluation of a Novel Magneto-Optical Method for the Detection of Malaria Parasites

Autori: Ágnes Orbán, Ádám Butykai, András Molnár, Zsófia Pröhle, Gergö Fülöp, Tivadar Zelles, Wasan Forsyth, Danika Hill, Ivo Müller, Louis Schofield, Maria Rebelo, Thomas Hänscheid, Stephan Karl, István Kézsmárki
Pubblicato in: PLoS ONE, Numero 9/5, 2014, Pagina/e e96981, ISSN 1932-6203
Editore: Public Library of Science
DOI: 10.1371/journal.pone.0096981

Recruitment of γδ T lymphocytes to tumors

Autori: Telma Lança, Bruno Silva-Santos
Pubblicato in: OncoImmunology, Numero 2/8, 2013, Pagina/e e25461, ISSN 2162-4011
Editore: Landes Bioscience
DOI: 10.4161/onci.25461

Superantigen gene complement of Streptococcus pyogenes—relationship with other typing methods and short-term stability

Autori: A. Friães, F. R. Pinto, C. Silva-Costa, M. Ramirez, J. Melo-Cristino
Pubblicato in: European Journal of Clinical Microbiology & Infectious Diseases, Numero 32/1, 2013, Pagina/e 115-125, ISSN 0934-9723
Editore: Springer Verlag
DOI: 10.1007/s10096-012-1726-3

Seroprevalence of anti‐SARS‐CoV‐2 antibodies in COVID‐19 patients and healthy volunteers up to 6 months post disease onset

Autori: Patrícia Figueiredo‐Campos, Birte Blankenhaus, Catarina Mota, Andreia Gomes, Marta Serrano, Silvia Ariotti, Catarina Costa, Helena Nunes‐Cabaço, António M. Mendes, Pedro Gaspar, M. Conceição Pereira‐Santos, Fabiana Rodrigues, Jorge Condeço, M. Antonia Escoval, Matilde Santos, Mario Ramirez, José Melo‐Cristino, J. Pedro Simas, Eugenia Vasconcelos, Ângela Afonso, Marc Veldhoen
Pubblicato in: European Journal of Immunology, Numero 50/12, 2020, Pagina/e 2025-2040, ISSN 0014-2980
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/eji.202048970

Chicago 2014 – 30years of γδ T cells

Autori: Marc Bonneville, Zheng W. Chen, Julie Déchanet-Merville, Matthias Eberl, Jean Jacques Fournié, Julie M. Jameson, Richard D. Lopez, Massimo Massaia, Bruno Silva-Santos
Pubblicato in: Cellular Immunology, Numero 296/1, 2015, Pagina/e 3-9, ISSN 0008-8749
Editore: Academic Press
DOI: 10.1016/j.cellimm.2014.11.001

3-hydroxy-L-kynurenamine is an immunomodulatory biogenic amine

Autori: Cristina C. Clement, Angelo D’Alessandro, Sangeetha Thangaswamy, Samantha Chalmers, Raquel Furtado, Sheila Spada, Giada Mondanelli, Federica Ianni, Sarah Gehrke, Marco Gargaro, Giorgia Manni, Luisa Carlota Lopez Cara, Peter Runge, Wanxia Li Tsai, Sinem Karaman, Jorge Arasa, Ruben Fernandez-Rodriguez, Amanda Beck, Antonio Macchiarulo, Massimo Gadina, Cornelia Halin, Francesca Fallarino, Mihaela S
Pubblicato in: Nature Communications, Numero 12/1, 2021, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-021-24785-3

Haemozoin detection in infected erythrocytes for Plasmodium falciparum malaria diagnosis—Prospects and limitations

Autori: Maria Rebelo, Howard M. Shapiro, Teresa Amaral, José Melo-Cristino, Thomas Hänscheid
Pubblicato in: Acta Tropica, Numero 123/1, 2012, Pagina/e 58-61, ISSN 0001-706X
Editore: Elsevier BV
DOI: 10.1016/j.actatropica.2012.03.005

Infection by Plasmodium changes shape and stiffness of hepatic cells

Autori: Peter Eaton, Vanessa Zuzarte-Luis, Maria M. Mota, Nuno C. Santos, Miguel Prudêncio
Pubblicato in: Nanomedicine: Nanotechnology, Biology and Medicine, Numero 8/1, 2012, Pagina/e 17-19, ISSN 1549-9634
Editore: Elsevier BV
DOI: 10.1016/j.nano.2011.10.004

Quinolin-4(1 H )-imines are Potent Antiplasmodial Drugs Targeting the Liver Stage of Malaria

Autori: Tiago Rodrigues, Filipa P. da Cruz, Maria J. Lafuente-Monasterio, Daniel Gonçalves, Ana S. Ressurreição, Ana R. Sitoe, Maria R. Bronze, Jiri Gut, Gisbert Schneider, Maria M. Mota, Philip J. Rosenthal, Miguel Prudêncio, Francisco-Javier Gamo, Francisca Lopes, Rui Moreira
Pubblicato in: Journal of Medicinal Chemistry, Numero 56/11, 2013, Pagina/e 4811-4815, ISSN 0022-2623
Editore: American Chemical Society
DOI: 10.1021/jm400246e

Insight into lymphoid tissue morphogenesis

Autori: Mark Coles, Henrique Veiga-Fernandes
Pubblicato in: Immunology Letters, Numero 156/1-2, 2013, Pagina/e 46-53, ISSN 0165-2478
Editore: Elsevier BV
DOI: 10.1016/j.imlet.2013.08.001

Crystal Structure of the Gamma-2 Herpesvirus LANA DNA Binding Domain Identifies Charged Surface Residues Which Impact Viral Latency

Autori: Bruno Correia, Sofia A. Cerqueira, Chantal Beauchemin, Marta Pires de Miranda, Shijun Li, Rajesh Ponnusamy, LÃ©nia Rodrigues, Thomas R. Schneider, Maria A. Carrondo, Kenneth M. Kaye, J. Pedro Simas, Colin E. McVey
Pubblicato in: PLoS Pathogens, Numero 9/10, 2013, Pagina/e e1003673, ISSN 1553-7366
Editore: Public Library of Science
DOI: 10.1371/journal.ppat.1003673

Smarcad1 mediates microbiota-induced inflammation in mouse and coordinates gene expression in the intestinal epithelium

Autori: Juri Kazakevych, Jérémy Denizot, Anke Liebert, Mariana Portovedo, Mia Mosavie, Payal Jain, Claudia Stellato, Claire Fraser, Renan Oliveira Corrêa, Marina Célestine, Raphaël Mattiuz, Hanneke Okkenhaug, J. Ross Miller, Marco Aurélio Ramirez Vinolo, Marc Veldhoen, Patrick Varga-Weisz
Pubblicato in: Genome Biology, Numero 21/1, 2020, ISSN 1474-760X
Editore: BMC
DOI: 10.1186/s13059-020-01976-7

Torins are potent antimalarials that block replenishment of Plasmodium liver stage parasitophorous vacuole membrane proteins

Autori: K. K. Hanson, A. S. Ressurreicao, K. Buchholz, M. Prudencio, J. D. Herman-Ornelas, M. Rebelo, W. L. Beatty, D. F. Wirth, T. Hanscheid, R. Moreira, M. Marti, M. M. Mota
Pubblicato in: Proceedings of the National Academy of Sciences, Numero 110/30, 2013, Pagina/e E2838-E2847, ISSN 0027-8424
Editore: National Academy of Sciences
DOI: 10.1073/pnas.1306097110

Drug Screen Targeted at Plasmodium Liver Stages Identifies a Potent Multistage Antimalarial Drug

Autori: F. P. da Cruz, C. Martin, K. Buchholz, M. J. Lafuente-Monasterio, T. Rodrigues, B. Sonnichsen, R. Moreira, F.-J. Gamo, M. Marti, M. M. Mota, M. Hannus, M. Prudencio
Pubblicato in: Journal of Infectious Diseases, Numero 205/8, 2012, Pagina/e 1278-1286, ISSN 0022-1899
Editore: University of Chicago Press
DOI: 10.1093/infdis/jis184

Group A streptococci clones associated with invasive infections and pharyngitis in Portugal present differences in emm types, superantigen gene content and antimicrobial resistance

Autori: Ana Friães, Francisco R Pinto, Catarina Silva-Costa, Mario Ramirez, José Melo-Cristino
Pubblicato in: BMC Microbiology, Numero 12/1, 2012, Pagina/e 280, ISSN 1471-2180
Editore: BioMed Central
DOI: 10.1186/1471-2180-12-280

Molecular Mechanisms of Differentiation of Murine Pro-Inflammatory γδ T Cell Subsets

Autori: Karine Serre, Bruno Silva-Santos
Pubblicato in: Frontiers in Immunology, Numero 4, 2013, ISSN 1664-3224
Editore: Frontiers Editorial Office
DOI: 10.3389/fimmu.2013.00431

Gold nanoparticle-based fluorescence immunoassay for malaria antigen detection

Autori: Bassem S. S. Guirgis, Cláudia Sá e Cunha, Inês Gomes, Miguel Cavadas, Isabel Silva, Gonçalo Doria, Gregory L. Blatch, Pedro V. Baptista, Eulália Pereira, Hassan M. E. Azzazy, Maria M. Mota, Miguel Prudêncio, Ricardo Franco
Pubblicato in: Analytical and Bioanalytical Chemistry, Numero 402/3, 2012, Pagina/e 1019-1027, ISSN 1618-2642
Editore: Springer Verlag
DOI: 10.1007/s00216-011-5489-y

Defining Immune Engagement Thresholds for In Vivo Control of Virus-Driven Lymphoproliferation

Autori: Cristina Godinho-Silva, Sofia Marques, Diana Fontinha, Henrique Veiga-Fernandes, Philip G. Stevenson, J. Pedro Simas
Pubblicato in: PLoS Pathogens, Numero 10/6, 2014, Pagina/e e1004220, ISSN 1553-7366
Editore: Public Library of Science
DOI: 10.1371/journal.ppat.1004220

iNKT Cells: Innate Lymphocytes with a Diverse Response

Autori: Marta Monteiro, Luis Graca
Pubblicato in: Critical Reviews in Immunology, Numero 34/1, 2014, Pagina/e 81-90, ISSN 1040-8401
Editore: Begell House
DOI: 10.1615/CritRevImmunol.2014010088

N- Cinnamoylation of Antimalarial Classics: Quinacrine Analogues with Decreased Toxicity and Dual-Stage Activity

Autori: Ana Gomes, Bianca Pérez, Inês Albuquerque, Marta Machado, Miguel Prudêncio, Fátima Nogueira, Cátia Teixeira, Paula Gomes
Pubblicato in: ChemMedChem, Numero 9/2, 2014, Pagina/e 305-310, ISSN 1860-7179
Editore: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/cmdc.201300459

A Microscale Human Liver Platform that Supports the Hepatic Stages of Plasmodium falciparum and vivax

Autori: Sandra March, Shengyong Ng, Soundarapandian Velmurugan, Ani Galstian, Jing Shan, David J. Logan, Anne E. Carpenter, David Thomas, B. Kim Lee Sim, Maria M. Mota, Stephen L. Hoffman, Sangeeta N. Bhatia
Pubblicato in: Cell Host & Microbe, Numero 14/1, 2013, Pagina/e 104-115, ISSN 1931-3128
Editore: Cell Press
DOI: 10.1016/j.chom.2013.06.005

γδ T-cell conference 2012: Close encounters for the fifth time

Autori: Bruno Silva-Santos, Wolfgang W. A. Schamel, Paul Fisch, Matthias Eberl
Pubblicato in: European Journal of Immunology, Numero 42/12, 2012, Pagina/e 3101-3105, ISSN 0014-2980
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/eji.201270101

TACI deficiency enhances antibody avidity and clearance of an intestinal pathogen

Autori: Shoichiro Tsuji, Lucas Stein, Nobuhiko Kamada, Gabriel Nuñez, Richard Bram, Bruce A. Vallance, Ana E. Sousa, Jeffrey L. Platt, Marilia Cascalho
Pubblicato in: Journal of Clinical Investigation, Numero 124/11, 2014, Pagina/e 4857-4866, ISSN 0021-9738
Editore: American Society for Clinical Investigation
DOI: 10.1172/JCI74428

A Novel Carbon Monoxide-Releasing Molecule Fully Protects Mice from Severe Malaria

Autori: A. C. Pena, N. Penacho, L. Mancio-Silva, R. Neres, J. D. Seixas, A. C. Fernandes, C. C. Romao, M. M. Mota, G. J. L. Bernardes, A. Pamplona
Pubblicato in: Antimicrobial Agents and Chemotherapy, Numero 56/3, 2012, Pagina/e 1281-1290, ISSN 0066-4804
Editore: American Society for Microbiology
DOI: 10.1128/AAC.05571-11

Monocyte and Myeloid Dendritic Cell Activation Occurs Throughout HIV Type 2 Infection, an Attenuated Form of HIV Disease

Autori: R. Cavaleiro, R. Tendeiro, R. B. Foxall, R. S. Soares, A. P. Baptista, P. Gomes, E. Valadas, R. M. M. Victorino, A. E. Sousa
Pubblicato in: Journal of Infectious Diseases, Numero 207/11, 2013, Pagina/e 1730-1742, ISSN 0022-1899
Editore: University of Chicago Press
DOI: 10.1093/infdis/jit085

Loss of Phosphatidylinositol 3-Kinase Activity in Regulatory T Cells Leads to Neuronal Inflammation

Autori: Anne-Katrien Stark, Elizabeth C. M. Davenport, Daniel T. Patton, Cheryl L. Scudamore, Bart Vanhaesebroeck, Marc Veldhoen, Oliver A. Garden, Klaus Okkenhaug
Pubblicato in: The Journal of Immunology, Numero 205/1, 2020, Pagina/e 78-89, ISSN 0022-1767
Editore: American Association of Immunologists
DOI: 10.4049/jimmunol.2000043

Role of Src Homology Domain Binding in Signaling Complexes Assembled by the Murid -Herpesvirus M2 Protein

Autori: M. Pires de Miranda, F. B. Lopes, C. E. McVey, X. R. Bustelo, J. P. Simas
Pubblicato in: Journal of Biological Chemistry, Numero 288/6, 2013, Pagina/e 3858-3870, ISSN 0021-9258
Editore: American Society for Biochemistry and Molecular Biology Inc.
DOI: 10.1074/jbc.M112.439810

Extensive Dissemination of Methicillin-Resistant Staphylococcus aureus (MRSA) between the Hospital and the Community in a Country with a High Prevalence of Nosocomial MRSA

Autori: Diana Espadinha, Nuno A. Faria, Maria Miragaia, Luís Marques Lito, José Melo-Cristino, Hermínia de Lencastre
Pubblicato in: PLoS ONE, Numero 8/4, 2013, Pagina/e e59960, ISSN 1932-6203
Editore: Public Library of Science
DOI: 10.1371/journal.pone.0059960

Use of the 13-valent conjugate vaccine has the potential to eliminate pilus carrying isolates as causes of invasive pneumococcal disease

Autori: Sandra I. Aguiar, José Melo-Cristino, Mário Ramirez
Pubblicato in: Vaccine, Numero 30/37, 2012, Pagina/e 5487-5490, ISSN 0264-410X
Editore: Elsevier BV
DOI: 10.1016/j.vaccine.2012.06.062

Bacillus invictae sp. nov., isolated from a health product

Autori: R. Branquinho, C. Sousa, H. Osorio, L. Meirinhos-Soares, J. Lopes, J. A. Carrico, H.-J. Busse, A. Abdulmawjood, G. Klein, P. Kampfer, M. E. Pintado, L. V. Peixe
Pubblicato in: INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY, Numero 64/Pt 11, 2014, Pagina/e 3867-3876, ISSN 1466-5026
Editore: Society for General Microbiology
DOI: 10.1099/ijs.0.067850-0

Severe COVID-19 Recovery Is Associated with Timely Acquisition of a Myeloid Cell Immune-Regulatory Phenotype

Autori: Amelia C. Trombetta, Guilherme B. Farias, André M. C. Gomes, Ana Godinho-Santos, Pedro Rosmaninho, Carolina M. Conceição, Joel Laia, Diana F. Santos, Afonso R. M. Almeida, Catarina Mota, Andreia Gomes, Marta Serrano, Marc Veldhoen, Ana E. Sousa, Susana M. Fernandes
Pubblicato in: Frontiers in Immunology, Numero 12, 2021, ISSN 1664-3224
Editore: FRONTIERS MEDIA SA
DOI: 10.3389/fimmu.2021.691725

T Cell Apoptosis and Induction of Foxp3+ Regulatory T Cells Underlie the Therapeutic Efficacy of CD4 Blockade in Experimental Autoimmune Encephalomyelitis

Autori: J. Duarte, N. Carrie, V. G. Oliveira, C. Almeida, A. Agua-Doce, L. Rodrigues, J. P. Simas, L. T. Mars, L. Graca
Pubblicato in: The Journal of Immunology, Numero 189/4, 2012, Pagina/e 1680-1688, ISSN 0022-1767
Editore: American Association of Immunologists
DOI: 10.4049/jimmunol.1201269

Maternal retinoids control type 3 innate lymphoid cells and set the offspring immunity

Autori: Serge A. van de Pavert, Manuela Ferreira, Rita G. Domingues, Hélder Ribeiro, Rosalie Molenaar, Lara Moreira-Santos, Francisca F. Almeida, Sales Ibiza, Inês Barbosa, Gera Goverse, Carlos Labão-Almeida, Cristina Godinho-Silva, Tanja Konijn, Dennis Schooneman, Tom O’Toole, Mark R. Mizee, Yasmin Habani, Esther Haak, Fabio R. Santori, Dan R. Littman, Stefan Schulte-Merker, Elaine Dzierzak, J. Pedro Simas, Reina E. Mebius, Henrique Veiga-Fernandes
Pubblicato in: Nature, Numero 508/7494, 2014, Pagina/e 123-127, ISSN 0028-0836
Editore: Nature Publishing Group
DOI: 10.1038/nature13158

PCR based differentiation between Streptococcus dysgalactiae subsp. equisimilis strains isolated from humans and horses

Autori: S. Preziuso, M.D. Pinho, A.R. Attili, J. Melo-Cristino, E. Acke, A.C. Midwinter, V. Cuteri, M. Ramirez
Pubblicato in: Comparative Immunology, Microbiology and Infectious Diseases, Numero 37/3, 2014, Pagina/e 169-172, ISSN 0147-9571
Editore: Pergamon Press Ltd.
DOI: 10.1016/j.cimid.2014.04.001

Preserved CD4 T-cell telomere length during long-lasting HIV-2 infection

Autori: Rita Tendeiro, Adriana S. Albuquerque, Russell B. Foxall, Rita Cavaleiro, Rui S. Soares, António P. Baptista, Maria V.D. Soares, Perpétua Gomes, Ana E. Sousa
Pubblicato in: AIDS, Numero 27/2, 2013, Pagina/e 289-292, ISSN 0269-9370
Editore: Lippincott Williams & Wilkins Ltd.
DOI: 10.1097/QAD.0b013e32835ab234

Murine Gammaherpesvirus 68 LANA Acts on Terminal Repeat DNA To Mediate Episome Persistence

Autori: A. C. Habison, C. Beauchemin, J. P. Simas, E. J. Usherwood, K. M. Kaye
Pubblicato in: Journal of Virology, Numero 86/21, 2012, Pagina/e 11863-11876, ISSN 0022-538X
Editore: American Society for Microbiology
DOI: 10.1128/JVI.01656-12

The Emerging Protumor Role of T Lymphocytes: Implications for Cancer Immunotherapy

Autori: M. Rei, D. J. Pennington, B. Silva-Santos
Pubblicato in: Cancer Research, Numero 75/5, 2015, Pagina/e 798-802, ISSN 0008-5472
Editore: American Association for Cancer Research
DOI: 10.1158/0008-5472.CAN-14-3228

Protective Role of the Inflammatory CCR2/CCL2 Chemokine Pathway through Recruitment of Type 1 Cytotoxic T Lymphocytes to Tumor Beds

Autori: T. Lanca, M. F. Costa, N. Goncalves-Sousa, M. Rei, A. R. Grosso, C. Penido, B. Silva-Santos
Pubblicato in: The Journal of Immunology, Numero 190/12, 2013, Pagina/e 6673-6680, ISSN 0022-1767
Editore: American Association of Immunologists
DOI: 10.4049/jimmunol.1300434

Feeding immunity: skepticism, delicacies and delights

Autori: Marc Veldhoen, Henrique Veiga-Fernandes
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In vivo delivery of peptides and Toll-like receptor ligands by mannose-functionalized polymeric nanoparticles induces prophylactic and therapeutic anti-tumor immune responses in a melanoma model

Autori: Joana M. Silva, Eva Zupancic, Gaëlle Vandermeulen, Vanessa G. Oliveira, Ana Salgado, Mafalda Videira, Manuela Gaspar, Luis Graca, Véronique Préat, Helena F. Florindo
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Decreasing incidence and changes in serotype distribution of invasive pneumococcal disease in persons aged under 18 years since introduction of 10-valent and 13-valent conjugate vaccines in Portugal, July 2008 to June 2012

Autori: S I Aguiar, M J Brito, A N Horácio, J P Lopes, M Ramirez, J Melo-Cristino
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Type 1 Treg cells promote the generation of CD8+ tissue-resident memory T cells

Autori: Cristina Ferreira, Leandro Barros, Marta Baptista, Birte Blankenhaus, André Barros, Patrícia Figueiredo-Campos, Špela Konjar, Alexandra Lainé, Nadine Kamenjarin, Ana Stojanovic, Adelheid Cerwenka, Hans C. Probst, Julien C. Marie, Marc Veldhoen
Pubblicato in: Nature Immunology, Numero 21/7, 2020, Pagina/e 766-776, ISSN 1529-2908
Editore: Nature Publishing Group
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Dominance of Serotype Ia among Group B Streptococci Causing Invasive Infections in Nonpregnant Adults in Portugal

Autori: E. R. Martins, J. Melo-Cristino, M. Ramirez
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Massive hypereosinophilia and vasculitis associated with major expansion of interleukin-5-producing CD8+ T cells in HIV-1 infection

Autori: Inês Jorge, Beatriz Amaral, Luis M.S.R. Soares-Almeida, Russell B. Foxall, Rita Tendeiro, João M. Santos, Ana E. Sousa, Rui M.M. Victorino
Pubblicato in: AIDS, Numero 28/7, 2014, Pagina/e 1075-1077, ISSN 0269-9370
Editore: Lippincott Williams & Wilkins Ltd.
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Pulmonary paracoccidioidomycosis in AhR deficient hosts is severe and associated with defective Treg and Th22 responses

Autori: Eliseu Frank de Araújo, Nycolas Willian Preite, Marc Veldhoen, Flávio Vieira Loures, Vera Lúcia Garcia Calich
Pubblicato in: Scientific Reports, Numero 10/1, 2020, ISSN 2045-2322
Editore: Nature Publishing Group
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Flavones as isosteres of 4(1H)-quinolones: Discovery of ligand efficient and dual stage antimalarial lead compounds

Autori: Tiago Rodrigues, Ana S. Ressurreição, Filipa P. da Cruz, Inês S. Albuquerque, Jiri Gut, Marta P. Carrasco, Daniel Gonçalves, Rita C. Guedes, Daniel J.V.A. dos Santos, Maria M. Mota, Philip J. Rosenthal, Rui Moreira, Miguel Prudêncio, Francisca Lopes
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Innate recognition of malarial parasites by mammalian hosts

Autori: Peter Liehl, Maria M. Mota
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Editore: Elsevier BV
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Long-Term Immune Reconstitution of Naive and Memory T Cell Pools after Haploidentical Hematopoietic Stem Cell Transplantation

Autori: Rita I. Azevedo, Maria V.D. Soares, Adriana S. Albuquerque, Rita Tendeiro, Rui S. Soares, Miguel Martins, Dário Ligeiro, Rui M.M. Victorino, João F. Lacerda, Ana E. Sousa
Pubblicato in: Biology of Blood and Marrow Transplantation, Numero 19/5, 2013, Pagina/e 703-712, ISSN 1083-8791
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Assessment of Dual Life Stage Antiplasmodial Activity of British Seaweeds

Autori: Jasmine Spavieri, Andrea Allmendinger, Marcel Kaiser, Maurice Itoe, Gerald Blunden, Maria Mota, Deniz Tasdemir
Pubblicato in: Marine Drugs, Numero 11/10, 2013, Pagina/e 4019-4034, ISSN 1660-3397
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
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Multilocus Sequence Analysis of Streptococcus canis Confirms the Zoonotic Origin of Human Infections and Reveals Genetic Exchange with Streptococcus dysgalactiae subsp. equisimilis

Autori: M. D. Pinho, S. C. Matos, C. Pomba, A. Lubke-Becker, L. H. Wieler, S. Preziuso, J. Melo-Cristino, M. Ramirez
Pubblicato in: Journal of Clinical Microbiology, Numero 51/4, 2013, Pagina/e 1099-1109, ISSN 0095-1137
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Humoral Immune Response of SARS‐CoV ‐2–Infected Patients with Cancer: Influencing Factors and Mechanisms

Autori: Miguel Esperança‐Martins, Lisa Gonçalves, Inês Soares‐Pinho, Andreia Gomes, Marta Serrano, Birte Blankenhaus, Patrícia Figueiredo‐Campos, Ana Catarina‐Marques, Ana Castro‐Barbosa, Ana Cardoso, Pedro Antunes‐Meireles, Henrique Atalaia‐Barbacena, Pedro Gaspar, Patrícia Howell‐Monteiro, António Pais‐de‐Lacerda, Catarina Mota, Marc Veldhoen
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CD8+ T Cells from Mice Transnuclear for a TCR that Recognizes a Single H-2Kb-Restricted MHV68 Epitope Derived from gB-ORF8 Help Control Infection

Autori: Sharvan Sehrawat, Oktay Kirak, Paul-Albert Koenig, Marisa K. Isaacson, Sofia Marques, Gunes Bozkurt, J. Pedro Simas, Rudolph Jaenisch, Hidde L. Ploegh
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Editore: Cell Press
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Thymic HIV-2 Infection Uncovers Posttranscriptional Control of Viral Replication in Human Thymocytes

Autori: Helena Nunes-Cabaço, Paula Matoso, Russell B. Foxall, Rita Tendeiro, Ana R. Pires, Tânia Carvalho, Ana I. Pinheiro, Rui S. Soares, Ana E. Sousa
Pubblicato in: Journal of Virology, Numero 89/4, 2015, Pagina/e 2201-2208, ISSN 0022-538X
Editore: American Society for Microbiology
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Tuberculosis with malaria or HIV co-infection in a large hospital in Luanda, Angola

Autori: Emília Valadas, Augusto Gomes,Ana Sutre, Sara Brilha, Afonso Wete, Thomas Hänscheid, Francisco Antunes
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Repairing thymic function

Autori: Helena Nunes-Cabaço, Ana E. Sousa
Pubblicato in: Current Opinion in Organ Transplantation, 2013, Pagina/e 1, ISSN 1087-2418
Editore: Lippincott Williams & Wilkins Ltd.
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Murine CD27(-) V 6(+) T cells producing IL-17A promote ovarian cancer growth via mobilization of protumor small peritoneal macrophages

Autori: M. Rei, N. Goncalves-Sousa, T. Lanca, R. G. Thompson, S. Mensurado, F. R. Balkwill, H. Kulbe, D. J. Pennington, B. Silva-Santos
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Editore: National Academy of Sciences
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Microbiota derived short chain fatty acids promote histone crotonylation in the colon through histone deacetylases

Autori: Rachel Fellows, Jérémy Denizot, Claudia Stellato, Alessandro Cuomo, Payal Jain, Elena Stoyanova, Szabina Balázsi, Zoltán Hajnády, Anke Liebert, Juri Kazakevych, Hector Blackburn, Renan Oliveira Corrêa, José Luís Fachi, Fabio Takeo Sato, Willian R. Ribeiro, Caroline Marcantonio Ferreira, Hélène Perée, Mariangela Spagnuolo, Raphaël Mattiuz, Csaba Matolcsi, Joana Guedes, Jonathan Clark, M
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Point-of-care tests: where is the point?

Autori: Thomas Hänscheid, Maria Rebelo, Martin P Grobusch
Pubblicato in: The Lancet Infectious Diseases, Numero 14/10, 2014, Pagina/e 922, ISSN 1473-3099
Editore: The Lancet Publishing Group
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Gut Bacterial Metabolite Urolithin A (UA) Mitigates Ca2+ Entry in T Cells by Regulating miR-10a-5p

Autori: Shaqiu Zhang, Tamer Al-Maghout, Hang Cao, Lisann Pelzl, Madhuri S. Salker, Marc Veldhoen, Anchun Cheng, Florian Lang, Yogesh Singh
Pubblicato in: Frontiers in Immunology, Numero 10, 2019, ISSN 1664-3224
Editore: FRONTIERS MEDIA SA
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Delta-like 1-Mediated Notch Signaling Enhances the In Vitro Conversion of Human Memory CD4 T Cells into FOXP3-Expressing Regulatory T Cells

Autori: C. Mota, V. Nunes-Silva, A. R. Pires, P. Matoso, R. M. M. Victorino, A. E. Sousa, I. Caramalho
Pubblicato in: The Journal of Immunology, Numero 193/12, 2014, Pagina/e 5854-5862, ISSN 0022-1767
Editore: American Association of Immunologists
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Dual-stage triterpenoids from an African medicinal plant targeting the malaria parasite

Autori: Cátia Ramalhete, Filipa P. da Cruz, Silva Mulhovo, Inês J. Sousa, Miguel X. Fernandes, Miguel Prudêncio, Maria-José U. Ferreira
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First case of infection with vancomycin-resistant Staphylococcus aureus in Europe

Autori: José Melo-Cristino, Cristina Resina, Viviana Manuel, Luís Lito, Mário Ramirez
Pubblicato in: The Lancet, Numero 382/9888, 2013, Pagina/e 205, ISSN 0140-6736
Editore: The Lancet Publishing Group
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Tetraoxane–Pyrimidine Nitrile Hybrids as Dual Stage Antimalarials

Autori: Rudi Oliveira, Rita C. Guedes, Patrícia Meireles, Inês S. Albuquerque, Lídia M. Gonçalves, Elisabete Pires, Maria Rosário Bronze, Jiri Gut, Philip J. Rosenthal, Miguel Prudêncio, Rui Moreira, Paul M. O’Neill, Francisca Lopes
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Targeting the Liver Stage of Malaria Parasites: A Yet Unmet Goal

Autori: Tiago Rodrigues, Miguel Prudêncio, Rui Moreira, Maria M. Mota, Francisca Lopes
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Editore: American Chemical Society
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The neurotrophic factor receptor RET drives haematopoietic stem cell survival and function

Autori: Diogo Fonseca-Pereira, Sílvia Arroz-Madeira, Mariana Rodrigues-Campos, Inês A. M. Barbosa, Rita G. Domingues, Teresa Bento, Afonso R. M. Almeida, Hélder Ribeiro, Alexandre J. Potocnik, Hideki Enomoto, Henrique Veiga-Fernandes
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Classification of current anticancer immunotherapies

Autori: Lorenzo Galluzzi, Erika Vacchelli, José-Manuel Bravo-San Pedro, Aitziber Buqué, Laura Senovilla, Elisa Elena Baracco, Norma Bloy, Francesca Castoldi, Jean-Pierre Abastado, Patrizia Agostinis, Ron N. Apte, Fernando Aranda, Maha Ayyoub, Philipp Beckhove, Jean-Yves Blay, Laura Bracci, Anne Caignard, Chiara Castelli, Federica Cavallo, Estaban Celis, Vincenzo Cerundolo, Aled Clayton, Mario P. Colombo, Lisa Coussens, Madhav V. Dhodapkar, Alexander M. Eggermont, Douglas T. Fearon, Wolf H. Fridman, Jitka Fučíková, Dmitry I. Gabrilovich, Jérôme Galon, Abhishek Garg, François Ghiringhelli, Giuseppe Giaccone, Eli Gilboa, Sacha Gnjatic, Axel Hoos, Anne Hosmalin, Dirk Jäger, Pawel Kalinski, Klas Kärre, Oliver Kepp, Rolf Kiessling, John M. Kirkwood, Eva Klein, Alexander Knuth, Claire E. Lewis, Roland Liblau, Michael T. Lotze, Enrico Lugli, Jean-Pierre Mach, Fabrizio Mattei, Domenico Mavilio, Ignacio Melero, Cornelis J. Melief, Elizabeth A. Mittendorf, Lorenzo Moretta, Adekunke Odunsi, Hideho Okada, Anna Karolina Palucka, Marcus E. Peter, Kenneth J. Pienta, Angel Porgador, George C. Prendergast, Gabriel A. Rabinovich, Nicholas P. Restifo, Naiyer Rizvi, Catherine Sautès-Fridman, Hans Schreiber, Barbara Seliger, Hiroshi Shiku, Bruno Silva-Santos, Mark J. Smyth, Daniel E. Speiser, Radek Spisek, Pramod K. Srivastava, James E. Talmadge, Eric Tartour, Sjoerd H. Van Der Burg, Benoît J. Van Den Eynde, Richard Vile, Hermann Wagner, Jeffrey S. Weber, Theresa L. Whiteside, Jedd D. Wolchok, Laurence Zitvogel, Weiping Zou, Guido Kroemer
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Editore: Impact Journals
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Distribution of Pilus Islands in Streptococcus agalactiae That Cause Human Infections: Insights into Evolution and Implication for Vaccine Development

Autori: E. R. Martins, A. Andreu, J. Melo-Cristino, M. Ramirez
Pubblicato in: Clinical and Vaccine Immunology, Numero 20/2, 2013, Pagina/e 313-316, ISSN 1556-6811
Editore: American Society for Microbiology
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BAFF and TACI Gene Expression Are Increased in Patients with Untreated Very Early Rheumatoid Arthritis

Autori: R. A. Moura, H. Canhao, J. Polido-Pereira, A. M. Rodrigues, M. Navalho, A. F. Mourao, C. Resende, R. Campanilho-Marques, J. Madruga Dias, J. A. P. da Silva, L. Graca, J. E. Fonseca
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Bioinformatics in bacterial molecular epidemiology and public health: databases, tools and the next-generation sequencing revolution

Autori: J. A. Carriço, A. J. Sabat, A.W. Friedrich, Mário Ramirez
Pubblicato in: Eurosurveillance, 2013, ISSN 1560-7917
Editore: EUR CENTRE DIS PREVENTION & CONTROL

Towards an advanced therapy medicinal product based on mesenchymal stromal cells isolated from the umbilical cord tissue: quality and safety data

Autori: José Paulo Martins, Jorge Miguel Santos, Joana Marto de Almeida, Mariana Alves Filipe, Mariana Vargas Teixeira de Almeida, Sílvia Cristina Paiva Almeida, Ana Água-Doce, Alexandre Varela, Mari Gilljam, Birgitta Stellan, Susanne Pohl, Kurt Dittmar, Werner Lindenmaier, Evren Alici, Luís Graça, Pedro Estilita Cruz, Helder Joaquim Cruz, Rita Nogueira Bárcia
Pubblicato in: Stem Cell Research & Therapy, Numero 5/1, 2014, Pagina/e 9, ISSN 1757-6512
Editore: BioMed Central
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Human FOXN1-Deficiency Is Associated with αβ Double-Negative and FoxP3+ T-Cell Expansions That Are Distinctly Modulated upon Thymic Transplantation

Autori: Adriana S. Albuquerque, José G. Marques, Susana L. Silva, Dario Ligeiro, Blythe H. Devlin, Jacques Dutrieux, Rémi Cheynier, Claudio Pignata, Rui M. M. Victorino, M. Louise Markert, Ana E. Sousa
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Driving IL-17+ γδ T-cell migration in allergic reactions: A new “inflammatory” role for the “homeostatic” chemokine CCL25

Autori: Bruno Silva-Santos
Pubblicato in: European Journal of Immunology, Numero 42/5, 2012, Pagina/e 1097-1101, ISSN 0014-2980
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Phylogenetic and clonality analysis of Bacillus pumilus isolates uncovered a highly heterogeneous population of different closely related species and clones

Autori: Raquel Branquinho, Luís Meirinhos-Soares, João A. Carriço, Manuela Pintado, Luísa V. Peixe
Pubblicato in: FEMS Microbiology Ecology, Numero 90/3, 2014, Pagina/e 689-698, ISSN 0168-6496
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miR-363-5p regulates endothelial cell properties and their communication with hematopoietic precursor cells

Autori: Ana Costa, Joana Afonso, Catarina Osório, Ana L Gomes, Francisco Caiado, Joana Valente, Sandra I Aguiar, Francisco Pinto, Mário Ramirez, Sérgio Dias
Pubblicato in: Journal of Hematology & Oncology, Numero 6/1, 2013, Pagina/e 87, ISSN 1756-8722
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Differences between Macrolide-Resistant and -Susceptible Streptococcus pyogenes: Importance of Clonal Properties in Addition to Antibiotic Consumption

Autori: C. Silva-Costa, A. Friaes, M. Ramirez, J. Melo-Cristino
Pubblicato in: Antimicrobial Agents and Chemotherapy, Numero 56/11, 2012, Pagina/e 5661-5666, ISSN 0066-4804
Editore: American Society for Microbiology
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Malaria infections: What and how can mice teach us

Autori: Vanessa Zuzarte-Luis, Maria M. Mota, Ana M. Vigário
Pubblicato in: Journal of Immunological Methods, Numero 410, 2014, Pagina/e 113-122, ISSN 0022-1759
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Establishment of Murine Gammaherpesvirus Latency in B Cells Is Not a Stochastic Event

Autori: Jérémie Decalf, Cristina Godinho-Silva, Diana Fontinha, Sofia Marques, J. Pedro Simas
Pubblicato in: PLoS Pathogens, Numero 10/7, 2014, Pagina/e e1004269, ISSN 1553-7366
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B7-CD28 Costimulatory Signals Control the Survival and Proliferation of Murine and Human T Cells via IL-2 Production

Autori: J. C. Ribot, A. deBarros, L. Mancio-Silva, A. Pamplona, B. Silva-Santos
Pubblicato in: The Journal of Immunology, Numero 189/3, 2012, Pagina/e 1202-1208, ISSN 0022-1767
Editore: American Association of Immunologists
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Induction of Prophages by Fluoroquinolones in Streptococcus pneumoniae: Implications for Emergence of Resistance in Genetically-Related Clones

Autori: Elena López, Arnau Domenech, María-José Ferrándiz, Maria João Frias, Carmen Ardanuy, Mario Ramirez, Ernesto García, Josefina Liñares, Adela G. de la Campa
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Chemical Interrogation of the Malaria Kinome

Autori: Emily R. Derbyshire, Vanessa Zuzarte-Luís, Andreia D. Magalhães, Nobutaka Kato, Paul C. Sanschagrin, Jinhua Wang, Wenjun Zhou, Chandrasekhar V. Miduturu, Ralph Mazitschek, Piotr Sliz, Maria M. Mota, Nathanael S. Gray, Jon Clardy
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Editore: John Wiley & Sons Ltd.
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Guidelines for the use of flow cytometry

Autori: Marc Veldhoen
Pubblicato in: Immunity, Inflammation and Disease, Numero 5/4, 2017, Pagina/e 384-385, ISSN 2050-4527
Editore: WILEY
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Invasive infections due to Streptococcus pyogenes: seasonal variation of severity and clinical characteristics, Iceland, 1975 to 2012

Autori: L B Olafsdottir, H Erlendsdóttir, J Melo-Cristino, D M Weinberger, M Ramirez, K G Kristinsson, M Gottfredsson
Pubblicato in: EuroSurveillance, Numero 52, 2014, ISSN 1560-7917
Editore: EUR CENTRE DIS PREVENTION & CONTROL

Tumor cell recognition by γδ T lymphocytes

Autori: Daniel V. Correia, Antonio C. Lopes, Bruno Silva-Santos
Pubblicato in: OncoImmunology, Numero 2/1, 2013, Pagina/e e22892, ISSN 2162-4011
Editore: Landes Bioscience
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Differentiation of Type 1 ILCs from a Common Progenitor to All Helper-like Innate Lymphoid Cell Lineages

Autori: Christoph S.N. Klose, Melanie Flach, Luisa Möhle, Leif Rogell, Thomas Hoyler, Karolina Ebert, Carola Fabiunke, Dietmar Pfeifer, Veronika Sexl, Diogo Fonseca-Pereira, Rita G. Domingues, Henrique Veiga-Fernandes, Sebastian J. Arnold, Meinrad Busslinger, Ildiko R. Dunay, Yakup Tanriver, Andreas Diefenbach
Pubblicato in: Cell, Numero 157/2, 2014, Pagina/e 340-356, ISSN 0092-8674
Editore: Cell Press
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Targeting Host Factors to Circumvent Anti-Malarial Drug Resistance

Autori: Miguel Prudencio, Maria M. Mota
Pubblicato in: Current Pharmaceutical Design, Numero 19/2, 2013, Pagina/e 290-299, ISSN 1381-6128
Editore: Bentham Science Publishers
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A Novel Flow Cytometric Hemozoin Detection Assay for Real-Time Sensitivity Testing of Plasmodium falciparum

Autori: Maria Rebelo, Claudia Sousa, Howard M. Shapiro, Maria M. Mota, Martin P. Grobusch, Thomas Hänscheid
Pubblicato in: PLoS ONE, Numero 8/4, 2013, Pagina/e e61606, ISSN 1932-6203
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Novel Potent Metallocenes against Liver Stage Malaria

Autori: J. Matos, F. P. da Cruz, E. Cabrita, J. Gut, F. Nogueira, V. E. do Rosario, R. Moreira, P. J. Rosenthal, M. Prudencio, P. Gomes
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Simple, sensitive and quantitative bioluminescence assay for determination of malaria pre-patent period

Autori: Vanessa Zuzarte-Luis, Joana Sales-Dias, Maria M Mota
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Novel Role of the Antimicrobial Peptide LL-37 in the Protection of Neutrophil Extracellular Traps against Degradation by Bacterial Nucleases

Autori: Ariane Neumann, Lena Völlger, Evelien T.M. Berends, E. Margo Molhoek, Daphne A.C. Stapels, Marika Midon, Ana Friães, Alfred Pingoud, Suzan H.M. Rooijakkers, Richard L. Gallo, Matthias Mörgelin, Victor Nizet, Hassan Y. Naim, Maren von Köckritz-Blickwede
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Natural Cytotoxicity Receptors: Broader Expression Patterns and Functions in Innate and Adaptive Immune Cells

Autori: Kelly Hudspeth, Bruno Silva-Santos, Domenico Mavilio
Pubblicato in: Frontiers in Immunology, Numero 4, 2013, ISSN 1664-3224
Editore: Frontiers Editorial Office
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Probing the aurone scaffold against Plasmodium falciparum: Design, synthesis and antimalarial activity

Autori: Marta P. Carrasco, Ana S. Newton, Lídia Gonçalves, Ana Góis, Marta Machado, Jiri Gut, Fátima Nogueira, Thomas Hänscheid, Rita C. Guedes, Daniel J.V.A. dos Santos, Philip J. Rosenthal, Rui Moreira
Pubblicato in: European Journal of Medicinal Chemistry, Numero 80, 2014, Pagina/e 523-534, ISSN 0223-5234
Editore: Elsevier BV
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Spartan: A Comprehensive Tool for Understanding Uncertainty in Simulations of Biological Systems

Autori: Kieran Alden, Mark Read, Jon Timmis, Paul S. Andrews, Henrique Veiga-Fernandes, Mark Coles
Pubblicato in: PLoS Computational Biology, Numero 9/2, 2013, Pagina/e e1002916, ISSN 1553-734X
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Human regulatory T-cell development is dictated by Interleukin-2 and -15 expressed in a non-overlapping pattern in the thymus

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Dynamic Metabolic State of Tissue Resident CD8 T Cells

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Mitochondria maintain controlled activation state of epithelial-resident T lymphocytes

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Serotype changes in adult invasive pneumococcal infections in Portugal did not reduce the high fraction of potentially vaccine preventable infections

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Scarlet Fever Is Caused By a Limited Number of Streptococcus pyogenes Lineages and Is Associated with the Exotoxin Genes ssa, speA and speC

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Immunology: Skin T Cells Switch Identity to Protect and Heal

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Anthracyclines Induce DNA Damage Response-Mediated Protection against Severe Sepsis

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A Novel Way to Grow Hemozoin-Like Crystals In Vitro and Its Use to Screen for Hemozoin Inhibiting Antimalarial Compounds

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PRIMACINS, N-cinnamoyl-primaquine conjugates, with improved liver-stage antimalarial activity

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Stabilization of Myc through Heterotypic Poly-Ubiquitination by mLANA Is Critical for γ-Herpesvirus Lymphoproliferation

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At the Bench: Preclinical rationale for exploiting NK cells and T lymphocytes for the treatment of high-risk leukemias

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Guidelines for the use of flow cytometry and cell sorting in immunological studies *

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Essential, dose-dependent role for the transcription factor Gata3 in the development of IL-5+ and IL-13+ type 2 innate lymphoid cells

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Differentiation and Activation of γδ T Lymphocytes: Focus on CD27 and CD28 Costimulatory Receptors

Autori: Julie C. Ribot, Bruno Silva-Santos
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Quantification of Sporozoite Invasion, Migration, and Development by Microscopy and Flow Cytometry

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Endemic SARS-CoV-2 will maintain post-pandemic immunity

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Academic labs supporting COVID‐19 diagnostics

Autori: Marc Veldhoen, Vanessa Zuzarte‐Luis
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